• Tuberculosis and Respiratory Diseases
• /
• v.83 no.1
• /
• pp.31-41
• /
• 2020

Background: Chronic cough is defined as a cough lasting more than 8 weeks and socio-economic burden of chronic cough is enormous. The characteristics of chronic cough in Korea are not well understood. The Korean Academy of Tuberculosis and Respiratory Diseases (KATRD) published guidelines on cough management in 2014. The current study evaluated the clinical characteristics of chronic cough in Korea and the efficacy of the KATRD guidelines. Methods: This was a multi-center, retrospective observational study conducted in Korea. The participants were over 18 years of age. They had coughs lasting more than 8 weeks. Subjects with current pulmonary diseases, smokers, exsmokers with more than 10 pack-years or who quit within the past 1 year, pregnant women, and users of cough-inducing medications were excluded. Evaluation and management of cough followed the KATRD cough-management guidelines. Results: Participants with chronic cough in Korea showed age in the late forties and cough duration of more than 1 year. Upper airway cough syndrome was the most common cause of cough, followed by cough-variant asthma (CVA). Gastro-esophageal reflux diseases and eosinophilic bronchitis were less frequently observed. Following the KATRD cough-management guidelines, 91.2% of the subjects improved after 4 weeks of treatment. Responders were younger, had a longer duration of cough, and an initial impression of CVA. In univariate and multivariate analyses, an initial impression of CVA was the only factor related to better treatment response. Conclusion: The causes of chronic cough in Korea differed from those reported in other countries. The current Korean guidelines proved efficient for treating Korean patients with chronic cough.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.6
• /
• pp.322-331
• /
• 2019

This study was conducted to examine the correlations between knowledge and compliance of cough etiquette, and to identify the influencing factors on compliance of cough etiquette in nursing students. This was a descriptive study. Data were collected from september 3 to 14, 2018 in 173 nursing students. Data were collected through personal interviews using a questionnaire. Data were analyzed using t-test, one-way ANOVA, Kruskal-wallis test, Pearson's correlation coefficients, and stepwise multiple regression. Knowledge of cough etiquette according to the droplet infection related characteristics showed significant differences in hand washing. Compliance of cough etiquette according to the droplet infection related characteristics showed significant differences in carrying a tissue, carrying a handkerchief, hand washing, need education for cough etiquette. Knowledge of cough etiquette showed significant positive correlations with compliance of cough etiquette. Knowledge of cough etiquette, carrying a handkerchief, need education for cough etiquette, which accounted for 22% of the variance, were significant predictors influencing compliance of cough etiquette in nursing students. To improve compliance of cough etiquette in nursing students, it is necessary to carry handkerchief and to develop a education program that can raise knowledge with cough etiquette.

• Asian-Australasian Journal of Animal Sciences
• /
• v.23 no.8
• /
• pp.1096-1104
• /
• 2010

This bio-acoustic study was aimed at classifying the different porcine wasting diseases through sound analysis with emphasis given to differences in the acoustic footprints of coughs in porcine circo virus type 2 (PCV2), porcine reproductive and respiratory syndrome (PRRS) virus and Mycoplasma hyopneumoniae (MH) - infected pigs from a normal cough. A total of 36 pigs (Yorkshire${\times}$Landrace${\times}$Duroc) with average weight ranging between 25-30 kg were studied, and blood samples of the suspected infected pigs were collected and subjected to serological analysis to determine PCV2, PRRS and MH. Sounds emitted by coughing pigs were recorded individually for 30 minutes depending on cough attacks by a digital camcorder placed within a meter distance from the animal. Recorded signals were digitalized in a PC using the Cool Edit Program, classified through labeling method, and analyzed by one-way analysis of variance and discriminant analysis. Input features after classification showed that normal cough had the highest pitch level compared to other infectious diseases (p<0.002) but not statistically different from PRRS and MH. PCV2 differed statistically (p<0.002) from the normal cough and PRRS but not from MH. MH had the highest intensity and all coughs differed statistically from each other (p<0.0001). PCV2 was statistically different from others (p<0.0001) in formants 1, 2, 3 and 4. There was no statistical difference in duration between different porcine diseases and the normal cough (p>0.6863). Mechanisms of cough sound creation in the airway could be used to explain these observed acoustic differences and these findings indicated that the existence of acoustically different cough patterns depend on causes or the animals' respiratory system conditions. Conclusively, differences in the status of lungs results in different cough sounds. Finally, this study could be useful in supporting an early detection method based on the on-line cough counter algorithm for the initial diagnosis of sick animals in breeding farms.

• The Journal of Internal Korean Medicine
• /
• v.21 no.2
• /
• pp.213-217
• /
• 2000

Objective : To observe the effect of Bokryungbosim-tang on the cough, cough patients medicine Bokryungbosim-tang. Methods : A clinical observation was done on 30 case of cough patients, treated by Bokryungbosim-tang, who were hospitalized frome January, 1. 1999 to December, 31, 1999 at the department of IKSAN Oriental Medicine Hospital, Wonkwang University and Pak Cheon Soo oriental medical clinic. Results : The effect of treated by Bokryungbosim-tang is that excellent was 19 case(63.33%), good 3 case(10%), fair 3 case(10%) and poor 5 case(16.66%). Conclusions : These results indicate that the effect of Bokryungbosim-tang on the cough is excellent.

• The Journal of Korean Medicine
• /
• v.21 no.4
• /
• pp.248-252
• /
• 2000

The subject was a 70-year-old man who was suffering from productive cough after stroke. His symptoms were night cough, thick sputum production, reddened tongue and night sweat. The subject was diagnosed as having a deficiency of Yin, and was treated with Chungsangboha-tang(Qingshangbuxia-tang). A decrease in the severity of the subject's cough and sputum were observed, and $O_2$ saturation increased. In this case Chungsangboha-tang(Qingshangbuxia-tang) was effective on the patient with night cough, thick sputum production, reddened tongue and night sweat due to deficiency of Yin after stroke.

• The Korean Journal of Pharmacology
• /
• v.13 no.2
• /
• pp.61-65
• /
• 1977

We tried $Cofrel^{\circledR}$ ($Pyrexyl^{\circledR}$ 1-(2-benzyl phenoxy)-2-piperidino-propane phosphate) which is non-narcotic, to evaluate its clinical effect on cough due to respiratory tract diseases-35 cases. 1) Thirty two cases among 35 cases disclosed remarkable effectiveness (91.4% of efficacy) 2) It was almost equally effective in dry cough, productive cough and barking cough. 3) Speed of response was very rapid in 21 cases(60.0) moderately rapid in 12 cases(34.3%). 4) Palatability were excellent in all cases and side effect was not observed. It is very difficult to evaluate effectiveness of anti-tussive drug. However, we concluded that Cofrel is a quite effective medicament for cough in respiratory diseases in children.

• 대한상한금궤의학회지
• /
• v.5 no.1
• /
• pp.31-43
• /
• 2013

Objective : This study evaluated the effect of Gui-Zhi-Tang(桂枝湯) on chronic cough. Methods : Three patients who had a chronic cough were diagnosed by the Shanghanlun(傷寒論) Six meridian patterns diagnostic system (六經診斷體系) and treated with Gui-Zhi-Tang(桂枝湯) based on Shang-han-lun's 12th and 15th text. The treatment lasted more than 4 weeks. The severity of Chronic cough was evaluated by the questionnaire(symptom severity assessment) before and after administration of each treatment term. Results : After the treatments, the patients' symptoms and results of the questionnaire improved. Conclusions : This case study showed an effectiveness of using Gui-Zhi-Tang on chronic cough.

• Journal of Sasang Constitutional Medicine
• /
• v.13 no.3
• /
• pp.126-133
• /
• 2001

Peumonia is the infection of the lungs. Bronchopneumonia is the infection of the bronchus. But their symtoms are simillar. I took care of a patient in bronchopneumonia. And then I reviewed Haemophilus influenzae and Soeumin's cough through west-east medicine books. Cough is divided with the outter disease and the inner disease on the pathology of the Korean Medicine(Sansang Constitutional Medicine). And the outter disease is divided with the outter symptom and the inner symptom. The inner disease is divided too. I wanted to discuss Soeumin's cough is the outter symptom of the outter disease and the inner disease. Finally the outter symptom of the outter disease must be applied with the thrapeutic method of the removal wind-cold and the elevation of YangGi in Soeumin's cough. And the outter symptom of the inner disease must be applied with the thrapeutic method of the heating AbdominalGi and the going down of EumGi in Soeumin's cough.

• Tuberculosis and Respiratory Diseases
• /
• v.84 no.4
• /
• pp.263-273
• /
• 2021

Cough is the most common respiratory symptom that can have various causes. It is a major clinical problem that can reduce a patient's quality of life. Thus, clinical guidelines for the treatment of cough were established in 2014 by the cough guideline committee under the Korean Academy of Tuberculosis and Respiratory Diseases. From October 2018 to July 2020, cough guidelines were revised by members of the committee based on the first guidelines. The purpose of these guidelines is to help clinicians efficiently diagnose and treat patients with cough. This article highlights the recommendations and summary of the revised Korean cough guidelines. It includes a revised algorithm for the evaluation of acute, subacute, and chronic cough. For a chronic cough, upper airway cough syndrome (UACS), cough variant asthma (CVA), and gastroesophageal reflux disease (GERD) should be considered in differential diagnoses. If UACS is suspected, first-generation antihistamines and nasal decongestants can be used empirically. In cases with CVA, inhaled corticosteroids are recommended to improve cough. In patients with suspected chronic cough due to symptomatic GERD, proton pump inhibitors are recommended. Chronic bronchitis, bronchiectasis, bronchiolitis, lung cancer, aspiration, intake of angiotensin-converting enzyme inhibitor, intake of dipeptidyl peptidase-4 inhibitor, habitual cough, psychogenic cough, interstitial lung disease, environmental and occupational factors, tuberculosis, obstructive sleep apnea, peritoneal dialysis, and unexplained cough can also be considered as causes of a chronic cough. Chronic cough due to laryngeal dysfunction syndrome has been newly added to the guidelines.

• Tuberculosis and Respiratory Diseases
• /
• v.72 no.2
• /
• pp.236-241
• /
• 2012

Cough syncope is characterized by the loss of consciousness occurring after vigorous coughings. There are approximately 90 reported cases of cough syncope within the medical literature. Most cases involving middle aged, overweight and chronic bronchitic male smokers. Although many studies have been published in the medical literature, the mechanism and pathophysiology for cough syncope has not been well established. Cough syncope is treated by correcting the underlying cause when identified, or by avoiding conditions that may cause the cough syncope. In addition, cough suppression modalities can also be used. We herein report 3 cases of cough syncope presenting in lung cancer patients.