• Title/Summary/Keyword: cost control

Search Result 5,864, Processing Time 0.039 seconds

Effect of protein transduction domain fused-bone morphogenetic protein-2 on bone regeneration in rat calvarial defects (단백질 전달 영역 융합-Bone Morphogenetic Protein-2가 백서 두개골 결손부에서 골 조직 재생에 미치는 효과)

  • Um, Yoo-Jung;Cho, Kyoo-Sung;Kim, Chong-Kwan;Choi, Seong-Ho;Chai, Jung-Kiu;Kim, Chang-Sung
    • Journal of Periodontal and Implant Science
    • /
    • v.38 no.2
    • /
    • pp.153-162
    • /
    • 2008
  • Purpose: Recombining bone morphogenetic protein (BMP) is usually acquiredfrom high level animals. Though this method is effective, its high cost limits its use. The purpose of this study was to evaluate the effect of bone morphogenetic protein-2 with protein transduction domain (BMP-2/PTD;TATBMP-2) on bone regeneration. Rat calvarial defect model and osteoblastic differentiation model using MC3T3 cell were used for the purpose of the study. Materials and Methods: MC3T3 cells were cultured until they reached a confluence stage. The cells were treated with 0, 0.1, 1, 10, 100, 500 ng/ml of BMP-2/PTD for 21 days and at the end of the treatment, osteoblastic differentiation was evaluated usingvon Kossa staining. An 8mm, calvarial, critical-size osteotomy defect was created in each of 48 male Spraque-Dawley rats (weight $250{\sim}300\;g$). Three groups of 16 animals each received either BMP-2/PTD (0.05mg/ml) in a collagen carrier, collagen only, or negative surgical control. And each group was divided into 2 and 8 weeks healing intervals. The groups were evaluated by histologic analysis(8 animals/group/healing intervals) Result: In osteoblastic differentiation evaluation test, a stimulatory effect of BMP-2/PTD was observed in 10ng/ml of BMP-2/PTD with no observation of dose-dependent manner. The BMP-2/PTD group showed enhanced local bone formation in the rat calvarial defect at 2 weeks. New bone was observed at the defect margin and central area of the defect. However, new bone formation was observed only in 50% of animals used for 2weeks. In addition, there was no new bone formation observed at 8 weeks. Conclusion: The results of the present study indicated that BMP-2/PTD(TATBMP-2) have an positive effect on the bone formation in vitro and in vivo. However, further study should be conducted for the reproducibility of the outcomes.

Mutual Authentication Method between Wireless Mesh Enabled MSAPs in the Next-generation TICN (차세대 전술정보통신체계에서의 무선 메쉬 MSAP 노드 간 상호 인증 기법)

  • Son, Yu-Jin;Bae, Byoung-Gu;Shon, Tae-Shik;Ko, Young-Bae;Lim, Kwang-Jae;Yun, Mi-Young
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.37 no.5B
    • /
    • pp.385-394
    • /
    • 2012
  • The tactical mobile communication network, which comprises a part of the next-generation Tactical Information and Communication Network (TICN), provides means of communication and control for Tactical Multi-Functional Terminals (TMFT) belonging to a Mobile Subscriber Access Point (MSAP). The next-generation of MSAP is capable of constructing a backbone network via LCTR and HCTR directional antennas. At the same time, WMN modules are used to create and manage a wireless mesh backbone. When directional antennas are used in mobile environments, seamless services cannot be efficiently supported as the movement of the node prevents the angle of the antenna to constantly match. Therefore, data communication through the wireless mesh networks is required to provide direct communication between mobile MSAPs. Accordingly, mutual authentication and data encryption mechanisms are required to provide reliable data transmission in this environment. To provide efficient mutual authentication between MSAP devices, the process of verifying a certificate of the other MSAP device through its own authentication server is required. This paper proposes mutual authentication mechanisms where the MSAP requiring authentication and the MSAP that permits it initiates low-cost and efficient authentication in a distributed way. More specifically, we propose a method of applying EAP-ELS (Extensible Authentication Protocol-Transport Layer Security) in the next-generation TICN.

Attractant Effect of Trap Logs Treated with Ethanol to Platypus koryoensis (Coleoptera: Platypodidae) (에탄올 처리에 의한 광릉긴나무좀(Platypus koryoensis) 유인목 효율 증대)

  • Son, Su-Yeon;Lee, Sun Keun;Seo, Sang-Tae
    • Korean journal of applied entomology
    • /
    • v.54 no.4
    • /
    • pp.443-448
    • /
    • 2015
  • The attractant effect to Platypus koryoensis (Murayama), an insect vector of Korean oak wilt disease, was determined using a multi-funnel trap and trap logs treated with ethanol and ethanol extract of the bark of the Mongolian oak Quercus mongolica (Fisher). The number of entrance holes in ethanol and bark ethanol extract treatments was higher than that in the control (blank bottle). However, the number of entrance holes in ethanol and bark ethanol extract treatments was not significantly different. The number of entrance holes in the logs increased with increase in diameter of the logs. The lower part of the trap logs had significantly more number of entrance holes than that in the upper part (p < 0.05). The lower part of trap logs tends to be rarely exposed to direct sunlight resulting in desiccation of the logs, which in turn provides good conditions for microbial growth, a food source for P. koryoensis. The results show, that ethanol could be used effectively in the monitoring and maintenance of P. koryoensis because of the cheaper cost of ethanol than bark ethanol extracts, and thus, having a higher economical advantage. Further research of oak bark ethanol extracts is necessary to improve its efficiency.

CAPACITY EXPANSION MODELING OF WATER SUPPLY IN A PLANNING SUPPORT SYSTEM FOR URBAN GROWTH MANAGEMENT (도시성장관리를 위한 계획지원체계에서 상수도의 시설확장 모델링)

  • Hyong-Bok, Kim
    • Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
    • /
    • 1995.12a
    • /
    • pp.9-21
    • /
    • 1995
  • A planning support system enhances our ability to use water capacity expansion as an urban growth management strategy. This paper reports the development of capacity expansion modeling of water supply as part of the continuing development of such a planning support system (PEGASUS: Planning Environment for Generation and Analysis of Spatial Urban Systems) to incorporate water supply, This system is designed from the understanding that land use and development drive the demand for infrastructure and infrastructure can have a significant influence on the ways in which land is developed and used. Capacity expansion Problems of water supply can be solved in two ways: 1) optimal control theory, and 2) mixed integer nonlinear programming (MINLP). Each method has its strengths and weaknesses. In this study the MINLP approach is used because of its strength of determining expansion sizing and timing simultaneously. A dynamic network optimization model and a water-distribution network analysis model can address the dynamic interdependence between water planning and land use planning. While the water-distribution network analysis model evaluates the performance of generated networks over time, the dynamic optimization model chooses alternatives to meet expanding water needs. In addition, the user and capacity expansion modeling-to-generate-alternatives (MGA) can generate alternatives. A cost benefit analysis module using a normalization technique helps in choosing the most economical among those alternatives. GIS provide a tool for estimating the volume of demanded water and showing results of the capacity expansion model.

  • PDF

Implementation of Hypervisor for Virtualizing uC/OS-II Real Time Kernel (uC/OS-II 실시간 커널의 가상화를 위한 하이퍼바이저 구현)

  • Shin, Dong-Ha;Kim, Ji-Yeon
    • Journal of the Korea Society of Computer and Information
    • /
    • v.12 no.5
    • /
    • pp.103-112
    • /
    • 2007
  • In this paper, we implement a hypervisor that runs multiple uC/OS-II real-time kernels on one microprocessor. The hypervisor virtualizes microprocessor and memory that are main resources managed by uC/OS-II kernel. Microprocessor is virtualized by controlling interrupts that uC/OS-II real-time kernel handles and memory is virtualized by partitioning physical memory. The hypervisor consists of three components: interrupt control routines that virtualize timer interrupt and software interrupt, a startup code that initializes the hypervisor and uC/OS-II kernels, and an API that provides communication between two kernels. The original uC/OS-II kernel needs to be modified slightly in source-code level to run on the hypervisor. We performed a real-time test and an independent computation test on Jupiter 32-bit EISC microprocessor and showed that the virtualized kernels run without problem. The result of our research can reduce the hardware cost, the system space and weight, and system power consumption when the hypervisor is applied in embedded applications that require many embedded microprocessors.

  • PDF

An Electronic Keyboard Instrument Using PC MIDI and USB Interface (PC MIDI와 USB Interface를 이용한 전자건반악기 개발)

  • Lim, Gi-Jeong;Lee, Jung-Chul
    • Journal of the Korea Society of Computer and Information
    • /
    • v.16 no.11
    • /
    • pp.85-93
    • /
    • 2011
  • The music education improves the creative talent, social skills and academic achievement of the students. For the efficient music education, the learner centered study is highly recommended rather than the passive education, which supports self-control in selecting teaching materials, learning patterns and speed. For the successful self learning, it is requested to develop the collaborative educational learning tools, especially electronic collaborators such as H/W and S/W. Though there exist many commercialized electronic instruments and the PC MIDI based softwares, these tools have some limits and problems for the primary student to learn playing the musical instrument by himself. In this paper, we propose a supporting tool implementation method using an electronic keyboard instrument with USB Interface and PC-based software to help the primary student to learn playing the musical instrument. We implemented an electronic keyboard instrument module compactly and at low cost using a PIC18F4550 MCU. PC based software was developed to edit musical score, process the MIDI information, and interact with the electronic keyboard instrument module. This tool can offer a similar keyboard instrument environment and can be incorporated with self learning contents.

Improvement of Seismic Performance of Long-span Bridges using Complex Dampers (복합감쇠기를 이용한 장대교량의 내진성능향상)

  • Ha, Dong-Ho;Park, Kwan-Soon;Park, Won-Suk;Pyeon, Mu-Wook
    • Journal of the Earthquake Engineering Society of Korea
    • /
    • v.11 no.3 s.55
    • /
    • pp.53-62
    • /
    • 2007
  • This paper presents a new vibration control method for long-span bridges using complex damper system. The new system presents simple mechanical configuration with oil and elasto-plastic dampers which have velocity and displacement dependency in vibration energy absorbing. This system can produce various damping forces according to the applied external forces by the velocity and displacement-dependent characteristics of the dampers. The oil damper dissipates vibration energy for relatively frequent and small amplitude like in the case for small to moderate earthquakes, whereas the elasto-plastic damper system works for rare and large amplitude vibration such as high seismic excitation. Thus, the proposed system exhibits the advantage of low cost with high performance since the roles of the two different dampers are effectively separated. A numerical model is established for the complex damper system, and the response characteristics and effectiveness of the proposed system are presented through numerical simulations. Numerical results show that the proposed complex damper system can significantly improve the seismic performance of long-span bridge structures with much more effective damping mechanism than single conventional passive damper systems.

The Cell Resequencing Buffer for the Cell Sequence Integrity Guarantee for the Cyclic Banyan Network (사이클릭 벤얀 망의 셀 순서 무결성 보장을 위한 셀 재배열 버퍼)

  • 박재현
    • Journal of the Institute of Electronics Engineers of Korea TC
    • /
    • v.41 no.9
    • /
    • pp.73-80
    • /
    • 2004
  • In this paper, we present the cell resequencing buffer to solve the cell sequence integrity problem of the Cyclic banyan network that is a high-performance fault-tolerant cell switch. By offering multiple paths between input ports and output ports, using the deflection self-routing, the Cyclic banyan switch offer high reliability, and it also solves congestion problem for the internal links of the switch. By the way, these multiple paths can be different lengths for each other. Therefore, the cells departing from an identical source port and arriving at an identical destination port can reach to the output port as the order that is different from the order arriving at input port. The proposed cell resequencing buffer is a hardware sliding window mechanism. to solve such cell sequence integrity problem. To calculate the size of sliding window that cause the prime cost of the presented device, we analyzed the distribution of the cell delay through the simulation analyses under traffic load that have a nonuniform address distribution that express tile Property of traffic of the Internet. Through these analyses, we found out that we can make a cell resequencing buffer by which the cell sequence integrity is to be secured, by using a, few of ordinary memory and control logic. The cell resequencing buffer presented in this paper can be used for other multiple paths switching networks.

A Newer Short Synthesis of dl-Muscone(Ⅰ) (새로운 짧은 경로로의 dl-Muscone 합성(Ⅰ))

  • Im, D.S.;Shin, D.H.;Park, D.K.
    • Journal of the Korean Chemical Society
    • /
    • v.40 no.4
    • /
    • pp.243-248
    • /
    • 1996
  • New routes have been developed for the practical syntheses of dl-Muscone(1) employing cyclopentadecanone(2) as the starting material. In this experiment, addition of bromine to cyclopentadecanone in dried E. Ether solution with a trace of $AlCl_3$ as the catalyst were produced 2-bromocyclopentadecanone(3). This process was enhanced formation of regioselective enolate anion at $C_2$ position. 2-Bromocyclopentadecanone was put into $Li_2CO_3$-LiBr-DMF solution at 140∼150$^{\circ}C$, were produced trans- and cis-2-cyclopentadecen-1-one(4) mixture. Other by-products were reduced by control of reaction temperature and time. Trans- and cis-2-cyclopentadecen-1-one(4) mixture was directly put into dried E. Ether solvent and induce to react dropwise with $CH_3MgBr-Cu_2Cl_2$ complex, all of them got into 1,4-addition, dl-Muscone (1) was formed as the result. Conculsion, through three steps procedure from cyclopentadecanone(2) to dl-Muscone(1), the pure dl-Muscone was obtained with the high proportion of 85%, and synthetic cost was able to be much lower than any other conventional methods as there were no chemical separating steps.

  • PDF

Investment Analysis of the Modernized Green Houses in Korea (현대화 온실의 투자분석)

  • Lee, Kwang-Won;Lim, Jae-Hwan;Lee, Doo-Hee
    • Korean Journal of Agricultural Science
    • /
    • v.24 no.2
    • /
    • pp.170-181
    • /
    • 1997
  • The number of modernized green houses have been increased to produce high quality and high-payoff farm products. The unit investment costs per pyeong($3.3058m^2$) for building a glass house was estimated at 449 thousand won. On the other hand, the unit prices for the PC house with iron frame and the vynil house with automatic control system were revealed 365 thousand won and 93 thousand won respectively. The main objective of the study was to identify the financial feasibility of the green house investment prevailed in rural area. At present, some farmers have selected the green house without any consideration of profitability of crops and accessiblity of their fanning practices and technology. For the soundness of green house cultivation and management, the indices of finacial efficiency for the modernized green houses were necessary. The decesion making criteria such as NPV(Net Present Value), IRR(Internal Rate of Return), B/C Ratio and Payback Period were analyzed for the individual high investment facilities considering the present farmer's technology and on-farm benefits and costs. The results of the feasibility analysis of green houses were as follows: 1. In case of 100% private burden of the investment costs, NPV revealed only positive value for the vinyl house with automatic system and IRR for the house was also estimated at more than 10% and B/C Ratio was amounted to more than 1.0. On the other hand, the other glass and PC houses showed negative NPV and unacceptable B/C ratio and IRR. 2. In case of the following terms and conditions as 50% Government subsidy, 20% loans and 30% farmers burden of the total investment cost, all the green houses showed acceptable IRR, B/C Ratio and NPV. 3. The financial feasibility of the glass house was acceptable in tomato cultivation rather than in cucumber cultivation. The payback periods of cucumber were represented as 8.9 years for glass house, 8.5 years for PC house and 4.1 years for vinyl house with automatic system respectively. In conclution, the glass and PC house cultivation of high value vegetables were only acceptable under the Goverment subsidy and loan systems from the view point of farmer's financial situations. On account of the unacceptable economic rate of return, the government subsidy and loan policy for glass house cultivation should be transfered to the vinyl and pc houses in the future.

  • PDF