• Journal of the Society of Cosmetic Scientists of Korea
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• v.28 no.2
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• pp.55-57
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• 2002

The fabrication, characterization and manipulation of nanosystems brings together physics, chemistry, materials science and biology in an unprecedented way, Phenomena occurring in such systems are fundamental to the workings of electronic devices, but also to living organisms. The ability to fabricate nanostructures is essential in the further development of functional devices that incorporate nanoscale features. Even more essential is the ability to introduce a wide range of chemical and materials flexibility into these structures to build up more complex nanostructures that can ultimately rival biological nanosystems. In this respect, polymers are potentially ideal nanoscale building blocks because of their length scale, well-defined architecture, controlled synthesis, ease of processing and wide range of chemical functionality that can be incorporated. In this presentation, we will look at a number of promising polymer-based nanofabrication strategies that have been developed recently, with an emphasis on those techniques that incorporate nanostructured polymers into devices and that exploit intrinsic polymer properties.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.23 no.2
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• pp.97-117
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• 1997

L-Ascorbic acid 및 그 유도체는 항산화 작용과 미백작용 및 섬유아세포의 생장 촉진과 콜라젠 생합성의 증가시키는 효과가 있으므로 화장품에서 오래 전부터 사용되어 왔다. 본 연구에서는 생체에 대한 안전성과 안정성이 우수한 L-Ascorbic acid 유도체를 개발하기 위하여 인지질과 유사하게 L-Ascorbic acid 에 3-Aminopropane phosphoric acid를 결합하여 L-Ascorbic acid-3-aminopropane phosphoric acid diester를 합성하였다. ASA-APPA 는 2-Chlorotetrahydro-2H-1, 3, 2-oxazaphosphorine P-oxide 와 5, 6-isopropylidene L-Ascorbic acid 를 반응 시킨 후 산 사수분해 반응을 통하여 얻을 수 있었다. ASA-APPA는 수용액에서 안정성이 우수하였으며, 독성실험에서 무독성 물질이며, 인체 첩포 실험에서도 무자극 물질임을 확인하였다. 그리고, ASA-APPA 는 L-Ascorbic acid 와 3-APPA 의 혼합물과 거의 유사한 섬유아세포의 증식효과를 나타내었으며, melanoma 에 대한 멜라닌 생성 억제 실험에서 L-Ascorbic acid phosphate magnesium salt 와 유사한 효과를 보였다. 따라서 ASA-APPA 는 멜라닌 생성 억제 효과와 섬유아세포의 증식 효과를 갖는 새로운 화장품 원료로서 사용이 가능할 것으로 생각된다.

• Journal of the Korean Applied Science and Technology
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• v.33 no.4
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• pp.667-675
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• 2016

Nanoemulsions are actively used in several applications for pharmaceutical, cosmetic and chemical industries. In this study, we propose the use of microfluidizer known as high pressure homogenizer to prepare lipid nanoemulsion as a potent cosmetic delivery carrier. The lipid nanoemulsions were prepared by O/W emulsion with hydrogenated lecithin and different type of oils. Effects of oil type on the stability of the lipid nanoemulsion were investigated with Dynamic Light Scattering (DLS) and Zeta-potential. Arbutin was used as model drug for transdermal administration through hairless mouse skin. Transdermal arbutin delivery using the lipid nanoemulsions was studied with HPLC method.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.192-199
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• 2003

Trimethylglycine, commonly named betaine, is the most simple amphoteric molecule. It is completely vegetal (1,2), as it is produced in the sugar industry by industrial chromatography of molasses. While abundantly used in foods and diet supplements, many interesting applications in cosmetics have recently been investigated, like its capability to increase the volume and stability of foams in surfactant solutions. For its special chemical structure (it is the internal salt of a weak acid and a strong alkali) trimethylglycine is a solvent and buffering agent for strong acids and Lewis' acids. It allows to improve the efficiency of $\alpha$- and $\beta$-hydroxy acids in increasing the physiological rate of epidermal cell renewal, while keeping a low skin-irritation level. In oral care cosmetics, it acts as a mucous membrane protectant (3). For its special water co-ordination capability, its solubilising power, polymer swelling capability, after-feel improvement in hair products, skin moisturization and elasticity enhancing properties, trimethylglycine provides unusual characteristics to many products intended for skin maintenance (4).(omitted)

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.4
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• pp.281-287
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• 2021

In this study, we analyzed the cosmetic applicability of extract from snow tea, native to Lijiang, Yunnan-province, China. After confirming the species as N. grossedentata through DNA analysis of Lijiang snow tea, experiments were conducted using representative tea, green tea, and a representative control group for each efficacy analysis. Both teas were extracted using 70% (v/v) ethanol aqueous solution. The polyphenol content in the Lijiang snow tea extract (gallic acid equivalent, 23.9 ± 3.2 mg/mL) was higher than that in green tea extract (16.4 ± 2.3 mg/mL). In contrast, the antioxidant (Radical scavenging, IC₅₀ 104 ㎍/mL), tyrosinase enzyme inhibitory (whitening agent, IC₅₀ 40.7 ㎍/mL), and Escherichia coli growth inhibitory (preservative) activities (IC₅₀ 2.85 mg/mL) were analyzed based on the solid content in the extract, and it was confirmed that the activities of Lijiang snow tea extract were superior to those of green tea extract (radical scavenging, IC₅₀ 234 ㎍/mL. It also showed similar efficacy to previously used active substances such as antioxidants (vitamin C, IC₅₀ 108 ㎍/mL), whitening agents (vitamin C, IC₅₀ 80㎍/mL), and preservatives (methylparaben, IC₅₀ 4.35 mg/mL). However, green tea was found to be better in collagenase inhibition activity (anti-wrinkle). Through this study, the cosmetic application potential of Lijiang snow tea is high.

• Journal of the Semiconductor & Display Technology
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• v.15 no.4
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• pp.51-60
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• 2016

Consumers who use mobile applications for their skin care are increasing due to increasing interest in skin care and smart phone use. A survey was conducted to select popular skin care mobile applications to be installed in the smart phone targeting 1,000 men and women in South Korea who are interested in their skin care. Questioned items included skin care awareness and recognition, skin care type, and the intention of using skin health care mobile services. The respondents thought the best skin as 'Flawless skin (52.3%)'. Also, 'Skin trouble' and 'Skin aging' were their major concerns. 47.1% of the respondents used mobile skin care applications, and 56.6% intended to try new mobile skin care services. The results on interesting field of skin care showed significant difference depending on gender, marital status, and annual average household income. Moreover, the results on effort made for skin care showed significant difference depending on age, gender, and marital status. They wanted the functions such as 'Review on cosmetic products by brand (23.8%)', 'Self skincare method (16.8%)', 'Continuous monitoring service (16.2%)', 'Information on cosmetic products (13.4%)'. The result of this study would be reliable as basic material for skincare mobile service area. Further studies could be focused on developing application in accordance with needs and how it should be applied.

• Journal of the Korean Home Economics Association
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• v.43 no.3 s.205
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• pp.1-10
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• 2005

The purpose of this study was to investigate the enforcement strategy for Consumer Service marketing of an e-Commerce shopping mall. An e-CRM for a Cosmetic e-Commerce shopping mall, Data Warehousing(DW) component, analysis of data mining of the DW, and web applications and strategies had to developed for marketing of consumer service satisfaction. The major findings were as follows: An RFM analysis was used for consumer classification, which is a fundamental process of e-CRM application. The components of the DW were web sales data and consumer data fields. The visual process of consumer segmentations (superior consumer class) for e-CRM solutions is presented. The association analysis algorithm of data mining to up-selling and cross-selling indicates an association rule. These e-CRM results apply web DB marketing and operating principles to a shopping mall. Therefore, the system applications of e-CRM to Consumer services indicate a marketing strategy for consumer-oriented management.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.2
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• pp.185-191
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• 2003

In this study, We measured transmittance and color change of various photochromic lens as a function of temperature(6, 12, $28^{\circ}C$), irradiation time of UVA lamp and the types of materials(plastic and glass) and distribution of photochromic ingredients(coated and bulk type). The coated-type photochromic lens showed higher saturated value than bulk-type lens without regard to temperature. And darkening rate of smoke color lenses were higher compare to brown lens in case of glass photochromic lens. All of photochromic lens passed ANSI Z80.3 regulation in transmittance and color independent of temperature. The saturated values of plastic photochromic lens excluded coated-type and glass photochromic lens were ranked as cosmetic use. The saturated value of coated-type. Tbr and TMs were general applications in $6^{\circ}C$ and $12^{\circ}C$, but cosmetic purpose in $28^{\circ}C$. The darkening rate was increased with decreasing temperature, whereas the fading rate became higher with increasing temperature.

• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.35-49
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• 2003

In this study, in an attempt to search for functional cosmetic ingredients from higher fungal, we have produced exopolysaccharides (GF-l, approximately carbohydrate 75％, protein 25％) and polysaccharide (GF-2) of mycelium extract, by submerged culture of Grifolafrondosa. For applications in anti-aging cosmetic field, we investigated the diverse biological activities. Antioxidant activity and inhibition of Matrixmetalloproteinases (MMPs) were investigated enzymatic assays by measuring the superoxide scavenging activity using xanthine-xanthine oxidase system and the proteolytic activity of MMPs using EnzChek Collagenase/Gelatinase kits, respectively. GF-l polysacchairde showed inhibition of superoxide radical by 90％ at a concentration of 0.2％ (w/v) and inhibition of collagenase by 45％ at 0.2％ (w/v). GF-2 polysaccharide of mycelium extract also exhibited good antioxidant activity. However, MMPs inhibition activity was relatively lower level compared to GF-l polysaccharides. The treatment of human dermal fibroblast (HDF) with GF-l and GF-2 polysaccharides increased the proliferation of fibroblast by approximately 23-25％ at a concentration of 0.5％ (w/v), also showed collagen synthesis increase in HDF by about 50％ at 0.5％ (w/v) compared to that of untreated control. We also report the moisturizing effects of polysaccharides in cosmetic products (O/W emulation) and its own ingredient, in vitro and in vivo. The GF-1 polysaccharide showed higher moisturizing ability than sodium hyaluronate, which is the most commonly used moisturizers ingredient. These results suggest the GF-l polysaccharide, protein-bound polysaccharide, may be used as an ingredient for new moisturizing and anti-aging cosmeceuticals.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.34 no.4
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• pp.245-258
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• 2008

We describe here how we can use microfluidic technologies for fabricating functional materials that could be potentially utilized in cosmetics; these include void structures, functional particulate materials, shell materials, and multi-layered colloids. We can obtain these functional materials as microfluidic approaches provide precise control over both outer dimensions and inner morphology of emulsion drops in picoliter-volume scales with high throughput. We have confirmed that this technique has a great potential to fabricate novel particles and capsules with a variety of chemical compositions as well as higher orders of layers. This microfluidic approach will allow us to develop a lot of new techniques that are useful for a variety of applications, including delivery systems, chemical separations, bio-sensing, actuators, and so on. We do believe that these new techniques will help cosmetic industry not only give rise advanced functional materials and systems but also widen its product categories.