• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권4호
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• pp.363-368
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• 2000

불화나트륨의 전신적인 투여가 백서골의 기계적, 조직학적인 특성에 미치는 영향을 알아보고자 0, 1, 5 및 50ppm의 불소를 6주간 투여한 다음 백서 대퇴골을 채취하여 대퇴골 전체의 압축 강도, 대퇴골 경부의 전단 강도를 만능압축시험기로 측정하고 대퇴골 횡단면 조직 슬라이드를 제작하여 피질골 및 골수강의 두께와 면적을 광학현미경과 image analyzer 등으로 측정한 결과는 다음과 같다. 1. 실험 6주간 불소 투여에 의한 백서 체중에 있어서 각 군간에 통계적으로 유의한 차이는 나타나지 않았다. 2. 6주간의 불소 투여시 대퇴골 전체의 압축강도는 대조군에 비해 1 및 5ppm 투여군에서 증가하다가 50ppm 투여군에서는 오히려 현저하게 감소하였다. 3. 대퇴골 경부의 전단 강도역시 대조군에 비해 1 및 5ppm군에서는 증가되다가 50ppm군에서는 감소되었으나 통계적으로 유의한 차이는 나타나지 않았다. 4. 피질골의 두께와 면적 역시 대조군에 비해 5ppm 투여군까지는 증가하다가 50ppm 투여군에서는 현저히 감소되었다. 5. 골수강의 두께와 면적은 대조군에 비해 불소투여군 모두에서 통계적으로 유의하게 증가되었다. 이상의 결과로 미루어 볼 때 상수도수불소화에 사용되는 1ppm의 불소 농도에서는 백서 대퇴골의 기계적인 압축강도가 증진되고 조직형태학적으로도 피질골의 두께가 증가됨으로 인하여 동일한 하중에서도 골의 파절에 대한 저항 능력을 향상시킬 수 있음을 확인하였다.

• 대한치과의사협회지
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• 제22권1호통권176호
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• pp.49-55
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• 1984

The objective of this study was to observe the healing of skin and mucosal grafts, comparing with the control sites. Six adult dogs were divided into two groups of three. Mucosal defects were created in all four quadrants, and the left side was used as a control. In the Group I animals, a split-thickness skin from the chest was grafted, and in the group II animals, a split-thickness mucosa from the buccal cheek was grafted into the mouth. Gross and microscopic examination was done at 3, 7, 14, 28, 42 days. The results were as follows. 1. Wound epithelization was accelerated in the supraperiosteal grafts. 2. After healing, the grafted skin was unnatural to the oral cavity, showing grayish-white color, hair, and sebaceous gland. But the mucosal grafts could not be discriminated from the adjacent mucosa. 3. the grafting on the cortical bone failed.

• 치과방사선
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• 제21권2호
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• pp.307-316
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• 1991

The purpose of this study is to improve the availabilities of radiographic technics as diagnostic method related to mandibular canal in dental clinic. For this study 12 dry mandibles were used and 12 orthopantomograms were taken for measuring the gonial angle and the angle of mandibular canal to inferior border of mandible. 12 sites located between the 1st premolar to the 3rd molar region of 3dry mandibles were selected randomly, for measuring the vertical image magnification rates on three films; intraoral film, orthopantomogram, and computed tomogram, respectively and the thickness of cortical bone, and for observing bucco-lingually and supero-inferiorly location of the mandibular canal. The acquired results were as follows: 1. The means of the gonial angle and the angle of mandibular canal to inferior border of mandible were 123.9° and 143.5° And the two angles of dry mandible in alveolar crest stage were greater than in alveolar socket stage. 2. The vertical image length on intraoral film by paralleling technic was magnified by 3.07% on the average, the length on orthopantomogram by 18.49%, and the length on computed tomogram by 0.27%. 3. Observation of the bucco-lingually positional relationship of the mandibular canal was impossible by occlusal projection with the cross section technic and intraoral standard projection with the Clack's rule, however, possible by computed tomogram. 4. The thickness of the cortical bone of mandible was thickest in inferior border, and thicker by 6.59% at buccal side than at lingual side.

• 대한수의학회지
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• 제41권3호
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• pp.395-400
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• 2001

The present study analyze the morphological aspects of the cerebrum of mice with prenatal exposure to high and low dose (0.5, 1, 2 Gy) of $\gamma$-radiation on gestation day 12 or 16. The animal were allowed to give birth and the offspring were sacrificed at postnatal days 28 for gross and microscopic examination of cerebrum. Their body weight, brain weight, brain length, brain width, cortical thickness and area of cingulum bundle were examined. The histological and planimetric analysis were performed observing coronal sections. The gross malfomation (microcephaly) and abnormality of cortical architecture were prominent after exposure to 2 Gy on day 12 of gestation. significant dose-related reductions in body weight, brain weight, brain size were found in all irradiated groups. A significant change was found in thickness of the cerebral cortex and area of the cingulum bundle in the groups exposed to 0.5 Gy or more. There was no difference a lamina patter of six layers in cerebral cortex between the control and irradiated groups, but cell packing density increased significantly in the group exposed to 1 Gy or more. These results suggested that dose as low as 0.5 Gy could cause a morphologically reduce change in developing mouse cerebrum and exposure on day 12 of gestation to $\gamma$-irradiation is a particularly sensitive phase in causing malformation and abnormality of central nerve system.

• Asian-Australasian Journal of Animal Sciences
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• 제16권1호
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• pp.50-56
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• 2003

An experiment was carried out to compare the body weight, shank length, rectal temperature, comb area, abdominal fat, blood parameters and bone traits of capon, slip and intact birds in Taiwan country chicken cockerels. One hundred and sixty-six Taiwan country chicken cockerels were randomly assigned to caponized or intact male groups. Caponized birds were surgically altered at 10 weeks old and raised to 28 weeks old. At 28 weeks of age, the capons were separated into capon and slip groups, depending on the atrophy of the comb and wattle in size. The results showed that body weight and shank length in slips were significantly (p<0.05) greater than in intact birds. Intact birds had the highest (p<0.05）feather scores and the lowest (p<0.05) rectal temperature. Compared with intact birds and slips, capons had a significantly (p<0.05) smaller comb area. Bone percentage, stress and cortical thickness, and bone and ash calcium content and plasma testosterone concentration, in intact birds were the highest (p<0.05) followed by slips and capons. However, intact birds had the lowest (p<0.05) plasma ionized calcium and phosphorus concentrations. Bone and ash manganese contents in capons were significantly (p<0.05)lower than those in others. These findings support the hypothesis that androgenic effects on secondary sexual characteristics are stronger than anabolic growth promoting response. Androgens can directly influence calcium fluxes in male chickens. Caponized caused a reduction in the bone percentage, stress, cortical thickness and bone calcium content.

• Journal of Oral Medicine and Pain
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• 제48권1호
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• pp.16-24
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• 2023

Purpose: To determine the effects of botulinum toxin (BoNT) injection into the human masseter muscle on the morphology of the mandibular condyle bone using cone-beam computed tomography (CBCT). Methods: Twenty volunteers were randomly assigned to one of two groups. Group I received a single BoNT injection; Group II received two injections, with the second being administered 4 months after the first. CBCT scans of both temporomandibular joints (TMJs) were performed before and 6 months after the first injection. Bony changes in the cortical layers of the condyle heads were evaluated and the long and short axes of both mandibular condyles were measured. The thickness at the thinnest part of glenoid fossa was also quantitatively measured. Results: There was no significant difference between pre- and post-injection CBCT images. Furthermore, no changes in the cortical layers of the condyle heads were observed among the subjects who exhibited mild degenerative TMJ changes. The quantitative measurements (long axis, short axis, and the thickness of thinnest part of glenoid fossa roof) did not differ significantly between pre- and post-injection except for the long axis in Group I. Conclusions: Within the limitations of this study, it appears that BoNT injections into human masseter muscles do not alter the morphology of the mandibular condyle bone in healthy adults.

• 한국임상수의학회지
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• 제18권2호
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• pp.116-123
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• 2001

This study was undertaken to find out the effect of Korean safflower seed powder on histopathological changes of cadmium toxicity in mice. Fifty BALB/c mice were divided into a control group(A) and four experimental groups(B, C, D, E) : group A received tap water and basal diet, group B received tap water and diet supplemented with 3% Korean safflower seed powder alone, group C received basal diet and 300 $\mu\textrm{g}$/g of cadmium, group D and E received basal diet supplemented with 3% and 10% Korean safflower seed powder and 300$\mu\textrm{g}$/g of cadmium respectively. Cadmium dissolved in tap water was used, and the Korean safflower seed powder were mixed with feed. All mice were dissected on the 56th day. Histopathological changes in liver, kidney, lung, cortical osseous tissue of femoral shaft, bone trabecular of femur, and epiphyseal cartilage plate of femur were observed. Group B showed no significant changes compared with the control group. But group C showed the unclearness of specific cells in liver, the loss of architecture and focal necrosis of hepatocyte, the glomerular swelling, degeneration and necrosis of convoluted tubules, desquamation and vacuolization of the greater part of the renal tubular epithelium, the marked congestion and thickness of the wall of alveolus in lung, slightly thinning of the cortical osseous tissue in femoral shaft, reduction of cancellous bone volume and marked narrowness of bone trabecular, marked thinning of epiphyseal cartilage plate and irregular arrangement of columnar structure of cartilage cells. On the other hand, Korean safflower seed powder-treated group showed a little convalescent changes and maintained their normal architectures in liner, kidney, lung, cortical osseous tissue of femoral shaft, bone trabecular of femur and epiphyseal cartilage plate of femur.

• 구강회복응용과학지
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• 제27권1호
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• pp.109-115
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• 2011

점차적으로 폭경이 증가하는 나사들을 이용하여 치조능확장술을 시행하고 임프란트를 식립하였다. 임상적으로 양호한 결과를 얻었으며 수술 중 협측 피질골판 골절은 발생하지 않았다. 임프란트 주변 결손부와 협측 피질골판 상방에 자가치아골이식재를 이식함으로써 부가적인 치조능 확장 효과와 동시에 협측 피질골판 흡수를 보상하였다. 치조능 폭경이 협소한 부위에 임프란트를 식립할 때 나사를 이용한 확장술은 성공적이고 예측 가능한 술식이며 자가치아골이식재는 치조능증대술과 골유도재생술을 위해 사용될 수 있다.

• 대한치과의사협회지
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• 제50권4호
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• pp.196-202
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• 2012

Radiographic diagnosis of periapical lesions is based on many factors, including anatomical limitations such as thickness of the cortical bone; positioning of the apical abscess to the cortical bone; and is complicated by proximity to other anatomical structures and neighboring teeth. With conventional radiographs, these structures are often superimposed. Dental CBCT with its associated geometric accuracy offers accurate visualizations of the complex relationships and boundaries between teeth, related anatomical features, and their associated pathology. Its images also provide us internal tooth morphology, periodontal ligament space, the presence or absence of periapicl lesions in association wi th critical anatomical structures and maxillary sinus involement. Using 3 D imaging makes it easier for clinicians to detect, diagnosis, and develop highly effective treatment plans. Now, 4 cases of periapical and periodontal pathosis with CBCT images are to be presented including periapical abscess, furcation involvement, periapical pathosis involving maxillary sinus, and osteomyelitis. CBCT analyze specific area of interest and provides the highly detailed anatomical information. It also facilitates earlier and more accurate diagnosis, and treatment planning decisions and more predictable outcome.

• Journal of Life Science
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• 제12권1호
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• pp.1-8
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• 2002

Antlers from deer species are alternative animal by-products. Due to the oriental trade, the velvet antler industry is rapidly emerging in North America. The unique biological property of antler wish a deciduous natural phenomenon offers the valuable model of biomedical research. Growing antlers showed different structures according to cell populations consisting of mesenchymes, chondroblasts, chondrocytes and osseous tissues from distal to proximal portions of main beam. Their structures were different from two tissues, cartilage and bone, in growing antlers. Zone of maturing ants calcifying chondrocytes referred as upper section was invaded by osteoblasts indicating the occurrence of endochondral ossification. The cartilaginous tissues were gradually replaced by osseous tissues downward. The bony tissues referred as the middle and base sections in this thesis contained spongy bone and cortical bone structure in the difference of the degree of mineralization antral the thickness of cortical bony in adjacent to outer velvet layer. In addition, the endocrinological regulators such as testosterone, prolactin, growth hormones and other growth factors are actively involved in the unique deciduous nature shown in the growth and development of antler.