• Title/Summary/Keyword: correlated parameters

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Estimation of Genetic Parameters for Calving Ease by Heifers and Cows Using Multi-trait Threshold Animal Models with Bayesian Approach

  • Lee, D.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.8
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    • pp.1085-1090
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    • 2002
  • Genetic parameters for birth weights (BWT), calving ease scores observed from calves born by heifers (CEH), and calving ease scores observed from calves born by cows (CEC) were estimated using Bayesian methodology with Gibbs sampling in different threshold animal models. Data consisted of 77,458 records for calving ease scores and birth weights in Gelbvieh cattle. Gibbs samplers were used to obtain the parameters of interest for the categorical traits in two univariate threshold animal models, a bivariate threshold animal model, and a three-trait linear-threshold animal model. Samples of heritabilities and genetic correlations were calculated from the posterior means of dispersion parameters. In a univariate threshold animal model with CEH (model 1), the posterior means of heritabilities for calving ease was 0.35 for direct genetic effects and 0.18 for maternal genetic effects. In the other univariate threshold model with CEC (model 2), the posterior means of heritabilities of CEC was 0.28 for direct genetic effects and 0.18 for maternal genetic effects. In a bivariate threshold model with CEH and CEC (model 3), heritability estimates were similar to those in unvariate threshold models. In this model, genetic correlation between heifer calving ease and cow calving ease was 0.89 and 0.87 for direct genetic effect and maternal genetic effects, respectively. In a three-trait animal model, which contained two categorical traits (CEH and CEC) and one continuous trait (BWT) (model 4), heritability estimates of CEH and CEC for direct (maternal) genetic effects were 0.40 (0.23) and 0.23 (0.13), respectively. In this model, genetic correlation estimates between CEH and CEC were 0.89 and 0.66 for direct genetic effects and maternal effects, respectively. These estimates were greater than estimates between BWT and CEH (0.82 and 0.34) or BWT and CEC (0.85 and 0.26). This result indicates that CEH and CEC should be high correlated rather than estimates between calving ease and birth weight. Genetic correlation estimates between direct genetic effects and maternal effects were -0.29, -0.31 and 0.15 for BWT, CEH and CEC, respectively. Correlation for permanent environmental effects between BWT and CEC was -0.83 in model 4. This study can provide genetic evaluation for calving ease with other continuous traits jointly with assuming that calving ease from first calving was a same trait to calving ease from later parities calving. Further researches for reliability of dispersion parameters would be needed even if the more correlated traits would be concerned in the model, the higher reliability could be obtained, especially on threshold model with property that categorical traits have little information.

Impact of COVID-19 spread on visit intervals and clinical parameters for patients with periodontitis in supportive periodontal therapy: a retrospective study

  • Mizuho Yamazaki-Takai;Yumi Saito;Shoichi Ito;Moe Ogihara-Takeda;Tsuyoshi Katsumata;Ryo Kobayashi;Shuta Nakagawa;Tomoko Nishino;Namiko Fukuoka;Kota Hosono;Mai Yamasaki;Yosuke Yamazaki;Yuto Tsuruya;Arisa Yamaguchi;Yorimasa Ogata
    • Journal of Periodontal and Implant Science
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    • v.54 no.2
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    • pp.75-84
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    • 2024
  • Purpose: This study investigated the relationship between the number of days that hospital visits were postponed and changes in clinical parameters due to the spread of coronavirus disease 2019 (COVID-19), after the Japanese government declared a state of emergency in April 2020. Methods: Regarding the status of postponement of appointments, we analyzed the patients who had visited the Nihon University Hospital at Matsudo for more than 1 year for supportive periodontal therapy (SPT) and classified them into low-, moderate- and high-risk subgroups according to the periodontal risk assessment (PRA). Clinical parameters for periodontal disease such as probing depth (PD), full-mouth bleeding score (FMBS), full-mouth plaque score, periodontal inflamed surface area (PISA), and periodontal epithelial surface area (PESA) were analyzed in 2 periods, from October 2019 to March 2020 and after April 2020. Correlation coefficients between days of deferral and the degree of changes in clinical parameters were calculated. Results: The mean age of the 749 patients was 67.56±10.85 years, and 63.82% were female. Out of 749 patients, 33.24% deferred their SPT appointments after April 2020. The average total of postponement days was 109.49±88.84. The number of postponement days was positively correlated with changes in average PD (rs=0.474) and PESA (rs=0.443) in the high-risk subgroup of FMBS, and average PD (rs=0.293) and PESA (rs=0.253) in the highrisk subgroup of tooth number (TN). Patients belonging to the high-risk subgroups for both FMBS and TN had a positive correlation between postponement days and PISA (rs=0.56). Conclusions: The findings, the spread of COVID-19 appears to have extended the visit interval for some SPT patients. Moreover, longer visit intervals were correlated with the worsening of some clinical parameters for SPT patients with high PRA.

Implications of Sarcopenia and Glucometabolism Parameters of Muscle Derived From Baseline and End-of-Treatment 18F-FDG PET/CT in Diffuse Large B-Cell Lymphoma

  • Xiaoyue Tan;Xiaolin Sun;Yang Chen;Fanghu Wang;Yuxiang Shang;Qing Zhang;Hui Yuan;Lei Jiang
    • Korean Journal of Radiology
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    • v.25 no.3
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    • pp.277-288
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    • 2024
  • Objective: We previously found that the incidence of sarcopenia increased with declining glucose metabolism of muscle in patients with treatment-naïve diffuse large B-cell lymphoma (DLBCL). This study aimed to investigate the relationship between sarcopenia and muscle glucometabolism using 18F-FDG PET/CT at baseline and end-of-treatment, analyze the changes in these parameters through treatment, and assess their prognostic values. Materials and Methods: The records of 103 patients with DLBCL (median 54 years [range, 21-76]; male:female, 50:53) were retrospectively reviewed. Skeletal muscle area at the third lumbar vertebral (L3) level was measured, and skeletal muscle index (SMI) was calculated to determine sarcopenia, defined as SMI < 44.77 cm2/m2 and < 32.50 cm2/m2 for male and female, respectively. Glucometabolic parameters of the psoas major muscle, including maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean), were measured at L3 as well. Their changes across treatment were also calculated as ΔSMI, ΔSUVmax, and ΔSUVmean; Δbody mass index was also calculated. Associations between SMI and the metabolic parameters were analyzed, and their associations with progression-free survival (PFS) and overall survival (OS) were identified. Results: The incidence of sarcopenia was 29.1% and 36.9% before and after treatment, respectively. SMI (P = 0.004) was lower, and sarcopenia was more frequent (P = 0.011) at end-of-treatment than at baseline. The SUVmax and SUVmean of muscle were lower (P < 0.001) in sarcopenia than in non-sarcopenia at both baseline and end-of-treatment. ΔSMI was positively correlated with ΔSUVmax of muscle (P = 0.022). Multivariable Cox regression analysis showed that sarcopenia at end-of-treatment was independently negatively associated with PFS (adjusted hazard ratio [95% confidence interval], 2.469 [1.022-5.965]), while sarcopenia at baseline was independently negatively associated with OS (5.051 [1.453-17.562]). Conclusion: Sarcopenic patients had lower muscle glucometabolism, and the muscular and metabolic changes across treatment were positively correlated. Sarcopenia at baseline and end-of-treatment was negatively associated with the prognosis of DLBCL.

An application to Multivariate Zero-Inflated Poisson Regression Model

  • Kim, Kyung-Moo
    • Journal of the Korean Data and Information Science Society
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    • v.14 no.2
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    • pp.177-186
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    • 2003
  • The Zero-Inflated Poisson regression is a model for count data with exess zeros. When the correlated response variables are intrested, we have to extend the univariate zero-inflated regression model to multivariate model. In this paper, we study and simulate the multivariate zero-inflated regression model. A real example was applied to this model. Regression parameters are estimated by using MLE's. We also compare the fitness of multivariate zero-inflated Poisson regression model with the decision tree model.

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SURFACE PHOTOMETRY OF BARRED GALAXIES.: I. MORPHOLOGY

  • Ann, Hong-Bae
    • Journal of The Korean Astronomical Society
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    • v.19 no.2
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    • pp.69-89
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    • 1986
  • The global morphology and geometric parameters of 39 barred galaxies are investigated, by using isophote map and isodensity tracings obtained from detailed surface photometry with the Kiso V-band plates. The observed results are as follows: i) There is no strong indication that the ratio of bar length to disk size is correlated with Hubble type, except that the largest bars appear in the SBb galaxies. ii) The mean value of axial ratios of bars is $2.0{\pm}0.4$ and there is a trend that early type galaxies have smaller axial ratios than late type galaxies. iii) About 15% of early type barred galaxies(Sb0-SBb) have triaxial bulges.

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Vibration Analysis and Experiments of a Chip Mounting Device (칩마운터의 진동 해석 및 실험 분석)

  • 고병식;이승엽
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2002.05a
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    • pp.1039-1042
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    • 2002
  • SMD(Surface Mounting Device) which mounts electronic components as IC-Chips on PCB automatically, produces a large dynamic force and vibration. The unwanted vibrations in SMD degrade the performance of the precision device and it is the major obstacle to limit its speed for mounting. This study investigated the vibration analysis of a typical SMD to predict the natural frequencies and mode shapes. To validate the finite element analysis of SMD, the FE result was compared with that of ODS measurements. It was shown that the predicted results were well correlated with the experimental modal parameters.

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Parametric Analysis of the Solar Radiation Pressure Model for Precision GPS Orbit Determination

  • Bae, Tae-Suk
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.35 no.1
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    • pp.55-62
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    • 2017
  • The SRP (Solar Radiation Pressure) model has always been an issue in the dynamic GPS (Global Positioning System) orbit determination. The widely used CODE (Center for Orbit Determination in Europe) model and its variants have nine parameters to estimate the solar radiation pressure from the Sun and to absorb the remaining forces. However, these parameters show a very high correlation with each other and, therefore, only several of them are estimated at most of the IGS (International GNSS Service) analysis centers. In this study, we attempted to numerically verify the correlation between the parameters. For this purpose, a bi-directional, multi-step numerical integrator was developed. The correlation between the SRP parameters was analyzed in terms of post-fit residuals of the orbit. The integrated orbit was fitted to the IGS final orbit as external observations. On top of the parametric analysis of the SRP parameters, we also verified the capabilities of orbit prediction at later time epochs. As a secondary criterion for orbit quality, the positional discontinuity of the daily arcs was also analyzed. The resulting post-fit RMSE (Root-Mean-Squared Error) shows a level of 4.8 mm on average and there is no significant difference between block types. Since the once-per-revolution parameters in the Y-axis are highly correlated with those in the B-axis, the periodic terms in the D- and Y-axis are constrained to zero in order to resolve the correlations. The 6-hr predicted orbit based on the previous day yields about 3 cm or less compared to the IGS final orbit for a week, and reaches up to 6 cm for 24 hours (except for one day). The mean positional discontinuity at the boundary of two 1-day arcs is on the level of 1.4 cm for all non-eclipsing satellites. The developed orbit integrator shows a high performance in statistics of RMSE and positional discontinuity, as well as the separations of the dynamic parameters. In further research, additional verification of the reference frame for the estimated orbit using SLR is necessary to confirm the consistency of the orbit frames.

Validation of a simple binary scoring system for assessment of welfare measures of 10-day-old commercial broilers and their correlation with environmental parameters

  • Kumari, Priyanka;Choi, Hong-Lim;Metali, Shamira Hazi;Yussof, Siti Anisah Hazi;Han, Jiwoon
    • Journal of Animal Science and Technology
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    • v.57 no.3
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    • pp.9.1-9.5
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    • 2015
  • Background: A simple binary scoring system (SBSS) was developed and used to assess the welfare measures of commercial broiler chickens in South Korea. We also correlated welfare measures with environmental parameters of broiler house. Our measures of welfare included lameness, hock burn (HB) and foot pad dermatitis (FPD), whilst environmental parameters included air temperature, relative humidity, air speed, light intensity, air quality (in particular carbon dioxide ($CO_2$) and ammonia ($NH_3$) concentrations) and airborne microbes. Results: The effect of environmental parameters on welfare measures was apparent even on 10-day-old broilers. A non-parametric correlation analysis revealed significant correlations between environmental parameters and welfare measures. The key environmental parameters were relative humidity and light intensity. The results indicate that there is a need for proper control of environmental conditions on poultry farms, which could reduce health problems and subsequently reduce disease and mortality. Conclusions: In conclusion, the simplicity of SBSS makes it preferable over more complex scoring systems and allows a farmer to more easily assess the welfare measures on their own farm.

A Comparison of Parameters of Acoustic Vowel Space in Patients with Parkinson's Disease (파킨슨병 환자의 음향 모음 공간 파라미터 비교)

  • Kang, Young-Ae;Yoon, Kyu-Chul;Lee, Hak-Seung;Seong, Cheol-Jae
    • Phonetics and Speech Sciences
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    • v.2 no.4
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    • pp.185-192
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    • 2010
  • The acoustic vowel space has been used as an acoustic parameter in dysarthric speech. The aim of this work was to examine mathematical formulae for acoustic vowel space and to apply these to Korean speakers with idiopathic Parkinson's disease(IPD). Five acoustic parameters were chosen from earlier works and one new parameter was proposed, the pentagonal vowel space. The six parameters included triangular vowel space (3 area), irregular quadrilateral vowel space (4 area), irregular pentagonal vowel space (5 area), vowel articulatory index (VAI), formant centralization ratio (FCR) and F2i/F1u ratio (F2 ratio). An experimental group of 32 IPD patients(male:female=16:16) and a control group of twenty healthy people (male:female=8:12) participated in the study and repeated vowels (/a-i-u-e-o/) three times. A correlation analysis was performed among the six parameters, 2-way ANOVA was done with gender and groups as independent factors, and an independent sample t-test was conducted between the male and the female group as post hoc comparison. All parameters were highly correlated with each other and only the FCR showed a high negative correlation with the others. The results of ANOVA showed a significant difference in F2 ratio, 3 area, 4 area and 5 area between gender and in 4 area and 5 area between groups. For the male members of the two groups, significant statistical differences were found in all parameters whereas no such differences were found for the female members. These findings indicated that the vowel space of the female group was wider than the vowel space of the male group. These differences may have been caused by gender-specific speech styles rather than by patho-physiological mechanisms. We also claim that the pentagonal vowel space is better than the other vowel spaces at representing the disordered speech in natural speech situations.

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Sine sweep effect on specimen modal parameters characterization

  • Roy, Nicolas;Violin, Maxime;Cavro, Etienne
    • Advances in aircraft and spacecraft science
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    • v.5 no.2
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    • pp.187-204
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    • 2018
  • The sine sweep base excitation test campaign is a major milestone in the process of mechanical qualification of space structures. The objectives of these vibration tests are to qualify the specimen with respect to the dynamic environment induced by the launcher and to demonstrate that the spacecraft FE model is sufficiently well correlated with the test specimen. Dynamic qualification constraints lead to performing base excitation sine tests using a sine sweep over a prescribed frequency range such that at each frequency the response levels at all accelerometers, load cells and strain gages is the same as the steady state response. However, in practice steady state conditions are not always satisfied. If the sweep rate is too high the response levels will be affected by the presence of transients which in turn will have a direct effect on the estimation of modal parameters. A study funded by ESA and AIRBUS D&S was recently carried out in order to investigate the influence of sine sweep rates in actual test conditions. This paper presents the results of this study along with recommendations concerning the choice of methods.