• Title/Summary/Keyword: core log

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An Analysis of the Behavior of Rock Slope with Excavation-Induced Tension Cracks Located in DongHae Highway Construction Site (개착과정에서 인장균열이 발생된 동해고속도로 건설현장 암반사면의 거동 해석)

  • 조태진;이창영;고기성
    • Journal of the Korean Geotechnical Society
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    • v.20 no.8
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    • pp.15-27
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    • 2004
  • Sliding aspects of rock slope, where large-scaled tension cracks are induced during preliminary excavation, have been analyzed. Structure of rock mass is investigated by performing the electrical resistivity survey and the orientations and positions of discontinuities are measured from DOM-drilled core log. Geological evidence far primary failure movement has been detected and clay minerals which possess swelling properties are identified through XRD analysis. Slope stability is examined by considering the orientations of discontinuities and their trace distributions on the cut-face and neighboring natural slope surface. Both orientations and positions of failure-invoking discontinuity planes, traces of which are exposed within the anticipated sliding region, are concerned fur analyzing the preferred sliding directions. Regional sliding vectors are assessed based on the relative positions of potential sliding planes in the boreholes and the general trend of anticipated failure movement of rock slope is also investigated.

Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Platinum-based Chemotherapy Response of Advanced Non-small Cell Lung Cancers in a Chinese Population

  • Xu, Jia-Li;Wang, Zhen-Wu;Hu, Ling-Min;Yin, Zhi-Qiang;Huang, Ming-De;Hu, Zhi-Bin;Shen, Hong-Bing;Shu, Yong-Qian
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2157-2162
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    • 2012
  • Objective: The PI3K/PTEN/AKT/mTOR signaling pathway has been implicated in resistance to cisplatin. In the current study, we determined whether common genetic variations in this pathway are associated with platinum-based chemotherapy response and clinical outcome in advanced non-small cell lung cancer (NSCLC) patients. Methods: Seven common single nucleotide polymorphisms (SNPs) in core genes of this pathway were genotyped in 199 patients and analyzed for associations with chemotherapy response, progression-free survival (PFS) and overall survival (OS). Results: Logistic regression analysis revealed an association between AKT1 rs2494752 and response to treatment. Patients carrying heterozygous AG had an increased risk of disease progression after two cycles of platinum-based chemotherapy compared to those with AA genotype (Adjusted odds ratio (OR)=2.18, 95% confidence interval (CI): 1.00-4.77, which remained significant in the stratified analyses). However, log-rank test and cox regression detected no association between these polymorphisms in the PI3K pathway genes and survival in advanced NSCLC patients. Conclusions: Our findings suggest that genetic variants in the PI3K/PTEN/AKT/mTOR pathway may predict platinum-based chemotherapy response in advanced NSCLC patients in a Chinese population.

A Form Clustering Algorithm for Web-based Application Reengineering (웹 응용 재구성을 위한 폼 클러스터링 알고리즘)

  • 최상수;박학수;이강수
    • The Journal of Society for e-Business Studies
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    • v.8 no.2
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    • pp.77-98
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    • 2003
  • A web-based information system, that is a dominant type of information systems, suffers from the "web crisis" in development and maintenance of the system. To cope with the problem, a technology of software clustering to web-based application, which is one of web engineering, is strongly needed. In this paper, we propose a Form Clustering Algorithm along with an application example, which are used for internal-system reengineering to web-based information system. A Form Clustering Algorithm focuses on Page-model which is the feature of the web among the various web-based information system's structural model. Specially, we applying distance matrix to navigation model of graph form for easily analyzing, and web log analysis for identifying core function object that have a highly loading. Also, we create web software structure that can be used to maximize reusability and assign hardware effectively through 2-phase clustering step. Form Clustering Algorithm might be used at web-based information system development and maintenance for reusable web component development and hardware assignment, respectively.

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Association of Plasma Osteoprotegerin with Adiponectin and Difference according to Obesity in Men with Metabolic Syndrome (대사증후군 남성에서의 혈중 Osteoprotegerin의 아디포넥틴과의 상관성과 비만도에 따른 차이)

  • Na, Woo-Ri;Sohn, Cheong-Min
    • Korean Journal of Community Nutrition
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    • v.16 no.6
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    • pp.762-770
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    • 2011
  • Osteoprotegerin (OPG) plays a core role in bone reformation by antagonizing the effect of receptor activator of nuclear factor ${\kappa}$-B ligand (RANKL), and mediates vascular calcification in cardiovascular disease patients. Thus, we aimed to examine the relationship between serum OPG levels and cardiovascular factors and inflammatory markers in metabolic syndrome patients (MS). This cross-sectional study included 96 men who visited the diet clinic between May and July 2011. Patients were classified into 2 groups based on NCEP-ATP guidelines: normal and with MS (n = 50 and 46, respectively). Physical measurements, biochemical assay were measured. Serum OPG and IL-6, diponectin and hs-CRP were assessed. MS were aged $50.02{\pm}10.85$ years, and normal patients $52.07{\pm}9.56$ years, with no significant differences. Significant differences were not observed in BMI between the 2 groups. Moreover, significant differences were not observed in serum OPG, however, the serum OPG level ($4.41{\pm}1.86pmol/L$) differed significantly between an overweight MS (BMI > 25) and normal patients. OPG was correlated to age (r = 0.410, p = 0.000), HDL-cholesterol (r = 0.209, p = 0.015), and log adiponectin (r = 0.175, p = 0.042). Multiple regression analyses using the enter method showed that age (${\beta}$ = 0.412, p = 0.000) and BMI (${\beta}$ = 0.265, p = 0.000) considerably affected OPG. In conclusion, out study showed that serum OPG levels are correlated with cardiovascular risk factors, such as BMI, HDL-cholesterol and adiponectin in MS and adiponectin, suggesting that serum OPG has potential as a cardiovascular disease indicator and predictor.

Role of eptC in Biofilm Formation by Campylobacter jejuni NCTC11168 on Polystyrene and Glass Surfaces

  • Lim, Eun Seob;Kim, Joo-Sung
    • Journal of Microbiology and Biotechnology
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    • v.27 no.9
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    • pp.1609-1616
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    • 2017
  • The complex roles of cell surface modification in the biofilm formation of Campylobacter jejuni, a major cause of worldwide foodborne diarrheal disease, are poorly understood. In a screen of mutants from random transposon mutagenesis, an insertional mutation in the eptC gene (cj0256) resulted in a significant decrease in C. jejuni NCTC11168 biofilm formation (<20%) on major food contact surfaces, such as polystyrene and borosilicate glass, when compared with wild-type cells (p < 0.05). In C. jejuni strain 81-176, the protein encoded by eptC modified cell surface structures, such as lipid A, the inner core of lipooligosaccharide, and the flagellar rod protein (FlgG), by attaching phosphoethanolamine. To assess the role of eptC in C. jejuni NCTC11168, adherence and motility tests were performed. In adhesion assays with glass surfaces, the eptC mutant exhibited a $0.77log\;CFU/cm^2$ decrease in adherence compared with wild-type cells during the initial 2 h of the assay (p < 0.05). These results support the hypothesis that the modification of cell surface structures by eptC affects the initial adherence in biofilm formation of C. jejuni NCTC11168. In motility tests, the eptC mutant demonstrated reduced motility when compared with wild-type cells, but wild-type cells with the transposon inserted in a gene irrelevant to biofilm formation (cj1111c) also exhibited decreased motility to a similar extent as the eptC mutant. This suggests that although eptC affects motility, it does not significantly affect biofilm formation. This study demonstrates that eptC is essential for initial adherence, and plays a significant role in the biofilm formation of C. jejuni NCTC11168.

Coupled Hydrological-mechanical Behavior Induced by CO2 Injection into the Saline Aquifer of CO2CRC Otway Project (호주 오트웨이 프로젝트 염수층 내 CO2 주입에 따른 수리-역학적 연계거동 분석)

  • Park, Jung-Wook;Shinn, Young Jae;Rutqvist, Jonny;Cheon, Dae-Sung;Park, Eui-Seob
    • Tunnel and Underground Space
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    • v.26 no.3
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    • pp.166-180
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    • 2016
  • The present study numerically simulated the CO2 injection into the saline aquifer of CO2CRC Otway pilot project and the resulting hydrological-mechanical coupled process in the storage site by TOUGH-FLAC simulator. A three-dimensional numerical model was generated using the stochastic geological model which was established based on well log and core data. It was estimated that the CO2 injection of 30,000t over a period of 200 days increased the pressure near the injection point by 0.5 MPa at the most. The pressure increased rapidly and tended to approach a certain value at an early stage of the injection. The hydrological and mechanical behavior observed from the CO2 flow, effective stress change and stress-strength ratio revealed that the CO2 injection into the saline aquifer under the given condition would not have significant effects on the mechanical safety of the storage site and the hydrological state around the adjacent fault.

Identification of Dominant Cause of Cut-Slope Collapse and Monitoring of Reinforced Slope Behavior (개착사면의 붕락요인 분석 및 보강거동 계측)

  • Cho, Tae-Chin;Lee, Sang-Bae;Lee, Guen-Ho;Hwang, Taik-Jean;Kang, Pil-Gue;Won, Byung-Nam
    • Tunnel and Underground Space
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    • v.21 no.1
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    • pp.20-32
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    • 2011
  • Failure aspects of cut-slope, which induce the sequential collapses during the excavation stage, have been analyzed. Slope rock structures are investigated by examining the orientations and positions of discontinuity planes calculated based on the BIPS image inside the boreholes. Drilled core log has been also used to identify the structural defects. Clay minerals of swelling potentials are detected through XRD analysis. Numerical analysis for slope stability has been performed by utilizing the joint shear strength acquired from the direct joint shear test. Cut-slope collapse characteristics have been studied by investigating the posture of failure-prawn joint planes and the stability of tetrahedral blocks of different sizes. Cross-section analysis has been also performed to analyze the cut-slope behavior and to estimate the amount of reinforcement required to secure the stability of cut-slope. Behavior of reinforced cut-slope is also investigated by analyzing the slope monitoring data.

The Effect of Customer Satisfaction on Corporate Credit Ratings (고객만족이 기업의 신용평가에 미치는 영향)

  • Jeon, In-soo;Chun, Myung-hoon;Yu, Jung-su
    • Asia Marketing Journal
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    • v.14 no.1
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    • pp.1-24
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    • 2012
  • Nowadays, customer satisfaction has been one of company's major objectives, and the index to measure and communicate customer satisfaction has been generally accepted among business practices. The major issues of CSI(customer satisfaction index) are three questions, as follows: (a)what level of customer satisfaction is tolerable, (b)whether customer satisfaction and company performance has positive causality, and (c)what to do to improve customer satisfaction. Among these, the second issue is recently attracting academic research in several perspectives. On this study, the second issue will be addressed. Many researchers including Anderson have regarded customer satisfaction as core competencies, such as brand equity, customer equity. They want to verify following causality "customer satisfaction → market performance(market share, sales growth rate) → financial performance(operating margin, profitability) → corporate value performance(stock price, credit ratings)" based on the process model of marketing performance. On the other hand, Insoo Jeon and Aeju Jeong(2009) verified sequential causality based on the process model by the domestic data. According to the rejection of several hypotheses, they suggested the balance model of marketing performance as an alternative. The objective of this study, based on the existing process model, is to examine the causal relationship between customer satisfaction and corporate value performance. Anderson and Mansi(2009) proved the relationship between ACSI(American Customer Satisfaction Index) and credit ratings using 2,574 samples from 1994 to 2004 on the assumption that credit rating could be an indicator of a corporate value performance. The similar study(Sangwoon Yoon, 2010) was processed in Korean data, but it didn't confirm the relationship between KCSI(Korean CSI) and credit ratings, unlike the results of Anderson and Mansi(2009). The summary of these studies is in the Table 1. Two studies analyzing the relationship between customer satisfaction and credit ratings weren't consistent results. So, in this study we are to test the conflicting results of the relationship between customer satisfaction and credit ratings based on the research model considering Korean credit ratings. To prove the hypothesis, we suggest the research model as follows. Two important features of this model are the inclusion of important variables in the existing Korean credit rating system and government support. To control their influences on credit ratings, we included three important variables of Korean credit rating system and government support, in case of financial institutions including banks. ROA, ER, TA, these three variables are chosen among various kinds of financial indicators since they are the most frequent variables in many previous studies. The results of the research model are relatively favorable : R2, F-value and p-value is .631, 233.15 and .000 respectively. Thus, the explanatory power of the research model as a whole is good and the model is statistically significant. The research model has good explanatory power, the regression coefficients of the KCSI is .096 as positive(+) and t-value and p-value is 2.220 and .0135 respectively. As a results, we can say the hypothesis is supported. Meanwhile, all other explanatory variables including ROA, ER, log(TA), GS_DV are identified as significant and each variables has a positive(+) relationship with CRS. In particular, the t-value of log(TA) is 23.557 and log(TA) as an explanatory variables of the corporate credit ratings shows very high level of statistical significance. Considering interrelationship between financial indicators such as ROA, ER which include total asset in their formula, we can expect multicollinearity problem. But indicators like VIF and tolerance limits that shows whether multicollinearity exists or not, say that there is no statistically significant multicollinearity in all the explanatory variables. KCSI, the main subject of this study, is a statistically significant level even though the standardized regression coefficients and t-value of KCSI is .055 and 2.220 respectively and a relatively low level among explanatory variables. Considering that we chose other explanatory variables based on the level of explanatory power out of many indicators in the previous studies, KCSI is validated as one of the most significant explanatory variables for credit rating score. And this result can provide new insights on the determinants of credit ratings. However, KCSI has relatively lower impact than main financial indicators like log(TA), ER. Therefore, KCSI is one of the determinants of credit ratings, but don't have an exceedingly significant influence. In addition, this study found that customer satisfaction had more meaningful impact on corporations of small asset size than those of big asset size, and on service companies than manufacturers. The findings of this study is consistent with Anderson and Mansi(2009), but different from Sangwoon Yoon(2010). Although research model of this study is a bit different from Anderson and Mansi(2009), we can conclude that customer satisfaction has a significant influence on company's credit ratings either Korea or the United State. In addition, this paper found that customer satisfaction had more meaningful impact on corporations of small asset size than those of big asset size and on service companies than manufacturers. Until now there are a few of researches about the relationship between customer satisfaction and various business performance, some of which were supported, some weren't. The contribution of this study is that credit rating is applied as a corporate value performance in addition to stock price. It is somewhat important, because credit ratings determine the cost of debt. But so far it doesn't get attention of marketing researches. Based on this study, we can say that customer satisfaction is partially related to all indicators of corporate business performances. Practical meanings for customer satisfaction department are that it needs to actively invest in the customer satisfaction, because active investment also contributes to higher credit ratings and other business performances. A suggestion for credit evaluators is that they need to design new credit rating model which reflect qualitative customer satisfaction as well as existing variables like ROA, ER, TA.

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School Experiences and the Next Gate Path : An analysis of Univ. Student activity log (대학생의 학창경험이 사회 진출에 미치는 영향: 대학생활 활동 로그분석을 중심으로)

  • YI, EUNJU;Park, Do-Hyung
    • Journal of Intelligence and Information Systems
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    • v.26 no.4
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    • pp.149-171
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    • 2020
  • The period at university is to make decision about getting an actual job. As our society develops rapidly and highly, jobs are diversified, subdivided, and specialized, and students' job preparation period is also getting longer and longer. This study analyzed the log data of college students to see how the various activities that college students experience inside and outside of school might have influences on employment. For this experiment, students' various activities were systematically classified, recorded as an activity data and were divided into six core competencies (Job reinforcement competency, Leadership & teamwork competency, Globalization competency, Organizational commitment competency, Job exploration competency, and Autonomous implementation competency). The effect of the six competency levels on the employment status (employed group, unemployed group) was analyzed. As a result of the analysis, it was confirmed that the difference in level between the employed group and the unemployed group was significant for all of the six competencies, so it was possible to infer that the activities at the school are significant for employment. Next, in order to analyze the impact of the six competencies on the qualitative performance of employment, we had ANOVA analysis after dividing the each competency level into 2 groups (low and high group), and creating 6 groups by the range of first annual salary. Students with high levels of globalization capability, job search capability, and autonomous implementation capability were also found to belong to a higher annual salary group. The theoretical contributions of this study are as follows. First, it connects the competencies that can be extracted from the school experience with the competencies in the Human Resource Management field and adds job search competencies and autonomous implementation competencies which are required for university students to have their own successful career & life. Second, we have conducted this analysis with the competency data measured form actual activity and result data collected from the interview and research. Third, it analyzed not only quantitative performance (employment rate) but also qualitative performance (annual salary level). The practical use of this study is as follows. First, it can be a guide when establishing career development plans for college students. It is necessary to prepare for a job that can express one's strengths based on an analysis of the world of work and job, rather than having a no-strategy, unbalanced, or accumulating excessive specifications competition. Second, the person in charge of experience design for college students, at an organizations such as schools, businesses, local governments, and governments, can refer to the six competencies suggested in this study to for the user-useful experiences design that may motivate more participation. By doing so, one event may bring mutual benefits for both event designers and students. Third, in the era of digital transformation, the government's policy manager who envisions the balanced development of the country can make a policy in the direction of achieving the curiosity and energy of college students together with the balanced development of the country. A lot of manpower is required to start up novel platform services that have not existed before or to digitize existing analog products, services and corporate culture. The activities of current digital-generation-college-students are not only catalysts in all industries, but also for very benefit and necessary for college students by themselves for their own successful career development.

The Study for Analysis of Website in Chinese Area Studies(This Topic is about CSF : China Specialist Forum) (중국 지역학연구에 이용되는 웹사이트 활용실태분석에 관한 연구(CSF : China Specialist Forum 을 중심으로))

  • Chong, Da-Song;Kang, Jun-Young
    • Journal of Digital Contents Society
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    • v.14 no.4
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    • pp.565-571
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    • 2013
  • We need to study China, the country that's improving constantly, in perspective of economic, political, social integration, and area studies with expertise in some perspective. If we expand the range of view to studies at industry research, national organization, and academia, exact information and diversity with professional research information portal site is at the core of the region. Specialized information portal site in China through an analysis of Chinese studies at the research analyzes the usage of the content. Through the main advantage of the status and content attributes of a site visitor analysis, it has shown a relatively high user loyalty through last 10 years operating as a single topic of professional information website. Through the CSF, the national level with expertise in design construction information portal site can be used as a more efficient way to build the foundation planning. Furthermore, through the effective use of information in China, the two countries, South Korea and China laid the foundation for the economic development of area studies which is expected to contribute to the establishment of information systems.