• Herbal Formula Science
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• v.30 no.3
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• pp.145-154
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• 2022

Objective : This study aims to study core herbs and formulas in Internal medicine on Spleen system, to enhance efficiency in teaching Internal medicine on Spleen system, Herbalogy, Formula science, and to increase integration of the courses. Methods : Frequency notion, which was generally used in previous studies, was used in this study along with network analysis. Results : Frequently used herbs, herbs with high centrality, frequently combined herbs and core formula were found in this study. The herb with the highest frequency and centrality was 'Citri Unshius Pericarpium', and 'Atractylodis Rhizoma Alba - Citri Unshius Pericarpium' was the most frequent herb combination. The results of network analysis showed a total of 5 herbal communities of combination. Conclusion : Core herbs were found based on the frequency notion, which is a traditional analysis method. Also, core herbs, herbal combinations, formulas that can that may be overlooked when using frequency notions were found by using network analysis. The results may lead to enhancing efficiency in the education of Internal medicine on Spleen system, Herbalogy, Formula science courses and the integration of courses.

• Journal of Korean Medical classics
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• v.23 no.1
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• pp.133-142
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• 2010

Preconditions for the separation of prescribing and dispensing medicinal herbs in Traditional Korean Medicine are classification of medicinal herbs for general public and special medical uses, establishment of national medicinal herb distribution company of governmental base, restriction in purchase of medicinal herbs for special medical use, partnership between doctors and pharmacists of Traditional Korean Medicine, and coverage of herbal medicine-based medication in national health insurance, etc. The number of Traditional Korean Medicine Pharmacists which was born during 'the herbal medicine conflict' initiated in 1993, goes over 1,000 and will increase by 120 annually. The number of Traditional Korean Medical Doctors is over 17,000 and increases by 850 annually. So in order to engage partnership between two groups, the government have to arrange the number of outputs of each group. Standardization and classification of diagnosis and diseases in Traditional Korean Medicine is a matter of course in the separation of prescribing and dispensing medicinal herbs. Related societies and academies need to do researches with governmental fund first. After these works, we can launch a task force team for implementation of process for the separation of prescribing and dispensing medicinal herbs in Traditional Korean Medicine properly. Entering the national health insurance system for full coverage of Korean Medicine care service will be essential for the patients. Implementation the separation of prescribing and dispensing medicinal herbs in Traditional Korean Medicine would be the core of health insurance coverage for medication.

• Journal of the Korean earth science society
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• v.26 no.3
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• pp.276-282
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• 2005

The Quaternary palynoflora from Cheongsu core, drilled on the western part of the Jeju Island, consists mainly of deciduous broad-leaved angiosperms and herbs. Dominant taxa are Pinaceae, Alnus, Castanea/Castanopsis, Ulmus/Zelkova, Chenopodiaceae and Compositae. Based on palynofloral composition, two palynostratigraphic zones are recognized. Zone I is characterized by a predominance of Alnus and Chenopodiaceae, and by the abundance of herbs. Zone II is dominated by conifers and deciduous broad-leaved angiosperms, including Abies, Taxodiaceae-Cupressaceae-Taxaceae, Ulmus/Zelkova and Gramineae. The Cheongsu palynoflora can be correlated with Alnipollenites(Alnus)-Chenopodipollis(Chenopodiaceae)-Compositae Assemblage Zone of the East China Sea and is assigned to the Pleistocene in age. Ecology of main taxa and comparison with the present vegetation of Korea suggest a cool temperate climate and a low relief in the Jeju Island during the deposition of the Cheongsu core sediments.

• Culinary science and hospitality research
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• v.7 no.3
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• pp.163-178
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• 2001

The purpose of this study is analysis of fusion cuisine recipe a gathering datum and informations for development of the fusion cuisine. The fusion cuisine is a new creative cuisine that come from a mixing between different cuisine recipe especially eastern cuisine wi th western cuisine. The fusion food is becoming a world popular food since 1980's. In Korea, the fusion food is favorite food is needed for development of the fusion cuisine, and we are able to get the datum and informations from mass media such as cuisine journals, newspapers and internet web site. Results of the analysis are as follows : 1. The fusion cuisine that core stuff is the grain have features that make a use of a spice and fat such as butter and olive oil. Boiling is used most frequently as a way of cooking among the grain centred fusion cuisine. Spagetti is used very after as a stuff for the fusion food. 2. The fusion cuisine that core stuff is meat make use of unusual meat such as the pigeons and spicery, and its popular cooking way is a baking. 3, The fusion cuisine that core stuff is a fish make use of herbs and alchole to get rid of a fishy smell, and various sauces are used for promoting taste and styling. 4. The fusion cuisine that core stuff is fruit and vegetables make use of boiling as cooking ways most frequently, but in the case that cook try to keep nutritive qualities, baking is used most frequently. 5. In beverage centred fusion cuisine, mixing of alchole with juice is most popular, its taste and color is unusually gorgeous.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.4
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• pp.35-44
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• 2012

Objectives : This study was aimed to evaluate the treatment effect of psoriasis patient using pyretotherapy. Methods : The clinical study was performed using retrospective observational research method. Treatment method was pyretotherapy that optimized core temperature through herbs therapy, food therapy, excercise and life style change. In other aspects, pyretotherapy is skin cure therapy that rise core temperature, down skin temperature and open sweat gland. Results : 1. 40s years showed the most coming of clinic in the distribution of age of psoriasis patient. 2. Board type showed the most number in the classification of psoriasis. 3. Pyretotherapy was very effective results in psoriasis patient treatment. 4. Pyretotherapy showed effects of rising axillary temperature and moving facial high skin temperature toward abdominal portion. Conclusions : The author is able to say that it is possible for pyretotherapy to become new skin therapy for many skin disease, especially psoriasis.

• Journal of Ginseng Research
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• v.47 no.4
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• pp.493-505
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• 2023

In recent years, an increasing number of reports have explored the wound healing mechanism of these two traditional Chinese herbal medicines- Panax ginseng and Panax notoginseng, but there is no systematic research on the related core functions and different mechanisms in the treatment of wound healing up to now. Based on network pharmacology and meta-analysis, the present work aimed to comprehensively review the commonality and diversity of P. ginseng and P. notoginseng in wound healing. In this study, a wound healing-related "ingredients-targets" network of two herbs was constructed. Thereafter, meta-analysis of the multiple target lists by Metascape showed that these two medicines significantly regulated blood vessel development, responses to cytokines and growth factors and oxygen levels, cell death, cell proliferation and differentiation, and cell adhesion. To better understand the discrepancy between these two herbs, it was found that common signaling pathways including Rap1, PI3K/AKT, MAPK, HIF-1 and Focal adhesion regulated the functions listed above. In parallel, the different pathways including renin-angiotensin system, RNA transport and circadian rhythm, autophagy, and the different metabolic pathways may also explained the discrepancies in the regulation of the above-mentioned functions, consistent with the Traditional Chinese Medicine theory about the effects of P. ginseng and P. notoginseng.

• The Journal of the Korea Contents Association
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• v.16 no.6
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• pp.260-269
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• 2016

With the development of genomics, wearable device and IT/NT, a vast amount of bio-medical data are generated recently. Also, healthcare industries based on big-data are booming and big-data technology based on bio-medical data is rising rapidly as a core technology for improving the national health and aged society. Also, oriental medicine research is focused with modern research technology and validate it's various biochemical effect by combining with molecular biology technology. However there are few searching system for finding biochemical mechanism which is related to major compounds in oriental medicine. Therefore, in this paper, we collected papers related with medical herbs from PubMed and constructed a medical herbs database to store and manage chemical, gene/protein and biological interaction information extracted by a literature analysis on the papers. Also, to supporting a multidimensional analysis on the database, we developed a network analysis system based on a hierarchy structure of chemical, gene/protein and biological interaction information. Finally, we expect this system will be used the major tool to discover various biochemical effect by combining with molecular biology technology.

• Journal of Forest and Environmental Science
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• v.38 no.3
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• pp.141-151
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• 2022

Soil seed banks as natural storage of plant seeds play an important role in the maintenance and regeneration of watershed. Natural regeneration potential of the soil seed bank of Land use types (LUTs) in Ogun River watershed (ORW) was investigated. ORW was stratified using proportionate sampling technique into Guinea Savannah (GS), Rainforest (RF) and Swamp Forest (SF) Ecological Zones (EZs). Three LUTs: Natural Forest (NF), Disturbed Forest (DF) and Farmland (FL) were purposively selected in GS: GSNF, GSDF, GSFL; RF: RFNF, RFDF, RFFL and SF: SFNF, SFDF, SFFL, respectively. Systematic line transects was used in the laying of the sample plots. Sample plots of 25 m×25 m were established in alternate positions. Ten 1 m×1 m quadrats were randomly laid for soil core sampling from previously randomly selected ten plots. The core samples (10) were pooled per plot in each LUT and placed in individual trays. Ten trays with sterilized soil were used as control. The trays were watered regularly and checked for seedlings emergence fortnightly for 18 months. The experimental design used was 3×3 factorial experiments. ANOVA, Diversity index (H') and Similarity index (SI) were used to analyze the data. There was significant difference in seedling emergence among ecological zones and land use types (p<0.05). A total of 4,400 seedlings emerged from the soil samples. All species were distributed among 32 families. FL in the RF had the highest number of germinated seeds (705±37.33 seedlings) followed by DF in the RF (701±49.6 seedlings). The lowest emergence was in NF of the SF (199±28.41 seedlings). DF in the RF had highest number of species (34) distributed among 22 families. Emergence from soil seed bank of NF in ORW was generally with more of tree species than herbs that were predominant in FL and DF.

• The Journal of Internal Korean Medicine
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• v.40 no.6
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• pp.1081-1100
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• 2019

Objectives: This study is an overview of the meta-analysis and systematic review of randomized controlled trials investigating the clinical effectiveness and safety of pharmacopuncture for patients with stroke. Methods: Core electronic databases were searched from their inception to 21 May 2019. A measurement tool to assess systematic reviews (AMSTAR 2) was applied to screen high-quality studies. The results of these studies were summarized, and additional meta-analysis was conducted. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to evaluate the certainty of evidence. Results: Sixteen studies met eligibility criteria. Four were excluded owing to insufficiency of AMSTAR 2 or low data reliability. The finally selected 12 studies were about pharmacopuncture using either a single herb extract, such as Dengzhan xixin, Sanch, Ginkgo biloba, or Acanthopanax, or a mixture of herbs, such as Compound danshen, Shenxiong, Xingnaojing, or Mailuoning. Most of the patients were from China, with acute ischemic stroke. All the studies using a pharmacopuncture versus a non-pharmacopuncture design reported the significant superiority of pharmacopuncture on every outcome measure. On the other hand, in a few studies, pharmacopuncture was inferior to active control in improving neurological deficit. Few studies reported adverse events. Conclusions: It is difficult to apply the results of this study directly to Korea, because the level of evidence is generally low and the clinical settings and social acceptance of pharmacopuncture therapy differ in Korea and China. Further studies are warranted to confirm the domestic applicability of evidence generated in China and to create evidence that supports the domestic situation.

• Korean Journal of Oriental Medicine
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• v.15 no.3
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• pp.1-10
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• 2009

Samhwajahyangyakbang, a medical book of Hyangyak which was presumed to be published by Samhwaja in the late Goryeo dynasty, became the original source of Hyangyakganibang. As Hyangyakganibang became the original source of Hyangyakjesengjipseongbang which was supplemented to be Hyangyakjipseongbang, Samhwajahyangyakbang is a fundamental book which is the original source of Hyangyak medical books such as Hyangyakganibang and Hyangyakjipseongbang in the late Goryeo and the early Chosun dynasty. I restored the articles of Samhwajahyangyakbang, mainly focusing on the remaining articles in Hyangyakjipseongbang, followed by supplementing some other remaining articles with the help of , a database of old medical books, and then, recorded and discussed the results in the paper. 1. The remaining articles of Samhwajahyangyakbang were found in Hyangyakjipseongbang, Uibo and Uibanghappyeon. Among them, there is a prescription which is not overlapped in Uibanghappyeon. 2. The classification system of Hyangyakjipseongbang was alternatively adopted due to the absence of classification or table of contents in Samhwajahyangyakbang. 3. There are a total number of 152 articles in the restored Samhwajahyangyakbang and 151 articles out of the total number have been restored from Hyangyakjipseongbang. There are 5 articles which remain as notes in the citations of other books in Hyangyakjipseongbang. 4. There are a total number of 246 prescriptions in the restored Samhwajahyangyakbang. 5. Even though Samhwajahyangyakbang is a concise medical book, it is one of the core medical books which are cited in Hyangyakjipseongbang. In addition, it is the most frequently cited in Hyangyakjipseongbang among the Korean medical books. It implies that the compilers of Hyangyakjipseongbang considered Samhwajahyangyakbang the most valuable book among the Hyangyak medical books. It is speculated that such results could be achieved because Samhwajahyangyakbang was very popular in those days and its' printing quality was also good. On the contrary, the number of citations of Hyangyakgugeupbang is much less than that of Samhwajahyangyakbang. It is presumed that Hyangyakgugeupbang could not be distributed widely not because it was less valuable but because its' printing quality was poor.