• 제목/요약/키워드: core factor

검색결과 1,171건 처리시간 0.034초

Sustained Protein Delivery System using Core/shell Nanoparticles

  • Oh, Keun-Sang;Koo, Hyoung-Mo;Yuk, Soon-Hong
    • 한국고분자학회:학술대회논문집
    • /
    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
    • /
    • pp.180-180
    • /
    • 2006
  • A novel preparation method for core/shell nanoparticles with protein drug-loaded lipid core was designed and characterized. The lipid core is composed of lecithin and protein drug and the polymeric shell is composed of Pluronics (poly (ethylene oxide)-poly (propylene oxide)-poly(ethylene oxide) triblock copolymer, F-127 For the application of core/shell nanoparticles as a protein drug carrier, lysozyme and Vascular Endothelial Growth Factor (VEGF) were loaded into the core/shell nanoparticles by electrostatic interaction and the drug release pattern was observed by manipulating the polymeric shell.

  • PDF

코어를 사용한 새로운 자기공진형 코일구조 (A New Coil Set with Core for Magnetic Resonant Systems)

  • 허진;임춘택
    • 전력전자학회:학술대회논문집
    • /
    • 전력전자학회 2012년도 전력전자학술대회 논문집
    • /
    • pp.625-626
    • /
    • 2012
  • A coupled magnetic resonance system (CMRS) using compact coil sets with core driven by a class-E inverter was proposed. The source and load coils of conventional CMRS were replaced with two coils containing core so that the system can be quite compact in size and easy to design due to a resonance frequency for all resonant tanks regardless of coupling factor. Experiments for 500 kHz switching frequency show 40% system efficiency.

  • PDF

On-line Generation of Three-Dimensional Core Power Distribution Using Incore Detector Signals to Monitor Safety Limits

  • Jang, Jin-Wook;Lee, Ki-Bog;Na, Man-Gyun;Lee, Yoon-Joon
    • Nuclear Engineering and Technology
    • /
    • 제36권6호
    • /
    • pp.528-539
    • /
    • 2004
  • It is essential in commercial reactors that the safety limits imposed on the fuel pellets and fuel clad barriers, such as the linear power density (LPD) and the departure from nucleate boiling ratio (DNBR), are not violated during reactor operations. In order to accurately monitor the safety limits of current reactor states, a detailed three-dimensional (3D) core power distribution should be estimated from the in-core detector signals. In this paper, we propose a calculation methodology for detailed 3D core power distribution, using in-core detector signals and core monitoring constants such as the 3D Coupling Coefficients (3DCC), node power fraction, and pin-to-node factors. Also, the calculation method for several core safety parameters is introduced. The core monitoring constants for the real core state are promptly provided by the core design code and on-line MASTER (Multi-purpose Analyzer for Static and Transient Effects of Reactors), coupled with the core monitoring program. through the plant computer, core state variables, which include reactor thermal power, control rod bank position, boron concentration, inlet moderator temperature, and flow rate, are supplied as input data for MASTER. MASTER performs the core calculation based on the neutron balance equation and generates several core monitoring constants corresponding to the real core state in addition to the expected core power distribution. The accuracy of the developed method is verified through a comparison with the current CECOR method. Because in all the verification calculation cases the proposed method shows a more conservative value than the best estimated value and a less conservative one than the current CECOR and COLSS methods, it is also confirmed that this method secures a greater operating margin through the simulation of the YGN-3 Cycle-1 core from the viewpoint of the power peaking factor for the LPD and the pseudo hot pin axial power distribution for the DNBR calculation.

Mechanism of Environmentally-Induced Stress Corrosion Cracking of Zr-Alloys

  • Park, Sang Yoon;Kim, Jun Hwan;Choi, Byung Kwon;Jeong, Yong Hwan
    • Corrosion Science and Technology
    • /
    • 제6권4호
    • /
    • pp.170-176
    • /
    • 2007
  • Iodine-induced stress corrosion cracking (ISCC) properties and the associated ISCC process of Zircaloy-4 and an Nb-containing advanced nuclear fuel cladding were evaluated. An internal pressurization test with a pre-cracked specimen was performed with a stress-relieved (SR) or recrystallized (RX) microstructure at $350^{\circ}C$, in an iodine environment. The results showed that the $K_{ISCC}$ of the SR and RX Zircaloy-4 claddings were 3.3 and 4.8MPa\;m^{0.5}, respectively. And the crack propagation rate of the RX Zircaloy-4 was 10 times lower than that of the SR one. The chemical effect of iodine on the crack propagation rate was very high, which was increased $10^4$ times by iodine addition. Main factor affecting on the micro-crack nucleation was a pitting formation and its agglomeration along the grain boundary. However, this pitting formation on the grain-boundary was suppressed in the case of an Nb addition, which resulted in an increase of the ISCC resistance when compared to Zircaloy-4. Crack initiation and propagation mechanisms of fuel claddings were proposed by a grain boundary pitting model and a pitting assisted slip cleavage model and they showed reasonable results.

스퀴즈캐스팅용 Salt Core의 제조 및 용탕침투성에 관한 연구 (A Study on the Fabrication Process and Melt Infiltration of Salt Core in Squeeze Casting Method)

  • 김기배;노상우;이호인;남태운
    • 한국주조공학회지
    • /
    • 제17권4호
    • /
    • pp.402-410
    • /
    • 1997
  • Developing a salt core for squeeze casting process, two different salt cores(pure salt core and mixed salt core) were fabricated and investigated. Pure salt core was composed of 100% NaCl and mixed salt core was made by mixtures of NaCl with MgO(1%), $Na_2B_4O_7$(2%), and talc(1%) as a binder or a strengthening agent. Salt cores were compacted to various theoretical density, heat treated, and then squeeze-cast with molten Al alloy(AC8A). The compression strength of salt cores were measured and the squeeze-cast products were examined for shape retention, infiltration of molten metal into the cores, and microstructures. The shape of salt core compacted at above 75% of the theoretical density was maintained stably. The higher theoretical density of salt cores gave higher compression strength, and the compression strength of mixed salt core was higher than that of pure salt core. Namely at 90% theoretical density, the compression strength of mixed salt core was $6.3 kg/mm^2$, compared to $4.6 kgmm^2$ for pure salt core. At a squeeze casting pressure of $1000 kg/cm^2$, molten Al alloy was infiltrated into pure salt core of under 85% of the theoretical density. At squeeze casting pressure of $1000 kg/cm^2$, only mixed salt core above 90% of the theoretical density were valid, but the shape of the core was altered in the case of pure salt core at 90% of theoretical density. A key factor for developing a salt core for squeeze casting process was estimated as the ultimate compressive strength of salt core.

  • PDF

유도전동기 회전자 제작시 압입작업 평가 (Evaluations of Swaging Process for Rotor Core of Induction Motors)

  • 박상철
    • 한국산학기술학회논문지
    • /
    • 제17권10호
    • /
    • pp.21-26
    • /
    • 2016
  • 산업체에서 널리 사용되고 있는 유도전동기의 회전자를 제작하기 위하여 rotor core slot에 Cu bar를 열박음(shrinkage fit)작업으로 고정한 후 bar 표면을 punch로 원주방향으로 순차적으로 1.5~3mm 압입(swaging)작업시 rotor core slot과 bar 접촉면에 작용하는 contact tangential force의 크기와 분포를 단순화된 2차원 plane strain 해석모델을 사용하여 각각의 압입조건에 대하여 평가하였으며 또한 생산성 향상을 고려한 rotor core slot 설계시 slot 형상에 따른 접촉력 분포를 평가하여 rotor core slot 설계시 필요한 정보를 제공하고자 수치해석적인 방법을 사용하여 parametric study를 수행하였다. 이러한 탄소성 수치해석 결과 1) rotor core 압입작업시 bar 접촉면에 작용하는 contact force는 소성변형이 먼저 발생하는 bar 상부에 크게 작용하며 2) 순차적인 rotor core 압입작업시 bar 접촉면에 작용하는 total contact force는 바로 인접한 bar에 대한 압입작업에 의해서만 영향을 받으며 그 영향으로 약 55% 정도 total contact force가 증가하며 3) 생산성을 고려하여 rotor core를 설계하는 경우에 contact force를 증가시키기 위해서는 core slot의 폭보다 길이를 길게 하는 것이 바람직하다는 사실을 알 수 있었다.

코어 시편을 이용한 열화된 줄눈콘크리트 포장의 공극구조 분석 (Air-void Analysis of Deteriorated Jointed Concrete Pavement Using Concrete Core Specimen)

  • 최판길;정범석;윤경구;권수안
    • 한국콘크리트학회:학술대회논문집
    • /
    • 한국콘크리트학회 2009년도 춘계 학술대회 제21권1호
    • /
    • pp.253-254
    • /
    • 2009
  • 본 논문은 노후화된 줄눈콘크리트 포장의 열화 원인을 평가하기 위하여 수행되었다. 콘크리트 코어 시편을 사용하여 ASTM C 457 에 의거한 화상분석(Image Analysis)실험을 실시하였다. 정화시편의 공기량, 공극구조분포 및 간격계수(Spacing Factor) 정보를 수집하고 공극구조와 관계한 내구성지수(Durability Factor)를 평가하였다. 평가결과 대부분 시험편의 간격계수가 250$\mu$m 이상으로 평가되어 동결융해에 취약한 것으로 나타났다.

  • PDF

돌출형 거칠기벽이 있는 동심환형관의 유동에 대한 마찰계수 (Friction Factors for Flow in Concentric Annuli with Rib-Roughened Wall)

  • 안수환
    • 대한기계학회논문집B
    • /
    • 제23권5호
    • /
    • pp.587-592
    • /
    • 1999
  • The combined effects of radius ratio and roughness pitch ratio on the turbulent fluid flow characteristics of the fully developed flow in the annullar tubes with rib-roughened core walls were determined for Reynolds number ranging from 12,000 to 66,000. To understand the underlying physical phenomena responsible for friction factor enhancement, measurements of velocity profiles and zero shear stress and maximum velocity positions were combined to propose the friction factor correlation. Friction factors were found to be a function of the roughness pitch ratio and radius ratio.

Controlled Release of Epidermal Growth Factor (EGF) from EGF-loaded Polymeric Nanoparticles Composed of Polystyrene as Core and Poly(methacrylic acid) as Corona in vitro

  • Park, In-Kyu;Seo, Seog-Jin;Akashi, Mitsuru;Akaike, Toshihiro;Cho, Chong-Su
    • Archives of Pharmacal Research
    • /
    • 제26권8호
    • /
    • pp.649-652
    • /
    • 2003
  • Polymeric nanoparticles composed of polystyrene (PS) as core and poly(methacrylic acid) (PMA) as corona were prepared by the dispersion copolymerization. The potential of the nanoparticles as carriers for recombinant human epidermal growth factor (EGF) was investigated. The nanoparticles showed monodispersity and good water-dispersibility. The loading content of EGF to the nanoparticles was very high due to electrostatic interaction between EGF and nanoparticles. EGF was released as a pseudo-zero order pattern after initial burst effect. The nanoparticles were sufficient for A431 cells proliferation.