• 대한두개안면성형외과학회지
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• 제19권1호
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• pp.48-50
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• 2018

Bony anomaly caused by lip tie is not many reported yet. There was a case of upper lip tie wrapping into the anterior premaxilla. We represent a case of severe upper lip tie of limited lip motion, upper lips curling inside, and alveolar hypoplasia. Male patient was born on June 3, 2016. He had a deep philtral sulcus, low vermilion border and deep cupid's bow of upper lip due to tension of short, stout and very tight frenulum. His upper lip motion was severely restricted in particular lip eversion. There was anterior alveolar hypoplasia with deep sulcus in anterior maxilla. Resection of frenulum cord with Z-plasty was performed at anterior premaxilla and upper lip sulcus. Frenulum was tightly attached to gingiva through gum and into hard palate. Width of frenulum cord was about 1 cm, and length was about 3 cm. He gained upper lip contour including cupid's bow and normal vermilion border after the surgery. This case is severe upper lip tie showing the premaxillary hypoplasia, abnormal lip motion and contour for child. Although there is mild limitation of feeding with upper lip tie child, early detection and treatment are needed to correct bony growth.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.323-335
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• 2016

Breast cancer risk assessment has developed during years and evaluation of genetic factor affecting risk of breast cancer is an important component of this risk assessment. The aim of this meta-analysis was to investigate the role of XRCC1 polymorphisms (Arg194Trp, Arg280His and Arg399Gln) in risk of breast cancer among different population and categories of menopausal status.PubMed, Medline, Web of Science, and PubMed Central were systematically searched to identify studies evaluating association between breast cancer and XRCC1 gene polymorphisms (Arg194Trp, Arg280His and Arg399Gln). Two authors independently extracted required information. Odds Ratios were pooled for four genetic inheritance models using both fixed and the DerSimonian and Laird random-effect models. Egger's test and contour-enhanced funnel plot was used to evaluate publication bias and small study effect. Additional subgroup analysis was performed for menopausal status, ethnicity, and source of controls. After evaluation and applying inclusion criteria on extracted studies, fifty three studies were included in this meta-analysis. For polymorphisms of Arg194Trp and Arg280His, no significant association was observed in all genetic models. Arg194Trp had a protective effect in post-menopausal status only in homozygote model (OR=0.57 [0.37-0.88]). Arg399Gln showed significant association with breast cancer in homozygote (OR=1.21 [1.10-1.34]), dominant (OR=1.09 [1.03-1.15]) and recessive (OR=1.21 [1.09- 1.35]) genetic models. Arg399Gln was associated with higher risk in post-menopausal status for homozygote and heterozygote models. Our findings suggest that XRCC1 gene polymorphisms modify breast cancer risk in different populations and different categories of menopausal status.

• Archives of Reconstructive Microsurgery
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• 제5권1호
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• pp.80-91
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• 1996

A free rectus abdominis flap can include a variable amount of muscle length depending on recipient site requirements. There is also great flexibility in flap design in terms of size, orientation of its axis, and the level of its location over the muscle. It is safe to design the skin island across the midline. Though skin islands designed over the most inferior portion of the abdomen have not always proved reliable when based on the superior epigastric artery, free flaps based on the inferior pedicle can be successfully designed in this area. As free flap based on the inferior epigastric vessels, this flap has been useful for large head and neck defects following ablative procedures, for facial contour restoration as a buried flap, for upper extremity defects, for lower extremity defects such as coverage of grade III tibial fractures and for breast reconstruction. A free rectus abdominis muscle or myocutaneus flap was used in 8 patients. The operations were performed between Sep. of 1994 and April of 1996. The patients were tongue cancer 1 case, chronic facial palsy 1 case, unilateral breast reconstruction 1 case, upper and lower extremity injury 5 cases. The free rectus abdominis muscle flaps were 4 cases and the free myocutaneous flaps were 4 cases. There was no failure of the flap, except one partial necrosis. One case of the skin grafts on the muscle flap was regrafted. One case of reoperation due to venous thrombosis was performed. In tongue cancer patient, a orocutaneous fistula was occurred, but conservative treatment and secondandry skin graft were done. In conclusion, a free rectus abdominis flap has many advantages such as a long and constant pedicle, easy dissection, enough soft tissue available, scar on the donor site to be hiddened, no need for changing position. So we think that this flap is the most useful one for small or moderate sized defects on the various sites.

• Archives of Plastic Surgery
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• 제34권5호
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• pp.628-634
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• 2007

Purpose: Subcutaneous mastectomy has been accepted as a standard for the treatment of gynecomastia. Surgical managements including ultrasound-assisted liposuction(UAL) have had limited success and several combined approaches were tried to find the most effective method. We designed a modified subcutaneous mastectomy, which we call "pan-cake method". The purpose of this study is to evaluate the results of our method for the treatment of gynecomastia. Methods: 16 patients from 16 to 31 years of age having gynecomastia were operated using the pan-cake method. 11 patients were in grade I, and 5 patients were in grade II, no patient were in grade III or IV, according to Rod's classification. The pan-cake method started with modified periareolar incision. We executed subcutaneous dissection first and suprafascial dissection next. After dividing the breast into four equal quadrants, we removed breast tissue from each quadrant as necessary. The operation time for the resection was recorded and the weight of removed parenchyme tissues was measured. Results: All the operations were successful. There were no asymmetries, contour deformities, or irregularities. Only 6 cases needed the combined therapy with ultrasound-assisted liposuction(UAL) because of the step deformities. The average operation time was 24.1 minutes and the average weight of removed breast tissue was 98.1g. All the patients were satisfied with the aesthetic results. Conclusion: We concluded that the pan-cake method is an alternative option for the surgical treatment of gynecomastia, giving good aesthetic results and relatively short operation time.

• Archives of Plastic Surgery
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• 제34권2호
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• pp.237-242
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• 2007

Purpose: Gynecomastia is an abnormal increase in the volume of the male breast. Patients affected by gynecomastia with significant glandular enlargement may respond to suction alone and/or sharp dissection and excision. The purpose of this report is to introduce the indications and results of authors' two techniques. Methods: The diameter of parenchyme was determined by a pinch test after liposuction. For the parenchymal diameter less than 4 cm, ultrasound-assisted liposuction was performed, in conjunction with the "pull-out technique" to effectively remove the fibrofatty tissue of the male breast through a single 5-7 mm incision. For the parenchymal diameter more than 4 cm, ultrasound-assisted liposuction and excision were applied through 2.5 cm periareolar approach. Results: A total of 94 patients (185 breasts) underwent the operation from October 2000 to October 2003 and mean follow-up period was 12 months. The volume of aspirates ranged from 50 to 450 cc per breast. There were no major complications such as skin flap necrosis. Five reoperations were performed for 1 hypertrophic scar, 2 under-resected and 2 hematoma cases. The patient's satisfaction was high and most of them were pleased with the shape of the breasts and scars. Conclusion: These procedures can minimize scars and reduce the incidence of contour problem such as saucer deformity, and provides consistent results. Patients can return to full activities in 48 hours. It can be offered as an option for the treatment of gynecomastia.

• 대한가정학회지
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• 제27권2호
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• pp.1-19
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• 1989

Dress is an expressive art form which involves a human activity; utilizes techniques under sufficient technical control that results in the production of typical forms on the basis of aesthetic standards. This study was conducted to clarify a relationship of Impressionism and it's image in dress-Bustle style. Artists such as Manet, Renoir, Cezanne, Gogh, Gauguin, and Rodin were reviewed. Impressionism was a method of painting that consists in repoducing an impression exactly as it is experienced from contemplation nature. The Impressionists used a technique of separate, fragmented brush strokes and pure prismatic colore, aiming at rendering changing effects of light. Fashion designers such as Charles Worth, Givency, Cardin, Ungaro, and Lacroix were examined. Throughout their fashions, they focused on the naturalism of feminine and seductive image-the touch of Vegetable Venus depicted on the paintings of Manet and Renoir; expressed "unmitigated sexiness" in various forms of Bustle sytle creating a seductive beauty, revealing body contour, breast and legs, and using a fragmented motif and flowers with vivid color.

• 패션비즈니스
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• 제18권1호
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• pp.182-198
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• 2014

The main purposes of this study is to evaluate clothing behaviors according to cosmetic surgery parts and to research how the clothing style preference is expressed depending on each clothing behavior group. This study focuses on women in their 20s and 30s living in Seoul and Gyeonggi area whom have cosmetic surgery experiences. From the women being evaluated, the following groups are divided and then surveyed with equal frequency and ratio: 'facial surgery', 'face contour surgery', 'breast surgery', and 'body figure revision'. When comparing the changes in clothing style preferences before and after the cosmetic surgery, they prefer silhouettes which show body shapes, diversity of color tones, and more overall exposing preferences. After investigating the preferred clothing styles based on cosmetic surgery parts, it is being analyzed that body exposure is more aggressively expressed upon after taking the surgery because the self satisfaction is increased according to the changes in their body shapes after the surgery. Lastly, after looking into the cosmetic surgery and the clothing preferences styles of each clothing behavior group, there seems to be more breast surgeries and body figure revisions for aggressive and extroverted characters: the sex-appeal and mood switching type. It is also being analyzed that facial surgeries are more common in the passive group: information collection, trend alignment, and beauty preference. Such results are also reflected in clothing preferences styles: the biggest change is shown in the aggressive and extroverted group, the sex-appeal types.

• 통합자연과학논문집
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• 제9권2호
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• pp.113-120
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• 2016

Monopolar spindle 1 (Mps1) is an attractive cancer target due to its high expression levels in a wide range of cancer cells. Mps1 is a dual specificity kinase. It plays an essential role in mitosis. The high expression od Mps1 was observed in various grades of breast cancers. In the current study, we have developed a CoMFA model of pyridazine derivatives as Mps1 kinase inhibitors. The developed CoMFA model ($q^2=0.797$; ONC=6; $r^2=0.992$) exhibited a good predictive ability. The model was then validated by Leave out five, progressive sampling and bootstrapping and found to be robust. The analysis of the CoMFA contour maps depicted favorable and unfavorable regions to enhance the activity. Bulky positive substitution at $R^3$ position and Negative substitution in $R^1$ position is favored could increase the activity. In contrast, bulky substitution in $R^1$ position is not favored. Our results can be used in designing a potent Mps1 (TTK) inhibitor.

• Journal of Yeungnam Medical Science
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• 제13권2호
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• pp.295-301
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• 1996

1994년 3월부터 1996년 4월까지 영남대학교 의과대학 부속병원에서 절제술을 시행하여 병리조직학적으로 진단받은 엽상육종 6례와 섬유선종 4례의 초음파 소견을 후향적으로 분석한 결과 두 종괴 모두에서 모양이 비교적 둥글며 변연이 정상조직과 잘 구분되며 내부 음향이 저음향으로 균질하게 나타났으나, 엽상육종에서는 종괴 가장자리의 납작한 모양의 낭종이 6례 중 4례 관찰되어 특징적인 소견으로 생각되며 종괴 내 저음영의 격막띠 음향은 거대 섬유선종에서 더 많이 관찰되어 거대 섬유선종을 시사하는 소견으로 생각한다. 하지만 증례가 적어 통계학적 유의성은 알 수 없었으며 이에 관한 더 많은 연구가 필요할 것으로 사료된다.

• 대한방사선치료학회지
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• 제29권1호
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• pp.27-35
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• 2017

목 적: 왼편 유방암 환자의 경우 오른편 유방암 환자보다 심장과 폐 등 정상장기에 불필요한 선량이 일부 조사됨에 따라 부작용이 우려되고 있다. 이를 줄이기 위해 DIBH기법을 시행하고 있다. Conventional Radiation Therapy, Intensity Modulated Radiation Therapy, Volumetric Modulated Arc Therapy의 치료계획 방법에 따라 쇄골상 림프절과 내유 림프절을 포함한 왼편 유방암의 경우 주변 장기의 선량 값을 비교 평가하고자 한다. 대상 및 방법: 왼편 유방암 환자 중 쇄골상 림프절과 내유 림프절을 포함한 환자 8명을 대상으로 Free Breathing과 Deep inspiration breath-hold 기법을 적용하여 각각 CT-Simulation을 시행한다. 획득한 영상을 기반으로 체표윤곽을 그려 95 %$D_{max}$<110 %이 되도록 Conventional Radiation Therapy, Intensity Modulated Radiation Therapy, Volumetric Modulated Arc Therapy방법으로 계획하였다. Conventional Radiation Therapy는 쇄골상 림프절에 1문조사, 유방 부분에 접선 2문조사로 Field in Field 기법을 사용하였다. Intensity Modulated Radiation Therapy는 7개의 조사면으로 구성하였다. Volumetric Modulated Arc Therapy은 회전반경을 $290^{\circ}{\sim}179^{\circ}$으로 한 2 ARC를 이용하여 계획을 수행하였다. Eclipse의 선량체적용적을 참고하여 주변 정상 장기 선량을 분석하였다. 결 과: Deep inspiration breath-hold기법을 적용함으로 심장과 흉벽 사이의 간격은 평균 $1.6{\pm}0.6cm$ 증가하였다. 폐의 평균 선량은 $19.2{\pm}1.0Gy$로 Intensity Modulated Radiation Therapy에서 가장 작은 값이 나타났다. 심장의 $V_{30}(%)$은 $2.0{\pm}1.9$로 Intensity Modulated Radiation Therapy에서 가장 작은 값이었다. 좌전하행 관상동맥에서는 평균 선량이 $25.4{\pm}5.4Gy$로 Intensity Modulated Radiation Therapy에서 가장 작은 값으로 나타났다. 반대편 유방의 최대선량 값은 Intensity Modulated Radiation Therapy일 때 $29.7{\pm}4.3Gy$로 가장 작은 값으로 나타났다. 결 론: 주변 정상장기 선량의 값을 비교해 보았을 때, Intensity Modulated Radiation Therapy와 Volumetric Modulated Arc Therapy은 치료에 적용할 수 있는 값으로 나타났다. 이 중 Intensity Modulated Radiation Therapy가 적합한 치료계획 방법으로 사료된다.