• Title/Summary/Keyword: continuous functions

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Clinical Characteristics and Neuropsychological Profiles of the Children with ADHD and Their Siblings (주의력결핍 과잉행동장애 아동과 형제의 임상특징 및 신경심리학 소견)

  • Lee, Hyun-Jeong;Park, Jangho;Kim, Hyo-Won
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.24 no.4
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    • pp.220-227
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    • 2013
  • Objectives : This study aims to investigate the clinical characteristics and neuropsychological profiles of children with attention-deficit hyperactivity disorder (ADHD) and their siblings. Methods : Eighteen children (age $8.2{\pm}1.7$ years, 12 boys) with ADHD and their 18 siblings (age $7.8{\pm}1.6$ years, 8 boys) completed Continuous Performance (CPT), Stroop, Children's Trail Making, Rey-Kim Memory, and Kim's Frontal Executive Function tasks. The parents of these subjects underwent the Attention-Deficit/Hyperactivity Disorder Rating Scale (ARS), 10-item Parent General Behavior Inventory (P-GBI), and the Social Responsiveness Scale (SRS). Paired t-tests were used. Results : The inattention (p=.020), and hyperactivity-impulsivity (p=.001), scores of the ARS and the P-GBI score (p=.004) were significantly higher in children with ADHD than in their siblings. Deficits in social communication and motivation on SRS were higher in children with ADHD than in their siblings (p=.017 and p=.011, respectively). Z-scores of omission and commission errors as well as response time variability on visual CPT and omission errors on auditory CPT were in clinically significant range, and z-score of omission errors on auditory CPT was in borderline range in siblings. Omission (p=.018) and commission errors on Visual CPT (p=.007) were significantly higher in children with ADHD compared to their siblings. Recognition efficiency on Kim's Frontal Executive Function Task was lower in children with ADHD compared to their siblings, but in normal range in both groups. Stroop interference and figure fluency on Kims Frontal Executive Function Task were in borderline range in ADHD group, and figure fluency was in borderline range in siblings. Conclusion : Our results support a preliminary evidence for mild degree of attention deficit in ADHD siblings. Further studies are needed to examine the cognitive functions of siblings with ADHD in larger samples.

Construction of a reference stature growth curve using spline function and prediction of final stature in Korean (스플라인 함수를 이용한 한국인 키 기준 성장 곡선 구성과 최종 키 예측 연구)

  • An, Hong-Sug;Lee, Shin-Jae
    • The korean journal of orthodontics
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    • v.37 no.1 s.120
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    • pp.16-28
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    • 2007
  • Objective: Evaluation of individual growth is important in orthodontics. The aim of this study was to develop a convenient software that can evaluate current growth status and predict further growth. Methods: Stature data of 2 to 20 year-old Koreans (4893 boys and 4987 girls) were extracted from a nationwide data. Age-sex-specific continuous functions describing percentile growth curves were constructed using natural cubic spline function (NCSF). Then, final stature prediction algorithm was developed and its validity was tested using longitudinal series of stature measurements on randomly selected 200 samples. Various accuracy measurements and analyses of errors between observed and predicted stature using NCSF growth curves were performed. Results: NCSF growth curves were shown to be excellent models in describing reference percentile stature growth curie over age. The prediction accuracy compared favorably with previous prediction models, even more accurate. The current prediction models gave more accurate results in girls than boys. Although the prediction accuracy was high, the error pattern of the validation data showed that in most cases, there were a lot of residuals with the same sign, suggestive of autocorrelation among them. Conclusion: More sophisticated growth prediction algorithm is warranted to enhance a more appropriate goodness of model fit for individual growth.

Relationship between Progressive culture and arts activities and social transformation (진보적 문화예술 활동과 사회변화의 상관성 -광주민주화운동을 중심으로-)

  • LEE, Seung-Kwon;Yun, Man-sik
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.3
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    • pp.41-50
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    • 2018
  • The present article focuses on the cultural arts, the role and functions of people as intermediate to carry out the revitalization of memory. Most of the basic cultural activities and events sparked from the cardinal point of the democratization of Gwangju and the interwoven relationships this created. In other words, the events leading to Gwangju democratization movement have derived from democratic culture and art and they contributed to change and influence South Korea's revolutionary movements. As far as clarifying the concept of culture is concerned, the idea of culture is too wide to encompass it so we aim to narrow it down to the special events of 5.18 democratization movements which launched the national transformation of the cultural stage and the development of democracy in South Korea. Through this, the movement of popular culture and popular arts fostered the revolution of society. Moreover, the value of the 5.18 movement for democratization stems from democracy, human rights, the universal value of peace and so many efforts were made by popular artists until it became upgraded as a national commemoration day. Raising the people's awareness that culture could change the course of history is still necessary so that popular art and culture play a central role in people's lives. In order to fulfill the people's inherent hope it is necessary to promote aesthetic values and a continuous revolution in societal practices.

Open IPTV Platform using Overlay Multicast and Content Delivery Network (오버레이 멀티캐스트 및 콘텐츠 전달 네트워크를 적용한 개방형 IPTV 플랫폼)

  • Jung, Seung-Moon;Kang, Im-Chul;Jeon, Jin-Han
    • The Journal of the Korea Contents Association
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    • v.9 no.12
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    • pp.528-536
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    • 2009
  • Recently, the importance of IPTV providing multimedia service over IP based networks managed to provide the required level of quality of service and experience, security, interactivity and reliability has been gradually increasing by the commercialization of its service. However, the original purposes of IPTV service - contents are produced and consumed anytime, anywhere, and over any device at the same time - have not been satisfied by service providers because most services offered by service providers depend on closed IPTV platform. In this paper, we propose an open IPTV service platform that an individual or small company can easily produce contents and offer IPTV service independently from the existing closed IPTV platform.. The proposed IPTV platform exploits overlay multicast scheme to offer reasonable service under the environment where network bandwidth and processor resource are limited. It also uses CDN-like scheme to ensure the quality of transmitted contents. The performance evaluation shows that the proposed IPTV platform has the possibility of being an open IPTV platform considering its results such as the quality of transmitted contents, the transmission rate, the channel zapping time, and so on. It also shows that proposed IPTV platform could be applied to real IPTV service with continuous enhancement of its functions and user interfaces.

Conceptual Model for Women s Health (여성건강을 위한 개념적 모형)

  • 이경혜
    • Journal of Korean Academy of Nursing
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    • v.27 no.4
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    • pp.933-942
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    • 1997
  • There has recently been an increased interest in women's health from, various disciplines, with different perspectives presented according to each profession's academic background. This has led to many instances of incorrectly defining, or misinterpretation, of the issues even among professionals. Nurse scholars as well as practitioners who work in women's health care need to have a clear conceptual understanding of women's health in order to build a body of knowledge, delineate curricular activities, and set directions for professional nursing interventions. In addition, a conceptual model that may be directly utilized in practice is needed to maintain and promote women's health issues. The purpose of this study was to apply a Hybrid model, analyzing conceptual definitions and discussions related to women's health gathered from review of the literature. Further to compare analyticals the concepts and properties observed from field work, so as to present a final definition of women's health and, build a conceptual framework for a united comprehensive perspective on the concept as well as on nursing practice. Data collection and analysis consisted of a theoretical stage, field work stage, and final analysis. A heterogeneous group of professionals and lay persons, 39 in all, participated in the field work. Study findings Include several subconcepts under the concept of women's health : a woman's whole life, holistic health, quality of life, awareness of being a woman, individual nursing, self care ability, reproductive health, and family health. Thus, a comprehensive definition was built, 1. e., "Women's health care be defined as improvement in the quality of life of women through attainment of holistic health throughout the life span. With reproductive health at the core, the concept is directly related to family and national health, and includes taking care of one's own health based on awareness of being a woman and utilizing self care activities. Women's health care issues are unique and allow various responses, therefore women's health professionals need to apply individual approaches to reach solutions in attaining holistic health and improving quality of life." The constructual factors of women's health were found to be reproductive functions, diseases more common in woman, self actualization, mental health, women's health policies, sexuality, midlife changes, and marital relations, with each factor having more than three properties. Positive factors affecting women's health were found to be a normal childbearing process, a healthy lifestyle, active health management, health information, support, and resources, and interpersonal relationships. Negative factors were found to be overwhelming role stress, cultural oppression, gender inequality, distorted sexual identity, economic difficulties, misuse and/or abuse of substances, and stress. The model of women's health may be visualized as a balance scale set upon a woman's life, supporting 4 concentric circles. The innermost circle and second circle incorporate conceptual definitions of women's health, and the outer two circles represent the constructional factors and properties of women's health. Each circle has its own color that symbolizes the conceptual meaning. Positive and negative factors are represented as weights at either end of the scale, and are affected by nursing intervention, i. e., health and wellness increase when positive factors are stronger, whereas disease and illness increase when negative factors are stronger. This model is only a preliminary effort and requires much discussion and testing to be further developed. Continuous research is also required.

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Molecular and Biochemical Properties of a Cysteine Protease of Acanthamoeba castellanii

  • Hong, Yeonchul;Kang, Jung-Mi;Joo, So-Young;Song, Su-Min;Le, Huong Giang;Thai, Thl Lam;Lee, Jinyoung;Goo, Youn-Kyoung;Chung, Dong-Il;Sohn, Woon-Mok;Na, Byoung-Kuk
    • Parasites, Hosts and Diseases
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    • v.56 no.5
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    • pp.409-418
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    • 2018
  • Acanthamoeba spp. are free-living protozoa that are opportunistic pathogens for humans. Cysteine proteases of Acanthamoeba have been partially characterized, but their biochemical and functional properties are not clearly understood yet. In this study, we isolated a gene encoding cysteine protease of A. castellanii (AcCP) and its biochemical and functional properties were analyzed. Sequence analysis of AcCP suggests that this enzyme is a typical cathepsin L family cysteine protease, which shares similar structural characteristics with other cathepsin L-like enzymes. The recombinant AcCP showed enzymatic activity in acidic conditions with an optimum at pH 4.0. The recombinant enzyme effectively hydrolyzed human proteins including hemoglobin, albumin, immunoglobuins A and G, and fibronectin at acidic pH. AcCP mainly localized in lysosomal compartment and its expression was observed in both trophozoites and cysts. AcCP was also identified in cultured medium of A. castellanii. Considering to lysosomal localization, secretion or release by trophozoites and continuous expression in trophozoites and cysts, the enzyme could be a multifunctional enzyme that plays important biological functions for nutrition, development and pathogenicity of A. castellanii. These results also imply that AcCP can be a promising target for development of chemotherapeutic drug for Acanthamoeba infections.

Estimation of Mega Flood Using Mega Rainfall Scenario (거대강우 시나리오를 이용한 거대홍수량 산정)

  • Han, Daegun;Kim, Deokhwan;Kim, Jungwook;Jung, Jeawon;Lee, Jongso;Kim, Hung Soo
    • Journal of Wetlands Research
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    • v.21 no.spc
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    • pp.90-97
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    • 2019
  • In recent years, flood due to the consecutive storm events have been occurred and property damage and casualties are in increasing trend. This study calls the consecutively occurred storm events as a mega rainfall scenario and the discharge by the scenario is defined as a mega flood discharge. A mega rainfall scenario was created on the assumption that 100-year frequency rainfall events were consecutively occurred in the Gyeongancheon stream basin. The SSARR (Streamflow Synthesis and Reservoir Regulation) model was used to estimate the mega flood discharge using the scenario in the basin. In addition, in order to perform more reasonable runoff analysis, the parameters were estimated using the SCE_UA algorithm. Also, the calibration and verification were performed using the objective functions of the weighted sum of squared of residual(WSSR), which is advantageous for the peak discharge simulation and sum of squared of residual(SSR). As a result, the mega flood discharge due to the continuous occurrence of 100-year frequency rainfall events in the Gyeongan Stream Basin was estimated to be 4,802㎥/s, and the flood discharge due to the 100-year frequency single rainfall event estimated by "the Master Plan for the Gyeongancheon Stream Improvement" (2011) was 3,810㎥/s. Therefore, the mega flood discharge was found to increase about 992㎥/s more than the single flood event. The results of this study can be used as a basic data for Comprehensive Flood Control Plan of the Gyeongan Stream basin.

Graph Cut-based Automatic Color Image Segmentation using Mean Shift Analysis (Mean Shift 분석을 이용한 그래프 컷 기반의 자동 칼라 영상 분할)

  • Park, An-Jin;Kim, Jung-Whan;Jung, Kee-Chul
    • Journal of KIISE:Software and Applications
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    • v.36 no.11
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    • pp.936-946
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    • 2009
  • A graph cuts method has recently attracted a lot of attentions for image segmentation, as it can globally minimize energy functions composed of data term that reflects how each pixel fits into prior information for each class and smoothness term that penalizes discontinuities between neighboring pixels. In previous approaches to graph cuts-based automatic image segmentation, GMM(Gaussian mixture models) is generally used, and means and covariance matrixes calculated by EM algorithm were used as prior information for each cluster. However, it is practicable only for clusters with a hyper-spherical or hyper-ellipsoidal shape, as the cluster was represented based on the covariance matrix centered on the mean. For arbitrary-shaped clusters, this paper proposes graph cuts-based image segmentation using mean shift analysis. As a prior information to estimate the data term, we use the set of mean trajectories toward each mode from initial means randomly selected in $L^*u^*{\upsilon}^*$ color space. Since the mean shift procedure requires many computational times, we transform features in continuous feature space into 3D discrete grid, and use 3D kernel based on the first moment in the grid, which are needed to move the means to modes. In the experiments, we investigate the problems of mean shift-based and normalized cuts-based image segmentation methods that are recently popular methods, and the proposed method showed better performance than previous two methods and graph cuts-based automatic image segmentation using GMM on Berkeley segmentation dataset.

Life-Cycle Cost-Effective Optimum Design of Steel Bridges Considering Environmental Stressors (환경영향인자를 고려한 강교의 생애주기비용 최적설계)

  • Lee, Kwang Min;Cho, Hyo Nam;Cha, Cheol Jun
    • Journal of Korean Society of Steel Construction
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    • v.17 no.2 s.75
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    • pp.227-241
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    • 2005
  • This paper presents a practical and realistic Life-Cycle Cost (LCC) optimum design methodology for steel bridges considering the long-term effect of environmental stressors such as corrosion and heavy truck traffics on bridge reliability. The LCC functions considered in the LCC optimization consist of initial cost, expected life-cycle maintenance cost, and expected life-cycle rehabilitation costs including repair/replacement costs, loss of contents or fatality and injury losses, road user costs, and indirect socio-economic losses. For the assessment of the life-cycle rehabilitation costs, the annual probability of failure, which depends upon the prior and updated load and resistance histories, should be accounted for. For the purpose, Nowak live load model and a modified corrosion propagation model, which takes into consideration corrosion initiation, corrosion rate, and repainting effect, are adopted in this study. The proposed methodology is applied to the LCC optimum design problem of an actual steel box girder bridge with 3 continuous spans (40m+50m+40m=130m). Various sensitivity analyses are performed to investigate the effects of various design parameters and conditions on the LCC-effectiveness. From the numerical investigation, it has been observed that local corrosion environments and the volume of truck traffic significantly influence the LCC-effective optimum design of steel bridges. Thus, these conditions should be considered as crucial parameters for the optimum LCC-effective design.

Discrete Optimum Design of Sinusoidal Corrugated Web Girder (사인형 주름웨브보의 이산화 최적구조설계)

  • Shon, Su Deok;Yoo, Mi Na;Lee, Seung Jae
    • Journal of Korean Society of Steel Construction
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    • v.24 no.6
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    • pp.671-682
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    • 2012
  • The use of sinusoidal corrugated web girder for the box-type girders and gable steel main frames has recently been increasing very much. The reasons are that the thin web of the girder affords a significant weight reduction compared with rolled beam and welded built-up girder, and that corrugation prevents the buckling failure of the web. Improvements of the automatic fabrication process makes mass production of the corrugated web and unit possible, and applications of this girder have been extended considerably. Thus, the research for the optimum design processer considering the production data is needed practically. For doing this research, we develope the discrete optimum structural design program in consideration of production list data for the research, and the program apply to the single girder under the uniform load and the concentrated load as numerical example. We consider objective function as minimum weight of the girder, and use slenderness ratio, stress of flanges and corrugated web, and the girder deflection as the constraint functions. And also the Genetic Algorithms is adopted to search the global minimum point by using the production list as a discrete design variable. Finally, to verify the optimality of the design, we conduct a comparison of the results of the discrete optimum design with those of the continuous one, and also analyze the characteristics of the optimum cross-section.