• 제목/요약/키워드: confidence limit

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학교영양사가 요구하는 영양교육 교재의 특성 (School Dietitians Need Useful Nutrition Counseling Materials)

  • 김창임;박영숙;이정원;현화진
    • 대한영양사협회학술지
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    • 제12권3호
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    • pp.243-253
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    • 2006
  • The purpose of this study was to investigate dietitians' needs of teaching materials about nutrition education for school children in Kyonggi and Chungnam(including Daejeon) areas. This study was carried out using questionnaires via e-mail or in class to the subjects of 166 elementary school dietitians as 68 in Kyonggi and 98 in Chungnam. The number of small(less than 700 meals), medium(700-1400 meals) and large(over 1400 meals) schools based on served meals daily were 48, 62 and 56, respectively. The results are as follows: Frequency of nutrition education for students as well as for teachers was samely very low as 'once per two months' and the education used to perform during lunch time mostly. For preparing nutrition education they obtained informations from the internet(64.0%). The main topics of nutrition education they used to covered were 'et's eat breakfast', 'table manners', 'the relations of body and nutrients', 'food waste', 'foods and calorie', etc.. The largest limit of nutrition education practices faced by school dietitians were pointed out as 'lacks of teaching materials' and 'counseling techniques'. Most dietitians wanted CD or substantial teaching materials for the practices, and required their contents covering 'cooking', 'food and calories', 'let’s eat various foods', 'relations of body and nutrients', 'regular meal is important’ and etc.. Since we expect nutrition teachers to be realized soon, nutrition education/counseling is emphasized more as their duty. Even though school dietitians revealed poor self-confidence, they were positive to get improved by reeducation of nutrition counseling methods and skills. If easy and suitable education materials(CD type) are developed as good as the school dietitians desired, the materials could contribute much to better nutrition education/counseling practices at schools.

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암 분류를 위한 음의 상관관계 특징을 이용한 앙상블 분류기 (Ensemble Classifier with Negatively Correlated Features for Cancer Classification)

  • 원홍희;조성배
    • 한국정보과학회논문지:소프트웨어및응용
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    • 제30권12호
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    • pp.1124-1134
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    • 2003
  • 최근의 DNA 마이크로어레이 기술로 많은 양의 유전자 데이타를 얻을 수 있는데, 특히 암의 진단과 치료에 적용되어 암의 정확한 분류에 많은 도움을 줄 것으로 기대된다. DNA로부터 얻어지는 유전자 데이타의 양은 매우 방대하므로 이를 효과적으로 분석하는 것은 매우 중요하다. 암의 분류는 진단과 치료에 있어 매우 중요하므로 하나의 분류기에 의존한 분류 결과보다는 다수의 전문화된 분류기 결과를 결합하여 결과를 도출하는 것이 바람직하다. 일반적으로 분류기를 결합함으로써 분류 성능 및 분류 결과에 대한 신뢰도를 높일 수 있다. 앙상블 분류기의 많은 장점에도 불구하고, 오류 의존적인 분류기의 결합은 성능 향상에 한계가 있다. 본 논문에서는 암을 정확하게 분류하기 위해서 음의 상관관계를 갖는 특징으로 학습한 신경망 분류기를 결합하는 방법을 제안하고, 제안한 방법의 유용성을 체계적으로 분석하고자 한다. 세 가지 벤치마크 암 데이타에 대하여 제안한 방법을 적용하여 실험한 결과, 음의 상관관계 특징을 이용한 앙상블 분류기가 다른 분류기보다 높은 성능을 내는 것을 확인할 수 있었다.

공기중 납입자의 크기 특성과 혈액중 납농도와의 관계에 의한 허용농도 측정 (Estimation of Occupational Health Standard by Relationship between Airborne Lead Concentration by Particle Size and Lead in Blood)

  • 박동욱;백남원
    • 한국산업보건학회지
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    • 제6권2호
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    • pp.265-271
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    • 1996
  • This study was conducted to investigate distribution of lead particles by operation of industry, to evaluate the effect of particle size on the absorption to workers, and to recommend the Occupational Health Standard for lead. Total lead concentrations in the secondary smelting industry were higher than those in the battery and litharge manufacturing industry. Total lead concentrations in other industries except radiator manufacturing industry exceeded the standard of $50{\mu}g/m^3$. Only radiator manufacturing industry indicated lead concentrations significantly lower than those in other industries(p<0.05). Average blood lead level of workers was $85.1{\mu}g/dl$ in secondary smelting manufacturing, $51.3{\mu}g/dl$ in the battery manufacturing, and below $40{\mu}g/dl$ in the litharge and radiator manufacturing industry. Blood lead levels of workers by industry were significantly different(p<0.05). From relationship between airborne lead concentrations by size and lead in blood, confidence limits of airborne lead concentration equivalent to $40{\mu}g/dl$ of permissible limit in blood, was $147.9-489.8{\mu}g/m^3$ as total lead and $28.8-79.4{\mu}g/m^3$ as ACGIH-RPM. It is recommended that two separate occupational health standards for lead should be established by particle size. Airborne concentration of $150{\mu}g/m^3$ as fatal lead dust and $30{\mu}g/m^3$ as respirable lead dust was recommended.

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Development and Validation of Generalized Linear Regression Models to Predict Vessel Enhancement on Coronary CT Angiography

  • Masuda, Takanori;Nakaura, Takeshi;Funama, Yoshinori;Sato, Tomoyasu;Higaki, Toru;Kiguchi, Masao;Matsumoto, Yoriaki;Yamashita, Yukari;Imada, Naoyuki;Awai, Kazuo
    • Korean Journal of Radiology
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    • 제19권6호
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    • pp.1021-1030
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    • 2018
  • Objective: We evaluated the effect of various patient characteristics and time-density curve (TDC)-factors on the test bolus-affected vessel enhancement on coronary computed tomography angiography (CCTA). We also assessed the value of generalized linear regression models (GLMs) for predicting enhancement on CCTA. Materials and Methods: We performed univariate and multivariate regression analysis to evaluate the effect of patient characteristics and to compare contrast enhancement per gram of iodine on test bolus (${\Delta}HUTEST$) and CCTA (${\Delta}HUCCTA$). We developed GLMs to predict ${\Delta}HUCCTA$. GLMs including independent variables were validated with 6-fold cross-validation using the correlation coefficient and Bland-Altman analysis. Results: In multivariate analysis, only total body weight (TBW) and ${\Delta}HUTEST$ maintained their independent predictive value (p < 0.001). In validation analysis, the highest correlation coefficient between ${\Delta}HUCCTA$ and the prediction values was seen in the GLM (r = 0.75), followed by TDC (r = 0.69) and TBW (r = 0.62). The lowest Bland-Altman limit of agreement was observed with GLM-3 (mean difference, $-0.0{\pm}5.1$ Hounsfield units/grams of iodine [HU/gI]; 95% confidence interval [CI], -10.1, 10.1), followed by ${\Delta}HUCCTA$ ($-0.0{\pm}5.9HU/gI$; 95% CI, -11.9, 11.9) and TBW ($1.1{\pm}6.2HU/gI$; 95% CI, -11.2, 13.4). Conclusion: We demonstrated that the patient's TBW and ${\Delta}HUTEST$ significantly affected contrast enhancement on CCTA images and that the combined use of clinical information and test bolus results is useful for predicting aortic enhancement.

Tissue Transglutaminase Antibody and Its Association with Duodenal Biopsy in Diagnosis of Pediatric Celiac Disease

  • Meena, Daleep K.;Akunuri, Shalini;Meena, Preetam;Bhramer, Ashok;Sharma, Shiv D.;Gupta, Rajkumar
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제22권4호
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    • pp.350-357
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    • 2019
  • Purpose: This study aimed to evaluate a possible association between the anti-tissue transglutaminase antibody (anti-tTG) titer and stage of duodenal mucosal damage and assess a possible cut-off value of anti-tTG at which celiac disease (CD) may be diagnosed in children in conjunction with clinical judgment. Methods: This observational study was conducted at a gastroenterology clinic in a tertiary hospital from April 2012 to May 2013. Seventy children between 6-months and 18-years-old with suspected CD underwent celiac serology and duodenal biopsy. Statistical analyses were done using SPSS 16. Diagnostic test values were determined for comparing the anti-tTG titer with duodenal biopsy. An analysis of variance and Tukey-Kramer tests were performed for comparing the means between groups. A receiver operating characteristics curve was plotted to determine various cut-off values of anti-tTG. Results: The mean antibody titer increased with severity of Marsh staging (p<0.001). An immunoglobulin (Ig) A-tTG value at 115 AU/mL had 76% sensitivity and 100% specificity with a 100% positive predictive value (PPV) and 17% negative predictive value (NPV) for diagnosis of CD (p<0.001, 95% confidence interval [CI], 0.75-1). Conclusion: There is an association between the anti-tTG titer and stage of duodenal mucosal injury in children with CD. An anti-tTG value of 115 AU/mL (6.4 times the upper normal limit) had 76% sensitivity, 100% specificity, with a 100% PPV, and 17% NPV for diagnosing CD (95% CI, 0.75-1). This cut-off may be used in combination with clinical judgment to diagnose CD.

Criticality effect according to axial burnup profiles in PWR burnup credit analysis

  • Kim, Kiyoung;Hong, Junhee
    • Nuclear Engineering and Technology
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    • 제51권6호
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    • pp.1708-1714
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    • 2019
  • The purpose of the critical evaluation of the spent fuel pool (SFP) is to verify that the maximum effective multiplication factor ($K_{eff}$) is less than the critical safety limit at 100% stored condition of the spent fuel with the maximum reactivity. At nuclear power plants, the storage standard of spent fuel, ie, the loading curve, is established to prevent criticality from being generated in SFP. Here, the loading curve refers to a graph showing the minimum discharged burnup versus the initial enrichment of spent fuel. Recently, US NRC proposed the new critical safety assessment guideline (DSS-ISG-2010-01, Revision 0) of PWR SFPs and most of utilities in US is following it. Of course, the licensed criterion of the maximum effective multiplication factor of SFP remains unchanged and it should be less than 0.95 from the 95% probability and the 95% confidence level. However, the new guideline is including the new evaluation methodologies like the application of the axial burnup profile, the validation of depletion and criticality code, and trend analysis. Among the new evaluation methodologies, the most important factor that affects $K_{eff}$ is the axial burnup profile of spent fuel. US NRC recommends to consider the axial burnup profiles presented in NUREG-6801 in criticality analysis. In this paper, criticality effect was evaluated considering three profiles, respectively: i) Axial burnup profiles presented in NUREG-6801. ii) Representative PWR axial burnup profile. iii) Uniform axial burnup profile. As the result, the case applying the axial burnup profiles presented in NUREG-6801 showed the highest $K_{eff}$ among three cases. Therefore, we need to introduce a new methodology because it can be issued if the axial burnup profiles presented in NUREG/CR-6801 are applied to the domestic nuclear power plants without any other consideration.

석유계총탄화수소의 위해성평가 시 적정 분획 시료수 결정에 대한 고찰 (Study on the Soil Sample Number of Total Petroleum Hydrocarbons Fractionation for Risk Assessment in Contaminated Site)

  • 전인형;김상현;정현용;정부윤;노회정;김현구;남경필
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제24권5호
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    • pp.11-16
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    • 2019
  • In this study, a reliable number of soil samples for TPH fractionation was investigated in order to perform risk assessment. TPH was fractionated into volatile petroleum hydrocarbons (VPH) with three subgroups and extractable petroleum hydrocarbons (EPH) with four subgroups. At the study site, concentrations of each fraction were determined at 18 sampling points, and the 95% upper confidence limit (UCL) value was used as an exposure concentration of each fraction. And then, 5 sampling points were randomly selected out of the 18 points, and an exposure concentration was calculated. This process was repeated 30 times, and the results were compared statistically. Exposure concentrations of EPH obtained from 18 points were 99.9, 339.1, 27.3, and 85.9 mg/kg for aliphatic $C_9-C_{18}$, $C_{19}-C_{36}$, $C_{37}-C_{40}$, and aromatic $C_{11}-C_{22}$, respectively. The corresponding exposure concentrations obtained from 5 points were 139.8, 462.8, 35.1 and 119.4 mg/kg, which were significantly higher than those from 18 points results (p <0.05). Our results suggest that limited number of samples for TPH fractionation may bias estimation of exposure concentration of TPH fractions. Also, it is recommended that more than 30 samples need to be analyzed for TPH fractionation in performing risk assessment.

강원도 횡성지역의 지하수 수질 모니터링 및 인체 위해성 평가 (Water Quality Monitoring and Risk Assessment for Groundwater at Hoengseong, Gangwon-do Province)

  • 강승혜;김기태
    • 한국환경보건학회지
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    • 제47권4호
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    • pp.356-365
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    • 2021
  • Background: Concerns have been raised regarding the criteria of groundwater, in particular in Gwangwon-do Province where many residents drink groundwater due to the poor supply of tap water and a high nonconformity rate with water quality criteria nationwide. Objectives: Water quality monitoring and risk assessment were conducted for groundwater in Hoengseong, Gangwon-do Province. Methods: A total of 46 items required for meeting drinking water criteria were analyzed from 258 samples collected from March 2017 through August 2018 (152 sites in 2017 and 106 sites in 2018). Risk assessment was conducted for two non-carcinogens (F- and NO3-N), and one carcinogen (i.e., arsenic) based on their high nonconformity to water quality criteria. Results: Water quality analysis revealed that the total proportion of nonconformities was determined to be 27.9%. The nonconformity rate for each content item is as follows: total colony counts (1.6%), total coliform (6.2%), Escherichia coli (1.2%), F- (8.1%), arsenic (4.7%), NO3-N (8.1%), pH (1.2%), manganese (0.4%), and turbidity (5.8%). Risk assessment indicated that fluoride induced a hazard quotient greater than 1 with the 95% UCL (Upper Confidence Limit) concentration of the total 258 sites and average, median, and 95% UCL concentrations of nonconformity sites. For NO3-N, there was no human health risk. For arsenic, the excess cancer risk exceeded the acceptable cancer risk of 1×10-6 with the average and 95% UCL concentrations of total 258 sites and average, median, and 95% UCL concentrations of nonconformity sites. Conclusions: This study suggests that it is necessary to expand water quality monitoring of groundwater and conduct a more detailed risk assessment in order to establish a health care plan for the residents of Hoengseong, Gangwon-do Province.

The Reliability and Validity of the Digital Goniometer and Smart Phone to Determine Trunk Active Range of Motion in Stroke Patients

  • Park, Hee-yong;Hwang, Ui-jae;Kwon, Oh-yun
    • 한국전문물리치료학회지
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    • 제29권3호
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    • pp.225-234
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    • 2022
  • Background: Trunk movements are an important factor in activities of daily living; however, these movements can be impaired by stroke. It is difficult to quantify and measure the active range of motion (AROM) of the trunk in patients with stroke. Objects: To determine the reliability and validity of measurements using a digital goniometer (DG) and smart phone (SP) applications for trunk rotation and lateral flexion in stroke patients. Methods: This is an observational study, in which twenty participants were clinically diagnosed with stroke. Trunk rotation and lateral flexion AROM were assessed using the DG and SP applications (Compass and Clinometer). Intrarater reliability was determined using intraclass correlation coefficients (ICCs) with 95% confidence intervals. Pearson correlation coefficient was used to determine the validity of the DG and SP in AROM measurement. The level of agreement between the two instruments was shown by Bland-Altman plot and 95% limit of agreement (LoA) was calculated. Results: The intrarater reliability (rotation with DG: 0.96-0.98, SP: 0.98; lateral flexion with DG: 0.97-0.98, SP: 0.96) was excellent. A strong and significant correlation was found between DG and SP (rotation hemiplegic side: r = 0.95; non-hemiplegic side: r = 0.90; lateral flexion hemiplegic side: r = 0.88; non-hemiplegic side: r = 0.78). The level of agreement between the two instruments was rotation (hemiplegic side: 23.02° [LoA 17.41°, -5.61°]; non-hemiplegic side: 31.68° [LoA 23.87°, -7.81°]) and lateral flexion (hemiplegic side: 20.94° [LoA 17.48°, -3.46°]; non-hemiplegic side: 27.12° [LoA 18.44°, -8.68°]). Conclusion: Both DG and SP applications can be used as reliable methods for measuring trunk rotation and lateral flexion in patients with stroke. Although, considering the level of clinical agreement, DG and SP could not be used interchangeably for measurements.

Performance based assessment for tall core structures consisting of buckling restrained braced frames and RC walls

  • Beiraghi, Hamid;Alinaghi, Ali
    • Earthquakes and Structures
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    • 제21권5호
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    • pp.515-530
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    • 2021
  • In a tall reinforced concrete (RC) core wall system subjected to strong ground motions, inelastic behavior near the base as well as mid-height of the wall is possible. Generally, the formation of plastic hinge in a core wall system may lead to extensive damage and significant repairing cost. A new configuration of core structures consisting of buckling restrained braced frames (BRBFs) and RC walls is an interesting idea in tall building seismic design. This concept can be used in the plan configuration of tall core wall systems. In this study, tall buildings with different configurations of combined core systems were designed and analyzed. Nonlinear time history analysis at severe earthquake level was performed and the results were compared for different configurations. The results demonstrate that using enough BRBFs can reduce the large curvature ductility demand at the base and mid-height of RC core wall systems and also can reduce the maximum inter-story drift ratio. For a better investigation of the structural behavior, the probabilistic approach can lead to in-depth insight. Therefore, incremental dynamic analysis (IDA) curves were calculated to assess the performance. Fragility curves at different limit states were then extracted and compared. Mean IDA curves demonstrate better behavior for a combined system, compared with conventional RC core wall systems. Collapse margin ratio for a RC core wall only system and RC core with enough BRBFs were almost 1.05 and 1.92 respectively. Therefore, it appears that using one RC core wall combined with enough BRBF core is an effective idea to achieve more confidence against tall building collapse and the results demonstrated the potential of the proposed system.