• 한국분말재료학회지
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• 제25권5호
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• pp.375-378
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• 2018

Conductive and dielectric SiC are fabricated using electroless plating of Ni-Fe films on SiC chopped fibers to obtain lightweight and high-strength microwave absorbers. The electroless plating of Ni-Fe films is achieved using a two-step process of surface sensitizing and metal plating. The complex permeability and permittivity are measured for the composite specimens with the metalized SiC chopped fibers dispersed in a silicone rubber matrix. The original non-coated SiC fibers exhibit considerable dielectric losses. The complex permeability spectrum does not change significantly with the Ni-Fe coating. Moreover, dielectric constant is sensitively increased with Ni-Fe coating, owing to the increase of the space charge polarization. The improvements in absorption capability (lower reflection loss and small matching thickness) are evident with Ni-Fe coating on SiC fibers. For the composite SiC fibers coated with Ni-Fe thin films, a -35 dB reflection loss is predicted at 7.6 GHz with a matching thickness of 4 mm.

• 한국자기학회지
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• 제25권1호
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• pp.10-15
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• 2015

높은 전기전도도를 가진 비자성 금속 코어와 연자성 쉘을 가진 복합와이어의 자기임피던스를 원주방향 투자율로 표현하는 모델을 맥스웰 방정식으로부터 유도하였다. Cu(직경 $100{\mu}m$)/$Ni_{80}Fe_{20}$(두께 $15{\mu}m$) 코어/쉘 복합 와이어를 전기도금방법으로 제작하였다. 코어/쉘 복합 와이어의 길이방향으로 10 kHz에서 10 MHz 범위의 주파수를 가지는 교류전류와 0 Oe에서 200 Oe 범위의 직류 자기장을 가하여 임피던스 스펙트럼의 자기장 의존성을 측정하였다. 유도된 모델을 적용하여 측정된 임피던스 스펙트럼으로부터 원주방향 복소 투자율 스펙트럼을 뽑아내었다. 뽑아낸 원주방향 복소 투자율 스펙트럼은 단일 완화주파수의 Debye 식으로 매우 잘 곡선적합되는 완화형 분산을 보였다. 원주방향 복소 투자율 스펙트럼의 자기장 의존성을 분석하여, 본 코어/쉘 복합 와이어의 경우 길이 방향의 자기이방성을 가지며 원주방향으로의 자화회전이 완화형 복소 투자율 스펙트럼에 기여하는 단일 성분이라는 것을 규명하였다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1997년도 춘계학술대회
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• pp.40-47
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• 1997

New quinolones generally have a broad antibacterial spectrum against gram-positive, gram-negative, glucose-nonfermenting and anaerobic bacteria. Some of newly developed quinolones have potent activities against S. aureus including MRSA, S.pneumoniae including PRSP, B. fragilis, chlamydiae, mycoplasmas and mycobacteria as well, and show good activities against various strains resistant to antibacterial agents of other classes. Quinolones display postantibiotic effects in vitro and are bactericidal at concentrations similar to or twice that of the minimum inhibitory concentrations (MICs) for susceptible pathogens. In experimental murine infection models including systemic infections with various pathogens such as S. aureus, S. pyogenes, S. pneumoniae, E. coli and P. aeruginosa, quinolones have shown good oral efficacy as well as parenteral efficacy. Good oral absorption and good tissue penetration of quinolones account for good therapeutic effects in clinical settings. The target of quinolones are two structurally related type II topoisomerases, DNA gyrase and DNA topoisomerase IV. Quinolones are shown to stabilize the ternary quinolone-gyrase-DNA complex and inhibit the religation of the cleaved double-stranded DNA. Bacteria can acquire resistance to quinolones by mutations of these target enzymes. Mutation sites and amino acid changes in DNA gyrase and DNA topoisomerase IV are similar in the organisms examined, suggesting that the mechanism of quinolone resistance in the target enzymes is essentially the same among various organisms. Quinolones act on both the target enzymes to different degrees depending on the organisms or agents tested, and bacteria become highly resistant to quinolones in a step-wise fashion. Incomplete cross-resistance among quinolones in some strains of E. coli and S. aureus suggests the possibility of finding quinolones active against quinolone-resistant strains which are prevailing now. To find such quinolones, the potency toward two target enzymes and the membrane permeability including influx and/or efflux systems should be taken into account.