• Title/Summary/Keyword: community assembly

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Gut Microbiota Community and Its Assembly Associated with Age and Diet in Chinese Centenarians

  • Wang, Fang;Yu, Ting;Huang, Guohong;Cai, Da;Liang, Xiaolin;Su, Haiyan;Zhu, Zhenjun;Li, Danlei;Yang, Yang;Shen, Peihong;Mao, Ruifeng;Yu, Lian;Zhao, Mouming;Li, Quanyang
    • Journal of Microbiology and Biotechnology
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    • v.25 no.8
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    • pp.1195-1204
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    • 2015
  • Increasing evidence suggests that gut microbiota underpin the development of health and longevity. However, our understanding of what influences the composition of this community of the longevous has not been adequately described. Therefore, illumina sequencing analysis was performed on the gut microbiota of centenarians (aged 100-108 years; RC) and younger elderlies (aged 85-99 years; RE) living in Bama County, Guangxi, China and the elderlies (aged 80-92 years; CE) living in Nanning City, Guangxi, China. In addition, their diet was monitored using a semiquantitative dietary questionary (FFQ 23). The results revealed the abundance of Roseburia and Escherichia was significantly greater, whereas that of Lactobacillus, Faecalibacterium, Parabacteroides, Butyricimonas, Coprococcus, Megamonas, Mitsuokella, Sutterella, and Akkermansia was significantly less in centenarians at the genus level. Both clustering analysis and UniFraq distance analysis showed structural segregation with age and diet among the three populations. Using partial least square discriminate analysis and redundancy analysis, we identified 33 and 34 operational taxonomic units (OTUs) as key OTUs that were significantly associated with age and diet, respectively. Age-related OTUs were characterized as Ruminococcaceae, Clostridiaceae, and Lachnospiraceae, and the former two were increased in the centenarians; diet-related OTUs were classified as Bacteroidales, Lachnospiraceae, and Ruminococcaceae. The former two were deceased, whereas the later one was increased, in the high-fiber diet. The age and high-fiber diet were concomitant with changes in the gut microbiota of centenarians, suggesting that age and high-fiber diet can establish a new structurally balanced architecture of gut microbiota that may benefit the health of centenarians.

Study on the Characteristics and Quality Level of Single Subject Researches in the Stroke Patients : The Field of health care ~ (뇌졸중 환자를 대상으로 한 단일대상연구의 특성과 질적 수준에 관한 연구: 보건의료 분야를 대상으로)

  • Sim, Kyoung-Bo
    • The Journal of Korean society of community based occupational therapy
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    • v.8 no.2
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    • pp.15-28
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    • 2018
  • Objective : This study sought to characterize and determine the qualitative level of a single target study for stroke patients. Methods : The National Science and Technology Information Center (NDSL), DBpia (DBpia), RISS (Radical Research Information Service), Korea Research Information (KISS), and the National Assembly Library's original case study from 2002 to 2017. A total of 24 single target research papers were selected through the screening process to analyze the quality level of research methods and research design. Results : ABA design was th most common study design method. One person was the most with 12(50%). and three were the second with 8(33.3%). Imagination was the most used as an independent lawyer. Dependent variables had the highest level of situability and one-sidedness. The study was also conducted with a variety of target behaviors, including 'memory', 'visual attention', 'dysphagia', 'visual-motor coordination', 'balance', 'activity of daily life' and 'edema' behaviors. It also showed a positive effect on all dependent variables. The Qualitative level was found to be above the intermediate level except for one study. Conclusion : It is academic significance that this study analyzes the items to be prepared for in the performance of a single target study and further studies may require the establishment of a weak but good-quality single target study for researchers conducting research in local communities and clinical sites.

The Nature of Reform in the U.S., UK, Germany National Intelligence Systems and Implications for Reform of the Korean National Intelligence Service (미국·영국·독일 국가정보체계 개혁 양상과 한국 국가정보원 개혁에 대한 시사점)

  • Yoon, Taeyoung
    • Convergence Security Journal
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    • v.18 no.2
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    • pp.167-177
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    • 2018
  • Major countries, such as the U.S., UK and Germany have reformed their national intelligence systems in the face of transnational, asymmetric and comprehensive threats since September 11, 2001 and have strengthened the intelligence capacity involved in countering terrorism and WMD proliferation, right/left extremism threats. The Korean Moon Jae-in government is preparing a reform plan to eliminate illegal political intervention and abuse of power by the National Intelligence Service(NIS) and to rebuild it as an efficient national intelligence agency for national security. In discussing the reform direction of the NIS, it is necessary to discuss in detail whether adopting a separate model of intelligence agencies to restrict domestic intelligence activities of the NIS and concentrate on foreign intelligence activities or establish new domestic intelligence agencies. Second, as for the issue of transferring anti-Communism investigation authority of the NIS to the police, it needs to be carefully considered in terms of balancing the efficiency and professionalism of intelligence agency activity in the context of North Korea's continuous military provocation, covert operations and cyber threats. Third, it should strive to strengthen the control and supervision functions of the administration and the National Assembly to ensure the political neutrality of the NIS in accordance with the democratization era, to guarantee citizens' basic rights and to improve the transparency of budget execution.

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Landscape Design for the New Government Buildings of Dalseong-gun (달성군청사 조경설계)

  • 김도경;최원만
    • Journal of the Korean Institute of Landscape Architecture
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    • v.30 no.4
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    • pp.66-73
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    • 2002
  • This landscape design proposal was presented to a design competition for the New Government Buildings of Dalseong-gun which was held by the municipal authority of Dalseong-gun in June, 2002. The site is located at 1313 Gumpo-ri, Nongong-eup, Dalseong-gun, Daegu Metropolitan City and has an area of 50,000$m^2$. The judging criteria for the landscape design set by the Dalseong-gun could be articulated as follows : an environmentally friendly design which respects the surrounding n a locale which functions as a community center of Dalseong-gun, a resting place for the welfare of its employees and visitors, and finally a place with diverse landscape elements reflecting the individual identity of each facility. The main design concepts of this project could be summarized as follows : an environmentally friendly design which respects and utilizes the existing natural landscape resources, a design which features a harmony of nature with architecture and exterior space with interior space, and a design which balances esthetic form and practical function. This design consists of four major outdoor spaces ; the lawn, the entry plaza, a pine grove, and a deck area on the third floor. The multi-purpose lawn area near the main entrance area can be used for flea markets, outdoor weddings, and picnics for its neighbors. The adjacent plaza and parking lots can be unified as one space in case of large events. The entry plaza has three axes. Each of them represents the Assembly, the Administration, and the Culture. A big circle in the paving pattern unifies the three individual axes. A group of Zelkova trees was introduced to reflect local flavor. The existing pine grove was preserved as a symbolic 'park' for the Gumpo district. The outdoor amphitheatre within the grove was introduced by utilizing the existing topography, The flow of 'nature'on the deck area was designed to connect Mt. Gumkae with the 'city'. It is a comfortable resting place for its employees and visitors.

Recent Advances in Fluid Film Bearings and Dampers for Turbomachinery (터보기계에 적용되는 유체 윤활 베어링 및 댐퍼의 최신 연구 동향)

  • Yi, Howon;Jung, Hyunsung;Kim, Kyuman;Lee, Chanwoo;Lim, Homin;Sin, Seki;Choi, Seungho;Ryu, Keun
    • Tribology and Lubricants
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    • v.36 no.4
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    • pp.215-231
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    • 2020
  • The paper presents extensive survey and review of experimental and analytical researches on fluid film bearings and squeeze film dampers (SFDs) for turbomachinery available in open literature (major archival international journals) published recently (2018 and 2019 only). Over 60 published research works are reviewed based on the research topics and objectives, the types of bearings, size of bearings, and main design parameters with a brief summary of experiments and/or predictions in each work. Some important findings and general observations about the experimental and/or predictive data are also presented. There are several major trends observed throughout the survey. A large portion of the papers focuses on bearing surface textures and effect of operating and assembly conditions on static and/or dynamic forced performances, as well as bearing surface roughness and wear patterns. Researches on geometry of orifices and recesses in hydrostatic (or hybrid) bearings, as well as bearing system stability predictions using thermohydrodynamic analysis and computational fluid dynamics (CFD), are considered as significant topics. Studies on SFDs mainly focus on experimental identification of force coefficients for various SFD geometries and sealing conditions. Reliable experiments of fluid film bearings and SFDs along with the development of experimentally benchmarked predictive tools enable reinforcement of the path for reliable implementations of the bearing components into high performance rotating machinery operating at extreme and harsh conditions. The extensive list of sources of recent experiments in the available open literature is a welcome addition to the analytical community to gauge the accuracy of predictive tools.

The Construction Work Completion of the Fuel Test Loop (핵연료 노내조사시험설비 설치공사 완료)

  • Park, Kook-Nam;Lee, Chung-Young;Chi, Dae-Young;Park, Su-Ki;Shim, Bong-Sik;Ahn, Sung-Ho;Kim, Hark-Rho;Lee, Jong-Min
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.291-295
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    • 2007
  • FTL(Fuel Test Loop) is a facility that confirms performance of nuclear fuel at a similar irradiation condition with that of nuclear power plant. FTL consists of In-Pile Test Section (IPS) and Out-Pile System (OPS). FTL construction work began on August, 2006 and ended on March, 2007. During Construction, ensuring the worker's safety was the top priority and installation of the FTL without hampering the integrity of the HANARO was the next one. Task Force Team was organized to do a construction systematically and the communication between members of the task force team was done through the CoP(community of Practice) notice board provided by the Institute. The installation works were done successfully overcoming the difficulties such as on the limited space, on the radiation hazard inside the reactor pool, and finally on the shortening of the shut down period of the HANARO. Without a sweet of the workers of the participating company of HEC(Hyundae Engineering Co, Ltd), HDEC(HyunDai Engineering & Construction Co. Ltd), equipment manufacturer, and the task force team, it is not possible to install the FTL facility within the planned shutdown period. The Commissioning of the FTL is on due to check the function and the performance of the equipment and the overall system as well. The FTL shall start operation with high burn up test fuels in early 2008 if the commissioning and licensing progress on schedule.

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Comparative Genomic Analysis of Lactobacillus plantarum GB-LP1 Isolated from Traditional Korean Fermented Food

  • Yu, Jihyun;Ahn, Sojin;Kim, Kwondo;Caetano-Anolles, Kelsey;Lee, Chanho;Kang, Jungsun;Cho, Kyungjin;Yoon, Sook Hee;Kang, Dae-Kyung;Kim, Heebal
    • Journal of Microbiology and Biotechnology
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    • v.27 no.8
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    • pp.1419-1427
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    • 2017
  • As probiotics play an important role in maintaining a healthy gut flora environment through antitoxin activity and inhibition of pathogen colonization, they have been of interest to the medical research community for quite some time now. Probiotic bacteria such as Lactobacillus plantarum, which can be found in fermented food, are of particular interest given their easy accessibility. We performed whole-genome sequencing and genomic analysis on a GB-LP1 strain of L. plantarum isolated from Korean traditional fermented food; this strain is well known for its functions in immune response, suppression of pathogen growth, and antitoxin effects. The complete genome sequence of GB-LP1 is a single chromosome of 3,040,388 bp with 2,899 predicted open reading frames. Genomic analysis of GB-LP1 revealed two CRISPR regions and genes showing accelerated evolution, which may have antibiotic and antitoxin functions. The aim of the present study was to predict strain specific-genomic characteristics and assess the potential of this new strain as lactic acid bacteria at the genomic level using in silico analysis. These results provide insight into the L. plantarum species as well as confirm the possibility of its utility as a candidate probiotic.

Next-generation Sequencing for Environmental Biology - Full-fledged Environmental Genomics around the Corner (차세대 유전체 기술과 환경생물학 - 환경유전체학 시대를 맞이하여)

  • Song, Ju Yeon;Kim, Byung Kwon;Kwon, Soon-Kyeong;Kwak, Min-Jung;Kim, Jihyun F.
    • Korean Journal of Environmental Biology
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    • v.30 no.2
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    • pp.77-89
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    • 2012
  • With the advent of the genomics era powered by DNA sequencing technologies, life science is being transformed significantly and biological research and development have been accelerated. Environmental biology concerns the relationships among living organisms and their natural environment, which constitute the global biogeochemical cycle. As sustainability of the ecosystems depends on biodiversity, examining the structure and dynamics of the biotic constituents and fully grasping their genetic and metabolic capabilities are pivotal. The high-speed high-throughput next-generation sequencing can be applied to barcoding organisms either thriving or endangered and to decoding the whole genome information. Furthermore, diversity and the full gene complement of a microbial community can be elucidated and monitored through metagenomic approaches. With regard to human welfare, microbiomes of various human habitats such as gut, skin, mouth, stomach, and vagina, have been and are being scrutinized. To keep pace with the rapid increase of the sequencing capacity, various bioinformatic algorithms and software tools that even utilize supercomputers and cloud computing are being developed for processing and storage of massive data sets. Environmental genomics will be the major force in understanding the structure and function of ecosystems in nature as well as preserving, remediating, and bioprospecting them.

Current Situation and Perspectives for Home.Visiting and School Physical Therapy in Korea (한국 가정.방문 물리치료 및 학교 물리치료의 현황과 전망)

  • Kwon, Hei-Jeoung;Kim, Yong-Kwon;Ann, Chang-Sik;Hur, Jin-Gang;Hwang, Seong-Soo
    • Journal of Korean Physical Therapy Science
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    • v.18 no.4
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    • pp.47-58
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    • 2011
  • The purpose of this study was to analyses the main factors of research papers for related with home physical therapy. This study was retrospective descriptive study, the period of data collection was from 1991 to 2011. The data was collected by the journal related in physical therapy, the dissertation of academic degree, National Assembly Library and the web-site for academic information. In the web-site, searched with the keyword 'home physical therapy' and 'after school voucher'. The results were as follows; 1. In the home physical therapy, visiting physical therapy, school physical therapy, there were different based on laws; home physical therapy was based on medical law, visiting physical therapy was based on law for community health and law for long term health insurance, school physical therapy was based on special education law. 2. The summary of research title/thema from 1991 to 2011 was as follows; for the home and visiting physical therapy 'the needs and necessity of home and visiting physical therapy' was 18 papers, 'the contents of service of home and visiting physical therapy' was 18 papers, 'program and skill development' was 16 papers, 'system developing and induction strategy of home and visiting physical therapy 'was 15 papers, 'costs of nome and visiting physical therapy' was 2 papers, 'perception and information of home and visiting physical therapy' was 9 papers, 'Recoding system and administration management' was 9 papers, 'the others 'was 14 papers, for the school physical therapy 'after school voucher system' was 9 papers, the others was 4 papers. The total papers was 114 papers. 3. Finally suggested 'Model of Educational Program for HomeVisiting and School Physical Therapy'.

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A Study on Utilization and its Model of the Private Military Companies(PMCs) in Introducing the Legal System in Korea (민간군사기업의 법제화 필요성과 그 모델에 관한 연구)

  • Kwak, SunJo
    • Convergence Security Journal
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    • v.18 no.3
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    • pp.149-161
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    • 2018
  • The private military company(PMC) or the private military industry may be one of the most important, but little understood developments in security studies to have taken place over the last decade. This new industry, where firms not only supply the goods of warfare, but rather fulfill many of the professional service functions, is not only significant to the defence community, but has wider ramifications for global politics and warfare. The private military industry emerged in the early 1990s. Its underlying cause was the confluence of three momentous dynamics - the end of the Cold War and the vacuum this produced in the market of security, transformations in the nature of warfare, and the normative rise of privatization. In order to introduce MPFs(Military Provider Firms) into Korea, where in principle private citizens are prohibited to own a gun, unlike the United States, a special law should be enacted which allows them to possess weapons and fight in combat. Therefore, the National Assembly of Korea has been submitting and discussing "the Act on the Prevention and Conduction of Practice of Piracy" since 2014.

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