• 한국응급구조학회지
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• 제12권1호
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• pp.69-80
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• 2008

During New year's day and Thanksgiving holiday, the 1339 Information Center in Gwangju and Jeonnam received an emergency medical situation and carried out the analysis as follows ; 1. The reason for the higher phone guidance(72%) of the hospital was based on the simple query for the pain control rather than emergency care. This was explained by the unfamiliar environment of the holiday movers. Pharmaceutical guidance(12.6%) in rural area was also given during the holidays. 2. The disease counselling(2.4%) and emergency treatment instruction(First Aid)(1.6%) decreased because of the small number of request for the diseases. This explained the decrease of the disease counselling. 3. The phone calls increased 8-13 times more than usual. Five-day holidays could have more emergency patients than three-day holidays. During New year's day and Thanksgiving day, the number of received phone calls was 6,444(25.7%) and this accounted for one fourth of the total number in 2007. 4. The number of the patients increased on New year's day and Thanksgiving day because most of the medical institutions and pharmacy were off duty. 5. The patients were centered in Internal medicine and pediatrics. This showed the food-borne diseases and air-borne infection such as common cold. 6. During Thanksgiving day, ophthalmologic patients having viral keratoconjunctivitis(Apollo eye disease) increased 8 folds than in New year's day. It was estimated from the continuous epidemic of Apollo eye disease. 7. There broke out the traffic accidents, food poisoning, infectious diseases, dermatological diseases due to seasonal and environmental changes during the holiday move.

• Osong Public Health and Research Perspectives
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• 제9권6호
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• pp.334-339
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• 2018

Objectives: Human rhinoviruses (HRVs) are the major cause of the common cold. Currently there is no registered, clinically effective, antiviral chemotherapeutic agent to treat diseases caused by HRVs. In this study, the antiviral activity of dexamethasone (DEX) against HRV1B was examined. Methods: The anti-HRV1B activity of DEX was assessed by sulforhodamine B assay in HeLa cells, and by RT-PCR in the lungs of HRV1B-infected mice. Histological evaluation of HRV1B-infected lungs was performed and a histological score was given. Anti-HRV1B activity of DEX via the glucocorticoid receptor (GCR)-dependent autophagy activation was assessed by blocking with chloroquine diphosphate salt or bafilomycin A1 treatment. Results: In HRV1B-infected HeLa cells, treatment with DEX in a dose-dependent manner, resulted in a cell viability of > 70% indicating that HRV1B viral replication was reduced by DEX treatment. HRV1B infected mice treated with DEX, had evidence of reduced inflammation and a moderate histological score. DEX treatment showed antiviral activity against HRV1B via GCR-dependent autophagy activation. Conclusion: This study demonstrated that DEX treatment showed anti-HRV1B activity via GCR-dependent autophagy activation in HeLa cells and HRV1B infected mice. Further investigation assessing the development of topical formulations may enable the development of improved DEX effectiveness.

• 화훼연구
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• 제16권2호
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• pp.93-101
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• 2008

식물재료로는 꽃차로 이용되고 있는 식물 중 한의학 서적에 약효가 기록되어 있는 55종을 대상으로 하였다. 이들 식물의 한의학적인 약효를 해표약, 이수약, 청열약, 사하약, 보익약, 보기약, 보혈약, 온리약, 이기약, 방향화습약과 활혈약 등 11군으로 분류하였다. 또한 이 식물들은 열(열, 온, 미온, 평, 량, 한), 맛(달다, 쓰다, 맵다, 시다, 짜다), 독성(있다, 없다) 별로 분류되었다. 꽃차의 음용은 일반적으로 모든 사람에게 이용가능할 것으로 알려져 있다. 그러나 꽃차를 음용 할 때는 본인의 체질과 건강상태에 맞는 꽃차를 선택하는 것이 중요하다. 독성이 있는 식물을 꽃차로 음용 할 때는 주의를 기울여야하고 몸이 허약한 사람은 음용을 금해야 한다. 앞으로 좀 더 많은 임상적인 연구가 진행된다면 꽃차의 건강학적 효능에 따른 상품화가 가능할 것으로 판단된다.

• 한국패류학회지
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• 제22권1호
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• pp.63-86
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• 2006

A list of species of bivalve mollusks, their local distributions and relative abundance in Yeongil Bay were analysed. Species richness ranging from 1 to 37 species was low (less than 10) in some stations at the entrance and in the central part of the bay. Fifteen species (Acila insignis, Nucula tenuis, Yoldia notabilis, Mytilus galloprovincialis, Arca boucardi, Axinopsida subquadrata, Felaniella usta, Mactra chinensis, Raeta pulchella, Nitidotellina hokkaidoensis, Theora fragilis, Alvenius ojianus, Callithaca adamsi, Ruditapes philippinarum and Laternula anatina) were most frequently encountered, and seven of them were most abundant numerically (per sample): Th. fragilis in the inner bay, A. insignis, N. tenuis, and A. ojianus in the outer bay, and C. adamsi, A. subquadrata, R. puichella in both parts. Local distributions of common species were described and presented in plotted data, and three distribution patterns were recognized. Biogeographical analysis shows that a majority of species (55%) belongs to the subtropical group, tropical-subtropical species (16%) play a relatively significant role, and the percentage of boreal (temperate) and boreal-arctic species is 18% which characterizes the whole fauna as subtropical. Zonal-biogeographical composition and number of species in families in Yeongil Bay are compared with those of some Japanese (Wakasa and Mutsu) and Russian (Peter the Great, Possjet and Amursky) bays of the East Sea. The absence of a number of typical warm-water embaymental mollusks in Yeongil Bay found in the north further East Sea and Japan, and the similar zonal-biogeographical structure of the inner and outer bay faunas are explained by active water exchange due to the openness of the bay, relatively low summer temperatures, and presence of upwelled cold waters.

• Earthquakes and Structures
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• 제20권4호
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• pp.377-388
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• 2021

Thin perforated Steel Plate Shear Walls (SPSWs) are among the most common types of seismic energy dissipation systems to protect the main boundary components of SPSWs from fatal fractures in the high-risk zones. In this paper, the cyclic behavior of the different circular hole patterns under cyclic loading is reported. Based on the experimental results, it can be concluded that a change in the perforation pattern of the circular holes leads to a change in the locations of the fracture tendency over the web plate, especially at the plate-frame interactions. Accordingly, the cyclic responses of the tested specimens were simulated by finite element method using the ABAQUS package. Likewise, perforated shear panels with a new perforation pattern obtained by implementing Topology Optimization (TO) were proposed. It was found that the ultimate shear strength of the specimen with the proposed TO perforation pattern was higher than that of the other specimens. In addition, theoretical equations using the Plate-Frame Interaction (PFI) method were used to predict the shear strength and initial stiffness of the considered specimens. The theoretical results showed that the proposed reduced coefficients relationships cannot accurately predict the shear strength and initial stiffness of the considered perforated shear panels. Therefore, the reduced coefficients should be adopted in the theoretical equations based on the obtained experimental and numerical results. Finally, with the results of this study, the shear strength and initial stiffness of these types of perforated shear panels can be predicted by PFI method.

• 한국노년학
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• 제38권4호
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• pp.1015-1033
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• 2018

본 연구의 목적은 임대주택에 거주하는 남성 독거노인의 홀로 살아가는 삶의 의미와 본질을 살펴보는 것이다. 연구방법은 현상학적 연구 방법 중 Giorgi(2009)가 제안한 분석방법을 활용하였다. 연구 참여자는 임대주택에 거주하고 있는 남성 독거노인 10명을 네크워크표집방법을 활용해 선정하였다. 연구자료는 1인 당 2회씩의 심층면담을 통해 수집하였다. 연구결과, 남성 독거노인으로 살아가는 것은 세상이라는 광야에 홀로 서서 찬바람을 맞는 것과 같았으며, 외롭고 적적한 생을 살아가는 과정은 삶과 죽음 사이의 끊임없는 힘겨루기와 같았다. 그들에게 있어 임대주택은 세상과 단절시켜 자신을 가두어 놓는 철책이자 떠돌이 생활의 종착지였다. 임대주택은 세인들에게는 안정적 울타리지만 참여자들에게는 광야에 홀로 선 심정으로 생존에 의한 본능과 죽음의 본능이 줄다리기하는 양면적 삶을 살아내는 곳이었다. 연구자는 연구결과에 근거하여 심리적 주거안정, 대중 매체 속 노인폄하, 심리적 고립 해소방안에 관한 논의와 그에 따른 제언을 했다.

• 농촌의학ㆍ지역보건
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• 제44권2호
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• pp.65-72
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• 2019

목적 : 이 연구는 네팔 루팡디 지역의 도시 빈민 거주자를 대상으로 가정에서의 감염병 유병률과 그 관련 위험요소를 파악하기 위해 수행하였다. 자료 및 방법 : 이 연구는 단면연구로서 2018년 11월 25일부터 12월 7일까지 네팔 루팡디 빈민가에 있는 259개의 가구를 선정하여 조사하였다. 가구 내 감염병 유병률을 조사하였고, 이에 관련된 위험요소는 다변량로지스틱 회귀분석을 통해 분석하였다. 결과 : 연구결과 259명의 참여자 중 2/3이상(71.8%)이 지난 1년 이내에 감염병을 적어도 하나 이상 앓았다고 응답하였고, 그중 가장 많이 앓은 감염병은 감기, 기침 및 설사로서 91.9%이었다. 다변량분석 결과 집에 적절한 조명이 없는 경우 감염병의 유병률이 더 높았다(OR 2.75, 95% CI 1.36-5.59). 결과 : 앞으로 네팔에서 건강증진 사업 또는 도시계획을 할 때 감염병의 유병률과 이에 대한 위험요인을 동시에 고려해야 할것이다.

• 대한약침학회지
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• 제23권4호
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• pp.252-261
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• 2020

Objectives: Chronic diseases (CDs) continue to increase due to advances in medicine and increase in lifespan, affecting quality of life and resulting in economic loss through treatment costs. This study addressed the perception characteristics of the effectiveness of Korean medicine (KM) based on the existence of a CD to determine the national preference for KM treatment. Methods: Using data from the 2017 National Survey of KM Usage, we evaluated the perception on treatment effect of 16 diseases by dividing them into the CD group and the non-CD group. Response reliability was verified by applying the chi-square test (χ2-test) analysis method of the Statistical Package for the Social Sciences (SPSS) statistical program. Results: The analysis of the perception on effectiveness of KM for patients with CD (n = 1,050, 21.0%) and for patients with non-CD (n = 3,950, 79.0%) showed an overall similar trend for all the 16 diseases. The response rates of having some treatment effect were high for nine diseases namely, disc-related disease (CD: 70.7%, non-CD: 73.1%), osteoarthritis (CD: 72.3%, non-CD: 72.4%), frozen shoulder and shoulder pain (CD: 79.6%, non-CD: 81.4%), back pain (CD: 84.6%, non-CD: 85.0%), sprain (CD: 84.8%, non-CD: 84.1%), facial nerve paralysis (CD: 73.5%, non-CD: 71.7%), stroke (CD: 66.2%, non-CD: 62.8%), digestive disease (CD: 53.3%, non-CD: 50.0%), and common cold and rhinitis (CD: 44.7%, non-CD: 44.8%). Conclusion: The present results found that there was little difference in the perception on effectiveness of KM for each of the 16 diseases in patients with CD and non-CD, however, 70% or more of the respondents recognized some treatment effect on musculoskeletal disorders, regardless of the existence of CD. Preferential political support for KM treatment of chronic musculoskeletal disorders is recommended.

• 동의생리병리학회지
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• 제34권6호
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• pp.309-318
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• 2020

Besides respiratory infection, COVID-19 has many neurological symptoms not only loss of smell and taste but also fatigue and brain fog. But it is a challenge to treat the neurological symptoms especially of anosmia and ageusia. In order to search for the therapeutic methods, the geographical diversity and pathological mechanisms of the COVID-19 and two symptoms were investigated from the latest clinical studies. Because the environmental conditions of the monsoon climate zone of East Asia and the Mediterranean and Oceanic climate zone of Italy, Britain, United States and tropical Brazil are different, each of diverse etiology and internal milieu should be considered differently in the treatment. SARS-CoV-2 exhibits the dampness-like characteristics and the olfactory and gustatory disorders are particularly more common than other flu or cold. and it tends to show features of damaging the lung qi of olfaction and heart-spleen qi of gustation. The mechanisms of olfactory and gustatory loss are various according to precursory, inflammatory, non-inflammatory and sequelar forms, so the therapeutic method should be designed for each period and pathology. If the process of inflammation arises from nasal and respiratory, olfactory epithelium to the central nervous structure by way of blood brain barrier, the treatment should be corresponded with the stage and depth of pathogen place. And if the olfactory loss is asymptomatic or in the initial stage, it can be applied intranasal topical scent therapy to relieve temporary locking of qi movement, but maybe also used in parallel together with herbs of relieving dampness toxin latent in the lung parenchyma.

• 동의생리병리학회지
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• 제34권4호
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• pp.159-169
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• 2020

Shanghanlun (Treatise on Cold Damage Diseases) is the oldest document in the literature on clinical records of Traditional Asian medicine (TAM), on which TAM theories about symptoms-herbs relationships are based. In this study, we aim to quantitatively explore the relationships between symptoms and herbs in Shanghanlun. The text in Shanghanlun was converted into structured data. Using the structured data, Term Frequency - Inverse Document Frequency (TF-IDF) scores of symptoms and herbs were calculated from each chapter to derive the major symptoms and herbs in each chapter. To understand the structure of the entire document, principal component analysis (PCA) was performed for the 6-dimensional chapter space. Bipartite network analysis was conducted focusing on Jaccard scores between symptoms and herbs and eigenvector centralities of nodes. TF-IDF scores showed the characteristics of each chapter through major symptoms and herbs. Principal components drawn by PCA suggested the entire structure of Shanghanlun. The network analysis revealed a 'multi herbs - multi symptoms' relationship. Common symptoms and herbs were drawn from high eigenvector centralities of their nodes, while specific symptoms and herbs were drawn from low centralities. Symptoms expected to be treated by herbs were derived, respectively. Using measurable metrics, we conducted a computational study on patterns of Shanghanlun. Quantitative researches on TAM theories will contribute to improving the clarity of TAM theories.