• Journal of Pharmaceutical Investigation
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• v.23 no.4
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• pp.231-254
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• 1993

These days, it is not uncommon that a same kind of drug is circulated globally. However, the qualities of excipients used in the same drug have to be sometimes different depending on the different requirements in the qualities stipulated by each country. For a supplier of pharmaceutical excipients, it is generally necessary to carry out different tests on the same kind of testing criteria depending on the country of destination. Thus, the discrepancies between compendium requirements of pharmaceutical excipients create severe problems in various area of industrial activities. The decision of the United States Pharmacopoeia, European Pharmacopoeia and Japanese Pharmacopoeia Commissions to harmonize the requirements is a unique chance for the industries to overcome these problems. On the other hand, discrepancies of general test methods and requirements in each monograph of pharmaceutical excipient between the compendia valid at present are in most cases extensive. Consequently their harmonization needs a lot of detailed work requiring strong support from the industry. Based on these circumstances, pharmaceutical excipients councils have been established first in U.S.A. and successively in Europe and in Japan to contribute to the harmorization process. We should like to review here the progress since the Orlando Conference in 1991 and comment about the matters at issue with regard to the international harmonization of pharmaceutical excipients.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.1
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• pp.49-56
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• 2016

Flapper Valve of Korean Utility Helicopter(KUH-1) is an essential equipment in Environmental Control System(ECS) for pilot to perform flight mission. It provides pilots and crews with heating, ventilating and air conditioning. It has function of maintaining room temperature to sustain operational capability for pilot and crew. This paper summarizes pilot comments in flight test which are classified by cause of occurrence and the troubleshooting process about each comment. It also describes design improvements which was derived from troubleshooting and suggests verification results of flight test at low temperature.

• Korean Journal of Agricultural and Forest Meteorology
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• v.11 no.3
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• pp.118-122
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• 2009

Net Radiation ($R_N$) is the major driving force for biophysical and biogeochemical processes in the terrestrial ecosystems, which is one of the most critical variables in both measurement and modeling. Despite its importance, there are only 10 weather stations conducting $R_N$ measurements among the 544 stations operated by Korea Meteorological Administration (KMA; KMA, 2008). The measurement of incoming shortwave radiation ($R_S{\downarrow}$) is, however, conducted at 22 stations while that of sunshine duration is conducted at all the manned stations. In this context, the recent research for estimating $R_N$ using $R_S{\downarrow}$ in Korean peninsula by Kwon (2009) is of great worth. The author used a linear regression and the radiation balance methods. We generally agree with the author that, in terms of simplicity and practicality, both methods show reliable applicability for estimating $R_N$. We noted, however, that the author's experimental method and analysis need some clarification and improvement, that are addressed in the following perspectives: (1) the use of daily integrated data for regression, (2) the use of measured albedo, (3) the use of linear coefficients for whole year data, (4) methodological improvement, (5) the use of sunshine duration, and (6) the error assessment.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.11a
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• pp.351-352
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• 2007

Polymers submitted to thermo/electrical stress suffer from ageing that can drastically affect their functional behaviour. Understanding the physico/chemical processes at play during ageing and defining transport regimes in which these mechanisms start to be critical is therefore a prime goal to prevent degradation and to develop new formulation or new materials with improved properties. It is thought that a way to define these critical regimes is to investigate under which conditions (in terms of stress parameters) light is generated in the material by electroluminescence (EL). This can happen through impact excitation/ionization involving hot carriers or upon bi-polar charge recombination (a definition that excludes light from partial discharges, which would sign an advanced stage in the degradation process). After a brief review of the EL phenomenology under DC, we introduce a numerical model of charge transport postulating a recombination controlled electroluminescence. The model output is critically evaluated with special emphasize on the comparison between simulated and experimental light emission. Finally, we comment some open questions and perspectives.

• Journal of Korean Clinical Nursing Research
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• v.25 no.3
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• pp.209-220
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• 2019

Purpose: A significant amount of public opinion about nurse bullying is expressed on the internet. The purpose of this study was to analyze the linkage structures among words extracted from comments on internet articles related to nurse workplace bullying using semantic network analysis. Methods: From February 2018 to April 2019, comments made on news articles posted to the Daum and Naver web portal containing keywords such as "nurse", "Taeum", and "bullying" were collected using a web crawler written in Python. A morphological analysis performed with Open Korean Text in KoNLPy generated 54 major nodes. The frequencies, eigenvector centralities, and betweenness centralities of the 54 nodes were calculated and semantic networks were visualized using the UCINET and NetDraw programs. Convergence of iterated correlations (CONCOR) analysis was performed to identify structural equivalence. Results: This paper presents results about March 2018 and January 2019 because these months had highest number of articles. Of the 54 major nodes, "nurse", "hospital", "patient", and "physician" were the most frequent and had the highest eigenvector and betweenness centralities. The CONCOR analysis identified work environment, nurse, gender, and military clusters. Conclusion: This study structurally explored public opinion about nurse bullying through semantic network analysis. It is suggested that various studies on nursing phenomena will be conducted using social network analysis.

• Journal of The Korean Astronomical Society
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• v.33 no.1
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• pp.1-17
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• 2000

We have performed extensive simulations of response of gaseous disk in barred galaxies using SPH method. The gravitational potential is assumed to be generated by disk, bulge, halo, and bar. The mass of gaseous disk in SPH simulation is assumed to be negligible compared to the stellar and dark mass component, and the gravitational potential generated by other components is fixed in time. The self-gravity of the gas is not considered in most simulations, but we have made a small set of simulations including the self-gravity of the gas. Non-circular component of velocity generated by the rotating, non-axisymmetric potential causes many interesting features. In most cases, there is a strong tendency of concentration of gas toward the central parts of the galaxy. The morphology of the gas becomes quite complex, but the general behavior can be understood in terms of simple linear approximations: the locations and number of Lindblad resonances play critical role in determining the general distribution of the gas. We present our results in the form of 'atlas' of artificial galaxies. We also make a brief comment on the observational implications of our calculations. Since the gaseous component show interesting features while the stellar component behaves more smoothly, high resolution mapping using molecular emission line for barred galaxies would be desirable.

• Korean Medical Education Review
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• v.15 no.1
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• pp.19-24
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• 2013

In medicine, rapid changes in information, technology, socio-economic interests, and globalization affect the medical education focused on the competencies of doctors, and the number of medical schools that are adopting an outcome-based curriculum (OBC) is increasing worldwide. This paper introduces the OBC model of 5 trailblazing medical schools from the UK, US, and Australia, comparing their unique features, followed by brief comment about Canada and the EU as well. On developing an OBC, the process of establishing the top outcomes for graduates is similar and the outcomes comprise knowledge, skills, and attitudes about science, patients, colleagues, society, and themselves. Implementing the outcomes down into the sub-levels of the curriculum is much more complicated and time-consuming. Assessing the achievement of every outcome is essential and requires the use of many tools in addition to the traditional written examination. From the perspective of adult learning theory, self-directed learning, team-learning, and individual and flexible achievement are tested and executed in an OBC. The gradual expansion and further innovation of an OBC is expected so that tomorrow's doctors will be able to meet the challenges of the future.

• Earthquakes and Structures
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• v.9 no.2
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• pp.391-413
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• 2015

Damage of torsionally coupled buildings situated on soil sites has been reported in literature, however no site-specific studies are available for torsionally coupled buildings having site characteristics as a parameter. Effect of torsion is being accounted in seismic codes by the provision of design eccentricity where the dynamic to static eccentricity ratio is a parameter. In this paper, a methodology to determine dynamic to static eccentricity ratio of torsionally coupled buildings has been demonstrated for Delhi region for two torsionally coupled buildings on three soil sites. The variations of average and standard deviations of frame shears for stiff and flexible edges are studied for four eccentricity ratios for the two buildings for the three sites. From the limited studies made, it is observed that the dynamic to static eccentricity ratios observed for site-specific earthquakes are different from Indian seismic code specified value, hence a proposal is made to include a comment in Indian seismic code. Methodology proposed in this paper can be adopted for any region, for the estimation of dynamic to static eccentricity ratio for site specific earthquake.

• Journal of the Korean Society of Clothing and Textiles
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• v.42 no.6
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• pp.962-976
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• 2018

This study examined: 1) the influence of 3 social presence types including shopping companions, other consumers, and sales associates on the consumer's purchase decision at a retail store; 2) the difference in the influence by shopping situation involving shopping together or shopping alone; and 3) the differences by consumer susceptibility to social influence and self-confidence. The study conducted three experiments with the retail shopping scenario manipulating consumer's positive self-evaluation, but lack of confidence after trying on a clothing product. Experiment 1 and Experiment 2 examined the positive influence of social presence while Experiment 3 examined the negative influence. The results showed that the positive comment of a shopping companion had the highest influence on the purchase decision. Such impact was more observable under the low susceptibility to normative influence. The negative comments of sales associate and shopping companion lowered the purchase decision. There was no difference by shopping situation. The results imply that influences of social presence on the consumer's purchase decision are different by positive or negative comments and such influences are not different by shopping situation.

• International Journal of Advanced Culture Technology
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• v.10 no.3
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• pp.272-280
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• 2022

During last few years, pandemic of COVID-19 has been a global issue. Under the COVID-19, global events have been restricted or canceled to secure public hygiene and safety. Since one of the largest global events is Olympic Games, we selected recent Olympic Games as our case of analysis. Tokyo Olympic Games (TOG) was held in 2021, but it encountered a millennium disaster, the pandemic of COVID-19. In such a special period, it is of great significance to explore the emotional tendency of global views before and TOG via artificial intelligence. This paper vastly collects the TOG comment data of mainstream websites in South Korea, China, and the United States by implementing crawler program for sentiment analysis (SA). And we use a variety of sentiment analysis models to compare the accuracy of the experimental results, to obtain more reliable SA results. In addition, in the prediction results, to reduce the distortion of opinion by a minority, we introduce an algorithm called "Removing Biased Minority Opinions (RBMO)" and provide how to apply this method to the interpretation domain. Through our method, more authoritative SA results were obtained, which in turn provided a basis for predicting the sentiment tendency of countries around the world in TOG during the COVID-19 epidemic.