• Journal of Microbiology and Biotechnology
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• 제11권5호
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• pp.788-797
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• 2001

The usefulness of three PCR methods were evaluated for the epidemiological typing of Staphylococcus aureus: an enterobacterial repetitive intergenic consensus sequence PCR (ERIC-PCR), repetitive extragenic palindromic element PCR (REP-PCR), and 16S-23S intergenic spacer PCR (ITS-PCR). The analysis was performed using a collection of S. aureus strains comprised of 6 reference and 79 isolates from patients with various diseases. Among the 85 S. aureus strains tested, 6 references and 6 isolates were found to be susceptible to methicillin, whereas the remaining 73 isolates were resistant to it. PCR methods are of special concern, as conventional phenotypic methods are unable to clearly distinguish among methicillin-resistant S. aureus (MRSA) strains. The ability of the techniques to detect different unrelated types was found to be as follows: ERIC-PCR, 19 types; REP-PCR, 36 types; and ITS-PCR, 14 types. On the basis of combining the ERIC, REP, and ITS fingerprints, the 85 S. aureus strains were grouped into 56 genetic types (designated G1 to G56). The diversities for the 85 S. aureus strains, calculated according to Simpson\`s index, were 0.88 for an ERIC-PCR, 0.93 for a REP-PCR, and 0.48 for an ITS-PCR, and the diversity increased up to 0.97 when an ERIC-PCR and REP-PCR were combined. The above discrimination indices imply that the genetic heterogeneity of S. aureus strains is high. Accordingly, this study demonstrates that DNA sequences from highly conserved repeats of a genome, particularly a combination of ERIC sequences and REP elements, are a convenient and accurate tool for the subspecies-specific discrimination and epidemiologic tracking of S. aureus.

• Journal of Multimedia Information System
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• 제7권1호
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• pp.1-10
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• 2020

The image analysis is an important and predominant task for classifying the different parts of the image. The analysis of complex image analysis like histopathological define a crucial factor in oncology due to its ability to help pathologists for interpretation of images and therefore various feature extraction techniques have been evolved from time to time for such analysis. Although deep reinforcement learning is a new and emerging technique but very less effort has been made to compare the deep learning and deep reinforcement learning for image analysis. The paper highlights how both techniques differ in feature extraction from complex images and discusses the potential pros and cons. The use of Convolution Neural Network (CNN) in image segmentation, detection and diagnosis of tumour, feature extraction is important but there are several challenges that need to be overcome before Deep Learning can be applied to digital pathology. The one being is the availability of sufficient training examples for medical image datasets, feature extraction from whole area of the image, ground truth localized annotations, adversarial effects of input representations and extremely large size of the digital pathological slides (in gigabytes).Even though formulating Histopathological Image Analysis (HIA) as Multi Instance Learning (MIL) problem is a remarkable step where histopathological image is divided into high resolution patches to make predictions for the patch and then combining them for overall slide predictions but it suffers from loss of contextual and spatial information. In such cases the deep reinforcement learning techniques can be used to learn feature from the limited data without losing contextual and spatial information.

• Preventive Nutrition and Food Science
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• 제11권4호
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• pp.348-357
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• 2006

Nano is a unit that designates a billionth; accordingly nanotechnology could be described as the study and applications of the unique characteristics and phenomena of nanometer size materials. Applications of nanotechnology fall into two categories (one is top-down and the other is bottom-up). Currently, most products are the results of the top-down approach. Nanofoods have distinct functional characteristics stemming from the size, mass, chemical combinations, electrolytic features, magnetic properties of food sources at the nano level and which can be applied for safe absorption and delivery into the body. The greatest advantage of nanofood is that it permits the efficient use of small quantities of nutritional elements by increasing digestive absorption ability and by delivering natural elements without any change in their original characteristics. On the other hand, there are still unsolved problems, such as questions about safety and introduction of harmful material. The demand for new commercial food products is increasing, and commercial food producers are gradually combining nanotechnology and traditional food preparation methods. Nanofoods will improve our eating habits remarkably in the future. Tomorrow we will design nanofoods by shaping molecules and atoms. It will have a big impact on the food and food-processing industries. The future belongs to new products and new processes with the goals of customizing and personalizing consumer products. Nanotechnology is expected to be applied to not only foods themselves, but also to food packaging, production, safety, processing and storage. Also, it is believed that nanotechnology will be applied tracking finished products back to production facilities and even to specific processing equipment in those facilities. The aim of this study is the introduction of technology, applications, products, markets, R&D, and perspectives of nanofoods in the food industry.

• 한국정보과학회논문지:시스템및이론
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• 제32권6호
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• pp.279-287
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• 2005

파일 무결성 검사는 시스템 자원의 안정성 여부를 판단할 수 있는 가장 확실한 방법이지만, 관리자의 경험과 능력에 따라 검사 시간과 효과에 많은 차이가 있을 수 있다. 따라서 가능한 빠른 대웅을 필요로 하는 침입 복구 및 대웅 시스템에 바로 사용하기에는 적합하지 않으며, 또한 손상 자원의 복구에 필요한 자원의 상태 정보는 수집 가능하지만 침입을 차단하기 위해 필요한 침입 행위 주체에 대한 정보는 수집할 수 없다. 본 논문에서는 위의 두 가지 문제를 해결하기 위해 시스템 호출 감시와 파일 무결성 검사를 연동하여 실시간으로 파일의 무결성을 검사하는 rtIntegrit을 제안한다. rtIntegrit은 Syswatcher라는 시스템 호출 검사 도구를 사용하여 요청된 행위를 항상 감시한다. 만약 지정된 파일에 이상 동작이 나타나면 이의 변화에 대하여 실시간으로 무결성 검사를 수행하도록 하고, 해당 관련된 프로세스의 정보를 수집하고 보고함으로서 침입 차단에 활용하게 한다. 또한 IDMEF 형식의 표준으로 감사 자료를 생성하여, 침입 대웅 및 복구 시스템들과 쉽게 연계할 수 있다.

• 대한물리의학회지
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• 제12권2호
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• pp.91-101
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• 2017

PURPOSE: The aim of this study was to verify the effect of trunk strengthening exercise using oscillation by comparing trunk muscle thickness, as well as balance of healthy adults during exercises performed with an oscillatory device and non-oscillatory device. METHODS: Twenty-two participants were randomly assigned to one of two groups: the trunk strengthening exercise using oscillation (TSEO) group (n=11) or the trunk strengthening exercise using non-oscillation (TSEN) group (n=11). Subjects in all groups performed the exercises three days per week for 6 weeks. All subjects performed four types of exercises: pull over, seated twist, power push, and diagonal power plank. Trunk muscle thickness of the rectus abdominis (RA), internal oblique (IO), external oblique (EO), transverse abdominis (TrA), and multifidus (MT) were measured with an ultrasonography. The balance ability were evaluated using the Romberg test with eyes open, eyes closed, one-leg standing test (OLST), and limits of stability (LOS). All tests were performed before the intervention, as well as after 6 weeks and 8 weeks of exercises. RESULTS: There was a significant difference of RA, IO, TrA, and MT according to the main effect of the time (p<.05). There was a significant difference of IO and LOS according to interaction effect between the time and group (p<.05). CONCLUSION: As intended, the cyclic forces induced by the oscillating device did increase trunk muscle thickness. However, the effect was limited and significant only for the IO muscle. Combining trunk strengthening exercise with oscillation appears to be more effective in improving dynamic balance.

• 한국작물학회지
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• 제28권4호
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• pp.488-496
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• 1983

버어리종 신품종 육성을 위한 기초자료를 얻기 위하여 수량성ㆍ품질 및 내병성을 달리하는 Burley 21등 5품종을 full diallel cross하여 20개 F$_1$을 만들고 양친과 함께 공시하여 초장, 엽수 ; 초장ㆍ폭, 엽면적 및 개화일수 등 주요형질과 수량ㆍ품질에 관하여 유전력, 유전자의 분포상태 및 유전자 작용에 대하여 분석ㆍ검토한 결과를 요약하면 다음과 같다. 1. 8개 형질에 대한 협의와 광의 유전력은 각각 0.1618-0.6914와, 0.7494-0.9537 범위였으며 초장, 개화일수에서 가장 높았고 수량ㆍ품질에서 가장 낮았다. 2. 초장의 유전은 장간이 단간에 대하여 부분우성을 나타냈으며 우성유전자의 관여가 컸고 우성유전자는 increaser로 작용하였다. L8은 열성친으로 다른 4품종은 우성친으로 나타났다. 3. 엽수의 유전에는 상가적 유전자 작용이 컸고 다엽이 소엽에 대하여 부분우성이었으며 모체 품종중에는 우성과 열성유전자가 거의 동수로 분포하는 것으로 추정되었다. 4. 엽장은 장엽이 단엽에 대하여 완전우성 유전을 하는 것으로 추정되며, 엽폭에서는 광엽이 세엽에 대하여 초월우성을 보여 F$_1$의 엽면적 증대를 가져와 수량증가의 요인으로 작용하였다. 5. 개화기 유전은 조성이 만성에 대하여 부분우성으로 상가적 유전자의 작용이 컸고 관여하는 유효인자수는 1-2개 정도였으며 우성유전자는 개화기를 단축시키는 작용을 하였다. 6. 수량은 다수성이 우성인 초월우성유전을 보였으며, 품질은 질량이 우성인 완전우성 유전으로 추정되었다. L8은 두가지 형질에 대하여 열성친으로 나타났으며 4개 품종들은 우성친으로 나타났다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권7호
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• pp.2938-2956
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• 2020

Objective image quality assessment (IQA) models have been developed by effective features to imitate the characteristics of human visual system (HVS). Actually, HVS is extremely sensitive to color degradation and complex texture changes. In this paper, we firstly reveal that many existing full reference image quality assessment (FR-IQA) methods can hardly measure the image quality with contrast and masking texture changes. To solve this problem, considering texture masking effect, we proposed a novel FR-IQA method, called Texture and Color Quality Index (TCQI). The proposed method considers both in the masking effect texture and color visual perceptual threshold, which adopts three kinds of features to reflect masking texture, color difference and structural information. Furthermore, random forest (RF) is used to address the drawbacks of existing pooling technologies. Compared with other traditional learning-based tools (support vector regression and neural network), RF can achieve the better prediction performance. Experiments conducted on five large-scale databases demonstrate that our approach is highly consistent with subjective perception, outperforms twelve the state-of-the-art IQA models in terms of prediction accuracy and keeps a moderate computational complexity. The cross database validation also validates our approach achieves the ability to maintain high robustness.

• 대한한방소아과학회지
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• 제15권1호
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• pp.229-234
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• 2001

본문종술료중의견과학근50년래재기초의학 (本文綜述了中醫見科學近50年來在基礎醫學), 예방의학(預防醫學)、림증의학적발전현상화성취(臨證醫學的發展現狀和成就), 작자인위중의아과학발전적전략목표시현대화(作者認爲中醫兒科學發展的戰略目標是現代化). 금후약간년내(今后若干年內), 잉장요대력인진현대과학기술수단(仍將要大力引進現代科學技術手段), 재중의아과학기초방면(在中醫兒科學基礎方面), 가강대소견생리병리특점(加强對小見生理病理特点), 사진객관화(四診客觀化), 굉관변증여미관변증상결합(宏觀辨證與微觀辨證相結合), 약물제형개혁급약효학등연구(藥物劑型改革及藥效學等硏究) ; 재림증방면(在臨證方面), 발휘중의약우세(發揮中醫藥優勢), 심입대병독성질병(深入對病毒性疾病), 면역성질병(免疫性疾病), 영양성질병(營養性疾病), 신생아질병등적연구(新生兒疾病等的硏究), 제고료효(提高療效), 적루자료(積累資料), 온양학과현대화적변장(?釀學科現代化的變章).

• Restorative Dentistry and Endodontics
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• 제26권5호
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• pp.399-408
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• 2001

Tooth bleaching has been prevailing recently for its ability to recover the color and shape of natural teeth without reduction of tooth material. However, it has been reported that bleaching procedure adversely affects the adhesive bond strength of composite resin to tooth. At the same time the bond strength was reported to be regained by application of some chemical agents. The purpose of this in vitro study was to investigate the effect of the removal of residual peroxide on the composite- enamel adhesion and also evaluated fracture mode between resin and enamel after bleaching. Sixty extracted human anterior and premolars teeth were divided into 5 groups and bleached by combined technique using of office bleaching with 35 % hydrogen peroxide and matrix bleaching with 10% carbamide peroxide for 4 weeks. After bleaching, the labial surfaces of each tooth were treated with catalase, 70% ethyl alcohol, distilled water and filled with composite resin. Shear bond strength was tested and the fractured surfaces were also examined with SEM. Analysis revealed significantly higher bond strength values. (p＜0.05) for catalase-treated specimens, but water-treated specimens showed reduction of bond strength, alcohol- treated specimens had medium value between the two groups(p＜0.05). The fracture mode was shown that the catalase group and the alcohol group had cohesive failure but the water sprayed group had adhesive failure. It was concluded that the peroxide residues in tooth after bleaching seems to be removed by gradual diffusion and the free radical oxygen from peroxide prevents polymerization by combining catalyst in the resin monomer. Therefore it may be possible to eliminate the adverse effect on the adhesion of composite resin to enamel after bleaching by using water displacement solution or dentin bonding agent including it for effective removal of residual peroxide.

• 산업경영시스템학회지
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• 제41권3호
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• pp.176-185
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• 2018

With the recent development of manufacturing technology and the diversification of consumer needs, not only the process and quality control of production have become more complicated but also the kinds of information that manufacturing facilities provide the user about process have been diversified. Therefore the importance of big data analysis also has been raised. However, most small and medium enterprises (SMEs) lack the systematic infrastructure of big data management and analysis. In particular, due to the nature of domestic manufacturing companies that rely on foreign manufacturers for most of their manufacturing facilities, the need for their own data analysis and manufacturing support applications is increasing and research has been conducted in Korea. This study proposes integrated analysis platform for process and quality analysis, considering manufacturing big data database (DB) and data characteristics. The platform is implemented in two versions, Web and C/S, to enhance accessibility which perform template based quality analysis and real-time monitoring. The user can upload data from their local PC or DB and run analysis by combining single analysis module in template in a way they want since the platform is not optimized for a particular manufacturing process. Also Java and R are used as the development language for ease of system supplementation. It is expected that the platform will be available at a low price and evolve the ability of quality analysis in SMEs.