• Journal of applied mathematics & informatics
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• 제39권5_6호
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• pp.717-723
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• 2021

The purpose of the present paper is to give sufficient conditions for normalized Dini function which is the special combination of the generalized Bessel function of first kind to be in the classes k-starlike functions and k-uniformly convex functions.

• 대한기계학회논문집A
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• 제28권6호
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• pp.799-806
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• 2004

This paper presents a scheme for finding an optimal combination of design parameters affecting on the handling performance of a large truck using design of experiments. The average of the sum of peak-to-peak roll angles at the first and second part of the double lane is used as an objective function for design of experiments. Six design parameters are selected from all possible parameters affecting on the handling performance. The table of orthogonal arrays is made by 27 times simulations. A computational model of a large truck is developed by MSC/NASTRAN and MSC/ADAMS, and verified the reliability of it with the results of vehicle tests performed in a double lane change course. It is used for the simulations. Analyses of variance and factor effect of the table of orthogonal arrays are performed. This paper proposes an optimal combination of those six design parameters for improving the handling performance of the large truck.

• The Korean Journal of Physiology and Pharmacology
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• 제27권3호
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• pp.221-230
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• 2023

Diabetic kidney disease is one of the most serious complications of diabetes. Although diabetic kidney disease can be effectively controlled through strict blood glucose management and corresponding symptomatic treatment, these therapies cannot reduce its incidence in diabetic patients. The sodium-glucose cotransporter 2 (SGLT2) inhibitors and the traditional Chinese herb "Gegen" have been widely used in diabetes-related therapy. However, it remains unclear whether the combined use of these two kinds of medicines contributes to an increased curative effect on diabetic kidney disease. In this study, we examined this issue by evaluating the efficacy of the combination of puerarin, an active ingredient of Gegen, and canagliflozin, an SGLT2 inhibitor for a 12-week intervention using a mouse model of diabetes. The results indicated that the combination of puerarin and canagliflozin was superior to canagliflozin alone in improving the metabolic and renal function parameters of diabetic mice. Our findings suggested that the renoprotective effect of combined puerarin and canagliflozin in diabetic mice was achieved by reducing renal lipid accumulation. This study provides a new strategy for the clinical prevention and treatment of diabetic kidney disease. The puerarin and SGLT2 inhibitor combination therapy at the initial stage of diabetes may effectively delay the occurrence of diabetic kidney injury, and significantly alleviate the burden of renal lipotoxicity.

• 벤처창업연구
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• 제9권4호
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• pp.155-161
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• 2014

본 연구에서는 신제품개발의 실시에 있어서 가장 중요한 기능분석의 단계를 제품의 설계 단계에서부터 소비자의 만족도를 조사하여 반영하였다. 품질기능전개를 이용하여 전개함으로서 원가절감과 품질개선의 합리적인 기능분석을 실시하고자 하는데 그 목적이 있다. 가치공학과 품질기능전개(QFD: Quality Function Deployment) 의 상호연계에 대한 필요성과 적합성을 분석하였다. 사례연구에서는 이러한 이론적인 배경 하에 품질기능전개를 이용하여 VE 기능 분석을 의료기기 제품에 적용하였다. 본 연구결과 소비자의 만족도와 품질기능전개를 이용하여 나타난 제품의 가치가 연구결과와 일치하고 있음을 파악하였다.

• International journal of advanced smart convergence
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• 제4권1호
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• pp.35-39
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• 2015

This study was presented the small action by the budge sonance function. An estimation of budge sonance function was acquired displacements across all condition with a variation of small action. The budge sonance function was to be indicated to express the flow rate of body motion. Their function was suggested an issue of the action condition by budge sonance. This system was proposed a combination of the body motion and small action. The acquired sonance signal was to render the small action of body motion with budge sonance function. The analysis of budge function was generally realized a variation from displacements on the fast body motion. Budge sonance signal of action that vision condition was acquired to a variation of the $Vi-{\beta}_{AVG}$ with $(-4.954){\pm}(-5.42)$ units, that vestibular condition was acquired to a variation for the $Ve-{\beta}_{AVG}$ with $(-2.288){\pm}0.212$ units, that somatosensory condition was acquired to a variation for the $So-{\beta}_{AVG}$ with $(-0.47){\pm}0.511$ units, that CNS condition was acquired to a variation for the $C-{\beta}_{AVG}$ with $(-0.171){\pm}(-0.012)$ units. Budge sonance function was proposed the small action from axial action on body control. We know a body motion response from axial action was not only variation of budge sonance, but also body motion of fast body motion.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2002년도 심포지엄
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• pp.98-98
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• 2002

In higher dicotyledonous plants, the floral organs are arranged in four different whorls, containing sepals, stamens and carpels. petals, stamens and carpels. The specification of floral organ identity is explained by the ABC model (Weigel and Meyerowitz 1994). expression of an A-function gene specifies sepal formation in whorl 1. the combination of A-and B-function genes specifies the formation of petals in whorl 2, B-and C-function genes spesify stamen formation in whorl 3, and expression of the C-function alone determines the formation of carpels in whorl 1. A-, B-, C-function genes have been isolated from many plant species and most of them belong to the family of MADS-box genes encoding transcription factor. In contrast to the flower of higher dicots, the perianths of genseng plants have three whorls of almost identical petaloid organs. van Tunen et al. (1993) proposed a modified ABC model, exemplified with tulip. In this model, B-function genes are expressed in whorl 1 as well as whorl 2 and 3, theefore the organs of whorl 1 and whorl 2 have the same petaloid structure. They proposed this model with the molphological data of wild type and mutant flowers of tulip, however, there are no molecular data. To date, B-function genes were isolated several grass plants, rice, wheat and maize. However, grass plants have highly derived flowers, without well-developed perianths. To find out how the ABC model has to be modified for the Genseng plants, we have cloned and characterized orthologs of A-, B-, C-function genes from genseng.

• 디지털산업정보학회논문지
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• 제9권3호
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• pp.21-30
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• 2013

Powell-Miller theory is a good method to express or treat incorrect information. But it has limitation that requires too much time to apply to actual situation because computational complexity increases in exponential and functional way. Accordingly, there have been several attempts to reduce computational complexity but side effect followed - certainty factor fell. This study suggested expanded Approximation Algorithm. Expanded Approximation Algorithm is a method to consider both smallest supersets and largest subsets to expand basic space into a space including inverse set and to reduce Approximation error. By using expanded Approximation Algorithm suggested in the study, basic probability assignment function value of subsets was alloted and added to basic probability assignment function value of sets related to the subsets. This made subsets newly created become Approximation more efficiently. As a result, it could be known that certain function value which is based on basic probability assignment function is closely near actual optimal result. And certainty in correctness can be obtained while computational complexity could be reduced. by using Algorithm suggested in the study, exact information necessary for a system can be obtained.

• 한국가구학회지
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• 제24권4호
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• pp.318-328
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• 2013

This study aimed to examine the theoretical consideration and concept of hybrid that could be applicable to wood product design, to analyze design trend according to the morphological transformation by means of combination of hybrid material and function, to understand the correlation between type of wood product and materials and to apply it to the domestic and overseas hybrid concept of wood product design study. A study of assembling output by empirical experiment to embed natural resources into acrylic resin in order to develop wood products was carried out. And an wood product was suggested that satisfied lighting and hanger function through a new wood product design development combined with hanger function and lighting function. Through such process, a new design paradigm was suggested to cope with the periodic trend and to induce mass production of designed product. Thus, this study set a new guideline for activating wood product design and attempted to meet the social demand of encouraging new value creation.

• Journal of Power Electronics
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• 제12권5호
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• pp.830-841
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• 2012

Active power filters (APF) can be employed for harmonic compensation in power systems. In this paper, a fuzzy based method is proposed for identification of probable APF nodes of a radial distribution system. The modified adaptive particle swarm optimization (MAPSO) technique is used for final selection of the APFs size. A combination of Fuzzy-MAPSO method is implemented to determine the optimal allocation and size of APFs. New fuzzy membership functions are formulated where the harmonic current membership is an exponential function of the nodal injecting harmonic current. Harmonic voltage membership has been formulated as a function of the node harmonic voltage. The product operator shows better performance than the AND operator because all harmonics are considered in computing membership function. For evaluating the proposed method, it has been applied to the 5-bus and 18-bus test systems, respectively, which the results appear satisfactorily. The proposed membership functions are new at the APF placement problem so that weighting factors can be changed proportional to objective function.

• Reproductive and Developmental Biology
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• 제33권1호
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• pp.49-54
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• 2009

The current study was designed to evaluate the effects of the reactive oxygen species (ROS) generated with a xanthine (X) and xanthine oxidase system (XO) on sperm function and DNA fragmentation in porcine spermatozoa. ROS were produced by a combination of $1,000{\mu}M$ X and 50 mU/ml XO. The ROS scavengers such as superoxide dismutase (SOD) (200 U/ml) and catalase (CAT) (500 U/ml) were also tested. Spermatozoa were incubated for 2 hours in BWW medium with a combination of X-XO supplemented with or without antioxidants at $37^{\circ}C$ under 5% $CO_2$ incubator. Ca-ionophore-induced acrosome reaction, the proportion of swollen spermatozoa under hypo-osmotic condition, malondialdehyde formation for the analysis of lipid peroxidation, and the proportion of DNA fragmentation were determined after 2 hours incubation. The action of ROS on porcine spermatozoa resulted in decreased Ca-ionophore-induced acrosome reaction and membrane integrity, increased the formation of malondialdehyde, and the proportion of sperm with DNA fragmentation(p<0.05). The toxic effects caused by ROS were completely alleviated by CAT in terms of sperm function and characteristics, however SOD did not serve the same scavenger effect as CAT. To conclude, the ROS can cause significant damage to porcine sperm functions and characteristics, which can be minimized by the use of antioxidants.