• Title/Summary/Keyword: co-administration

Search Result 2,029, Processing Time 0.034 seconds

Quality Maintenance and Suppression of Chilling Injury of 'Akihime' Plum Fruits Stored under Controlled Atmosphere (CA 저장을 이용한 자두 '추희'의 품질유지 및 저온장해 발생 억제)

  • Lee, Eun Jin;Choi, Sunyoung;Cho, MiAe;Hong, YoonPyo;Choi, JiWeon;Chung, DaeSung
    • Horticultural Science & Technology
    • /
    • v.31 no.6
    • /
    • pp.732-739
    • /
    • 2013
  • 'Akihime' plums picked at mature stage (50-70% red coloration of the fruit skin) were stored at $1^{\circ}C$ under air or controlled atmosphere (CA) storage regime as following 3% $O_2$ + 1, 3, 5, and 7% $CO_2$ for 50 days for the purpose of assessing the effect of CA storage on the maintenance of fruit quality and the reduction of chilling injury. Fruits stored under CA storage regime showed reduced respiration as well as ethylene production rates compared to the fruits stored in air. Quality attributes including weight loss, Hunter 'a' values, soluble solids content, titratable acidity, and firmness showed smallest changes in fruits stored under CA conditions except for 3% $O_2$ + 7% $CO_2$. High incidence of physiological disorders including chilling injury, flesh browning, and decay were found in fruits stored under both air and CA of 3% $O_2$ + 7% $CO_2$. In our study, the CA storage regime of 3% $O_2$ + 5% $CO_2$ was found the most effective for maintaining overall fruit qualities of 'Akihime' plums produced in Korea, also delayed the development of chilling injury including lack of juiciness and flesh browning. From the results, storage at 3% $O_2$ + 5% $CO_2$ was selected as an optimal condition of 'Akihime' plum for extending storage life up to 50 days at $1^{\circ}C$.

Evaluation of Various Packaging Systems on the Activity of Antioxidant Enzyme, and Oxidation and Color Stabilities in Sliced Hanwoo (Korean Cattle) Beef Loin during Chill Storage

  • Kang, Sun Moon;Kang, Geunho;Seong, Pil-Nam;Park, Beomyoung;Cho, Soohyun
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.27 no.9
    • /
    • pp.1336-1344
    • /
    • 2014
  • The effects of various packaging systems, vacuum packaging (VACP), medium oxygen-modified atmosphere packaging (50% $O_2/20%$ $CO_2/30%$ $N_2$, MOMAP), MOMAP combined with vacuum skin packaging (VSP-MOMAP), high oxygen-MAP (80% $O_2/20%$ $CO_2/30%$ $N_2$, HOMAP), and HOMAP combined with VSP (VSP-HOMAP), on the activity of antioxidant enzyme, and oxidation and color stabilities in sliced Hanwoo (Korean cattle) beef loin were investigated at $4^{\circ}C$ for 14 d. Higher (p<0.05) superoxide dismutase activity and total reducing ability were maintained in VSP-MOMAP beef than in HOMAP beef. Lipid oxidation (2-thiobarbituric acid reactive substances, TBARS) was significantly (p<0.05) retarded in MOMAP, VSP-MOMAP, and VSP-HOMAP beef compared with HOMAP beef. Production of nonheme iron content was lower (p<0.05) in VSP-MOMAP beef than in HOMAP beef. Red color ($a^*$) was kept higher (p<0.05) in VSP-MOMAP beef compared with MOMAP, HOMAP, and VSP-HOMAP beef. However, VACP beef was found to have the most positive effects on the antioxidant activity, oxidation and red color stabilities among the various packaged beef. These findings suggested that VSP-MOMAP was second to VACP in improving oxidation and color stabilities in sliced beef loin during chill storage.

Annual Greenhouse Gas Removal Estimates of Grassland Soil in Korea

  • Lee, Sang Hack;Park, Hyung Soo;Kim, Young-Jin;Kim, Won Ho;Sung, Jung Jong
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.35 no.3
    • /
    • pp.251-256
    • /
    • 2015
  • The study was conducted to determine greenhouse gas (GHG) inventories in grasslands. After 'Low Carbon Green Growth' was declared a national vision on 2008, Medium-term greenhouse gas reduction was anticipated for 30% reduction compared to Business As Usual (BAU) by 2020. To achieve the reduction targets and prepare to enforce emissions trading (2015), national GHG inventories were measured based on the 1996 Intergovernmental Panel on Climate Change Guidelines (IPCC GL). The national Inventory Report (NIR) of Korea is published every year. Grassland sector measurement was officially added in 2014. GHG removal of grassland soil was measured from 1990 to 2012. Grassland area data of Korea was used for farmland area data in the "Cadastral Statistical Annual Report (1976~2012)". Annual grassland area corresponding to the soil classification was used "Soil classification and commentary in Korea (2011)". Grassland area was divided into 'Grassland remaining Grassland' and 'Land converted to Grassland'. The accumulated variation coefficient was assumed to be the same without time series changes in grassland remaining grassland. Therefore, GHG removal of soil carbon was calculated as zero (0) in grassland remaining grassland. Since the grassland area increases constantly, the grassland soil sinks constantly . However, the land converted to grassland area continued to decrease and GHG removal of soil carbon was reduced. In 2012 (127.35Gg $CO_2$), this removal decreased by 76% compared to 1990 (535.71 Gg $CO_2$). GHG sinks are only grasslands and woodlands. The GHG removaled in grasslands was very small, accounting for 0.2% of the total. However, the study provides value by identifying grasslands as GHG sinks along with forests.

Heat-Killed and Live Enterococcus faecalis Attenuates Enlarged Prostate in an Animal Model of Benign Prostatic Hyperplasia

  • Choi, Young-Jin;Fan, Meiqi;Tang, Yujiao;Iwasa, Masahiro;Han, Kwon-Il;Lee, Hongchan;Hwang, Ji-Young;Lee, Bokyung;Kim, Eun-Kyung
    • Journal of Microbiology and Biotechnology
    • /
    • v.31 no.8
    • /
    • pp.1134-1143
    • /
    • 2021
  • In the present study, we investigated the inhibitory effect of heat-killed Enterococcus faecalis (E. faecalis) and live E. faecalis on benign prostatic hyperplasia (BPH). The BPH rat model was established by administering male rats with testosterone propionate (TP, 5 mg/kg, in corn oil) via subcutaneous injections daily for four weeks after castration. The rats were divided into five groups: Con, corn oil-injected (s.c.) + DW administration; BPH, TP (5 mg/kg, s.c.) + DW administration; BPH+K_EF, TP (5 mg/kg, s.c.) + heat-killed E. faecalis (7.5 × 1012 CFU/g, 2.21 mg/kg) administration; BPH+L_EF, TP (5 mg/kg, s.c.) + live E. faecalis (1 × 1011 CFU/g, 166 mg/kg) administration; BPH+Fi, TP (5 mg/kg, s.c.) + finasteride (1 mg/kg) administration. In both of BPH+K_EF and BPH+L_EF groups, the prostate weight decreased and histological changes due to TP treatment recovered to the level of the Con group. Both of these groups also showed regulation of androgen-signaling factors, growth factors, and apoptosis-related factors in prostate tissue. E. faecalis exhibited an inhibitory effect on benign prostatic hyperplasia, and even heat-killed E. faecalis showed similar efficacy on the live cells in the BPH rat model. As the first investigation into the effect of heat-killed and live E. faecalis on BPH, our study suggests that heat-killed E. faecalis might be a food additive candidate for use in various foods, regardless of heat processing.

A Study on Carbon Footprint and Mitigation for Low Carbon Apple Production using Life Cycle Assessment (전과정평가법을 이용한 사과의 탄소발생량 산정과 저감 연구)

  • Lee, Deog Bae;Jung, Sun Chul;So, Kyu Ho;Kim, Gun Yeob;Jeong, Hyun Cheol
    • Journal of Climate Change Research
    • /
    • v.5 no.3
    • /
    • pp.189-197
    • /
    • 2014
  • Carbon footprint of apple was a sum of $CO_2$ emission in the step of manufacturing waste of agri-materials, and greenhouse gas emission during apple cultivation. Input amount of agri-materials was calculated on 2007 Income reference of Apple by Rural Development Administration. Emission factor of each agri- materials was based on domestic data and Ecoinvent data. $N_2O$ emission factor was based on 1996 IPCC guideline. Carbon dioxide was emitted 0.64 kg $CO_2$ to produce 1 kg apple fruit, and carbon dioxide was emitted 43.6% in the step of the manufacturing byproduct fertilizer, 1.3% in the step of the manufacturing single fertilizer, 4.7% in the step of the manufacturing composite fertilizer, 6.3% in the step of the manufacturing agri-chemicals, 14.6% in the step of the manufacturing fuel, 11.5% in the step of the fuel combustion, 17.7% of $N_2O$ emission by nitrogen application and 0.18% of disposal of agri-materials. It is needed for farmers to use fertilization recommendation based on soil testing (soil. rda.go.kr) because scientific fertilization is a major tools to reduce carbon dioxide of apple production. The fertilization recommendation could be also basic data in Measurable-ReporTablele-Verifiable (MRV) system for carbon footprint.

Effects of Aged Platycodon grandiflorum on Cyclophosphamide-induced Immunosuppression in Mice (홍도라지 추출물이 마우스 모델에서 Cyclophosphamide에 의한 면역력 저하 억제에 미치는 영향)

  • Lee, Eun Byeol;Choi, Ji-Hye;Jang, Hwan-Hee;Hong, Ha-Cheol;Lee, Hae-Jeung;Jeong, Hyun Cheol;Lee, Sung-Jin;Lee, Sung Hyen
    • Korean Journal of Pharmacognosy
    • /
    • v.51 no.4
    • /
    • pp.340-348
    • /
    • 2020
  • This study was conducted to evaluate the immunomodulatory effects of red doraji (Platycodon grandiflorum, RD) prepared by repeated steaming and drying process in the immune-suppressed mice induced by pre (RD-A) or post-treatment (RD-B) with cyclophosphamide. The immune-stimulating effects of ethanol RD extract in in vivo at 150 (RD-1) and 300 mg/kg body weight (RD-2) for RD-A and RD-B groups were measured and compared to the NC group supplied with distilled water only or positive control group. After 14 days of oral supplement, serum IgA, IgG, and cytokine levels, splenocytes proliferation rate, NK cell activity, and gene expression of cytokines were measured as immune related biomarkers. Serum IgA, IgG, IL-1β, and IL-12 levels increased in both RD-A and RD-B groups while serum TNF-α level decreased in RD-A group compared to the NC group. Splenocytes proliferation rate, NK cell activity, and cytokine (IL-1β, IL-6, IFN-γ) expression levels were also improved by RD supplement in the both groups. The RD showed more significant immunomodulatory effects at higher dose (RD-2) rather than the lower dose (RD-1). Thus, RD has an immune efficacy in a dose dependent manner and can be used as an immune stimulating source to improve immunity.

Snapshot View of Expressed Sequences from Brassica rapa

  • Lim, Myung-Ho;Kim, Jin-A;Lee, Ji-Young;Park, Yang-Sun;Lee, Soo-In;Kim, Jung-Sun;Kim, Seog-Hyung;Kwon, Soo-Jin;Lim, Ki-Byung;Yang, Tae-Jin;Jin, Min-A;Park, Kie-Jung;Chung, Yong-Yoon;Lim, Chae-Oh;Hur, Yoon-Kang;Kim, Ho-Il;Park, Beom-Seok
    • Proceedings of the Korean Society of Plant Biotechnology Conference
    • /
    • 2005.04a
    • /
    • pp.199-199
    • /
    • 2005
  • PDF

Analysis of Total Hospital Charges, Length of Stay, and Cost of Rehabilitation by Hospital and Stroke Type (의료기관별 뇌졸중 유형에 따른 진료비, 재원일수 이학요법료의 차이분석)

  • Kim, Sun-Mi;Kim, Da-Yang;Lee, Kwang-Soo
    • The Korean Journal of Health Service Management
    • /
    • v.11 no.1
    • /
    • pp.91-105
    • /
    • 2017
  • Objectives : This study analyzed the differences in length of stay(LoS), total hospital charges(THC), and cost of rehabilitation(CoR) between two types of stroke patients, intracerebral hemorrhage(ICH) and cerebral infarction(CI). Factors associated with these differences were also assessed. Methods : Data were obtained from the 2011 National Inpatient Sample data of Health Insurance Review and Assessment Service. We used propensity score matching to match the characteristics of the two types of stroke patients, and conducted a regression analysis to analyze their associations. Results : The differences between THC, LoS, and CoR by stroke and hospital types were shown. Each type of hospital showed different results. Conclusions : A rapidly aging population will accelerate the number of stroke patients requiring effective management. Studies evaluating healthcare utilization of stroke patients will provide evidence for both healthcare resources allocation and healthcare policy decisions.

Regulatory View of Point on Health Functional Foods in Korea, Japan, and China

  • Jeong, Jeong-Suk;Kim, Sung-Chull;Jeong, Choon-Sik
    • Natural Product Sciences
    • /
    • v.10 no.6
    • /
    • pp.310-314
    • /
    • 2004
  • This is the re-arrangement of the 2004 Asia Nutrition & Dietary Supplement Conference organized by ABF(The Asia Business Forum) in Singapore, especially regulatory view of point of health functional foods for Korea, Japan, and China. Foods that may have health benefits beyond the traditional nutrients that they contain are often called 'Functional Foods'. The concept of functional foods has become popular in recent years, first in Japan and later in other countries, including the USA. In USA, The functional foods was controlled by ACSH (the American Council on Science and Health). In Korea, 'Functional Foods'. was defined on the 'The Law for the Health Functional Foods'(Law No. 6727 : effective as of $26^{th}$, Aug. 2002). KFDA(Korea Food and Drug Administration) is the only authority body for approval, advertisement and claims for the Health Functional Foods in Korea. In Japan, the Japan Health Food and Nutrition Food Association controls the approval, regulate functional foods' advertisement and claims under the name of FOSHU (Foods for Specified Health Uses). In China, the State Food and Drug Administration(SFDA) is the only authoritative organization for the application, supervision and administration of health related products. Asia, especially Korea, Japan and China, is one of the leader in the vitamins and dietary supplement(VDS) market. Regulatory issues on restrictions are the most important how to tap into the health functional foods market including Korea.

Purification and Characterization of Myristoyl-Acyl Carrier Protein Thioesterase from Iris tectorum

  • Kang, Han-Chul;Cho, Kang-Jin;Hwang, Young-Soo
    • Applied Biological Chemistry
    • /
    • v.41 no.4
    • /
    • pp.235-240
    • /
    • 1998
  • The myristoyl-acyl carrier protein (ACP) specific thioesterase from Iris tectorum was purified to a considerable homogeneity and characterized. The enzyme was eluted with a considerable stability by double-gradients using Triton X-100 and low ionic KCl or Na-phosphate through DEAE-52, Octyl-Sepharose, Q-Sepharose, and hydroxyapatite chromatoraphy. SDS-PAGE analysis showed a single band of 39 kDa. The native molecular weight was estimated to be 82 kDa by Sephacryl S-200 chromatography, indicating that the enzyme was a dimer. The thioesterase showed a chain-length specificity to myristoyl-ACP in preference to other-ACPs. The enzyme activity decreased by 1.0 mM myristate to about 27% of the original activity, whereas the remaining activity with decanoate was about 90%. The purified thioesterase was inhibited by myristoyl-CoA more than by myristate, suggesting that the myristoyl-AGP thiolesterase might be controlled by myristic acid and/or a subsequent product myristoyl-CoA. In addition, some biochemical characteristics of the enzyme were described.

  • PDF