• Journal of muscle and joint health
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• v.6 no.1
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• pp.73-84
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• 1999

This study was conducted to identify the characteristics of fatigue and its influencing factors in patients having chronic arthritis. The subjects of this study were 120 patients who visited a Rheumatis Center of H University Hospital. Data were collected from Aug. 9, 1997 to Feb. 5, 1998. For analysing data, SPSS/Win was used for descriptive statistics & Pearson's correlation coefficient, and Lisrel 8.0 was for path analysis. The findings were as follows : 1. Mean score of subjective fatigue was 5.36 and it means moderate degree of fatigue. 2. Fatigue showed positive relationship with pain & depression, and it showed negative relationship with ADL & self efficacy. 3. Fatigue was influenced by pain and depression. and was not influenced by ADL and self efficacy directly. But ADL and self efficacy influenced on fatigue through pain and depression indirectly. According to this findings. the significant influencing factors of fatigue were pain and depression, therefore the development of nursing intervention for relieving pain and depression would be needed.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.3
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• pp.127-133
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• 2019

PURPOSE: The aim of this study was to obtain detailed and quantified data concerning the effects of plantarflexor fatigue induced to the non-paretic side on muscle activities of the bilateral lower extremities during walking in chronic stroke patients. METHODS: In this study, chronic stroke patients were evaluated for six months after the onset of stroke. To induce the non-paretic plantarflexor fatigue, 20 chronic stroke patients were asked to perform their given fatigue affecting assignments, which were presented in a forced contraction fatigue test method, until the range of motion of the plantarflexor was reduced to less than 50%. The muscle activities of the rectus femoris, tibialis anterior and gastrocnemius in the paretic and non-paretic lower extremities were measured using a wireless surface EMG before and after muscle fatigue induction. RESULTS: The findings showed that after plantarflexor fatigue was induced on the non-paretic side, a significant decrease in muscle activities of the rectus femoris on the paretic side was noted (p<.05). The muscle activities of the tibialis anterior and gastrocnemius were also observed to decrease, but, these results were not statistically significant (p>.05). In the non-paretic side, there was a significantly decrease in the muscle activities of the rectus femoris, tibialis anterior, and gastrocnemius (p<.05). CONCLUSION: These finding suggest that the muscle fatigue of the non-paretic plantarflexor affects not only the muscle activity of the ipsilateral lower extremity but also the muscles activity of the contralateral lower extremity. This highlights the necessity of performing exercise or training programs that do not cause muscle fatigue in clinical aspects.

• The Journal of Korean Medicine
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• v.21 no.4
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• pp.55-63
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• 2000

Objectives : Fatigue is a common symptom experienced by everyone. Nevertheless, clinicians have a tendency of ignoring it since fatigue itself is not considered a distinct disease. Actually, some limited research about chronic fatigue syndrome has been made within the country, but in reality, the probability of getting this syndrome is still considered very low due to the strict diagnosis standard. Therefore, there are tremendous numbers of patients who do not get enough attention from clinicians for their fatigue symptoms only because technically they do not belong to the syndrome. Therefore, a basic statistical database must be compiled and patient management programs must be developed. To accomplish this, we conducted this study by measuring degree of fatigue, clinical characteristics and processes of Oriental medical treatment of fatigue patients. Methods : The objects of this study were selected from the new patients who entered the tonification Clinic in Kynnghee Oriental Medical Center between August 11, 2000 and October 7, 2000. Their main complaint was fatigue and they did not suffer from any physical or mental problem either historically or at the time of the study. The objects were divided into two groups based on duration of fatigue; fatigue under 6 months is considered as acute fatigue and fatigue for longer than 6 months is chronic fatigue. The prepared survey sheet for measuring fatigue degree was distributed to the patients with their consent. The patients were divided again into three subgroups : the fIrst group went through 1st test and constitution test after tonification clinic; the second one went into constitution test skipping Ist measuring test; the third one went into only tonification clinic with neither 1st measuring test nor constitution test. Results : The total number of object patients was 47 and 80% of them were considered as 'fatigue patients' by the Chalder scale. Among all patients, 29.5% requested treatment for chronic fatigue, which is over 6 months. The average of scale II for all patients was 14.8, which indicates moderate fatigue. The averages of scale II-1, II-2, II-3 were respectively 7.5, 5.9, and 3.7 so the most common complaint was physical fatigue. When compared scale II based on occupations, student group scored 6.9 and office man group scored 8.5 in scale II-1, physical fatigue, but it was not significant. Conclusions : Numerous number of patients have come to Oriental medical centers or hospitals in Korea. Therefore, deeper statistical research and follow-up-monitoring are reqnired in the Oriental medical academic world. In this study, among all patients who entered the tonification Clinic in Kyunghee Oriental Medical Center, 29.5% requested treatment for chronic fatigue, which is over 6 months. This kind of statistical report is the first time trial in the Oriental medical academy world. Through these steps, more objective treatment can be made and standards of prognosis assessment can be established.tablished.

• The Korean Journal of Rehabilitation Nursing
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• v.8 no.2
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• pp.110-118
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• 2005

Purpose: The purpose of this study is to understand the level of fatigue and daily living activities and to confirm their relationship in patients with chronic liver disease. Method: The sample consisted of 182 patients with chronic liver disease with a mean age of 42.4 years, who visited the D University Hospital and a S clinic from February, 2004 to March in 2004. Data were collected by a self reporting questionnaire on the selected variables such as fatigue and daily life activities. Collected data were analyzed by using SPSS program for descriptive statistics, Pearson's correlation coefficients, t-test, ANOVA. Results: Subjects showed the mild level of fatigue and slightly high level of daily living activities. They also showed a negative relationship between fatigue and daily living activities. Conclusion: It is necessary to develop nursing intervention program to reduce the level of fatigue for improving the level of daily living activities in patients with chronic liver disease.

• Journal of Acupuncture Research
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• v.39 no.3
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• pp.170-181
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• 2022

This review evaluated the efficacy of electroacupuncture (EA) for chronic fatigue syndrome. Randomized controlled trials (RCTs) using EA as an intervention for patients with chronic fatigue syndrome were identified in 6 databases (PUBMED, EMBASE, CNKI, J-STAGE, KMBASE, OASIS). Fatigue indicators were used as the primary outcome measures. The quality-of-life index, efficiency rate, and level of pain were used as secondary outcome measures. There were 408 patients from seven RCTs included in this study. Meta-analysis showed that EA was significantly associated with fatigue relief compared with the control group (n = 141 SMD = -1.55, 95% CI; -2.58 - -0.52, p = 0.003, I² = 92%). In addition, EA had a statistically significant improvement in quality of life compared with the control group (n = 176, SMD = -2.29, 95% CI; -3.68 - -0.90, p = 0.001, I² = 96%). One study reported ten cases of bleeding, however, no serious adverse events were reported in any of the included studies. This review determined that EA may have a greater clinical effect than the control group for fatigue relief and improved quality of life. However, there were several risks of bias identified. Not all of the RCTs accurately reported the research method, all studies were conducted in 1 country (China), and the number of studies included were small.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.2
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• pp.126-133
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• 2018

The aim of this survey is to investigate the current state of pattern identification, treatment and management on chronic fatigue in the Korean medicine. From May 25, 2017 to June 7, we distributed contents of questionnaires to 17,992 Korean medical doctors via e-mail, and then received answers from 329 people. The surveys were conducted by a specialized research organizations. Researchers were blinded to the participant's personally identifiable information or whether they participated in the investigation. In Korea, almost Korean medicine doctors (94.5%) used pattern identification in the treatment of chronic fatigue patients. The main diagnostic methods were visceral (38.5%), qi-blood-fluid-humor (32.3%), and sasang constitutional pattern identification (14.3%). The high-frequent therapy were herbal medicine (37.0%), acupuncture (27.9%), moxibustion (11.7%), and cupping (8.6%). The primary goals of treatment were Improvement and relaxation of stress condition (18.1%), improvement of quality of life (13.1%), increase of functional vitality (34.0%), and fatigue management (23.3%). The key factors affecting treatment outcomes were the patient's aggressiveness in treatment (23.5%) and his/her lifestyle and environment(22.7%). This study was a pioneering research for chronic fatigue on the aspect of medical service provider in the Korean medicine. We hope that this study can be used as a basis for developing a more appropriate and reasonable practice guidelines for chronic fatigue.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.492-496
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• 2004

This research was carried out to examine the correlation between the patients of functional dyspepsia and four constitution (Sasang Constitution). This research examined the correlation of functional dyspepsia versus Sasang Constitution, chronic fatigue, and mental stress in 100 cases of functional dyspepsia. No significant correlation was witnessed between average duration of dyspepsia and gender, and smorking. There was tendency of increased duration of indigestion in relation with length of chronic fatigue and the degree of mental stress. Significant difference was found between the patients with indigestion and Sasang Constitution types. Soeumin among the patients with indigestion were numerous and it was significantly different with normal people. Significant correlation was found between the period of indigestion and chronic fatigue and the degree of mental stress. Significant difference was found between the patients with indigestion and Sasang Constitution types.

• The Journal of Korean Medicine
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• v.37 no.2
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• pp.76-84
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• 2016

Objectives: We evaluated the anti-fatigue effects of Rh2-enriched Korean ginseng (Ginseng Rh2+) using a forced exercise-induced chronic fatigue mouse model. Methods: ICR male mice were subjected to running wheel for 1 h, 5 days/week during 4 weeks, and running velocity was gradually increased. Each running session was followed by oral administration of distilled water, Ginseng Rh2+ (150 or 300 mg/kg), or N-acetyl-L-cysteine (NAC, 100 mg/kg) 1 h later. The exercise tolerance and forced swimming test were performed to evaluate the fatigue condition. Results: Chronic forced exercise reduced the physical activity, as evidenced by the behavioral tests, which were notably ameliorated by Ginseng Rh2+ treatment. Ginseng Rh2+ treatment also attenuated the alterations of energy metabolism and oxidative stress in skeletal muscle tissues and/or sera, including malondialdehyde (MDA), lactate concentration and its related factors (lactate dehydrogenase, blood urea nitrogen, and glucose levels). Conclusion: These findings strongly suggest that Ginseng Rh2+ exerts a potent anti-fatigue effect through modulation of energy metabolism and oxidative response.

• The Journal of Korean Medicine
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• v.32 no.6
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• pp.67-73
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• 2011

Objectives: To examine the overview of fatigue-related health conditions in the Korean general population. Methods: Data were collected from 2,203 adults (1,126 men and 1,077 women) via a self-reporting questionnaire and their sleeping, exercise, stress, physical problems, use of functional food, and fatigue status were analyzed. Results: The average sleeping hours was about $6.6{\pm}2.0$ hrs per day, and 24.3% of subjects didn't exercise (over 30 min) in a week. Around 16.5% of subjects were under severe stress, and 46.1% (36.9% male vs. 55.6% female) had had trouble with at least one form of physical distress including dyspepsia, headache or muscular pain. 45.4% (37.2% male vs. 53.9% female) of subjects used functional supplements. 46.3% (42.8% male vs. 50.0% female) of subjects complained of chronic fatigue, and they were significantly different compared with no-fatigue subjects regarding severe stress status (8.6% vs. 24.0%), frequency of physical distress (33.2% vs. 69.9%), and use of functional supplements (41.6% vs. 49.8%). Conclusion: This result first reports the features of fatigue-related health conditions including prevalence of chronic fatigue in the Korean population. This data could be helpful to develop fatigue-focused traditional Korean medicine in the future.

• The Journal of Korean Medicine
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• v.33 no.4
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• pp.81-85
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• 2012

Objectives: To describe a clinical case of a patient with chronic fatigue syndrome (CFS) who was cured using indirect moxibustion. Methods: A male patient with severe CFS was treated with mainly indirect moxibustion (KI1, CV4 and CV8). The clinical outcome was observed by self-reporting, both visual analogue scale (VAS) and numerical rating scale (NRS). Results: The patient's symptoms matched the criteria for CFS diagnosis. His symptom differentiation was the "Yang deficiency of spleen and kidney". The fatigue feeling and related-symptoms were radically reduced by 14-day treatment. The VAS and NRS score changed from 8.5 and 70 to 3.5 and 35, respectively. Conclusions: This case report provides information on the potential of moxibustion therapy and its application for CFS and fatigue-associated disorders.