• 대한한방내과학회지
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• 제24권2호
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• pp.329-336
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• 2003

Objective : We evaluated the therapeutic effect of Banwhasasimtang dry extract powder on gastrointestinal symptoms and its side effects in patients with functional dyspepsia. Methods : Patients with functional dyspepsia, defined as discomfort in the epigastrium. A total 45 patients participated in this study. Dyspeptic symptoms ratio was obtained by patients, total point of symptom score/total 21 points x 100(%). On each of symptom after 4 weeks administration of Banwhasashim-tang was made by variation of symptom score: If symptoms score of posttreatment is lower than that of pretreatment, it is improved ; Otherwise aggravated, and if there is no change between them, unchangeable. When a full health condition of normal control is assumed 100%, relative health condition of dyspeptic patient could be calculated from 'full health condition-dyspeptic symptoms ratio'. Therefore a whole satisfaction rate on symptom improvement was presented with variation of a relative health condition to dyspepsia between pretreatment and post. Results : Banwhasashimtang significantly improved symptoms in patients. The significance was shown in both all seven items(p<0.01, respectively) and 19.2% (p<0.01) of increase of a whole satisfaction rate on symptom improvement. There is no remarkable side-effect in all laboratory test, excepting 1 case of abdominal pain and another one case of recurred pain of chronic prostatitis. Conclusion : Banwhasashimtang extract provides symptomatic relief in functional dyspepsia and is no remarkable side-effect drug.

• 한방재활의학과학회지
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• 제21권2호
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• pp.211-226
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• 2011

Objectives : The purpose of this study is to establish literatural evidence about traditional Korean medical physiotherapy through literatural review. Methods : Applicable paragraphs which were related to the traditional Korean medical physiotherapy were phrased from in "Hwang-je-nae-gyung(黃帝內經)", "Yumun-sa-chin(儒門事親)", "Geum-guei-yo-ryack(金匱要略)", "Eui-hack-ip-mun(醫學入門)", "Gyung-ack-jeon-seo(景岳全書)", "Eui-hack-gang-mock(醫學綱目)", "Dong-eui-bo-gam(東醫寶鑑)" where were archiving of Oriental or Korean medicine literatures. Searched paragraphs were analysed for establishing historical and theoretical bases of Korean medical physiotherapy. Results : 1. Theromtherapy is originated from yu(熨), hot hand, warm, water bath, warm earth, fumigation, lamp, torchlight and brazier. Matching indications are various musculoskeletal pain and diseases, skin diseases such as chronic inflammation, frostbite, gynecological and urogenital diseases such as uterine myoma, lower abdominal pain, metrorrhagia, breast diseases, digestive tract diseases such as vomiting, diarrhea, stomachache and also it treats cardiovascular disease. Other matching indications are sunstroke, rhinorrhea, psycosis and anal pain. And it used helping acupuncture therapy. 2. Cryotherapy is originated from lengfu(冷敷), lengtie(冷貼), cold stone and cold water. Matching indications are various fever disease, skin diseases such as acute inflammation, wound, fever skin disease, otorhinolaryngological diseases such as acute sore throat, otitis, stomatitis, nasal bleeding and contusions, abrasions, burn and dysuria. In addition, it treats extremity coldness, chillness, stomachache caused to accumulate fever. 3. Physiotherapy by circulating meridian system is originated from manipulation such as pushing, massage and beating to therapy point. Matching indications are musculoskeletal diseases such as various muscular pain, heavy sensation, convulsion, urogenital diseases such as dysuria, lower abdomen pain, digestive tract diseases such as stomachache, and paralysis due to blocked meridian system. And other matching indications are psycosis, leprosy, hypoesthesia, acute stroke. In addition it helps other therapy methods. In addition, the power of manipulation classify to strengthen and reduce. 4. Physiotherapy by balancing meridian system is originated from sunshine, magnet, horn, bamboo and tube. Sunshine helps improving self's care and cure inflammatory skin disease. Magnet's matching indications are paralysis, various injuries, abscess, fever and eye disease. Cupping therapy treats to skin diseases and internal diseases such as tuberculosis. Conclusions : Traditional Korean medical physiotherapy was widely used in traditional Korean medicine since ancient time based on the traditional Korean medical principle and anatomical knowledge. With modern physiotherapy and traditional Korean medicine together, effects of treatment are enhanced. And traditional Korean medical physiotherapy is appropriated to world physiotherapy's expectation.

• Clinical and Experimental Pediatrics
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• 제51권4호
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• pp.391-395
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• 2008

목 적 : 만성기능성 변비소아의 분변박힘제거 단계에서 전해질이 함유지 않은 PEG 4000의 적절한 용량, 효과 및 안전성에 대한 연구를 시행하였다. 방 법 : 2004년 3월부터 2006년 8월까지 건국대학교병원 소아과에서 만성기능성 변비로 진단된 환아 86명을 대상으로 전향적으로 시행하였으며, 주증상의 완화, 배변횟수와 배변 용이함의 향상, 복부 X선 검사 상 대변양의 감소 가운데 2가지를 충족하면 분변박힘제거가 성공적인 것으로 판단하였다. 치료효과를 판정하기위해 보호자나 환아가 기록한 변비 일지를 바탕으로 PEG 4000 복용전과 복용후의 주증상, 평균 배변횟수, 변의 굳기 및 단순 복부 X-선 사진을 비교하였으며, 임상적 증상 관찰과 함께 일반혈액검사와 전해질 검사, 칼슘, 마그네슘, 혈청삼투압검사를 시행하여 부작용을 확인하였다. 결 과 : 연구를 마친 83명 가운데 82명에서 분변박힘제거에 성공하였으며(99%), 분변박힘제거에 필요한 전해질이 함유되지 않은 PEG 4000의 평균용량은 $0.93{\pm}0.28g/kg/day$ (0.4-2.0 g/kg/day, 최대용량 30 g/day)이었다. 배변횟수는 83명 가운데 79명의 환아에서 치료 후에 배변횟수가 증가되었으며(평균 배변횟수 $5.02{\pm}2.71$회/1주 vs. $11.25{\pm}5.43$회/1주), 배변도 수월하고, 주증상도 거의 모든 환자에서 호전되었다. 치료 전후의 단순 복부 X-선 사진을 비교하였을 때, 통계학적으로 의미 있게 호전된 소견을 보였다(P=0.0007). 임상적으로 두드러기 1명, 심한 설사 1명과 설사와 복통 1명, 총 3명이 치료를 마치지 못하였으며, 대상 군에서는 손발 저림 증상이 1명에서 나타났으나, 약제 중단 후 아무런 처치 없이 호전되었다(4/86=4.7%). 검사소견상 1명에서 고삼투압혈증이 관찰되었으나, 임상적으로 증상이 관찰되지 않았으며, 6명에서 호산구 증가가 관찰되었다. 결 론 : 만성 기능성변비환아의 분변박힘제거에 안전하고 효과적인 PEG 4000 용량은 $0.93{\pm}0.28g/kg/day$ (최대용량 30 g/ day)로 생각된다.

• 동의생리병리학회지
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• 제19권2호
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• pp.544-548
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• 2005

I studied on the influence of BUDDEUMI(moxa and cupping a boil) in the live blood condition and the favorable turn up a subjective symptom of chronic irritable bowel syndrome patient. The results are as follows : After the perform of BUDDEUMI, in the Erythrocyte Aggregation, the efficiency is 87%(3persons decrease and 10 persons destroy/15 persons). In the Rouleau, the efficiency is 78%(2persons decrease and 5 persons destroy/9 persons). In the Target Cells, the efficiency is 90%(3persons decrease and 6 persons destroy/10 persons). In the Ovalocytes, the efficiency is 88%(3persons decrease and 4 persons destroy/8 persons). In the Poikilocytes, the efficiency is 76%(1persons decrease and 2 persons destroy/4 persons). After the perform of BUDDEUMI, in the Cholesterol Crystals, the efficiency is 82%(3persons decrease and 6 persons destroy/11 persons). In the Atherosclerotic Plaque, the efficiency is 80%(2persons decrease and 2 persons destroy/5 persons). In the Chylous, the efficiency is 86%(3persons decrease and 9 persons destroy/14 persons). On the favorable turn up a subjective symptom, the efficiency of symptom of appetite and digestion is 91%(5persons turn up exceedingly favorable, 9 persons turn up favorable, 7 persons turn up good, 2 persons turn up invalid / 23persons). In the efficiency of symptom of fatigue and feeble is 85%(3persons turn up exceedingly favorable, 6 persons turn up favorable, 8 persons turn up good, 3 persons turn up invalid / 20persons). And the efficiency of symptom of abdominal swelling and displeasure is 88%(2persons turn up exceedingly favorable, 10 persons turn up favorable, 8 persons turn up good, 3 persons turn up invalid / 24persons). In the efficiency of symptom of abdominal pain is 88%(4persons turn up exceedingly favorable, 10 persons turn up favorable, 8 persons turn up good, 3 persons turn up invalid / 25persons). The efficiency of symptom of constipation and diarrhoea is 90%(5persons turn up exceedingly favorable, 9 persons turn up favorable, 6 persons turn up good, 2 persons turn up invalid / 22persons).

• Advances in pediatric surgery
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• 제16권2호
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• pp.126-133
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• 2010

Malrotation is a congenital anomaly that becomes symptomatic more frequently during infancy. The indication for surgical treatment at that age is straightforward. In older children, the diagnosis may be more difficult because of chronic and vague complaint. The aim of this study is to compare the symptoms, rate of volvulus and surgical findings in children younger and older than one year. A retrospective study of 40 patients in a a single medical center diagnosed with malrotation from April 1996 to May 2010 was performed. There were 20 (50 %) boys and 20 (50 %) girls. At the time of operation, 27 (67.5 %) patients were younger and 13 (32.5 %) were older than 1 year. Vomiting was seen in 20 cases (74.1 %) of the younger group compared to 2 cases (15.4 %) of the older group. Abdominal sonography and upper gastrointestinal series showed a sensitivity of 100%. Operative findings: 12 (44.4 %) of the younger group presented with volvulus compared to none of the older group. The Ladd's procedure was routinely performed with appendectomy in all cases and bowel resection was requires when volvulus included bowel necrosis or other anomalies were found. After definite procedures, surgical correction for adhesive obstruction was necessary in 5 menbers (18.5 %) of the younger group and 1 patient (7.7 %) in the older group. There was 1 death due to respiratory failure and pneumonia. Abdominal pain was more frequent symptom and bilious vomiting was less frequent. Volvulus did not occur in the older group. Malrotation should be diagnosed promptly in children over 1 year of age by upper gastrointestinal series and abdominal ultrasonography even though symptoms are not as clear cut as in infants.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제8권1호
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• pp.12-20
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• 2005

목 적: 급성 및 만성 복통 혹은 상부 위장관 출혈로 병원에 와서 상부 위장관 내시경술을 시행하여 H. pylori 감염이 확인된 환아의 내시경적 소견에 대해 알아보고 H. pylori 박멸 치료를 위해 사용한 omeprazole, amoxicillin, clarithromycin의 삼제 병합 요법을 1주 및 2주 투여군으로 나누어 그 제균 효과를 비교해 보고자 하였다. 방 법: H. pylori 감염의 진단은 상부위장관 내시경술(GIF-XQ240, Olympus, Tokyo, Japan)을 시행하여 위전정부와 위체부에서 2개씩의 조직을 얻어 CLO (Delta West, Bentley, Australia)검사와 조직학적 검사를 하여 양성이면 H. pylori에 감염된 것으로 판정하였다. 요소 분해 효소 검사는 실온 상태에서 CLO 키트에 생검 조직을 넣고 24시간까지 관찰하여 색이 노란색에서 적색으로 변하면 양성, 조직학적 검사는 Hematoxylin & Eosin 염색 표본을 시행 후 내시경 검사 결과를 모르는 한 명의 병리의가 현미경상 위 점막 조직에서 균이 관찰되면 양성으로 판정하였으며 이 중 하나 이상에서 양성인 경우 H. pylori 양성으로 진단하였다. H. pylori 감염이 확인된 환아들을 치료기간에 따라 두 개의 군으로 구분하여 제I군은 omeprazole (1 mg/kg/day, 최대 20 mg, bid), amoxicillin (50 mg/kg/day, 최대 1g, bid), clarithromycin (15 mg/kg/day, 최대 500 mg, bid)의 삼제 병합요법으로 1주간, 제II군은 같은 약제로 2주간 치료하였다. 치료 종료 4주 후에 4시간 이상 금식 후에 100 mg $^{13}C$-요소분말을 사용한 $^{13}C$-요소 호기 검사(IR300, OTSUKA electronics, Osaka, Japan)를 시행하여 음성인 경우 박멸이 성공한 것으로 하였고 요소 호기 검사에서 양성인 경우에는 같은 약제 또는 bismuth, metronidazole과 amoxicillin으로 추가 치료를 하였다. 결 과: H. pylori 양성 환아의 내시경 소견은 결절성 위염이 26명(43.3%)으로 가장 많았고 미란성 위염 10명(16.7%), 출혈성 위염 7명(11.7%), 위궤양 2명(3.3%), 정상 소견 15명(25.0%)이었다. Omeprazole, amoxicillin, clarithromycin (OAC) 삼제요법으로 1주간 치료한 제I군에서 치료 종료 4주 후 시행한 $^{13}C$-요소 호기 검사에서 30명 중 26명(86.7%)에서 음성 반응을, 4명(13.7%)에서 양성 반응을 보였다. 2주간 치료한 제II군에서도 치료 종료 4주 후 시행한 $^{13}C$-요소 호기 검사에서 30명 중 26명(86.7%)에서 음성 반응을, 4명(13.7%)에서 양성 반응을 보였다. 두 군 모두에서 H. pylori 박멸률은 86.7%였으며 두 군 사이에서 통계적으로 유의한 차이는 없었다. H. pylori 제균에 실패한 경우 제 I군에서 $^{13}C$-요소 호기 검사에서 양성 반응을 보인 4명의 환아를 bismuth, amoxicillin, metronidazole로 1주간 추가 치료를 하였고 4주 후 시행한 $^{13}C$-요소 호기 검사에서 모두 음성 반응을 보였다. 제II군에서 $^{13}C$-요소 호기 검사에서 양성 반응을 보인 4명의 환아 중 1명은 같은 약제로, 3명은 bismuth, amoxicillin, metronidazole로 1주간 추가 치료를 하였고 4주 후 시행한 $^{13}C$-요소호기 검사에서 모두 음성 반응을 보였다. $^{13}C$-요소호기검사에서 음성 반응을 보인 모든 환아에서 임상 증상은 완전히 소실되거나 호전되었다. 결 론: 소아에서 급성 및 만성 복통, 위장관 출혈과 H. pylori 감염간의 연관관계에 대하여는 논 란이 많으나 H. pylori 감염이 원인이 될 수 있으며 균 박멸을 위한 치료가 필요하다고 생각한다. 저자들의 연구에서 상부 위장관 증세를 가진 H. pylori 감염 환아에 대한 내시경 소견은 결절성 위염이 43.3%로 가장 많이 관찰되었으며 이것은 다른 연구들에서와 마차가지로 H. pylori 양성 환아들의 특징적인 소견으로 생각된다. 소아 H. pylori 감염의 치료에 있어서 omeprazole, amoxicillin, clarithromycin의 삼제 병합 요법의 1주간 치료와 2주간 치료 결과를 비교한 결과, 박멸률은 두 군 모두 86.7%로 두 군 간의 유의한 차이는 없었으며 이것은 성인에서의 85~95%와 유사하였다. 저자들의 연구에서는 omeprazole, amoxicillin, clarithromycin의 1주 치료가 박멸율, 순응도 및 비용면에서 일차 치료로 바람직하리라 생각된다. 향후 H. pylori 감염의 적절한 치료 방법 및 치료 기간에 대한 좀 더 체계적인 연구가 필요할 것이다.

• 한국직업건강간호학회지
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• 제9권1호
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• pp.5-17
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• 2000

The occupational health nursing guideline for primary care was developed by the Korean Academic Society of occupational health nursing and the organization for occupational health nurses (currently known as the Korean Association of Occupational Health Nurses) in 1993. Since then, there have been many changes in the health care environment and job performance of occupational health nurses. Appropriate revisions are necessary of the guidelinea based on this background. The purpose of this study was to describe the use of the occupational health nursing guideline for primary care and to analyze the characteristics of primary care activities by occupational health nurses. The questionnaire was mailed to 150 occupational health nurses(OHNs) with the response rate of 64%. The results can be summarized as follows; 1. 65.6% of OHNs have been using the guideline for primary care and 75.9% of them agreed that the guideline was be helpful for their job. 2. Common symptom care, emergency care and chronic illness care were more frequently implemented than occupational disease care by OHNs. In manufacturing industries, emergency care was more frequently implemented than chronic illness care in contrast to the service industries. 3. Most frequent common symptoms treated by OHNs were indigestion, diarrhea, abdominal pain, headache, and coughing. In the case of chronic illness, OHNs more frequently treated diseases of the gastro-intestinal system, skin and sensory organs, and the respiratory system. Emergency care for bruises, burn, and abrasions was more frequently provided. VDT syndrome was the most common occupational disease cared by OHNs in manufacturing and service industries. 4. OHNs prescribed the medicine for external application more frequently than internal medicine. Remedy for colds, analgesics, vitamins, and digestives were more frequently used. From these results, we suggest that the guideline should be revised to emphasize the activities consisting problem finding such as health assessment, physical examinations, monitoring and screening, and to renew the drug list in the range of over- the counter medication (OTC). In the future, the guideline will include the strategies for the role as the case manager.

• 동의신경정신과학회지
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• 제13권1호
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• pp.127-132
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• 2002

이상의 증례는 해역(咳逆)과 희기(噫氣)가 복합된 난치성 증상이 칠정(七情) 자극에 의하여 유발될 수 있음을 보여주었으며, 치료에 있어서도 약물(藥物)과 침구치료(針灸治療) 뿐만이 아니라 이정변기요법(移情變氣療法), 지언고론요법(至言高論療法), 경자평지료법(驚者平之療法), 가족치료(家族治療) 등 다양한 정신요법 들이 시도되어야만 호전될 수 있음을 보여주었다. 이러한 증례에 있어서 기질적(器質的) 병리변화(病理變化)와 정신적(精神的) 요소(要所)가 어떠한 정도로 관여하는지에 대하여는 향후의 자세한 연구가 필요하리라 사료된다.

• 한국임상수의학회지
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• 제28권4호
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• pp.442-445
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• 2011

Macrocyclic lactone에 저항이 있는 Parascaris equorum은 몇몇 국가에서 보고되었다. 그랜트얼룩말(Equus burchelli bohmi)이 만성체중감소 및 심한 침울로 인하여 제주경마공원동물병원에 내원하였다. 임상검사에서 빈맥 및 탈수가 밝혀졌고 다음날 심한 복통을 앓고 난 후 폐사하였다. 내원하기 전에 얼룩말은 3개월 간격으로 3회에 걸쳐 ivermectin을 경구로 투여 받았고 첫 침울증상 30일 전에도 ivermectin으로 투여 받았다. 부검에서 위와 소장에 회충축적 및 장천공을 확인하였다. 저자들의 지식으로는 성숙한 얼룩말에서 ascarid impaction 및 장천공 예가 매우 드물다. 본 증례의 원인은 P. equorum이 ivermectin에 저항성이 있을 수 도 있다고 의심하고 있다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권2호
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• pp.147-153
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• 2018

Epstein-Barr virus (EBV) infection can be presented with various clinical manifestations and different levels of severity when infected. Infectious mononucleosis, which is most commonly caused by EBV infection in children and adolescents, is a clinical syndrome characterized by fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. But rarely, patients with infectious mononucleosis may present with gastrointestinal symptoms and complicated by gastritis, splenic infarction, and splenic rupture. We encountered a 16-year-old girl who presented with fever, fatigue, and epigastric pain. Splenic infarction and EBV-associated gastritis were diagnosed by using esophagogastroduodenoscopy and abdominal computed tomography. Endoscopy revealed a generalized hyperemic nodular lesion in the stomach, and the biopsy findings were chronic gastritis with erosion and positive in situ hybridization for EBV. As splenic infarction and acute gastritis are rare in infectious mononucleosis and are prone to be overlooked, we must consider these complications when an infectious mononucleosis patient presents with gastrointestinal symptom.