• 제목/요약/키워드: chemicals

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Multiple-end-point Bioassays Using Microorganisms

  • Iwahashi, Hitoshi
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제5권6호
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    • pp.400-406
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    • 2000
  • Since the 1950s, the numbers of species and chemicals produced have significantly increased. Despite the fact that industrial chemicals have given us numerous benefits, there is no doubt that they have damaged the environment. The chemicals being dispersed on the earth should be carefully controlled to prevent adverse effects. Bioassay is one of the methods to assess chemical safety. In bioassay systems, chemical safety is estimated by monitoring biological responses to environmental pollutants and newly synthesized chemicals. This report introduces multiple-point bioassay systems that are based on chemical sensitivities of microorganisms, responses of one kind of organism, and micro-array technology. Multiple-end-point bioassays enable the prediction of chemicals in the environment and the understanding of toxicities of newly synthesized chemicals.

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질소 상압플라즈마를 이용한 TiO2 박막의 표면개질 및 광활성 평가 (Surface Modification of TiO2 Thin Films by N2 Atmospheric Plasma and Evaluation of Photocatalytic Activity)

  • 임경택;김경환;박준;김경석;박유정;송선정;김종호;조동련
    • 공업화학
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    • 제20권4호
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    • pp.402-406
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    • 2009
  • 상압플라즈마 공정을 이용하여 $TiO_2$ 박막의 표면을 개질하고 광촉매 활성을 평가하였다. $TiO_2$ 박막은 $TiO_2$ 졸-겔 용액에서 유리판에 dip-coating법으로 코팅한 후 소성 온도와 소성 시간을 변화시켜 가면서 제조하였다. 표면 개질에 사용된 플라즈마는 질소 플라즈마였으며, 방전전력, 처리시간 등의 공정변수를 변화시키면서 실험을 수행하였다. 광촉매 활성은 UV-A와 형광등 하에서의 메틸렌 블루 분해효율을 바탕으로 평가하였다. XPS 분석 결과, 박막의 표면에 소량의 질소가 도핑되었음을 알 수 있었으며, 광촉매 효율은 UV-A와 형광등 하에서 모두 증가하였고, 특히 형광등 하에서 좀 더 증가하였다.

The Design of Remote Monitoring and Warning System for Dangerous Chemicals Based on CPS

  • Kan, Zhe;Wang, Xiaolei
    • Journal of Information Processing Systems
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    • 제15권3호
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    • pp.632-644
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    • 2019
  • The remote monitoring and warning system for dangerous chemicals is designed with the concept of the Cyber-Physical System (CPS) in this paper. The real-time perception, dynamic control, and information service of major hazards chemicals are realized in this CPS system. The CPS system architecture, the physical layer and the applacation layer, are designed in this paper. The terminal node is mainly composed of the field collectors which complete the data acquisition of sensors and video in the physical layers, and the use of application layer makes CPS system safer and more reliable to monitor the hazardous chemicals. The cloud application layer completes the risk identification and the prediction of the major hazard sources. The early intelligent warning of the major dangerous chemicals is realized and the security risk images are given in the cloud application layer. With the CPS technology, the remote network of hazardous chemicals has been completed, and a major hazard monitoring and accident warning online system is formed. Through the experiment of the terminal node, it can be proved that the terminal node can complete the mass data collection and classify. With this experiment it can be obtained the CPS system is safe and effective. In order to verify feasible, the multi-risk warning based on CPS is simulated, and results show that the system solves the problem of hazardous chemicals enterprises safety management.

사고 누출 화학물질의 지하수 및 토양 환경 내 거동 및 환경 독성 특성 II: 인화성 물질을 중심으로 (Fate and Toxicity of Spilled Chemicals in Groundwater and Soil Environment II: Flammable)

  • 조은혜;신도연
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제23권6호
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    • pp.1-8
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    • 2018
  • In this study, formaldehyde and benzene were selected as the arbitrary chemicals in accidental leakage to environment, and their physicochemical and biological characteristics and toxicity were studied. Also, the fate of these chemicals in soil and groundwater was studied based on the results of previous studies. They can be released into the atmosphere as gas or vapor phase, which then can be photochemically degraded. Since they have relatively high water solubility, they are likely to have high mobility in water and soil. Volatilization of these chemicals from soil is affected by the soil moisture content. Biodegradation of formaldehyde and benzene is one of the important pathways as well. Therefore, it is necessary to study the environmental impacts of leakage accidents of flammable chemicals such as formaldehyde and benzene. Further research on the fate of flammable chemicals in the environment is needed to take appropriate response actions to leakage accidents of flammable chemicals, and this will contribute to the development of practical guidelines to cope with leakage accidents.

화학물질의 효율적 안전관리 방안에 관한 연구 (A Study on the Safety Management Measures Efficient Chemical Substances)

  • 최민기;최돈묵
    • 대한안전경영과학회지
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    • 제15권3호
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    • pp.37-50
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    • 2013
  • It is not an exaggeration to say that modern chemicals take a leading place in our life, and people live with the chemicals, having a huge impact on their daily life. The chemical industry in South Korea, ranked seventh in the world, is one of the key industries that are forming greater part of Korean economy. The actual state of the chemical industries, however, is that over 14 tons of hazardous chemicals are being discharged annually and threaten people's lives with a lack of knowledge of its potential danger. In this way, not only beneficial to us, some of these substances, All chemicals, but also present a threat fundamentally our living environment to hazards to human health and the environment, accidents such chemicals, unlike accidents general understanding the scale of damage and propagation velocity has a complex very difficult risk profile, that can occur during deployment of an accident type is also very diverse. Is the actual situation of public concern against harmful chemicals management's is amplified by the chemical accident in the wake such accidents, government and corporate and reactive system and management system prior to the chemical accident the need for communication to exchange ideas with each other between residents, providing information is important. Therefore, the government departments and corporations, which manage variety of chemicals, ought to contribute toward a development of national security by rigid control over the Hazardous chemicals.

Micronucleus Test for the Classification of Chemical Mutagenicity according to Globally Harmonized System

  • Rim, Kyung-Taek;Kim, Hyeon-Yeong;Chung, Yong-Hyun
    • Journal of Applied Biological Chemistry
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    • 제56권4호
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    • pp.191-197
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    • 2013
  • To classify the chemical hazard according to globally harmonized system of classification and labeling of chemicals (GHS), we investigated the genotoxicity of three chemicals, methyl myristate, 2-ethylhexanoic acid zinc salt, N,N,N',N'-tetrakis(2-hydroxyethyl) ethylenediamine, using male ICR mice bone marrow cells for the screening of micronucleus induction. Although these three chemicals have already been tested numerous times, a micronucleus test has not been conducted. The seven week-old male ICR mice were tested at three dosages for the three chemicals, respectively. After 24 h of oral administration with the three chemicals, the mice were sacrificed and their bone marrow cells were prepared for smearing slides. As a result of counting the micronucleated polychromatic erythrocyte (MNPCE) of 2,000 polychromatic erythrocytes, all treated groups expressed no statistically significant increase of MNPCE compared to the negative control group. There were no clinical signs related with the oral exposure of these three chemicals. It was concluded that these three chemicals did not induce micronucleus in the bone marrow cells of ICR mice, and there was no direct proportion with dosage. These results indicate that the three chemicals have no mutagenic potential under each test condition, and it is not classified these chemicals as mutagens by GHS.

실험실 GC-MS를 이용한 사고대비물질 분석방법 연구 (Study on the analytical method using GC-MS for the accident preparedness substances)

  • 김기준;이진선;이수영;황승률;김영희;석광설
    • 분석과학
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    • 제26권1호
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    • pp.80-85
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    • 2013
  • 본 연구는 유해화학물질관리법에 지정되어 있는 사고대비물질에 대한 실험실적 분석방법을 정립하기 위한 것으로, GC/MS 분석이 가능한 25종 사고대비물질을 대상으로 정량분석을 수행하였다. GC/MS 정량분석결과 69종 사고대비물질 중 산화프로필렌(propylene oxide) 등 21개 물질에 대한 결정계수($r^2$)는 0.998 이상을 보였고, 포스겐(phosgene)의 결정계수는 0.994, 노말-부틸아민(n-butyl amine) 외 1종은 0.987, 에틸렌디아민(ethylene diamine)은 0.958의 결정계수를 보였다. 동일한 GC/MS 분석 조건으로 표준물질을 분석한 결과 총 25종에 대한 검량선이 작성되었다. 현재 사고대비물질에 대한 분석 연구가 필요한 상황에서, 본 연구결과는 화학사고 사후 환경 영향 조사를 위한 정량분석에 도움이 될 것으로 판단된다.