• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.33 no.2
• /
• pp.521-528
• /
• 2013

Urban drainage systems are generally designed as open channel flow. The system, however, shows a partially surcharged flow in its body, especially at junctions or manholes. Thus, a special case of this condition needs to be explained as pressurized flow condition for designing the sewer system. This study considered the surcharged manhole flows during an unexpected rainfall event or an excess of design frequency. Overflows from surcharged manholes and urban flooding can occur from the effect of surcharged flows. Thus, sewer systems should be designed with the concept of open channel flow and pressurized flow. Also, energy losses in a manhole need to be considered. The aim of this study is to develop the numerical model which can evaluate the effect of the energy losses at the manhole. The numerical model was verified and compared with hydraulic model and SWMM. The results showed that the water depth of numerical model was in good agreement with hydraulic model at the each manhole. However, the SWMM underestimated the water depth because that model ignored the energy losses at manholes. Thus, the developed numerical model in this study could be a useful tool for the assessment of a conveyance of urban drainage system.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.25 no.5B
• /
• pp.879-888
• /
• 2000

In this paper, the performance of IS-95B CDMA system adopting multi-code scheme for data service on the forward link is obtained by theoretical analysis and computer simulation. The wireless channel is assumed to include AWGN, MUI(Multi-User Interference), and MPI(Multi-Path Interference), and multipath Rayleigh fading modeled by TDL(Tapped Delay Line). To obtain actual performance, IS-95B system using PN codes(M-sequence) concatenated with Walsh codes is considered. The BER performance of voice/data service satisfying QoS requirement and the maximum capacity of voice users is derived in terms of various system parameters(voice activity factor, required SNR of voice/data users, the number of multi-codes, the number of voice/data users.,etc.). As a result, under the condition that the maximum allowable number of voice user is 38 in voice only system, as the number of multi-code is decreased by 1, the maximum allowable number of voice user is increased by 5% for system with 1 data user and 22.3% for system with 4 data users. Therefore, it is possible to increase maximum allowable number of users in IS-95B CDMA system by appropriate control of the number of multi-codes and required SNR according to channel environment and traffic characteristic.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2003.05a
• /
• pp.678-681
• /
• 2003

In this paper, we aims to develop a microcontroll er-based portable pulse oximeter using Compact Flash Interface. First, portable pulse oxineter system is designed to record 2 channel of biosignals simultaneously, including 1 channel of SpO$_2$ and 1 channel of pulse rate. It is very small and portable. Besides, the system makes it possible to measure a patients condition without an additional medical equipment. We tried to solve the problems generated by a patient's motion. That is, we added an analog circuit to a traditional pulse oximeter in order to eliminate the change of the base line. And we used 2D sector algorithm. As present, SpO$_2$ modules are completed. But there are still many further development needed in order to enhance the function. Especially, compact flash interface remains the most to complete. Second, ECG monitoring system uses almost same as present 3-lead ECG system. But we focus on the analog part, especially in filter. The proposed filter is composed of two parts. One is a filter to remove the power-line interface. The other is a filter to remove the baseline drift. A filter to remove the power-line and the baseline drift is necessarily used in the ECG system. The implemented filter have three features; minimizing the distortion in DC component, removing the harmonic component of power-line frequency. Using compact flash interface, we can easily transfer a patient's personal information and the measured signal data to a network based server environment. That means, it is possible to implement a patient's monitoring system with low cost.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.28 no.2
• /
• pp.131-136
• /
• 2008

Using ultrasonic standing waves, micro particles submerged or flowing in fluid can be manipulated. Due to acoustic radiation force of ultrasound, particles are forced to move to pressure nodal or antinodal lines. In this work, we propose a method to control the position of micro particle in a flow by adjusting the frequency of the standing wave. To this end, standing wave field generation system including a few millimeter thick micro channel was established using an immersible ultrasonic transducer. The present generation system works valid in a frequency range between 2.0 MHz and 2.5 MHz. We observed the SiC particles in water moved to pressure nodal lines by the standing wave. The effect of the channel thickness and operating frequency was also investigated. Interestingly, it was shown that the operating frequency have a close relation with the location of the pressure nodal line. Consequently, it fan be said that the position of particle movement rail be controlled by adjusting the ultrasound frequency. The maximum range of the controllable position was about 261 micrometers under the given condition. The resulted observations reveal the possibility of various applications of the ultrasonic standing wave to the manipulation of particles submerged in a fluid.

• Ecology and Resilient Infrastructure
• /
• v.4 no.4
• /
• pp.207-215
• /
• 2017

Hydraulic issues such as flow resistance, side wall correction, sediment, erosion and deposition, and channel design have close relation with distribution of bed shear stresses but the measurement of the distribution of bed shear stresses is not easy. In this study the Preston tube which makes possible relatively simple measurement of bed shear stresses is used to analyze the characteristics of bed shear distribution in compound open channels with different depth ratio. The Preston tubes are made and calibrated to develop the calibration formula and then they are applied to measure bed shear stress distribution in 5 cases depth ratio condition of compound channels. The results are compared with former experiment data, and characteristics of bed shear stress distributions are studied with different channel scales and Reynolds numbers. Although bed shear distributions with depth ratio show overall agreement with former studies, some differences are verified in bed shear variation, formation of inflection point in main channel, and distribution near floodplain junction which are due to high Reynolds number. Through the study applicability of the Preston tubes are also verified and characteristics of bed shear distribution in compound channels are suggested with Reynolds number and depth ratio.

• Korean Journal of Veterinary Research
• /
• v.35 no.2
• /
• pp.245-254
• /
• 1995

The density of ATP-sensitive potassium($K_{APT}$) channels, that open as intracellular ATP concentration falls below a critical level, is very high in skeletal muscle surface membrane and those high density may imply that $K_{ATP}$ channels have very important physiological roles. To elucidate a role of $K_{ATP}$ in relation to fatigue, the modulating effects of potassium channel openers and blockers on the fatigue velocity(FV) of mouse extensor hallucis longus muscle(EHL) were investigated in vitro. Twitch contraction was induced by an electrical field stimulation (EFS: 24-48V, 20ms, 0.2-4Hz) and resulting contraction force was isometrically recorded. The twitch forces were gradually decreased to 25% of initial contraction force(ICF) in $37.52{\pm}1.55sec$($mean{\pm}s.e.m.$, n=135), indicating the fatigue phenomena. The mean velocity for development of the fatigue was measured during the period that twitch force decreased to half($FV_{0/0.5}$) and during the period from half to 25%($FV_{0.5/0.25}$) of ICF. The fatigue was induced once every one hour and the tissue response was stable for up to 4 hours. In control condition, ICF was $5.8{\pm}0.12g$ (n=144) and decreased to 50% of ICF with the mean fatigue velocity of $0.182{\pm}0.006g/sec$($FV_{0/0.5}$, n=135) and from 50% to 25% of ICF with $0.084{\pm}0.004g/sec$($FV_{0.5/0.25}$, n=135). Cromakalim($50{\mu}M$) significantly increased $FV_{0.5/0.25}$(n=4). Glibenclamide($IC_{50}>50{\mu}M$), $Ba^{2+}$($IC_{50}=10{\mu}M$), 4-aminopyridine($FV_{0/0.5}$, $IC_{50}=0.5mM$; $FV_{0.5/0.25}$, $IC_{50}=2mM$) decreased both $FV_{0/0.5}$ and $FV_{0.5/0.25}$ concentration-dependently up to 75%. $TEA^+$(30mM), E-4031($10{\mu}M$), tolbutamide(1mM) decreased $FV_{0.5/0.25}$, but apamin(300nM) and $TEA^+$(10mM) showed no significant effects. Our results suggest that activation of the $K_{ATP}$ channels may be major cause of $K^+$ outflux during development of the fatigue and the isolated EHL muscle could be an useful experimental preparation in studying the fatigue phenomena in skeletal muscle. In addition, the possibility of activation of delayed rectifier during the fatigue development remains to be studied further.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2014.02a
• /
• pp.344-344
• /
• 2014

Transparent amorphous oxide semiconductors such as a In-Ga-Zn-O (a-IGZO) have advantages for large area electronic devices; e.g., uniform deposition at a large area, optical transparency, a smooth surface, and large electron mobility >10 cm2/Vs, which is more than an order of magnitude larger than that of hydrogen amorphous silicon (a-Si;H).1) Thin film transistors (TFTs) that employ amorphous oxide semiconductors such as ZnO, In-Ga-Zn-O, or Hf-In-Zn-O (HIZO) are currently subject of intensive study owing to their high potential for application in flat panel displays. The device fabrication process involves a series of thin film deposition and photolithographic patterning steps. In order to minimize contamination, the substrates usually undergo a cleaning procedure using deionized water, before and after the growth of thin films by sputtering methods. The devices structure were fabricated top-contact gate TFTs using the a-IGZO films on the plastic substrates. The channel width and length were 80 and 20 um, respectively. The source and drain electrode regions were defined by photolithography and wet etching process. The electrodes consisting of Ti(15 nm)/Al(120 nm)/Ti(15nm) trilayers were deposited by direct current sputtering. The 30 nm thickness active IGZO layer deposited by rf magnetron sputtering at room temperature. The deposition condition is as follows: a rf power 200 W, a pressure of 5 mtorr, 10% of oxygen [O2/(O2+Ar)=0.1], and room temperature. A 9-nm-thick Al2O3 layer was formed as a first, third gate insulator by ALD deposition. A 290-nm-thick SS6908 organic dielectrics formed as second gate insulator by spin-coating. The schematic structure of the IGZO TFT is top gate contact geometry device structure for typical TFTs fabricated in this study. Drain current (IDS) versus drain-source voltage (VDS) output characteristics curve of a IGZO TFTs fabricated using the 3-layer gate insulator on a plastic substrate and log(IDS)-gate voltage (VG) characteristics for typical IGZO TFTs. The TFTs device has a channel width (W) of $80{\mu}m$ and a channel length (L) of $20{\mu}m$. The IDS-VDS curves showed well-defined transistor characteristics with saturation effects at VG>-10 V and VDS>-20 V for the inkjet printing IGZO device. The carrier charge mobility was determined to be 15.18 cm^2 V-1s-1 with FET threshold voltage of -3 V and on/off current ratio 10^9.

• The Korean Journal of Physiology and Pharmacology
• /
• v.1 no.4
• /
• pp.435-443
• /
• 1997

We employed the whole-cell patch clamp technique to investigate the effects of arachidonic acid (AA) on barium inward current through the L-type calcium channels ($I_{Ba}$) and on osmotic stretch-induced increase of $I_{Ba}$ in guinea-pig antral gastric myocytes. Under isosmotic condition, AA inhibited $I_{Ba}$ in a dose-dependent manner to $91.1{\pm}1.4,\;72.0{\pm}3.2,\;46.0{\pm}1.8,\;and\;20.3{\pm}2.3%$ at 1, 5, 10, 30 mM, respectively. The inhibitory effect of AA was not affected by 10 ${\mu}M$ indomethacin, a cyclooxygenase inhibitor. Other unsaturated fatty acids, linoleic acid (LA) and oleic acid (OA) were also found to suppress $I_{Ba}$ but stearic acid (SA), a saturated fatty acid, had no inhibitory effect on $I_{Ba}$. The potency sequence of these inhibitory effects was AA ($79.7{\pm}2.3%$) ＞ LA ($43.1{\pm}2.7%$) ＞ OA ($14.2{\pm}1.1%$) at 30 ${\mu}M$. On superfusing the myocyte with hyposmotic solution (214 mOsm) the amplitude of $I_{Ba}$ at 0 mV increased ($38.0{\pm}5.5%$); this increase was completely blocked by pretreatment with 30 mM AA, but not significantly inhibited by lower concentrations of AA (1, 5 and 10 ${\mu}M$) (P＞0.05). Unsaturated fatty acids shifted the steady-state inactivation curves of $I_{Ba}$ to the left; the extent of shift caused by AA was greater than that caused by LA. The activation curve was not affected by AA or LA. The results suggest that AA and other unsaturated fatty acids directly modulate L-type calcium channels and AA might modulate the hyposmotic stretch- induced increase of L-type calcium channel current in guinea-pig gastric smooth muscle.

• The Korean Journal of Physiology and Pharmacology
• /
• v.20 no.1
• /
• pp.25-33
• /
• 2016

Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular $Ca^{2+}$ ($[Ca^{2+}]_i$)-dependent signaling affects the fate of cancer cells. Here we investigate the role of $Ca^{2+}$-activated $K^+$ channel (SK4) in head and neck squamous cell carcinoma cells (HNSCCs) of dif-ferent cell lines; SNU-1076, OSC-19 and HN5. Treatment with $1{\mu}M$ ionomycin induced cell death in all the three cell lines. Whole-cell patch clamp study suggested common expressions of $Ca^{2+}$-activated $Cl^-$ channels (Ano-1) and $Ca^{2+}$-activated nonselective cation channels (CAN). 1-EBIO, an activator of SK4, induced outward $K^+$ current (ISK4) in SNU-1076 and OSC-19. In HN5, ISK4 was not observed or negligible. The 1-EBIO-induced current was abolished by TRAM-34, a selective SK4 blocker. Interestingly, the ionomycin-induced cell death was effectively prevented by 1-EBIO in SNU-1076 and OSC-19, and the rescue effect was annihilated by combined TRAM-34. Con-sistent with the lower level of ISK4, the rescue by 1-EBIO was least effective in HN5. The results newly demonstrate the role of SK4 in the fate of HNSCCs under the $Ca^{2+}$ overloaded condition. Pharmacological modulation of SK4 might provide an intriguing novel tool for the anti-cancer strategy in HNSCC.

• Korean Journal of Environment and Ecology
• /
• v.22 no.1
• /
• pp.43-58
• /
• 2008

For this study, which was conducted in the summer from $2004\sim2007$, 10 small and medium sized streams in Korea were selected(Munsan and Gokreung Stream in the Han River watershed, Mi, Ssanggye and Nam Stream in the Nakdong River watershed, Gapeong and Jojong Stream in the Bukhan River watershed, Cheongmi, Yanghwa and Bokha Stream in the Namhan River watershed), and plant surveys were performed using the belt transect method on the most natural 1km sections of each stream in order to clarify the natural environment condition of the plants in each stream. In the results of the plant survey, the total number of plant species recorded was 296. After selecting 121 species of those surveyed plant in order of frequency, an RDA(Redundancy Analysis) and a Pearson Correlation Analysis were performed to determine the correlation between the selected plant species and environmental factors( such as distance from channel, size of bed material, number of bars, altitude, bed slope, width of channel, and measured data of water quality) of the study sites. There was no significant correlation between the 121 plant species and altitude, bed slope, and number of bars at the research sites, but the correlation of plant species with size of bed material, width of channel, electrical conductivity, and phosphate$(PO_4-P)$ concentration was from very high to moderate. Also, the spectrum of these plant species reflects the actual environmental conditions so the method used in the study seems to be correct, but owing to the range of diversity, the results of the study seem to be difficult to extend to other streams. Nevertheless, it is expected that this data can be used as a basic material for researching plants by stream characteristics or in selecting plant species for streams.