• Proceedings of the Ginseng society Conference
• /
• 2002.10a
• /
• pp.66-83
• /
• 2002

Recently, we have provided evidence that ginsenosides, the active components of Panax ginseng, utilize pertussis toxin (PTX)-insensitive $G{\alpha}_{q/11}-phospholipase\;C-{\beta}3(PLC-{\beta}3)$ signal transduction pathway for the enhancement of $Ca^{2+}-activated\;Cl^{-}$ current in the Xenopus oocyte (British J. Pharmacol. 132, 641-647, 2001; JBC 276, 48797-48802, 2001). Other investigators have shown that stimulation of receptors linked to $G{\alpha}-PLC$ pathway inhibits the activity of G proteincoupled inwardly rectifying $K^+$ (GIRK) channel. In the present study, we sought to determine whether ginsenosides influenced the activity of GIRK 1 and GIRK 4 (GIRK 1/4) channels expressed in the Xenopus oocyte, and if so, the underlying signal transduction mechanism. In oocyte injected with GIRK 1/4 channel cRNAs, bath-applied ginsenosides inhibited high potassium (HK) solution-elicited GIRK current $(EC_{50}:4.9{\pm}4.3\;{\mu}g/ml).$ Pretreatment of the oocyte with PTX reduced the HK solution-elicited GIRK current by $49\%,$ but it did not alter the inhibitory ginsenoside effect on GIRK current. Prior intraoocyte injection of cRNA(s) coding $G{\alpha}_q,\;G{\alpha}_{11}\;or\;G{\alpha}_q/G{\alpha}_{11},\;but\;not\;G{\alpha}_{i2}\;or\;G{\alpha}_{oA}$ attenuated the inhibitory ginsenoside effect. Injection of cRNAs coding $G{\beta}_{1{\gamma}2}$ also attenuated the ginsenoside effect. Similarly, injection of the cRNAs coding regulators of G protein signaling 1, 2 and 4 (RGS1, RGS2 and RGS4), which interact with $G{\alpha}_i\;and/or\;G{\alpha}_{q/11}$ and stimulates the hydrolysis of GTP to GDP in active GTP-bound $G{\alpha}$ subunit, resulted in a significant reduction of ginsenoside effect on GIRK current. Preincubation of GIRK channel-expressing oocyte in PLC inhibitor (U73122) or protein kinase C (PKC) inhibitor (staurosporine or chelerythrine) blocked the inhibitory ginsenoside effect on GIRK current. On the other hand, intraoocyte injection of BAPTA, a free $Ca^{2+}$ chelator, had no significant effect on the ginsenoside action. Taken together, these results suggest that ginsenosides inhibit the activity of GIRK 1/4 channel expressed in the Xenopus oocyte through a PTX-insensitive and $G{\alpha}_{q/11}$-,PLC-and PKC-mediated signal transduction pathway.

• Journal of KIISE:Information Networking
• /
• v.35 no.3
• /
• pp.227-234
• /
• 2008

The development of wireless network technology allows high data rate seamless communication irrespective of the place and time in various emerging mobile service environment. Unlike wired networks, however, wireless networks utilize expensive limited bandwidth. MBS(Multicast Broadcast Service), which is supported by mobile WiMAX system based on IEEE802.16e, overcomes this problem using a shared downlink channel for efficiently supporting a number of users. However. the coverage and throughput of the system are significantly affected by the channel condition. In this paper we propose on MBS system employing Mobile Multi-Hop Relay(MMR) and adaptive modulation and coding(AMC) scheme. The result of NS-2 computer simulation shows that the throughput and transmission time are substantially improved by the proposed approach compared to the existing MBS system.

• The Journal of the Korea Contents Association
• /
• v.12 no.4
• /
• pp.31-39
• /
• 2012

DVC(Distributed Video Coding) techniques have been attracting a lot of research works since these enable us to implement the light-weight video encoder and to provide good coding efficiency by introducing the feedback channel. However, the feedback channel causes the decoder to increase the decoding complexity and requires very high decoding latency because of numerous iterative decoding processes. So, in order to reduce the decoding delay and then to implement in a real-time environment, this paper proposes several parity bit estimation methods which are based on the temporal correlation, spatial correlation and spatio-temporal correlations between LDPCA frames on each bit plane in the consecutive video frames in pixel-domain Wyner-Ziv video coding scheme and then the performances of these methods are compared in fast DVC scheme. Through computer simulations, it is shown that the adaptive spatio-temporal correlation-based estimation method and the temporal correlation-based estimation method outperform others for the video frames with the highly active contents and the low active contents, respectively. By using these results, the proposed estimation schemes will be able to be effectively used in a variety of different applications.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.31 no.4B
• /
• pp.270-277
• /
• 2006

In the wireless adaptive modulation and coding(AMC) systems, the modulation type of user's connection can be changed dynamically. and the ongoing connection might fail due to the change of modulation. In this paper, we approach the AMC-induced CAC problem by focusing on the guaranteed connection. Three kinds of calls, new, handoff, and modulation-changed calls, are considered. We propose a modified guard channel CAC scheme that allows the modulation-changed and handoff calls to use the guard channel. Then we analyze a Markov model for the CAC scheme with long-term AMC in mind. According to the simulation results, the proposed approach reduces the call dropping probability for modulation-changed calls, which suggests the threshold of guard channels can be determined based on the proposed approach.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.9 no.4
• /
• pp.43-51
• /
• 2010

In this paper, we studied line coding technology tendency for high speed data communication at LED-ID (Identification) communication system in indoor environment. A LED-ID technology is a communication using visible ray (RGB) that come out in LED device. It is energy curtailment effect and possible in ubiquitous network service applications. The LED-ID system has the above advantages about that the communication throughout the whole room is enabled by high power lighting and lighting equipment with white colored LED which are easy to install and have good outward appearance. Therefore, the transmission by light waves is more suitable for wireless networks than by radio waves. We compared with the NRZ, AMI, 4B5B, HDB3, 8B10B line coding for efficient in error detection and serves data transmission of high speed.

• Journal of Communications and Networks
• /
• v.7 no.2
• /
• pp.157-170
• /
• 2005

The combination of multiple antennas and multi-carrier code division multiple-access (MC-CDMA) is a strong candidate for the downlink of the next generation mobile communications. The study of such systems in scenarios that model real-life trans-missions is an additional step towards an optimized achievement. We consider a realistic MIMO channel with two or four transmit antennas and up to two receive antennas, and channel state information (CSI) mismatches. Depending on the mobile terminal (MT) class, its number of antennas or complexity allowed, different data-rates are proposed with turbo-coding and asymptotic spectral efficiencies from 1 to 4.5 bit/s/Hz, using three algorithms developed within the European IST-MATRICE project. These algorithms can be classified according to the degree of CSI at base-station (BS): i) Transmit space-frequency prefiltering based on constrained zero-forcing algorithm with complete CSI at BS; ii) transmit beamforming based on spatial correlation matrix estimation from partial CSI at BS; iii) orthogonal space-time block coding based on Alamouti scheme without CSI at BS. All presented schemes require a reasonable complexity at MT, and are compatible with a single-antenna receiver. A choice between these algorithms is proposed in order to significantly improve the performance of MC-CDMA and to cover the different environments considered for the next generation cellular systems. For beyond-3G, we propose prefiltering for indoor and pedestrian microcell environments, beamforming for suburban macrocells including high-speed train, and space-time coding for urban conditions with moderate to high speeds.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.22 no.9
• /
• pp.2014-2026
• /
• 1997

In this paper, the performances of wireless asynchronous transfer mode (ATM) cell transmission in mobile work are analyzed. We adopt 16Star QAM as amodulation technique in wireless channel and considered Reed-Solomon, convolutional, and concatenated coding to improve the error rate performances, and also proposed the Partial Concatenated Coding (PCC) technique as UEP(unequal error protection) code for efficient transmission of ATM cell in the air interface. We consider Doppler's effect, Rician fading, and diversity technique of maximal-ratio combining (MRC) for mobile channel model. For performance measure, we analyze bit error rate, ATM cell loss probability, ATM cell error probability, and network performances of ATM cell transmission delay and throughput. The numerical results show that the adoption of PCC is a prospective way for the evolution of future wireless ATM network on mobile environment.

• Journal of Convergence Society for SMB
• /
• v.6 no.3
• /
• pp.49-55
• /
• 2016

This paper proposes an adaptive video signal transmission scheme in order to ensure the QoS (Quality of Service) of user requirements. SVC (Scalable Video Coding) is an effective transmission scheme, because that can transmit video signal according to the video layer's weight. However, in previous works, those adaptive transmission systems which are considered about the various channel environments and user requirements have not been insufficiently studied. So, we propose the SVC signal transmission using inter-layer differential OVSF code allocation scheme in MC-CDMA. The proposed scheme is able to obtain each layer signal's protection order and control the sub-block of MC-CDMA by feedback information from receiver. Therefore, our proposed scheme is possible to provide the video quality for each users according to variable channel environments. The simulation results demonstrate the enhancement of proposed system in terms of BER performance.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.33 no.1A
• /
• pp.50-58
• /
• 2008

The use of space-division multiple access(SDMA) in the downlink of multiuser multi-input/multi-output(MIMO) wireless transmission systems can provide substantial gains in system throughput. When the channel state information(CSI) is available at the transmitter, a considerable performance improvement can be attained by adapting the transmission rates to the reported CSI. In addition, to combat frequency selective fadings in wideband wireless channels, bit-interleaved coded OFDM(BIC-OFDM) modulation schemes are employed to provide reliable packet delivery by utilizing frequency diversity through channel coding. In this paper, we propose an adaptive modulation and coding(AMC) scheme combined with an opportunistic scheduling technique for the MIMO BIC-OFDM with bandwidth-limited feedback channels. The proposed scheme enhances the link performance by exploiting both the frequency diversity and the multiuser diversity. To reduce the feedback information, the proposed AMC scheme employs rate adaptation methods based on an OFDM symbol rather than on the whole subchannels. Simulation results show that the proposed scheme exhibits a substantial performance gain with a reasonable complexity over single antenna systems.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.10 no.7
• /
• pp.1118-1130
• /
• 1999

In this paper, error performance of DS/FH CDMA system has been analyzed in a radio channel which is characterized by near-far problem and multi-path fading. The DS/FH CDMA system adopts Maximum Ratio Combining(MRC) diversity and BCH(Bose-Chau dhuri-Hocquenghem) coding techniques to enhance system performance. Using the derived error probability equation, the error performance of DS/FH CDMA system has been evaluated and shown in figures to discuss as a function of PN code length(N), hopping rate(q), number of diversity branch(M), coding rate($\gamma$) and bit energy per noise power ratio ${E_b/N_o}$. The results show that DS/FH system is more effective to restrain the affection of near-far problem and multi-path fading than DS system. And there is a substantial enhancement in performance by employing an MRC diversity or BCH coding techniques. Consequently, we expected that proposed system structure is reliable to the voice communication system in near-far problem and multi-path fading channel.