• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2009년도 춘계학술대회 논문집
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• pp.985-986
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• 2009

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2008년도 춘계학술대회 논문집
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• pp.773-774
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• 2008

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2008년도 춘계학술대회 논문집
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• pp.481-482
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• 2008

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2011년도 춘계학술대회 논문집
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• pp.949-950
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• 2011

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2011년도 춘계학술대회 논문집
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• pp.1199-1200
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• 2011

• The Korean Journal of Physiology and Pharmacology
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• 제26권4호
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• pp.263-275
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• 2022

There is a paucity of detailed data related to the effect of senescence on the mitochondrial antioxidant capacity and redox state of senescent human cells. Activities of TCA cycle enzymes, respiratory chain complexes, hydrogen peroxide (H₂O₂), superoxide anions (SA), lipid peroxides (LPO), protein carbonyl content (PCC), thioredoxin reductase 2 (TrxR2), superoxide dismutase 2 (SOD2), glutathione peroxidase 1 (GPx1), glutathione reductase (GR), reduced glutathione (GSH), and oxidized glutathione (GSSG), along with levels of nicotinamide cofactors and ATP content were measured in young and senescent human foreskin fibroblasts. Primary and senescent cultures were biochemically identified by monitoring the augmented cellular activities of key glycolytic enzymes including phosphofructokinase, lactate dehydrogenase, and glycogen phosphorylase, and accumulation of H₂O₂, SA, LPO, PCC, and GSSG. Citrate synthase, aconitase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase, and complex I-III, II-III, and IV activities were significantly diminished in P25 and P35 cells compared to P5 cells. This was accompanied by significant accumulation of mitochondrial H₂O₂, SA, LPO, and PCC, along with increased transcriptional and enzymatic activities of TrxR2, SOD2, GPx1, and GR. Notably, the GSH/GSSG ratio was significantly reduced whereas NAD⁺/NADH and NADP⁺/NADPH ratios were significantly elevated. Metabolic exhaustion was also evident in senescent cells underscored by the severely diminished ATP/ADP ratio. Profound oxidative stress may contribute, at least in part, to senescence pointing at a potential protective role of antioxidants in aging-associated disease.

• International Journal of Quality Innovation
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• 제8권3호
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• pp.71-80
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• 2007

Apart from the customer demands themselves, the weightings of the customer demands are one of the main input data of a QFD (Quality Function Deployment) and furthermore of the actual construction process of products. Up to now, most interviews with stakeholders have been carried out with questionnaires and then absolute weightings have been used. Now it has been analysed if the use of other interview and evaluation techniques, e.g. relative weightings and Analytic Hierarchy Process (AHP), can improve the precision of the demands and wishes of the stakeholders. Now the task was to analyse if the use of relative weightings as input of a QFD is possible at all, how they have to be adapted and if an increase in precision compared to the use of absolute weightings is reached. When using AHP during the product development it has become clear that only up to seven demands can be rated at the same time by customers. That means that a kind of hierarchy has to be developed to correctly transfer the demands and their weightings into the QFD.

• 디지털융복합연구
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• 제12권9호
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• pp.209-217
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• 2014

현대인의 피로누적과 스트레스로 인한 근육 뭉침이나 어깨 결림과 같은 고통을 호소하는 사람들을 위해 힐이, 피로회복 개념으로 안마에 대한 욕구가 계속 증가하고 있다. 이를 위해 안마의자가 개발되고 있으나 한국인의 체형에 맞지 않아 가장 효율적인 안마를 제공하지 못하고 있다. 본 논문에서는 관련연구로 안마, 어셈블러, 안마강도, 한국인의 체형을 분석하고 효율성을 극대화하기 위한 기능을 분석하였다. 또한 한국인 체형에 맞는 동작제어기 및 알고리즘을 개발하였다.

• 한국실내디자인학회논문집
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• 제17호
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• pp.136-142
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• 1998

In early 20th Century Neo Art Movement and Fuctionalim in Europe effected to create new tendency as Modern Design and technical development through Industrial Revolution offered technical background to realize Modern Design. All these things were basic to establish 1920s and the concept as Modern Design had been established at this time in field of Architecture and design. Thubular-steel Chair which used industrial material based on social andtechnical circumstance came out as an epochal event and which symbolize Modern Design have enlarged their concept with 1920s European Dwelling Space. According to each tendency arrange characteristics as classifying on the society-cultural spatial plastic technical sides multiple dwelling house and tubular-steel chair for low income brackets have characteristic of (1) the pursuit of social functionalism design for public(socity-cultural characteristics) (2) the pursuit of simplicity based on functionalism (plastic charcteristics) (3) the standardization for mass production (technical characteristc). In conclusion the characteristics of tubular-steel chair which correspond with dwelling space in 1920's is presented a type for relation between furniture and space which correspond with formating in the formative period of Modern-design.

• 동력기계공학회지
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• 제16권1호
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• pp.24-29
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• 2012

Recently, in the movie theater, the special chair is installed to maximize the viewing effect of movies. It is structured to convey a vibrational stimulus to a specially-designated parts of human body by attaching a vibration transducer to a existing theater chair. This paper describes the analysis of the vibration transfer characteristic of a foaming sponge seat for the design of the special chair. We could not apply the structural analysis S/W because it is difficult to obtain the mechanical properties and damping coefficients of the various type sponges. And then we computed the transfer functions by the global curve fitting program based on experimental modal analysis. The experimental response results comparatively coincide with those by the global curve fitting program. We also could obtain the natural frequencies, the modal damping coefficient ratio, the modal vectors and the whole transfer functions. Therefore we could analyze the dynamic characteristic for design of foaming sponge seat.