• The Korean Journal of Pain
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• v.37 no.2
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• pp.107-118
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• 2024

Nociplastic pain by the "International Association for the Study of Pain" is defined as pain that arises from altered nociception despite no clear evidence of nociceptive or neuropathic pain. Augmented central nervous system pain and sensory processing with altered pain modulation are suggested to be the mechanism of nociplastic pain. Clinical criteria for possible nociplastic pain affecting somatic structures include chronic regional pain and evoked pain hypersensitivity including allodynia with after-sensation. In addition to possible nociplastic pain, clinical criteria for probable nociplastic pain are pain hypersensitivity in the region of pain to non-noxious stimuli and presence of comorbidity such as generalized symptoms with sleep disturbance, fatigue, or cognitive problems with hypersensitivity of special senses. Criteria for definitive nociplastic pain is not determined yet. Eight specific disorders related to central sensitization are suggested to be restless leg syndrome, chronic fatigue syndrome, fibromyalgia, temporomandibular disorder, migraine or tension headache, irritable bowel syndrome, multiple chemical sensitivities, and whiplash injury; non-specific emotional disorders related to central sensitization include anxiety or panic attack and depression. These central sensitization pain syndromes are overlapped to previous functional pain syndromes which are unlike organic pain syndromes and have emotional components. Therefore, nociplastic pain can be understood as chronic altered nociception related to central sensitization including both sensory components with nociceptive and/or neuropathic pain and emotional components. Nociplastic pain may be developed to explain unexplained chronic pain beyond tissue damage or pathology regardless of its origin from nociceptive, neuropathic, emotional, or mixed pain components.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.324-324
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• 2017

Total 15 different corn hybrids, Kwangpyeongok, Gangdaok, Yanganok, Singwangok, Jangdaok, Cheonganok, Cheongdaok, Andaok, Dapyeongok, Pyeongkangok, Pyeonganok, Daanok, Sunwon P3394, Gangilok, P3394, had been used to investigate the plant growth and yield of corn hybrids depends on the sowing date. Sowing dates were April 5th, June 25th, and July 5th and all experiments had three repeats. The growth of Gangdaok was the best. However, in the case of Kwangpyeongok, the growth was not the best to compare with Gangdaok, but the stem to ear height ratio was lower than Gangdaok, it may be better for the stable cultivation. Both of the growth and yield of Daanok was not good regardless of planting date, but the yield and ear shape of Pyeongkangok and Dapyeongok were good for fresh corn. The growth and yield of 15 different corn hybrids were variable depends on the planting date, however, the growth degree days (GDD) was the most important factor for the maturity of the corn. More than $1500^{\circ}C$ of GDD was enough to harvest mature corn hybrids in the central region of Korea. Besides the yield and growth, other characters such as sweetness and taste as a food should be investigated further for the fresh corn to be suggested.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1133-1133
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• 2001

Fruit sweetness, as indexed by total soluble solids (TSS), and fruit acidity are key factors in the description of the fruit eating quality. Our group has been using short wave NIR spectroscopy (SW-NIR; 700-1100 nm) in combination with chemometric methods (PLS and MLR) for the non-invasive determination of the fruit eating quality (1,2). In order to further improve calibration performance, we have investigated SW-NIR spectra of sucrose and D-glucose. In previous reports on the band assignment for these sugars in the 1100-2500 nm spectral region (3-7), it has been established that change in concentration, temperature and physical state of sugars reflects on the shape and position of the spectral bands in the whole NIR region(5-7). The effect of change in concentration and temperature of individual sugar solutions and sugar spiked Juice samples was analysed using combined spectroscopic (derivative, difference, 2D spectroscopy) and linear regression chemometric (PLS, MLR) techniques. The results have been compared with the spectral data of a range of fruit types, varying in TSS content and temperature. In the 800-950 nm spectral region, the B-coefficients for apples, peaches and nectarines resemble those generated in a calibration of pure sucrose in water (Fig. 1). As expected, these fruits exhibit better calibration and prediction results than those in which the B-coefficients were poorly related to those for sugar.(Figure omitted).

• Journal of Ocean Engineering and Technology
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• v.21 no.6
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• pp.72-80
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• 2007

The tsunami that resulted from the Central East sea Earthquake, which registered 7.7 on the Richter scale, that occurred over the entire water region in Akita on May. 26, 1983 and the tsunami that was triggered by the Southwest off Hokkaido Earthquake (7.8 on the Richter scale) that occurred in Southwest off Hokkaido on July 12, 1993 are representative cases that led to considerable damage in life and property, not only in Japan but also in Korea. In this study, multi-grid method was used in order to reproduce sufficiently the shoaling effect that occurs as water depth becomes shallow in the shallow water region and moving boundary condition was introduced to consider the runup in the coastal region. For the tsunamis that exerted considerable effect on the East Sea coast of Korea that were caused by the Central East Sea Earthquake in 1983 and the Southwest off Hokkaido Earthquake in 1993, characteristics like water level rise and propagation in the East Sea coast will be examined using numerical simulations. At the same time, these values will be compared with observed values. In addition, maximum water level rise and change in the water level with respect to time that were caused by the tsunamis were examined at each location along the East sea coast. Usefulness of numerical analysis was verified by comparing with observed values.

• Journal of the Korean earth science society
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• v.22 no.4
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• pp.292-300
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• 2001

By using two methods we obtained plane solutions for 5 groups of earthquakes including 13 events, which occurred in the central region of South Korea after December 1997. The first method is the composite fault plane solution by P wave polarity, and the second the solution by amplitude ratio (SV/P, SH/P, SV/SH) and P and S wave polarities. The two method results show similar results. The strike of fault is in the direction of NNE-SSW and WNW-ESE with the movement of strike-slip or strike-slip including thrust component. The compressional axis of the stress field dominantly trends ENE-WSW or NE-SW. The results are almost consistent with the other main events occurred in and around the Korean Peninsula.

• Journal of The Korean Society of Grassland and Forage Science
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• v.43 no.4
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• pp.199-205
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• 2023

Pasture formation and management are crucial to avoid yield reduction. This experiment aimed to examine the effects of tall fescue-centered mixed-seeding combinations on yield and vegetation changes in perennial pastures in the central region for two years, from September 2020 to October 2022. The treatments were arranged in three replications in a randomized block design: control (C), tall fescue-based mixture-1 (T-1), and tall fescue-based mixture-2 (T-2). The tall fescue (TF), orchard grass (OG), perennial ryegrass (PRG), Kentucky bluegrass (KBG), and white clover (WC) were used. The emergency rate of grasses (70.0 to 73.3%) did not differ among mixed seeding combinations. Overwintering rates (81.7 to 83.3%) were similar among treatments. The plant height of grasses was similar at each harvest date, with the highest height (86.2 cm) recorded in the second harvest of the first year, followed by that (58.4 cm) in the third harvest of the first year; it was least (38.9 cm) in the fourth harvest of the second year. There was no significant difference in the dry matter yield of grasses among the mixed seeding combination treatments in the first, third, or fourth harvests of the first year (p>0.05). For second-year grasses, dry matter yield was not significantly different in harvest date among the treatments (p>0.05). Based on mixed seeding ratio, orchard grass showed the highest yield at 70% in the C treatment, followed by tall fescue at 80% and 60% in the T-1 and T-2 treatments, respectively, in the first harvest after seeding. There was no significant difference in feed value between treatments (p>0.05), but a significant difference was observed between the third and fourth harvest (p<0.05). Therefore, it indicated that it is important to create perennial pastures in the central region through mixed seeding combinations centered on tall fescue.

• Journal of Food and Nutrition Research
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• v.9 no.7
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• pp.350-356
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• 2021

This study was conducted in Cheonan of central region in South Korea to identify alfalfa cultivars with superior adaptability to the local environment. To evaluate the growth characteristics, productivity, and feed value of 26 alfalfa cultivars, field experiments were conducted with a randomized block design (three replicates) for three years. Among the 26 alfalfa cultivars, "Natsuwakaba" showed the highest dry matter yield (DMY, 37,083 kg/ha), with a significantly higher three-year average than that of other cultivars. Furthermore, the three-year-average DMYs of "Alfalfa short" (31,044 kg/ha) and "Radar II Brand" (31,163 kg/ha) were significantly higher than those of other cultivars. In addition, differences among the feed values of the alfalfa cultivars were relatively less significant than the differences among their productivity, as the feed value was less influenced by the cultivation conditions and cultivars. Although "Jin Huang Hou" and "Certified organic" exhibited the highest feed values when cultivated in central region in South Korea, "Natsuwakaba" outperformed all cultivars in both productivity and feed value. The acid and neutral detergent fiber (ADF and NDF, respectively) contents of "Jin Huang Hou" (38.9% and 47.26%, respectively) were significantly lower than those of other cultivars. In contrast, the ADF and NDF contents of "Burgaltai" (46.52% and 55.56%, respectively) implied poor feed value upon cultivation in South Korea. The crude protein (CP) content in the alfalfa cultivars ranged from 14.95% to 19.44% during early flowering, and the highest CP content was observed for "Certified organic." The in-vitro digestibility of alfalfa was approximately 70% for all cultivars during early flowering, indicating good digestibility of most of the cultivars.

• Proceedings of the Microbiological Society of Korea Conference
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• 2001.11a
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• pp.97-101
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• 2001

The fusion between viral envelope and target cell membrane is a central step of viral infection, and the fusion proteins located at viral envelope mediate such process. Gp41 of HIV is one of the fusion proteins whose structure and mechanism of membrane fusion had been extensively studied. Functionally important motives of gp41 are the N-terminus fusion peptide, the coiled-coil and the membrane proximal C-peptide regions. The role of these regions during the fusion process had been thoroughly examined. Specially, insertion of the fusion peptide into membrane and conformational change of the coiled-coil and C-peptide regions are assumed to be critical for the fusion mechanism. In addition, the coiled-coil region has been shown to interact with membrane, and the C-peptide region regulates the interaction in a dose dependent manner. Furthermore, fusion defective mutations of the coiled-coil region dramatically changed its binding affinity to membrane. These results suggested that the membrane binding property of the coiled-coil region is important for the fusion activity of gp41, and such property could be modulated by the interaction with the C-peptide region.

• Journal of Korean Society for Quality Management
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• v.29 no.1
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• pp.24-40
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• 2001

Response surface designs can be classified, according to the shape of the experimental region, into spherical designs and cuboidal designs. Among the central composite design(CCD)s and the Box-Behnken design(BBD)s that are popular in practice, when the number of factors is k, spherical designs are tile CCDs with the axial value being $\sqrt{\textit{k}}$ and the BBDs, and cuboidal designs are the CCDs with the axial value being 1. With the CCDs having $\sqrt{\textit{k}}$ as the axial value, the radius of the experimental region varies with number of factors, but these designs are the 5-level designs. With the BBDs that are 3-level designs, the radius of the experimental region does not vary with the number of factors. In this article, we propose tile 3-level spherical designs which are constructed so that tile radius of the experimental region varies with the number of factors.

• Journal of the Korean Chemical Society
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• v.65 no.2
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• pp.121-124
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• 2021

RNA molecules which bind to the G-rich sequence in the 5'-UTR RNA which plays an important role in expression of N-ras, were selected. The secondary structures of five selected RNA aptamers including primer sequence were found by the CLC RNA workbench ver. 4.2 program (www.clcbio.com) and investigated with RNA structural probes such as RNase T1 which has specificity for a G in single-stranded region, RNase V1 specific for double strand and nuclease S1 specific for single strand. The generalized secondary structure model was proposed and characterized. It was composed of a central long double strand region flanked by single strand region at both end sides. The double strand region had an internal single-strand region and bulges. The single strand loop in the right side was composed of four or five nucleotides.