• 제목/요약/키워드: central extension

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Risk factor for pituitary dysfunction in children and adolescents with Rathke's cleft cysts

  • Lim, Han-Hyuk;Yang, Sei-Won
    • Clinical and Experimental Pediatrics
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    • 제53권7호
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    • pp.759-765
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    • 2010
  • Purpose: This study evaluated the clinical manifestations of and risk factors for pituitary insufficiency in children and adolescents with Rathke's cleft cysts. Methods: Forty-four patients with Rathke's cleft cysts younger than 19 years who visited Seoul National University Children's Hospital between January 1995 and September 2009 were enrolled. Rathke's cleft cysts were confirmed histologically through an operation in 15 patients and by brain magnetic resonance imaging (MRI) in 29 patients. The clinical, hormonal, and imaging features were reviewed retrospectively. Results: The clinical presentation of symptomatic patients was as follows: headache (65%), endocrinopathy (61%), and visual disturbance (19%). Endocrinopathy included central precocious puberty (18%), diabetes insipidus (14%), general weakness (11%), and decreased growth velocity (7%). After surgery, hyperprolactinemia resolved in all patients, but growth hormone insufficiency, hypothyroidism, and diabetes insipidus did not improve. Pituitary insufficiency except gonadotropin abnormality correlated significantly with severe headache, visual disturbance, general weakness, and cystic size. Suprasellar extension of cysts and high signals in the T2-weighted image on brain MRI were related to hypothyroidism, hypocortisolism, and diabetes insipidus. Multivariable linear regression analysis showed that only general weakness was a risk factor for pituitary insufficiency ($R^2$=0.549). Conclusion: General weakness is a risk factor for pituitary insufficiency in patients with Rathke's cleft cysts. When a patient with a Rathke's cleft cyst complains of general weakness, the clinician should evaluate pituitary function and consider surgical treatment.

사용 편의성에 기초한 주작업영역의 결정 (Determination of Primary Working Area based on Working Comfort)

  • 박성준;정의승
    • 대한인간공학회:학술대회논문집
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    • 대한인간공학회 1995년도 춘계학술대회논문집
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    • pp.155-164
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    • 1995
  • For efficient operation, vital hand controls must be easily controlled by the operator from his normal working position. The primary working area based on operator's working comfort was developed to serve as a design guideline tothe control panel layout. Ten male subjects participated in the experiment in which working comfort was measured for two controls of a lever type control and a knob type control with respect to the frontal and sagittal distances from the body center and the slope of a workplace. The response surface methodolgy using a central composite design was employed to develop a prediction model for perceived working comfort of each control. Both controls have a similar pattern of comfortable working area, but the lever type control has slightly broader working area. The concept of the proposed working area is a significant extension to the conventional working area such as Farley's or Squires' curves. It is shown that the distance toa control device and the slope have a quadratic effect to working comfort. It is noticeable that comfortable working area exists outside the conventional working area. The result of the response surface analysis also indicated that a little slope of about 15 .deg. for a control panel improves working comfort.

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Extraneural Metastasis of Glioblastoma Multiforme Presenting as an Unusual Neck Mass

  • Seo, Young-Jun;Cho, Won-Ho;Kang, Dong-Wan;Cha, Seung-Heon
    • Journal of Korean Neurosurgical Society
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    • 제51권3호
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    • pp.147-150
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    • 2012
  • Glioblastoma multiforme(GBM) is the most aggressive intracranial tumor and it commonly spreads by direct extension and infiltration into the adjacent brain tissue and along the white matter tract. The metastatic spread of GBM outside of the central nervous system (CNS) is rare. The possible mechanisms of extraneural metastasis of the GBM have been suggested. They include the lymphatic spread, the venous invasion and the direct invasion through dura and bone. We experienced a 46-year-old man who had extraneural metastasis of the G8M on his left neck. The patient was treated with surgery for 5 times, radiotherapy and chemotherapy. He had survived 6 years since first diagnosed. Although the exact mechanism of the extraneural metastasis is not well understood, this present case shows the possibility of extraneural metastasis of the G8M, especially in patients with long survival.

조명 설계 시스템을 위한 데이터베이스 개발에 관한 연구 (A Study on the Development of Database for Lighting Design System)

  • 조성오
    • 한국실내디자인학회논문집
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    • 제13권4호
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    • pp.196-203
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    • 2004
  • In The Lighting design is important to acknowledge appearance space. Development of artificial light makes a extension to life space in the Modern life. With the rapid development of efficient light sources, have lighting design acquired the tools that allow artificial lighting to be produced with adequate illuminance levels. However, by the task of defining the objectives and methods behind discipline, of deciding on the criteria by which the artificial lighting that is now provide many available data to be anpaied. The main concern is which illuminace levels and types of lighting will ensure optimum visual performance, high productive and safety at design which are affordable. This study is support to standard design process with material reflection rate, installing the lighting fixture, task illuminance level and automatic arithmetic calculation during the lighting design. Lighting Design database can check and support other final lighting level. A quantitative light that is primarily oriented toward providing a recommended illuminance level, the criterion of develop a concept that goes beyond the requirements that would ensure productivity and safety to meet the needs of the architecture and interior space. illuminance level is compose to space task and space code according to KS A 3011. To be able to design the visual effect of an environment the central reference quantity has to provided the Database.

Yield Gap Analysis of Mulberry Sericulture in Northwest India

  • Bhatia, Narendra Kumar;Yousuf, Mohammad;Nautiyal, Raman
    • International Journal of Industrial Entomology and Biomaterials
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    • 제27권1호
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    • pp.131-141
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    • 2013
  • At the interface of reducing agricultural income and increasing unemployment in agrarian economy of rural India, this article summarizes and evaluates the state of mulberry sericulture in northwest India, which includes Himachal Pradesh, Punjab, Rajasthan, Uttarakhand, and Uttar Pradesh. In $11^{th}$ plan period (2007-2012), there was an addition of 6 196 ha (217.09 %) of mulberry acreage at annual linier growth rate of 33.44%. However, total silk production could increase only by 54.64 MT (78.57%) at annual linier growth rate of 15.59 %, due to 43.93% (10.82 kg/ha) reduction in silk productivity at negative growth rate of -13.46%, annually. And now, average raw silk productivity in north-western states of India remains at 13.81 kg/ha, which is lower by 452.93 % (76.36 kg) in comparison to the national average of 100.90 kg/ha. Paper summaries the reasons for increasing cocoon yield gap at farmer's level and discuss the ways and means to increase raw silk productivity to improve the livelihood delivery of mulberry sericulture in northwest India.

사례연구 : 해외 프로젝트 파이낸스 투자 사례와 실물옵션기반 투자 의사결정 (Case Study : A Real Options Approach to an Overseas Project Finance Deal)

  • 변진호;최문섭
    • 대한산업공학회지
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    • 제39권5호
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    • pp.429-439
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    • 2013
  • The Korean Veterans' Pension Fund has previously pre-purchased Gibril Tower on Business Complex in Dubai, UAE, via a project-financed construction investment. Although the property is near completion, the investor syndicate's attempt to debt-finance due arrears was foiled in Dubai central bank's credit control of real estaterelated loans. Accordingly, the investment coordinator offered an additional capital injection, a collateralized leverage, and a maturity extension to the syndicate. If the syndicate rejects the offer, they may risk a nearcomplete capital loss and a possible default of the main contractor. Otherwise, the syndicate may still face uncertainties regarding interest receivables, principal re-payment, foreclosure, economic recession in Dubai, and the Islamic bond bill in the Korean Parliament. A possible exercise of the latter option may be due to the agency-prone nature of pension fund managers. Given these qualitative risk factors as at April 1, 2011, a real options approach-implied optimal decision suggests an extended and complete cash augmentation into the project finance deal.

필드버스 공압 솔레노이드 밸브/센서시스템 설계 및 성능평가 특성해석 (A Study on the Design and Performance Evaluation Technology of Fieldbus Pneumatic Solenoid Valve/Sensor System)

  • 김동수;홍춘표
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2001년도 추계학술대회논문집A
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    • pp.865-870
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    • 2001
  • For pneumatic system control, we need a data transmission system with high speed and high reliability or information interchange between main computer and solenoid valves and I/O devices. This paper presents a set of design techniques for a data communication system that is mainly used for pneumatic system control. For this purpose, we first designed hardware modules for an interface between central control module and local node that handles the operation of solenoid valves. In addition we developed a communication protocol for construction of RS-485 based multidrop network, and this protocol is basically designed with a kind of polling technique. Finally we evaluated performance of the developed system. The field test results show that, even under high noise environment, the data transmission of 375Kbps rate is possible up to 1,000m without using repeater. In addition, the system developed in this research is proved to be used easily for extension of a communication network because of its module structure.

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Occurrence of Eggplant Scab Caused by Cladosporium cucumerinum in Korea

  • Kwon, Jin-Hyeuk;Kang, Soo-Woong;Park, Chang-Seuk
    • The Plant Pathology Journal
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    • 제15권6호
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    • pp.345-347
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    • 1999
  • A scab disease on eggplant (Solanum melongena L. cv. Chukyang) in plastic film houses around Kimhae area in Korea during the winter season of 0998-1999. The disease started on leaves with small dark brown spots which were gradually expanded to 1 to 3 mm diameter lesions. Later, the central parts of the lesions became collapsed and detached to make holes. Dark brown mold was grown out of the lesions on the lower side of leaf. Numerous conidia were produced on the lower side of leaf. Numerous conidia were produced on the diseased leaves and appeared to be readily dispersed in the air. A fungus was isolated from the diseased leaves, and tested for Koch's postulates to prove the causal agent of the desease. The isolated fungus grew on potato dextrose agar, forming greenish black to pale brown colonies. Conidia were ellipsoidal, fusiform or subspherical, mostly one-celled but occasionally septated, and formed in long branched chains on the erected conidiophores which were pale olevaceous brown and variable in length between 12.4 and $393.4\mu\textrm{g}$. The fungus was identified as Cladosporium cucumerinum Ellis Arthur based on the above morphological characteristics examined. The optimum temperature for mycelial growth and conidial formation was about 20 to $25^{\circ}$. In addition to cucumber, the fungus was also pathogenic to watermelon, pumpkin and oriental melon. This is the first report on the scab disease of eggplant in Korea.

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Description of The Geology of The Sangdong Tungsten Deposit with Suggestions for Further Exploration Using Geochemical Techniques

  • Han, Tai Hwan
    • 자원환경지질
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    • 제11권4호
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    • pp.143-167
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    • 1978
  • The Sangdong tungsten (mostly scheelite) mine is located on the southern limb of a major syncline, the Hambaeg syncline, in a thick sequence of lower Paleozoic sedimentary rocks in the mideastern part of south Korea. Productive scheelite mineralization in Sangdong area is confined to one single formation, the Myobong Slate. Four major ore beds, which have an lateral extension over than 1 km and were not heavily subjected to spatial disturbance, are developed in the Myobong Formation. The original materials of the ore-comprising horizones were probably of either calcareous or silceous sediments. The four ore beds, especially in the case of Main ore bed, display both lateral and vertical zoning. Association quartz-mica-scheelite is predominant in the central, while association hornblende-quartz-diopside-scheelite, diopside-garnet and wollastonite-garnet are developed in this order towards the periphery of the ore beds. Petrologically, two phases of thermometamorphism are recognized. The first phase is represented by the association wollastonite-garnet and diopside-garnet, while the second phase by the association hornblende-quartz-diopside-scheelite and quartz-mica-scheelite. The associations of the second phase do constitute prodctive ore. The high background value of tungsten in the area surrounding the Sangdong mine reveals that the area can be considered a geochemical zone enriched in tungsten. Studies on the trace element patterns were carried out to draw useful criteria for the purpose of future geochemical exploration in the area. The increasing trend of the ratio Rb $({\times}1000)/K_2O$ of the Myobong Slate towards the known mineralization area proved to be indicative for the presence of tungsten mineralization.

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노년 남성의 발 유형 분류 -Size Korea의 3차원 측정 데이터를 이용하여- (The Classification of Elderly Men's Feet - With the Three-dimensional Body Scanner Data of Size Korea -)

  • 석혜정;박지은
    • 복식
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    • 제57권10호
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    • pp.50-59
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    • 2007
  • This study has been conducted to classify elderly men's feet with the three-dimensional body scanner data of Size Korea. It was intended to assist the manufacturing of the shoes that can appropriately perform the functions of feet, by providing the specific information about the shapes of elderly men's feet that are altered as a result of aging and shoe-wearing for a long time. The findings are as follows. 1. The investigations into the average and standard deviation of the measurements and index values for the elderly men's feet showed a large personal difference in the items of length and circumference. 2. The factors constituting the elderly men's feet were observed to be the size of foot width(Factor 1), the central angle of feet and the extension of toes(Factor 2), the size of ankle(Factor 3), the positions of lateral malleolus and pternion(Factor 4), and the position and size of medial malleolus(Factor 5). 3. The cluster analysis for the classification of elderly men's feet produced three types of them.