• 제목/요약/키워드: center selection

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GNFS를 위한 향상된 다항식 선택 기법 (Enhanced Polynomial Selection Method for GNFS)

  • 김수리;권지훈;조성민;장남수;윤기순;김창한;박영호;홍석희
    • 정보보호학회논문지
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    • 제26권5호
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    • pp.1121-1130
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    • 2016
  • RSA 암호 시스템은 가장 널리 사용되는 공개키 암호 알고리즘 중 하나이며, RSA 암호 시스템의 안전성은 큰 수의 인수분해의 어려움에 기반을 둔다. 따라서 RSA 암호 시스템의 합성수 n을 인수분해하려는 시도는 계속 진행 중에 있다. General Number Field Sieve는 현재까지 알려진 가장 빠른 인수분해 방법이고, RSA-704를 인수분해 하는데 사용된 소프트웨어인 CADO-NFS도 GNFS를 기반으로 설계되어 있다. 그러나 CADO-NFS는 다항식 선택 과정에서 입력된 변수로부터 항상 최적의 다항식을 선택하지 못하는 문제점이 있다. 본 논문에서는 CADO-NFS의 다항식 선택 단계를 분석하고 중국인의 나머지 정리와 유클리드 거리를 사용하여 다항식을 선택하는 방법을 제안한다. 제안된 방법을 이용하면 기존의 방법보다 좋은 다항식이 매번 선택되며, RSA-1024를 인수분해 하는데 적용할 수 있을 것으로 기대한다.

Exploring the molecular characteristics, detoxification functions, and immune responses of two glutathione S-transferases in redlip mullet (Liza haematochelia)

  • Jeongeun Kim;Welivitiye Kankanamge Malithi Omeka;Qiang Wan;Jehee Lee
    • Fisheries and Aquatic Sciences
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    • 제27권5호
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    • pp.314-328
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    • 2024
  • The mechanism for the elimination of xenobiotics undergoes three different phases of reactions in organisms. Among these, glutathione S-transferases (GSTs) are classified as phase II detoxification enzymes, catalyzing the conjugation of electrophilic substrates to glutathione or reduced hydroperoxides. This study aimed to investigate the molecular characteristics, detoxification functions, and immune responses of GST omega (LhGSTO1) and kappa (LhGSTK1) in redlip mullet. The open reading frames of LhGSTO1 (720 bp) and LhGSTK1 (687 bp) encoded proteins of 239 and 228 amino acids, respectively. Sequence analysis revealed that LhGSTO1 and LhGSTK1 possessed GSH-binding sites in their N-terminal domains. Substrate-binding sites in the C-terminal domain were exclusively identified in LhGSTO1. In the tissue-specific transcription profile analysis, both LhGSTO1 and LhGSTK1 were ubiquitously expressed in all tissues of healthy mullets. Temporal expression analysis of LhGSTO1 and LhGSTK1 in the blood showed that their expression was significantly modulated by polyinosinic:polycytidylic (poly I:C), lipopolysaccharide (LPS), and Lactococcus garvieae. Different chemical and cellular assays were performed to assess the detoxification and cellular protective abilities of the two proteins. A substrate specificity test using the recombinant proteins revealed that both proteins possessed specific activity toward 1-chloro-2,4-dinitrobenzene (CDNB). In the disk diffusion assay, the smallest clearance zones were observed for LhGSTO1 and LGSTK1 against CdCl2. In the cell protection assay, both LhGSTO1 and LhGSTK1 showed significant Cd detoxification ability compared to the control. Collectively, these results demonstrate that GST omega and kappa are involved in host defense against immune stimulants and xenobiotics in redlip mullet.

상호 확산 반응 중의 생성상 제어 (Product Phase Control During Interdiffusion Reactions)

  • 박준식;김지훈
    • 한국주조공학회지
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    • 제26권1호
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    • pp.27-33
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    • 2006
  • Phase evolutions involving nucleation stages together with diffusional growth have been examined in order to provide a guideline for determining rate limiting stages during phase evolutions. In multiphase materials systems in coatings, composites or multilayered structures, diffusion treatments often result in the development of metastable/intermediate phases at the reaction interfaces. The development of metastable phases during solid state interdiffusion demonstrates that the nucleation reaction can be one controlling factor. Also, the concentration gradient and the relative magnitudes of the component diffusivities provide a basis for a phase selection and the application of a kinetic bias strategy in the phase selection. For multicomponent alloy systems, the identification of the operative diffusion pathway is central to control phase formation. Experimental access to the nucleation and growth stage is discussed in thin film multi layers and bulk samples.

User Selection Algorithms for MU-MIMO Systems with Coordinated Beamforming

  • Maciel-Barboza, Fermin Marcelo;Soriano-Equigua, Leonel;Sanchez-Garcia, Jaime;Castillo-Soria, Francisco Ruben;Topete, Victor Hugo Castillo
    • ETRI Journal
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    • 제38권1호
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    • pp.62-69
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    • 2016
  • In this paper, we propose two novel user selection algorithms for multiuser multiple-input and multiple-output downlink wireless systems, in which both a base station (BS) and mobile stations (MSs) are equipped with multiple antennas. Linear transmit beamforming at the BS and receive combining at the MSs are used to avoid interference between users and find a better sum-rate capacity performance. An optimal technique for selecting users would entail an exhaustive search, which in practice becomes computationally complex for a realistic number of users. Suboptimal algorithms with low complexity are proposed for a coordinated beamforming scheme. Simulation results show that the performance of the proposed algorithms is better than that provided by previous algorithms and is very close to an optimal approach with reduced complexity.

T Cell Receptor Signaling That Regulates the Development of Intrathymic Natural Regulatory T Cells

  • Song, Ki-Duk;Hwang, Su-Jin;Yun, Cheol-Heui
    • IMMUNE NETWORK
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    • 제11권6호
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    • pp.336-341
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    • 2011
  • T cell receptor (TCR) signaling plays a critical role in T cell development, survival and differentiation. In the thymus, quantitative and/or qualitative differences in TCR signaling determine the fate of developing thymocytes and lead to positive and negative selection. Recently, it has been suggested that self-reactive T cells, escape from negative selection, should be suppressed in the periphery by regulatory T cells (Tregs) expressing Foxp3 transcription factor. Foxp3 is a master factor that is critical for not only development and survival but also suppressive activity of Treg. However, signals that determine Treg fate are not completely understood. The availability of mutant mice which harbor mutations in TCR signaling mediators will certainly allow to delineate signaling events that control intrathymic (natural) Treg (nTreg) development. Thus, we summarize the recent progress on the role of TCR signaling cascade components in nTreg development from the studies with murine model.

Significant Gene Selection Using Integrated Microarray Data Set with Batch Effect

  • Kim Ki-Yeol;Chung Hyun-Cheol;Jeung Hei-Cheul;Shin Ji-Hye;Kim Tae-Soo;Rha Sun-Young
    • Genomics & Informatics
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    • 제4권3호
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    • pp.110-117
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    • 2006
  • In microarray technology, many diverse experimental features can cause biases including RNA sources, microarray production or different platforms, diverse sample processing and various experiment protocols. These systematic effects cause a substantial obstacle in the analysis of microarray data. When such data sets derived from different experimental processes were used, the analysis result was almost inconsistent and it is not reliable. Therefore, one of the most pressing challenges in the microarray field is how to combine data that comes from two different groups. As the novel trial to integrate two data sets with batch effect, we simply applied standardization to microarray data before the significant gene selection. In the gene selection step, we used new defined measure that considers the distance between a gene and an ideal gene as well as the between-slide and within-slide variations. Also we discussed the association of biological functions and different expression patterns in selected discriminative gene set. As a result, we could confirm that batch effect was minimized by standardization and the selected genes from the standardized data included various expression pattems and the significant biological functions.

유전 알고리즘을 이용한 FCM 알고리즘의 초기 군집 중심 선택 (A initial cluster center selection in FCM algorithm using the Genetic Algorithms)

  • 오종상;정순원;박귀태
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 1996년도 추계학술대회 학술발표 논문집
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    • pp.290-293
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    • 1996
  • This paper proposes a scheme of initial cluster center selection in FCM algorithm using the genetic algorithms. The FCM algorithm often fails in the search for global optimum because it is local search techniques that search for the optimum by using hill-climbing procedures. To solve this problem, we search for a hypersphere encircling each clusters whose parameters are estimated by the genetic algorithms. Then instead of a randomized initialization for fuzzy partition matrix in FCM algorithm, we initialize each cluster center by the center of a searched hypersphere. Our experimental results show that the proposed initializing scheme has higher probabilities of finding the global or near global optimal solutions than the traditional FCM algorithm.

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Proton Exchange Membranes using Polymer Blends of PVA(Polyvinyl alcohol)/PSSA-MA(Polystyrene sulfonic acid-co-maleic acid)

  • Knag, Moon-Sung;Kim, Jong-Hak;Kim, Hyunyoo;Jongok Won;Moon, Seung-Hyeon;Kang, Yong-Soo
    • 한국막학회:학술대회논문집
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    • 한국막학회 2004년도 Proceedings of the second conference of aseanian membrane society
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    • pp.29-32
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    • 2004
  • Reduction of methanol crossover in proton exchange membranes (PEMs) can be achieved by 1) the selection of materials, 2) the morphology control, and 3) the adequate crosslinking [1, 2]. The selection of polymer matrix of PEM for direct methanol fuel cells (DMFCs) is very important because the proton conductivity and methanol permeability are largely dependent upon the properties of polymers.(omitted)

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