• Title/Summary/Keyword: center of resistance

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Experimental Research of Lost-wax Casting: Gilt-Bronze Pensive Bodhisattva (밀랍주조법을 활용한 청동반가사유상 복원 연구)

  • Yun, Yong-Hyun;Cho, Nam-Chul;Doh, Jung-Mann
    • Journal of Conservation Science
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    • v.36 no.2
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    • pp.123-142
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    • 2020
  • We attempted an experimental study of lost-wax casting to reconstruct the Gilt-bronze pensive Bodhisattva; The main object we aimed to reconstruct was the Korean national treasure No.83, Gilt-bronze pensive Bodhisattva(Maitreya); thus, we scientifically analyzed and measured the alloy ratio and casting method. Initially, the alloy ratio we used during the preliminary experiment was Cu:Sn:Pb = 95.5:4.0:0.5; we then increased tin and lead by 2.5% to consider vaporization during the main experiment. After applying lost-wax casting, we realized that 30% rosin contributed to proper hardness after the wax hardness experiment. The microstructure revealed normal casting character(α-Cu, δ), and the results of the chemical analysis are identical to those of previous studies. The analysis of the mold suggests the presence of quartz powder for structural stability and fire-resistance along with other organic materials whose contribution is still unknown. We expect that our research will serve to provide basic data for advanced studies in the future.

Can Hinokitiol Kill Cancer Cells? Alternative Therapeutic Anticancer Agent via Autophagy and Apoptosis (Hinokitiol에 의해 유도된 Autophagy 및 Apoptosis에 의한 대체 항암요법 연구)

  • Lee, Tae Bok;Jun, Jin Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.2
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    • pp.221-234
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    • 2019
  • Cancer is genetically, metabolically and infectiously induced life threatening disorder showing aggressive growing pattern with invasive tendency. In order to prevent this global menace from jeopardizing human life, enormous studies on carcinogenesis and treatment for chemotherapy resistance have been intensively researched. Hinokitiol (${\beta}$-thujaplicin) extracted from heart wood of cupressaceous is a well-known bioactive compound demonstrating anti-inflammation, anti-bacteria and anti-cancer effects on several cancer types via apoptosis and autophagy. This study proposed that hinokitiol activates transcription factor EB (TFEB) nuclear translocation for autophagy and lysosomal biogenesis regardless of nutrient condition in cancer cells. Mitophagy and ${\beta}$-catenin translocation into the nucleus under treatment of hinokitiol on non-small cell lung cancer (NSCLC) cells and HeLa cells were investigated. Hinokitiol exerted cytotoxicity on HeLa and HCC827 cells; moreover, artificially induced autophagy by overexpression of TFEB granted imperfect sustainability onto HeLa cells. Taken together, hinokitiol is the prominent autophagy inducer and activator of TFEB nuclear translocation. Alternative cancer therapy via autophagy is pros and cons since the autophagy in cancer cells is related to prevention and survival mechanism depending on nutrition. To avoid paradox of autophagy in cancer therapy, fine-tuned regulation and application of hinokitiol in due course for successful suppressing cancer cells are recommended.

Development of Permit Vehicle Classification System for Bridge Evaluation in Korea (허가차량 통행에 대한 교량의 안전성 평가를 위한 허가차량 분류 체계 개발)

  • Yu, Sang Seon;Kim, Kyunghyun;Paik, Inyeol;Kim, Ji Hyeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.845-856
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    • 2020
  • This study proposes a bridge evaluation system for indivisible permit vehicles such as hydraulic cranes. The permit loads for the bridge evaluation are divided into three categories: routine permit loads, special permit 1 loads, and special permit 2 loads. Routine permit and special permit 1 vehicles are allowed to cross a bridge with normal traffic. For these two permits, the standard lane model in the Korean Highway Bridge Design Code was adopted to consider normal traffic in the same lane. Special permit 2 vehicles are assumed to cross a bridge without other traffic. Structural analyses of two prestressed-beam bridges and two steel box girder bridges were conducted for the proposed permit loads. The rating factors of the four bridges for all permit loads were calculated as sufficiently large values for the moment and shear force so that crossing the bridges can be permitted. A reliability assessment of the bridges was performed to identify the reliability levels for the permit vehicles. It was confirmed that the reliability level of the minimum required strength obtained by the load-resistance factors yields the target reliability index of the design code for the permit vehicles.

Structural Design And Analysis of Haeundae Doosan We've The Zenith (해운대 두산 위브 더 제니스 구조설계)

  • Park, Ki-Hong;Park, Suk-Jin
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.93-98
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    • 2008
  • Haeundae Doosan We've The Zenith project is adjacent to Suyoung-bay, now it is in the process of excavation and foundation work. The main use of the tower is residence which height is 300m and 80 floor, the highest residential reinforced concrete building through the Orient. It is comprised of 3 high- rised buildings and 1 low-rised building, the basement is 230m wide and 200m length sized mass structure. The lateral resistance system is acted effectively against the lateral load and satisfactorily against the wind vibration by the 4 direction extension of the center core wall($700{\sim}800mm$ thickness) and reinforced concrete column set around the slab. Flat-plate slab system(250mm thickness) is adjusted for the slab system and it enables effective work process and shortening the working term by minimizing the ceiling height and not needing to install perimeter beam and drop panel. The strength and serviceability of the structure is able to be monitored and estimated constantly through the health monitoring system during the construction and after the construction.

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Accelerated Life Prediction on Tensile Strength of Oil Resistance HNBR (내유성 HNBR 고무의 인장강도 성능에 대한 가속수명예측)

  • Kim, Kyung Pil;Lee, Yong Seok;Yeo, Yong Heon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.11
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    • pp.233-238
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    • 2020
  • Although the interest in NBR has been increasing due to the recent developments of the aerospace sector, there are few reports on HNBR's aeronautical oil, particularly evaluations of the accelerated life of harsh factors. In this study, the tensile strength was adopted as a performance evaluation factor to evaluate the accelerated life of HNBR used in the aviation field. The accelerated stress factor affecting the performance-aging characteristics was defined as temperature. The acceleration stress factor was determined to be temperature, and the result of measuring the tensile strength change over time. The sample for the acceleration condition was taken out of the oven for a certain period and left at room temperature for 24 hours. The dumbbell type 3 specimens were manufactured according to the standard specified in KS M 6518 and were measured the tensile strength, a factor in accelerated life evaluations. The activation energy was 0.895, and the shape parameter was 1.152 using the Arrhenius model. The characteristic life obtained from the tensile strength of the HNBR specimen immersed in aviation oil at 20℃ was 272,256 hours; the average life was 258,965 hours, and the B10 life was 38,624 hours.

Field emission properties of Ag-Cu-alloy coated CNT-emitters (Ag-Cu합금 코팅된 탄소나노튜브의 전계방출 특성)

  • Lee, Seung-Youb;Ryul, Dong-Heon;Hong, Jun-Yong;Yeom, Min-Hyeng;Yang, Ji-Hoon;Choi, Won-Chel;Kwon, Myeng-Hoi;Park, Chong-Yun
    • Journal of the Korean Vacuum Society
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    • v.16 no.4
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    • pp.291-297
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    • 2007
  • The field emission properties of CNT-emitters coated with Ag-Cu alloy have been investigated. The vertical aligned multi-walled CNTs were synthesized by dc-plasma enhanced chemical vapor deposition (dc-PECVD) and the Ag-Cu alloy was coated by using dc-magnetron sputter. The morphology of alloy-coated and un-coated CNT-emitters was observed by using SEM and their field emission properties were also measured. Annealing the AgCu-coated CNTs at temperature more than ${\sim}700^{\circ}C$, the Ag-Cu alloy was diffused to and aggregated on the top of the CNT as a Q-tip. A significant progress on the field emission was not observed with coating Ag-Cu alloy on the CNTs, but a certain improvement in a resistance against oxygen gas was made confirmation. It seems to be due to inertness of Ag-Cu alloy on the CNTs.

Box-Wilson Experimental Design-based Optimal Design Method of High Strength Self Compacting Concrete (Box-willson 실험계획법 기반 고강도 자기충전형 콘크리트의 최적설계방법)

  • Do, Jeong-Yun;Kim, Doo-Kie
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.5
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    • pp.92-103
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    • 2015
  • Box-Wilson experimental design method, known as central composite design, is the design of any information-gathering exercises where variation is present. This method was devised to gather as much data as possible in spite of the low design cost. This method was employed to model the effect of mixing factors on several performances of 60 MPa high strength self compacting concrete and to numerically calculate the optimal mix proportion. The nonlinear relations between factors and responses of HSSCC were approximated in the form of second order polynomial equation. In order to characterize five performances like compressive strength, passing ability, segregation resistance, manufacturing cost and density depending on five factors like water-binder ratio, cement content, fine aggregate percentage, fly ash content and superplasticizer content, the experiments were made at the total 52 experimental points composed of 32 factorial points, 10 axial points and 10 center points. The study results showed that Box-Wilson experimental design was really effective in designing the experiments and analyzing the relation between factor and response.

Retheorising Civil Society in State-Civil Society Partnership in Welfare : A Critical Review of the Partnership Literature (국가-시민사회 복지파트너십에서 시민사회단체의 역할 : 세 가지 이론적 관점을 중심으로)

  • Kim, Suyoung
    • Korean Journal of Social Welfare Studies
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    • v.44 no.1
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    • pp.267-302
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    • 2013
  • In recent years, partnership has become a central strategy for welfare provision worldwide. Particularly, civil society organisations have obtained considerable attention as the most accountable and democratic partner for public welfare delivery. Yet the mainstreaming of civil society into welfare policies challenges the conventional nature of civil society as an independent sector, and brings into critical question, how the political position of the civil society sector could be redefined in the new era of multi-sectoral partnership. The purpose of this study is to explore the current debates of state-civil society partnership and to propose three theoretical viewpoints (i.e. the mainstream, critical and alternative perspectives) regarding the role of the civil society sector in partnership. In doing so, this article introduces the key literature and scholars in partnership debates and provides analytical frameworks that researchers can use in examining state-civil society partnership cases.

A numerical study of the effects of the ventilation velocity on the thermal characteristics in underground utility tunnel (지하공동구 터널내 풍속 변화에 따른 열특성에 관한 수치 해석적 연구)

  • Yoo, Ji-Oh;Kim, Jin-Su;Ra, Kwang-Hoon
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.1
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    • pp.29-39
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    • 2017
  • In this research, thermal design data such as heat transfer coefficient on the wall surface required for ventilation system design which is to prevent the temperature rise in the underground utility tunnel that three sides are adjoined with the ground was investigated in numerical analalysis. The numerical model has been devised including the tunnel lining of the underground utility tunnel in order to take account for the heat transfer in the tunnel walls. The air temperature in the tunnel, wall temperature, and the heating value through the wall based on heating value(117~468 kW/km) of the power cable installed in the tunnel and the wind speed in the tunnel(0.5~4.0 m/s) were calculated by CFD simulation. In addition, the wall heat transfer coefficient was computed from the results analysis, and the limit distance used to keep the air temperature in the tunnel stable was examined through the research. The convective heat transfer coefficient at the wall surface shows unstable pattern at the inlet area. However, it converges to a constant value beyond approximately 100 meter. The tunnel wall heat transfer coefficient is $3.1{\sim}9.16W/m^2^{\circ}C$ depending on the wind speed, and following is the dimensionless number:$Nu=1.081Re^{0.4927}({\mu}/{\mu}_w)^{0.14}$. This study has suggested the prediction model of temperature in the tunnel based on the thermal resistance analysis technique, and it is appraised that deviation can be used in the range of 3% estimation.

Risk Factors for Primary Multidrug Resistant Tuberculosis (초회다제내성 결핵의 위험요인)

  • Min, Jinhong;Park, Keeho;Whang, Suhee;Kim, Jinhee
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.6
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    • pp.600-605
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    • 2005
  • Background : Primary multidrug-resistant tuberculosis is defined as Mycobacterium tuberculosis isolates that are resistant to at least isoniazid and rifampin in never-been-treated tuberculosis patients, and this malady is caused by the transmission of a resistant strain from one patient, who is infected with a resistant Mycobacterium tuberculosis strain, to another patient. The prevalence of primary multidrug-resistant tuberculosis could be a good indicator of the performance of tuberculosis control programs in recent years. We conducted a case-control study to identify the risk factors for primary multidrug-resistant tuberculosis. Methods : From January 1, 2001 to, June 30, 2003, by conducting prospective laboratory-based surveillance, we identified 29 hospitalized patients with P-MDRTB and these patients constituted a case group in this study. The controls were represented by all the patients with culture-confirmed drug susceptible tuberculosis who were admitted to National Masan Hospital during the same study period. The odds ratios for the patients with primary multidrug-resistant tuberculosis, as compared with those of the patients with drug susceptible tuberculosis, were calculated for each categorical variable with 95% confidence intervals. Results : Multivariate logistic regression showed that the presence of diabetes mellitus (odds ratio 2.68; 95% confidence interval, 1.05-6.86) was independently associated with having primary multidrug-resistant tuberculosis. Conclusion : This study has shown that diabetes mellitus might be one of the risk factors for primary multidrug-resistant tuberculosis.