• 패션비즈니스
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• 제15권6호
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• pp.85-100
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• 2011

The objective of this study was to analyze body measurements, BMI and body type according to age in the male and female groups based on 3D scan body measurement data of adult men and women in their 20's~30's and to provide basic information usable in the clothing and fashion industry. For this purpose, we analyzed 3D scan body measurement data of 848 adults measured in the 6th Size Korea project and the results were as follows. First, there were differences in 3D scan body measurements according to age in the male and female groups, and in general the measurements of the height items were larger in younger adults and the measurements of the circumference, breadth and depth items were larger in older ones. Second, there were differences in 3D scan body measurements according to BMI in the male and female groups, and in general body measurements were largest in the obesity group and lowest in the underweight group. Third, BMI was different according to gender and in general BMI was higher in men and obesity and overweight were more frequent in men than in women. Moreover, BMI was significantly different according to age and was higher in the 30's than in the 20's. Fourth, the mean difference in the drop and lower drop values according to age in the male and female groups was significant, and the drop and lower drop values were lower in the 30's than in the 20's. These results are considered meaningful as data for the development of clothing size systems, patterns and grading in the areas of clothing and fashion targeting consumers in their 20's~30's.

• 한국가정과교육학회지
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• 제22권4호
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• pp.65-75
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• 2010

본 연구는 청소년들이 가지고 있는 다이어트에 대한 태도를 파악하고 올바른 다이어트를 실행하는데 도움을 주기 위한 기초자료를 제공하기 위하여 인구통계학적 특성과 체질량지수, 다이어트에 대한 관심도, 다이어트에 대한 인식도, 자아존중감, 신체이미지, 체형에 대한 부모, 친구, 대중매체 영향요인이 다이어트 실행에 미치는 영향력에 대하여 살펴보았다. 본 연구의 자료는 경북지역의 고등학생으로부터 설문지를 통해 수집되었으며, 최종 360부의 설문지가 최종분석자료로 이용되었다. 다이어트 실행집단과 비실행집단 간의 체질량지수, 다이어트에 대한 관심도, 다이어트에 대한 인식도, 자아존중감, 신체이미지, 체형에 대한 부모, 친구, 대중매체 영향요인을 비교해보면, 다이어트 실행집단은 비실행집단에 비해 체질량지수가 높고 다이어트에 대한 관심이 많으며 다이어트에 보다 긍정적으로 인식하고 있고 자아존중감과 신체이미지에 대한 만족도가 낮으며 체형에 대한 부모, 친구와 대중매체의 영향을 많이 받고 있는 것으로 나타났다. 또한 로지스틱 회귀분석 결과, 체질량지수, 다이어트에 대한 인식도, 신체이미지, 체형에 대한 친구의 영향, 체형에 대한 대중매체의 영향이 다이어트 실행 여부에 유의한 것으로 나타났다.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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• pp.45-45
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• 2003

Human papillomavirus type 16(HPV16) has been known to the major factor for the development of uterine cervical carcinomas. We have extended these studies to investigate the in vivo activities of HPV-16 E6/E7 when expressed in squamous epithelia of transgenic mice. Grossly, hK14HPV16E6/E7 transgenic mice had multiple phenotypes, including wrinkled skin that was apparent prior to the appearance of hair on neonates, thickened ears, and loss of hair in adults. In the transgenic mice, the wrinkled skin phenotype on the body and legs died at the age of 3∼4 weeks. Histological analysis of demonstrated that E6/E7 causes epidermal hyperplasia in multiple transgenic lineages with high penetrance. This epithelial hyperplasia was characterized by an expansion of the proliferating compartment and an expansion of the keratinocyte and was associated with hyperkeratosis. These transgenic mice expressed E6/E7 transgene mainly in skin, heart, pancreas and kidney. Hyperplasia was found at the skin. The enzyme activities of GR, GPx and CuZnSOD were measured from the transgene cause keratinocyte at the skin. The specific enzyme activities were significantly higher in transgenic mice skin compared to the normal mice skin. Thus these transgenic mice may be useful for the develpment of antioxidant enzymes or other therapies for HPV-associated hyperkeratosis.

• Genomics & Informatics
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• 제9권4호
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• pp.152-160
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• 2011

Hypertension is the major factor of most death and high blood pressure (BP) can lead to stroke, myocardial infarction and cardiac failure. Moreover, hypertension is strongly correlated with body mass index (BMI). Although the exact causes of hypertension are still unclear, some of genetic loci were discovered from genome-wide association study (GWAS). Therefore, it is essential to study genetic variation for finding more genetic factor affecting hypertension. The purpose of our study is to conduct a CNV association study for hypertension-related traits, BP and BMI, in Korean individuals. We identified 2,206 CNV regions from 3,274 community-based Korean participants using the Affymetrix Genome-Wide Human SNP Array 6.0 platform and performed a logistic regression analysis of CNVs with two hypertension-related traits, BP and BMI. Moreover, the 4,692 participants in an independent cohort were selected for respective replication analyses. GWAS of CNV identified two loci encompassing previously known hypertension-related genes: LPA (lipoprotein) on 6q26, and JAK2 (Janus kinase 2) on 9p24, with suggestive p-values (0.0334 for LPA and 0.0305 for JAK2 ). These two positive findings, however, were not evaluated in the replication stage. Our result confirmed the conclusion of CNV study from the WTCCC suggesting weak association with common diseases. This is the first study of CNV association study with BP and BMI in Korean population and it provides a state of CNV association study with common human diseases using SNP array.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.396.3-397
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• 2002

Because of the differences in biological and pharmacological properties between enantiomers of chiral acidic non-steroidal antiinflammatory drugs (NSAIDs) in human body. accurate determinations of their optical purities have been in great need. Racemic ibuprofen. tiaprofen. suprofen. flubiprofen and napoxen were reacted with (1R. 28. 5R)-(－)-menthol to convert them to corresponding diastereomeric (1R. 2S. 5R)-(－ )-menthyl esters. (omitted)

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.2654-2659
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• 2003

In this paper, we present biomimetic hopping strategy which is more human-like for legged robot through stiffness modulation. Stiffness value is calculated from the motion of body center of gravity. This method enable to reduce impact force on touch-down, adaption on ground stiffness change and height modulation. Simple selected models will be used to validate this method. For general model, singular perturbation is used for control and simulation using stiffness modulation is presented.

• 대한핵의학회지
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• 제36권1호
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• pp.46-52
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• 2002

Whole-body positron emission tomography (PET) imaging with 18-F deoxyglucose (FDG) is a molecular imaging modality that detects metabolic alteration in tumor cells. In various human cancers, FDG-PET shows a potential clinical benefit in screening, tumor characterization, staging, therapeutic follow-up and detecting recurrence. In gynecologic cancers, FDG-PET is also known to be effective in characterization of adnexal masses, detection of recurrence, and lymph node invasion. This review discusses the clinical feasibility and future clinical application of this imaging modality in patients with cervical cancer, ovarian cancer, and other gynecologic cancers.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2002년도 동계연구발표회 논문개요집
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• pp.88-89
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• 2002

Studies on drug delivery using nano-size particles of magnetic fluid and hyperthermia have been performed by some researchers [1] because interests in human health increased according to industry development. However, there are few studies on systems which can accurately control delivery of the magnetic fluids to a diseased part of body [2]. In this study, Cu-added magnetic ferrofluid was prepared and the external magnetic field system was designed for drug localization.

• 한국생활과학회지
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• 제23권6호
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• pp.1191-1204
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• 2014

Even though a Han-bok, or traditional Korean costume, should be inherited since it is invaluable part of our culture, research on Han-bok is scarce. Since the development of a Jeogori pattern, the upper garment of Korean traditional clothes, is done mostly based on the chest size, the design does not completely consider on wearer's body shape. Moreover, unless made by an expert, trial and error is almost always necessary to improve the fit of the clothes. In this research, a Jeogori pattern was suggested that improves the fit based on the shape of the upper back(straight or bent) of a female in her late 20s who often wears a Han-bok and is comfortable when moving. Using a 3D virtual clothing system, the optimum pattern was selected based on the body shape. The final selection was made, and each subjects tried the garment on to evaluate the comfort when moving, along with its appearance, based on a seven point Likert scale. As a result, for a straight body shape, the optimum ease for the front bust width was 2.5cm, and that for the back bust width was 2.0cm. The optimum center back dart was 1.0cm. The optimum Geodae width was 7.6cm, and the optimum back Geodae point was 2.0cm. For the bent body shape, the optimum ease for the front and back bust was 2.0cm. The optimum Geodae width was 8.4cm, and the optimum back Geodae point was 1.5cm. Furthermore, if the Hwajang slope was set at half of the vertical distance between the laterals of the neck and shoulder, a fitted silhouette appeared, which is preferred nowadays. In the appearance evaluation, the final pattern designed in this research received higher scores than the original design(straight; p<.001, bent; p<.05). The results of the evaluation of the comfort when moving also showed higher scores for the final pattern that was designed.

• Toxicological Research
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• 제17권
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• pp.25-35
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• 2001

In 1990, Tolerable Daily Intake (TDI) of 10 pg TCDD/kg/day for dioxins based on carcinogenicity and reproductive toxicity was determined by WHO/EURO, that resulted in the establishment of TDIs in other countries. In Japan, Ministry of Health and Welfare and Environment Agency, respectively established the TDI of 10 pg TCDD/kg/day and Health Risk Assessment Index of 5 pg TCDD/kg/day in 1996. Accumulation of new scientific data, especially by molecular toxicology since 1990, resulted in the reevaluation of TDI by WHO-ECEH and IPCS in May, 1998. At this meeting, it was stressed that \circled1 toxic effects of dioxin is mediated through Ah-receptor in both animals and humans, \circled2 use of ebody burdeni concept is better than the use of traditional NOAEL/UF approach, \circled3 inclusion of coplanar PCBs in the TDI by the use of new WHO-TEF. LOAELs (0.16~200 ng TCDD/kg/day) obtained from reproductive toxicity and immunotoxicity in rats, and neurobehavioral toxicity and induction of endometriosis in rhesus monkeys are calculated to be the body burden of 10~50 ng TCDD/kg that is 14~37 pg TEQ/kg/day as human daily intake. Finally TDI of 1~4 pg TEQ/kg/day was established by applying the UF of 10. In Japan, reproductive toxicity and immunotoxicity in rats were used to obtain LOAELs (100~200 ng TCDD/kg/day). Finally TDI of 4 pg TEQ/kg/day was established in June 1999 by applying the UF of 10 to human daily intake of 43.6 pg TEQ/kg/day which corresponds to the body burden of 86 ng TCDD/kg.