• Journal of Gastric Cancer
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• v.24 no.1
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• pp.69-88
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• 2024

This review comprehensively examines the diverse spectrum of gastric cancers, focusing on unusual or uncommon histology that presents significant diagnostic and therapeutic challenges. While the predominant form, tubular adenocarcinoma, is well-characterized, this review focuses on lesser-known variants, including papillary adenocarcinoma, micropapillary carcinoma, adenosquamous carcinoma, squamous cell carcinoma (SCC), hepatoid adenocarcinoma, gastric choriocarcinoma, gastric carcinoma with lymphoid stroma, carcinosarcoma, gastroblastoma, parietal cell carcinoma, oncocytic adenocarcinoma, Paneth cell carcinoma, gastric adenocarcinoma of the fundic gland type, undifferentiated carcinoma, and extremely well-differentiated adenocarcinoma. Although these diseases have different nomenclatures characterized by distinct histopathological features, these phenotypes often overlap, making it difficult to draw clear boundaries. Furthermore, the number of cases was limited, and the unique histopathological nature and potential pathogenic mechanisms were not well defined. This review highlights the importance of understanding these rare variants for accurate diagnosis, effective treatment planning, and improving patient outcomes. This review emphasizes the need for ongoing research and case studies to enhance our knowledge of these uncommon forms of gastric cancer, which will ultimately contribute to more effective treatments and better prognostic assessments. This review aimed to broaden the pathological narrative by acknowledging and addressing the intricacies of all cancer types, regardless of their rarity, to advance patient care and improve prognosis.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.50 no.1
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• pp.49-55
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• 2024

Neurofibromatosis type 1 (NF1) is an autosomally dominant tumor suppressor syndrome and multisystem disease. Central giant-cell granulomas (CGCGs) can be seen in patients with NF1. A 21-year-old female was diagnosed with two CGCGs, one in the mandible and then one in the maxilla, in a 7-year period. Increased incidence of CGCGs in NF1 patients was thought to be caused by an underlying susceptibility to developing CGCG-like lesions in qualitatively abnormal bone, such as fibrous dysplasia. However, germline and somatic truncating second-hit mutations in the NF1 gene have been detected in NF1 patients with CGCGs, validating that they are NF1-associated lesions. Oral manifestations in patients with NF1 are very common. Knowledge of these manifestations and the genetic link between NF1 and CGCGs will enhance early detection and enable optimal patient care.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.50 no.3
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• pp.134-139
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• 2024

We systematically reviewed the literature on the co-occurrence of squamous cell carcinoma (SCC) and Warthin's tumor (WT), thought to be quite rare, to help reduce misdiagnosis and improve treatment planning. For this systematic review, we searched for articles in the Web of Science and PubMed databases, analyzed relevant studies for forward and backward citations, and identified only articles reporting on the "co-occurrence" of WT and SCC. Of the 237 studies identified, 12 comprising 18 patients met the inclusion criteria, to which we added one study from our institution. Most WTs were associated with SCC in the parotid gland or cervical lymph nodes. Most patients (89.5%) underwent selective or radical neck dissection due to identification of lesions separate from the primary SCC. Despite its frequent co-occurrence with other neoplasms, WT in the parotid or cervical lymph nodes tends to be misdiagnosed as a metastatic node when SCC is observed as the primary tumor. Factors to consider in diagnosis and neck management include identification of an association other than growth or development by lymphangiogenesis and whether the patient is a smoker, a strong risk factor.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2573-2577
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• 2016

Objective: The aim of this study was to determine a method of dose prescription that minimizes normal tissue irradiation outside the planning target volume (PTV) during stereotactic body radiotherapy (SBRT) for patients with non-small cell lung cancer. Methods: Previous research and patients with typical T1 lung tumors with peripheral lesions in the lung were selected for analysis. A PTV and several organs at risk (OARs) were constructed for the dose calculated; six treatment plans employing intensity modulated radiotherapy (IMRT) were produced, in which the dose was prescribed to encompass the PTV, with the prescription isodose level (PIL) set at 50, 60, 70, 80, 90 or 95% of the isocenter dose. Additionally, four OARs around the PTV were constructed to evaluate the dose received in adjacent tissues. Results: The use of higher PILs for SBRT resulted in improved sparing of OARs, with the exception of the volume of lung treated with a lower dose. Conclusions: The use of lower PILs is likely to create significant inhomogeneity of the dose delivered to the target, which may be beneficial for the control of tumors with poor conformity indices.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.10
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• pp.1833-1839
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• 2017

Korea Railway is enhancing the railway wireless communication system from VHF and TRS which have been used for 100 years to LTE-R starting with Ministry of Science and ICT's allocation of Integrated Public Network Frequency on December 2014. LTE-R has advantages on technology performance, also on ease of evolution based on standardization compared to existing technologies. However there are few problems that need to be solved to provide stable railway wireless services in the future. Due to national spectrum policy, LTE-R has frequency interference with Integrated Public Networks (PS-LTE, LTE-M ) and UHD-TV which was commercialized in 2017. This paper introduces performance changes caused by interferences which were founded from the test bed in Wonju~Gangneung LTE-R project and the result of RAN-Sharing. In addition, this paper suggests the standard for LTE-R cell planning in the case of sharing the Integrated Public Network Frequency by analyzing the changes of designed link-budget factor based on the test result.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.600-613
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• 2018

The purpose of this research was to introduce a network analysis method for analyzing the recent trend of the flexible solar cell using a scholarly database. Based on the five years from 2013 to 2017, we used centrality analysis of research papers via measurement of degree centrality, closeness centrality, and betweenness centrality. The results of network analysis show that cell has a centrality value above 0.8, which means that cell is connected with 80% of the total keywords, so it is recognized as the center of flexible solar cell research. The analysis results also indicate that perovskite and copper indium gallium diselenide (CuInGaSe2, or CIGS) are the center of the subgroup for cell. We recognize that the result refers to recent new technology called the CIGS/perovskite tandem solar cell. We hope that the network analysis method will be the appropriate and precise tool for technology and research planning via elaboration and optimization.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5355-5360
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• 2013

Background: Clarifying the prognostic impact of histological type is an essential issue that may influence the treatment and follow-up planning of newly diagnosed cervical cancer cases. This study aimed to evaluate the prognostic impact of histological type on survival and mortality in patients with cervical squamous cell carcinoma (SCC), adenocarcinoma (ADC) and small cell neuroendocrine carcinoma (SNEC). Materials and Methods: All patients with cervical cancer diagnosed and treated at Chiang Mai University Hospital between January 1995 and October 2011 were eligible. We included all patients with SNEC and a random weighted sample of patients with SCC and ADC. We used competing-risks regression analysis to evaluate the association between histological type and cancer-specific survival and mortality. Results: Of all 2,108 patients, 1,632 (77.4%) had SCC, 346 (16.4%) had ADC and 130 (6.2%) had SNEC. Overall, five-year cancer-specific survival was 60.0%, 54.7%, and 48.4% in patients with SCC, ADC and SNEC, respectively. After adjusting for other clinical and pathological factors, patients with SNEC and ADC had higher risk of cancer-related death compared with SCC patients (hazard ratio [HR] 2.6; 95% CI, 1.9-3.5 and HR 1.3; 95% CI, 1.1-1.5, respectively). Patients with SNEC were younger and had higher risk of cancer-related death in both early and advanced stages compared with SCC patients (HR 4.9; 95% CI, 2.7-9.1 and HR 2.5; 95% CI, 1.7-3.5, respectively). Those with advanced-stage ADC had a greater risk of cancer-related death (HR 1.4; 95% CI, 1.2-1.7) compared with those with advanced-stage SCC, while no significant difference was observed in patients with early stage lesions. Conclusion: Histological type is an important prognostic factor among patients with cervical cancer in Thailand. Though patients with SNEC were younger and more often had a diagnosis of early stage compared with ADC and SCC, SNEC was associated with poorest survival. ADC was associated with poorer survival compared with SCC in advanced stages, while no difference was observed at early stages. Further tailored treatment-strategies and follow-up planning among patients with different histological types should be considered.

• Journal of Energy Engineering
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• v.18 no.4
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• pp.230-238
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• 2009

We study about small gas engine and fuel cell CHP (Combined Heat and Power) as the technologies for energy conservation and $CO_2$ emissions reduction. Korea government plans to use them in near future. This study quantitatively analyzed energy consumption and $CO_2$ emissions reduction potential of small CHP instead of existing electric power plant (coal steam, combined cycle and oil steam) using LEAP (Long-range Energy Alternative Planning system) as energy-economic model. Three future scenarios are discussed. In every scenario similar condition for each CHP is used. Alternative scenario I: about 6.34% reduction in $CO_2$ emissions is observed in 2019 due to increase in amount of gas engine CHP and fuel cell CHP while coal use in thermoelectric power plant is almost stagnant. In alternative scenario II: a small 0.8% increase in $CO_2$ emission is observed in 2019 keeping conditions similar to alternative scenario I but using natural gas in combined cycle power plant instead of coal. During alternative scenario II overall $CO_2$ emission reduction is observed in 2019 due to added heat production from CHP. Alternative scenario III: about 0.8% reduction in $CO_2$ emissions is observed in 2019 using similar CHP as AS I and AS II. Here coal and oil are used in thermoelectric power plant but the quantity of oil and coal is almost constant for next decade.

• Journal of Advanced Navigation Technology
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• v.9 no.1
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• pp.71-78
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• 2005

Nowadays, the demand of HPI(High-speed Portable Internet) has been gradually increased to support the various services of high speed wire line internet such as xDS. HPI can support high speed internet in anyplace, anytime. For successful development of HPI, the performance should be evaluated according to the cell size and/or the number of users and cell design should be carried out based on these criteria. The previous cellular systems using CDMA technique focus on the establishment of link based on power control but HPI systems consider the QoS (Quality of Service) and its performance based on the scheduling technique. The results from the system level simulation show that the throughput is sensitive to the cell size and the number of users has little impact on it. Moreover, the variation of service delay is more sensitive to the number of users but less to the cell size.

• Land and Housing Review
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• v.11 no.1
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• pp.87-94
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• 2020

To implement the planning of zero-energy buildings, their energy performance must be improved, and renewable energy applications must also be included. To accelerate the use of renewable energies in such buildings, BIPVs should be actively used in windows and on roofs. Window-type BIPVs are being developed in various forms depending on the size, composition, area ratio of the window, specification of glass, and so on. To analyze the applicability of various solar cells as window-type BIPVs, in this study, we evaluated their applicability, at the current development level, by analyzing the indoor illuminance, heat gain and heat loss; the cooling, heating, and lighting energy levels; and the generation performance of the various solar cells. To enhance the future applicability of window type BIPV, we analyze the overall energy performance of the building, according to changes in visible light transmittance and generation efficiency. The main research results are as follows. The area ratios above the standard illuminance, based on the window type and according to the VLT, were in order of low-e glazing, a-Si window, DSSC window, and c-Si window. The heat gain of the semi-transparent solar cell winodw was remarkably low. The energy consumption of buildings was highest in the order of c-Si window, DSSC window, a-Si window, and clear low-e window. However, in the case of including the power generation performance of the solar cell, the energy consumption was found to be high in order of DSSC window, c-Si window, a-Si window, and clear low-e window. In the future, if a window-type BIPV is developed, we believe that improvement in power generation performance and improvement in visible light transmittance will be needed.