• Korean Journal of Biological Psychiatry
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• v.28 no.2
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• pp.50-57
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• 2021

Objectives Clozapine is the most effective atypical antipsychotic agent for the treatment-resistant schizophrenia (TRS), however, only 40%-70% of TRS patients respond to clozapine. Moreover, TRS encompasses various symptom dimensions. Therefore, augmentation with other medications for clozapine is frequently applied. However, the prescription pattern of clozapine and combined medications in Korea is yet to be examined. This study aims to investigate the maintenance treatment pattern of clozapine and augmentation agents in one Korean tertiary hospital. Methods The patients with schizophrenia spectrum disorders under clozapine maintenance, defined as one-year clozapine continuation, were subjected for analysis. Medication data at one-year time-point after clozapine initiation was extracted and analyzed. Results Among total 2897 patients having clozapine prescription experience from January 2000 to December 2018, 1011 patients were on clozapine maintenance. The mean age of clozapine initiation was 30.2 ± 11.3 years, and the maintenance dose of clozapine was 217.8 ± 124.3 mg/day. Combination rate of antipsychotics, mood stabilizers, and antidepressants were 43.5%, 25.3%, 38.6%, respectively. Most frequently prescribed drugs in each category were aripiprazole, valproate, and sertraline. Olanzapine equivalent dose of combined antipsychotics was 10.4 ± 7.7 mg/day. Male patients were prescribed higher dose of combined antipsychotics and higher rate of antidepressants. Female patients had later onset of clozapine prescription. Patients with two or more combined antipsychotics were prescribed higher dose of clozapine and higher rate of antidepressants compared to patients with one combined antipsychotic. Conclusions Taken together, among the patients taking clozapine, a substantial rate of patients were under polypharmacy. The present findings based on the real-world prescription pattern could provide the valuable clinical information on the treatment of TRS-related conditions.

• Korean Journal of Adult Nursing
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• v.25 no.5
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• pp.504-514
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• 2013

Purpose: This study was to describe the process of healthy dieting and develop a substantive theory that explains lifestyle in obese male college students. Methods: The participants were 11 students who had participated in self-dieting program in a health center. Data were collected with in-depth interviews and analyzed by grounded theory in Strauss and Corbin (1990). Results: Through analyzing process, 36 concepts, 18 subcategories, and nine categories were deduced. In axial coding, casual condition, 'shrinking themselves' and 'oriented to selfish lifestyle', context condition, 'distress in mutual understanding' impacted on phenomenon, 'making health with autonomous living pattern'. Intervening conditions were 'practicing with active measures' and 'growing the willpower' and action-interaction condition, 'devoting realistic plan with positiveness' totally lead to consequence in 'regaining social relationship' and 'pursuing harmonious sound of mind and body'. The periods of process were divided four stages, reflecting self-characteristics, situational copping phase, applying period realistic strategies, and developing phase of social relationship. The core category, 'developing communication competency' incorporated the relationship between and among all categories and explained the process. Conclusion: The findings indicate that self leading health program helped to develop the communication competency. Therefore, we would consider about internalized motives and external incentives in health programs.

• Journal of Korean Library and Information Science Society
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• v.44 no.1
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• pp.177-199
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• 2013

Using a qualitative multimethod approach, this study was to construct a substantive theory about occupational socialization of librarians. Through theoretical sampling, 42 participants were in-depthly interviewed at three studies, i. e., phenomenological, ethnographic, and grounded theory approach. These data were analyzed and finally integrated using grounded theory approach. 'Acquiring Social Recognition as Information Professionals' was emerged the core category for describing and guiding the occupational socialization process. Six patterns were discovered: 'the Beliefs', 'the Seeking-Success', 'the Work-Obiligations', 'The Stucked', 'the Self-Pride', 'The Frustrated' Also, it discussed characteristics and socialization strategies of the pattern.

• Journal of Digital Convergence
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• v.13 no.11
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• pp.383-390
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• 2015

In this study it placed the object of the present invention is to provide a more efficient user interface experience to analyze the structure information and the user experience when using the pattern of the search with the number of intended use of the smart phone. Naver and Daum were the results of the study will consist of 28 dogs and 15 each category Naver and Daum had both a top-down sequential structure. In the case of Naver it has raised the possibility of cognitive load through the use of duplicate content and excessive scrolling news Daum has been in the case of shopping categories at the bottom of this error was raised the possibility of using touch gestures.

• Phonetics and Speech Sciences
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• v.1 no.4
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• pp.85-94
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• 2009

This paper investigates the intonation patterns of Korean spontaneous speech through an analysis of four dialogues in the domain of travel planning. The speech corpus, which is a subset of spontaneous speech database recorded and distributed by ETRI, is labeled in APs and IPs based on K-ToBI system using Momel, an intonation stylization algorithm. It was found that unlike in English, a significant number of APs and IPs include hesitation lengthening, which is known to be a disfluency phenomenon due to speech planning. This paper also claims that the hesitation lengthening is different from the IP-final lengthening and that it should be categorized as a new category, as it greatly affects the intonation patterns of the language. Except for the fact that 19.09% of APs show hesitation lengthening, the spontaneous speech shows the same AP patterns as in read speech with higher frequency of falling patterns such as LHL in comparison with read speech which show more LH and LHLH patterns. The IP boundary tones of spontaneous speech, showing the same five patterns such as L%, HL%, LHL%, H%, LH% as in read speech, show higher frequency of rising patterns (H% and LH%) and contour tones (HL%, LH%, LHL%) while read speech on the contrary shows higher frequency of falling patterns and simple tones at the end of IPs.

• Korean Journal of Health Education and Promotion
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• v.21 no.1
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• pp.1-23
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• 2004

The purpose of this study is to examine the effects of job-related characteristics on alcohol consumption among female workers. The Data was collected from a sample of 1,000 female workers by a stratified proportional quota sampling method derived from those who were working in Seoul. Drinking behavior pattern includes total amount of pure alcohol consumed during the last month (AC) measured by graduated quantity-frequency. Job-related characteristics (JRC) were measured by job-related stress, work characteristics, and organizational structure including length of working hours, number of times dining out together with workers per year, number of staff to supervise, employment status, occupational category, and proportion of female workers to male counterpart. Confounding variables include sociodemogrphic and socio-cultural attitudes toward alcohol expectancy, subjective norm of drinking, and gender-role attitude. Hierarchical multiple regression models show that the variability of AC was accounted for by some JRC including number of times dining together and employment status, with confounding variables held constant. However, the relationship between AC and JRC varied across occupational categories. Some implications were discussed in terms of health policy for female workers and further study for female drinking behavior.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.562-566
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• 2009

In this paper, we present a novel system to categorize web image search results using emotional concepts and to browse the results more conveniently and easily. The proposed system can categorize search results into 8 emotional categories based on emotion vector, which obtained by color and pattern features. Here, we use Kobayashi’s emotional categories: {romantic, natural, casual, elegant, chic, classic, dandy and modern}. With search results for a given query, the proposed system can provide categorized images for each emotional category. With 1,000 Yahoo! search images, we compared the proposed method with Yahoo! image search engine in respect of satisfaction, efficiency, convenience and relevance with a user study. Our experimental results show the effectiveness of the proposed method.

• Journal of Korean Medical classics
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• v.30 no.4
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• pp.83-93
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• 2017

Objective : Doctors' discussions on Makwon's warm-disease are studied in an effort to contemplate a way to use the outcome in practice. Method : Doctors' discussions on Makwon as found in researches and texts are categorized into physical and pathologica, and their symptoms and treatments are analyzed. Result & Conclusion : Many doctors of warm disease explained that, in terms of the physical aspect, Makwon is closely related to stomach. Some doctors also mentioned its relationship with triple engizers, defense and nutrient qi, and spleen. In terms of pathology, most of the doctors considered Makwon to be a hiding place of foul turbidity pathogen, and explained that a treatment has to be applied before the disease pattern worsens. Diverse syndroms of Makwonwere introduced. Their discussions mainly revolved around warm and epidemic or category of dampness-heat diseases. Alternating chills and fever was also mentioned often, and generalized pain, nausea, tongue of thick and slimy fur symptoms are shown. Ouguk's Dalwonneum is used as the basic treatment. The most effective prevention method of the incubation of pathogen are the symptoms that allows the analysis of the mechanism of disease. Therefore, a good utilization method of resolve turbidity with aroma or spices may contribute to the prevention of Makwon-disease in terms of cultural aspect.

• Fashion & Textile Research Journal
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• v.11 no.4
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• pp.515-526
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• 2009

From traditional ceremony to science technology, origami was used as technique for artistic creativity and functionality based on formative characteristics. The purpose of this study is to analyze the expressive characteristics of functionality in fashion design using origami technique. The method of this study was to analyze recent documentaries, fashion books, fashion magazines, internet web site and so forth. The results were as follows: In various fields of design, the category of the expressive characteristics was classified as efficient correspondence of space, compositive convergence of function, variable potentiality of form and human ergonomic optimum. In recent origami fashion based on functionality, the efficient correspondence of space was expressed constructive or decorative pocket design, using on clothing surface and varied design by lifestyle. The compositive convergence of function was expressed innovative connection of fashion items or non-fashion items and deconstructed classical clothing pattern. The variable potentiality of form was expressed control of form by irregular fold, dynamic metamorphosis by organic fold and creation of varied clothing silhouette. The human ergonomic optimum was expressed metamorphosis mechanism from two dimension to three dimension, suitable construction to physical ability and limit and organic form based on articular folding. The functional origami fashion means reflection of nomadic lifestyle, maximum of usability, pursuit of playful sensibility, creation of new body aesthetic and pursuit of technology and humanism. And the result of these study may be used for creative inspiration in fashion design because of unique characteristics.

• Journal of Nutrition and Health
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• v.26 no.2
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• pp.182-188
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• 1993

This study was accomplished to investigate the prevalence of obesity and the factors related to obesity of high school girls in the large cities from May 20 to July 10 1990. In this study, three hundred eighty nine high school girls were chosen from high schools located in Seoul and Inchon. Anthropometry including weight, height, and skinfold thickness (triceps) were measured, and dietary intakes were calculated according to food composition tables. Means of the obesity index, food pattern, nutrients intakes were compared by Pearson's correlation coefficient. Nutrient intakes of the groups categorized by tricep skinfold thickness were compared by means of Duncan's multiple range test. Prevalence of obesity was 16.7%, 3.6%, and 20.8% by criteria of skinflod thickness, BMI, and Rohrer Index, respectively. Most of the subjects had three meals and took snacks two times per day 23.9% of the subjects were taking nutrient supplements of which vitamin supplement was the most popular. Food habit of subjects such as frequency of snack and bedtime meal were positively related to fatness. Nutrient intakes of the obese groups classified by tricep skinfold thickness, tended to consume more calories than another tricep category groups. Therefore, it could be concluded that prevalence of obesity in this subject was higher than the one for the past years, and it was more profound in girls who had a poor food habits and high calorie intakes. Thus, these results suggested that a good food habits and adequate nutrient intakes are essential to prevent the obesity of high school girls.