• 한국임상수의학회지
• /
• 제37권2호
• /
• pp.75-81
• /
• 2020

The objective of the present study was to evaluate the effectiveness of autoligation techniques for castrating healthy male small breed dogs. Forty dogs were divided into four groups, with 10 in each group, based on maturity and the surgical technique used: 1) immature dogs aged less than 1 year, with autoligation of the spermatic cord via a scrotal approach (SAL) as the surgical technique (SAL-IM); 2) mature dogs aged 1 year or older, with the same SAL surgical technique (SAL-M); 3) immature dogs aged less than 1 year, with double ligation of the spermatic cord with an absorbable suture via a prescrotal approach (PDL) as the surgical technique (PDL-IM); and 4) mature dogs aged 1 year or older, with the same PDL surgical technique (PDL-M). The effectiveness of the surgical technique was evaluated by comparing the operating time and complications between these four groups. The significant decreases in operating times were found in SAL-IM and SAL-M compared with those of PDL-IM and PDL-M (p < 0.01 and p < 0.01). Regardless of maturity, the SAL surgical technique reduced operating time by approximately 69.5% compared with the PDL surgical technique. When the complication severities were scored, the results showed no significant differences among the four group. The autoligation technique for castration in healthy male small breed dogs is considered to be effective because the operating time consuming is less than conventional techniques.

• Genomics & Informatics
• /
• 제16권3호
• /
• pp.71-74
• /
• 2018

Because castration-resistant prostate cancer (CRPC) does not respond to androgen deprivation therapy and has a very poor prognosis, it is critical to identify a prognostic indicator for predicting high-risk patients who will develop CRPC. Here, we report a dataset of whole genomes from four pairs of primary prostate cancer (PC) and CRPC samples. The analysis of the paired PC and CRPC samples in the whole-genome data showed that the average number of somatic mutations per patients was 7,927 in CRPC tissues compared with primary PC tissues (range, 1,691 to 21,705). Our whole-genome sequencing data of primary PC and CRPC may be useful for understanding the genomic changes and molecular mechanisms that occur during the progression from PC to CRPC.

• Anatomy and Cell Biology
• /
• 제57권1호
• /
• pp.61-69
• /
• 2024

Hypogonadism is associated with an increased risk of coronary artery disease. This study sought to describe the histomorphology of the left coronary arteries of the adult male rabbit following orchiectomy and subsequent testosterone administration. We included 20 adult male rabbits, divided into a baseline group (n=2), an interventional group subjected to castration only (n=6), an intervention group subjected to castration followed by testosterone injection (n=6), and a control group (n=6). Key variables under investigation were serum testosterone levels, the intima-media thickness of coronary arteries, smooth muscle cell density, and adventitial collagen fiber density. The mean coronary arteries' intimal medial thickness was significantly higher in the castrated group than in controls (0.488 mm and 0.388 mm, respectively), while the testosterone-injected group had a mean of 0.440 mm. Mean smooth muscle cell density was significantly lower in the castrated rabbits vs. controls (26.96% and 47.80%, respectively), this observation being reversed with testosterone injection (47.53%). Mean adventitial collagen fiber density was significantly higher in the castrated group than in controls (66.6% and 36.1%, respectively), with a marginal difference after testosterone injection (65.2%). This study demonstrates that castrationinduced hypogonadism causes morphological changes in the coronary arteries that are partly reversible using testosterone injections. These findings provide a morphological basis for understanding the role of testosterone in coronary arteries.

• 한국축산식품학회지
• /
• 제30권3호
• /
• pp.419-426
• /
• 2010

재래흑염소를 각 처리구별로 8두씩 배치하여 총 32두(4처리$\times$8두)를 대상으로 대조구(생후 5개월령의 비거세구)와 3개 처리구(T1구: 7개월령 거세구, T2구: 5개월령 거세구, T3구: 3개월령 거세구)로 구분 배치하여 총 410일간 시험한 결과는 다음과 같다. 비육 전기간(410일간) 동안의 총 증체량은 T2구(28.4 kg)으로 가장 높았으며, 일당증체량에서도 비슷한 경향을 보였다. 총 사료섭취량는 T3구가 410.82 kg으로 가장 낮았고, 사료요구율은 T2가 16.39로 사료효율성이 가장 좋게 나타났다. 흑염소 육의 가열감량과 드롭로스는 대조구가 각각 35.53%와 2.08로 가장 높았고(p<0.05), 총 콜레스테롤함량은 시험구가 대조 구 보다 더 높았다(p<0.05). 또한 관능검사의 다즙성, 연도, 향미, 조직감, 염소 특이취 및 종합평가에서도 전반적으로 처리구가 대조구보다 낮아 더 좋은 관능검사 결과를 보였으며(p<0.05), 그 중에서도 T2구(3.61점)가 가장 좋았다(p<0.05). 육색에서 명도(L)값과 Hue값은 대조구가 가장 낮았고, 적색도(a)값은 T3구, 황색도(b)와 Chroma는 T2구가 가장 높게 나타났다. 지방산 조성에서 oleic acid은 T2구가 53.76%으로 나타났고, 단일불포화지방산 함량(MUFA)은 T1구와 T2구가 가장 높았다(p<0.05). 따라서 MUFA/SFA의 비율은 T1구와 T2구가 대조구보다 더 높았다(p<0.05). 이상의 결과를 종합해볼 때, 고품질 흑염소육 생산을 위해서는 생후 5개월령의 거세가 생산성과 육질개선에서 가장 유리할 것으로 판단된다.

• 한국임상수의학회지
• /
• 제15권2호
• /
• pp.303-306
• /
• 1998

The three cases of cryptorchid are reported here in order to demonstrate the different surgical techniques that were carried out to remove crytochid testes in dogs and to introduce clinical cases on crytorchidism. Three dogs were presented in the clinic of Ecole Veterinaire de Lyon in May, 1998 with two in the left-sided unilateral abdominal cryptorchid and with one in bilateral inguinal mobile cryptorchid. There were two poodle at the age of more than 4 years old and 8 years old respectively with one boxer at 4 years old. In two abdominal cryptotchids, the skin was incised in caudal paramedian approach. Then, the linea alba were incised and cryptorchidectomy was peformed accompaning one with castration and the other with vasectomy by the request of the owners. In inguinal testicles, prescrotal skin incision was made to remove both testicles. The surgical outcome was good without any Their behaviors became agreeable as the proprietors reported. In the dog with vasectomy, the behavior changes were not noticeable.

• 한국임상수의학회:학술대회논문집
• /
• 한국임상수의학회 2008년도 춘계학술대회
• /
• pp.131-131
• /
• 2008

• 한국환경성돌연변이발암원학회:학술대회논문집
• /
• 한국환경성돌연변이발암원학회 2002년도 Current Trends in Toxicological Sciences
• /
• pp.101-102
• /
• 2002

• Asian-Australasian Journal of Animal Sciences
• /
• 제29권5호
• /
• pp.709-715
• /
• 2016

The objective of the research was to determine the chemical composition as well as the physicochemical properties of the longissimus muscle from Korean entire and castrate elk. Twelve elk stags were raised and fed on concentrate with ad libitum hay. All animals were equally divided into castrated and non-castrated (entire) males, and slaughtered at 5 year of age. It was found that entire elk, in comparison with castrate elk, had higher content of moisture and lower content of fat (p<0.05). Compared with entire males, the castrates had lower pH and shear force values (p<0.05). However, castrates had higher $L^*$, $a^*$, and $b^*$ values compared with entires (p<0.05). An analysis of the fatty acid profile revealed that the muscles of entire and castrate elk had the most abundant concentrations of the following fatty acids: palmitic acid (C16:0) of the saturated fatty acid, and oleic acid (C18:1n-9) of the unsaturated fatty acid. The entire elk contains higher proportions of linoleic acid (C18:3n6), eicosenoic acid (C20:1n9), and arachidonic acid (C20:4n6) (p<0.05). Cholesterol content in elk was not affected by castration. The predominant free amino acid was glutamic acid related to umami taste. It is apparent that the castrate animals carried higher content of histidine, isoleucine, and leucine than those of the entire group (p<0.05). In this study, it was concluded that venison quality of elk is affected by castration and these results can provide fundamental information for venison production.

• Asian-Australasian Journal of Animal Sciences
• /
• 제8권6호
• /
• pp.617-625
• /
• 1995

Distribution of wholesale carcass cuts and tissues was studied in Omani Dhofari bulls and steers raised under intensive management and slaughtered over a range of 110 to 210 kg body weight. The fore quarter of Dhofari cattle carcasses was heavier than the hind quarter with the chuck being the heaviest cut in the half carcass followed by the round whereas the flank was the lightest cut. Proportions of the fore quarter and its cuts increased whereas that of the hind quarter and its cuts decreased with increasing carcass weight. The fore quarter contained higher proportions of carcass tissues especially intermuscular fat than the hind quarter. The chuck and round contained the highest proportions of lean and bone and the flank the least. There was a general trend of increasing proportions of fat and decreasing proportions of lean and bone in carcass cuts and fore and hind quarters with increasing slaughter weight and age. As % total body fat (TBF), total carcass fat (TCF) increased whereas total non-carcass fat (TNCF) decreased. The largest proportion of TBF was deposited in the intermuscular site. Among the TNCF depots, the kidney and omental contributed the highest proportions whereas the pelvic and channel were the lowest. Proportions of M. rhomboideus and M. splenius increased in the half carcass whereas that of M. semitendinosus decreased as the cattle increased in size. The axial skeleton contributed 47.4-51.1, the fore limb 21.6-22.6 and the hind limb 23.9-26.2% of the total carcass bone. Proportions of axial skeleton increased whereas that of fore and hind limbs decreased with increasing slaughter weight and age. There were no major effects of castration on the distribution of weight of carcass cuts or carcass tissues. Steers had higher total body fat at 160 kg body weight and higher proportions of mesenteric, scrotal, pelvic, kidney and total non-carcass fat at 210 kg weight than bulls. As % of total body fat, steers fad significantly higher kidney and total non-carcass fat. There was little effects of castration on proportions of dimensions of individual muscles or bones.

• Journal of Animal Science and Technology
• /
• 제52권1호
• /
• pp.37-42
• /
• 2010

본 시험은 거세시기가 흑염소의 발육, 육질 및 지방산 조성에 미치는 효과를 구명하기위하여 흑염소 육성축 수컷 45두를 공시하여 거세시기를 각각 달리하여 2008년 3월 21일부터 2008년 10월 31일까지 225일간 실시하였으며 그 결과는 다음과 같다. 일당증체량은 거세시기별로 차이는 없었으나 3개월령과 5개월령에 거세한 것이 다소 높은 경향이었고, 비거세가 거세보다 높은 것으로 나타났다(P<0.05). 도체율은 15일령 거세가 7개월령 거세보다 높았고(P<0.05), 정육율은 거세시기별로 차이가 없었으나 비거세가 거세보다 높았다(P<0.05). 지방율은 거세시기가 빠를수록 높았고 거세가 비거세보다 높았다(P<0.05). 흑염소고기의 일반조성분인 수분함량은 거세시기가 빠를수록 감소하는 경향이었고, 조단백질과 조지방 함량은 거세시기가 빠를수록 증가하는 경향이었다. 육질의 물리적 특성인 전단력, 가열감량 그리고 보수력은 거세시기별로 차이가 없었으며 관능검사 결과 다즙성과 연도는 5개월령 거세가 다소 우수한 경향이었고, 향미는 7개월령 거세가 15일령과 3개월령 거세보다 우수하였다(P<0.05). 포화지방산 함량은 5개월령 거세가 높았고 3개월령 거세가 낮았다(P<0.05). 불포화지방산 함량은 반대로 3개월령 거세가 가장 높았고 5개월령 거세가 낮았으며(P<0.05) 거세와 비거세간에는 차이가 없었다. 단가불포화지방산 함량은 거세기기별로 차이가 없었으나 3개월령 거세가 비거세보다 높았다(P<0.05). 이러한 결과를 종합적으로 고려하면 흑염소의 발육과 육질 개선에 유리한 거세시기는 3~5개월령이 적정할 것으로 사료된다.