• 문화기술의 융합
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• 제9권2호
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• pp.545-551
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• 2023

오늘날 누구나 디지털 정보를 용이하게 활용할 수 있게 됨에 따라 디지털 증거의 채택이 증가되고 있다. 하지만 다양한 음성 파일 편집 도구를 보급과 함께 정교한 편집 과정을 거친 음성 녹음 파일의 경우 위변조 진위 여부를 판단하는 것은 사실상 불가능하다. 본 연구는 음성 녹음 파일에 삽입, 삭제, 연결 및 합성 편집 기술을 활용해 원본 파일과 구별하기 어려운 위변조가 가능함을 증명하고자 한다. 본 연구는 위변조 된 음성 파일을 원본과 동일한 확장자로 인코딩하는 작업을 통해 위변조 검출의 어려움을 제시한다. 또한 특징점이 발생한 실험에 한 하여 추가적으로 천이대역의 삭제 및 2차 인코딩 작업을 수행할 경우 위변조 검출은 불가능함을 나타냈다. 이를 통해 본 연구는 음성 녹음 파일을 디지털 증거로 채택하기 위한 더 엄격한 증거능력 판단 기준 수립에 공헌할 것으로 기대된다.

• 동의생리병리학회지
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• 제18권4호
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• pp.1192-1198
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• 2004

Sasang Constitutional Medicine is a major branch of Korean Traditional Medicine. The differences of disease susceptibility to be shown in Sasang constitution may be due to genetic factors. Therefore, I examined interrelationship among cerebral infarction (CI), apolipoprotein E (apo E) gene polymorphism, and Sasang constitutional classification. Apo E is a key protein modulating the highly atherogenic apoB containing lipoproteins and is a candidate gene for the development of coronary artery disease (CAD). The ε2 and/or ε4 alleles were the first to be implicated in premature CAD, which resulted in this polymorphism being extensively studied. I investigated the association between apo E genotype and CI by case-control study in a Korean population. I also classified CI patients and control group into groups according to Sasang Constitutional Medicine. 218 CI patients and 379 controls without CI were examined. Apo E genotype was determined by 8% polyacrylamide gel separation after DNA amplification. A frequency of apo E ε3/ε3 in the apo E genotype distribution was higher in the CI patients compared with that in controls. Also, it was widely known that Taeumin was easily attacked with CI, but there was no association between apo E polymorphim and Taeumin. However, the Taeumin constitution did not enhance the relative risk for CI in the subjects with apo E ε2 and/or ε4 alleles. No differences in the apo E genotypes frequencies were observed in the Taeumin compared with that in the other constitutions. In addition, I investigated whether the DD(deletion/deletion) or ID(insertion/deletion) genotype of angiotensin converting enzyme (ACE) gene, a candidate gene for CI, was associated with CI, Taeumin constitution, and apo E polymorphism. As a result, the frequency of Taeumin constitution was significantly higher in CI patients with both apo E ε3/ε4 and ACE ID/DD genotypes than in the remaining Sasang constitutions. In summary, it was concluded that the apo E polymorphism is a major risk factor for CI in Koreans and the ACE ID/DD genotype enhanced the relative risk for CI in the subjects with apo E ε3/ε4 genotype and Taeumin constitution.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5249-5252
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• 2014

Nogo protein, encoded by gene reticulon-4 (RTN4), includes three major isoforms by different splicing, named Nogo-A Nogo-B and Nogo-C. Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The CAA insertion/deletion polymorphism (rs34917480) within RTN4 3'-UTR has been reported to be associated with many cancer types. In order to investigate the relationship between this polymorphism and susceptibility to non-small cell lung cancer (NSCLC) in the Chinese population, we conducted the present case-control study including 411 NSCLC patients and 471 unrelated healthy controls. The genotype distributions were significantly different between cases and controls (p=0.014). We found that the del allele could significantly increase NSCLC risk (ins/ins vs ins/del: p=0.007, OR 1.46, 95%CI=1.11-1.93; dominant model: p=0.004, OR 1.47, 95%CI=1.13-1.92 and allele model: p=0.008, OR 1.35, 95%CI=1.08-1.67). This association was stronger in participants over 60 years old, males and smokers. We therefore conclude that the CAA insertion/deletion polymorphism (rs34917480) contributes to non-small cell lung cancer risk in Chinese population. Age, sex and environmental exposure are also related to carcinogenic effects of rs34917480.

• 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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• 한국정보과학회언어공학연구회 1997년도 제9회 한글 및 한국어 정보처리 학술대회
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• pp.160-166
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• 1997

본고는 우리말에서 빈번하게 일어나는 축약 및 생략 현상을 언어학적으로 규명하기 위한 노력의 일환으로,. 이를 위해 실제 대화체에서 나타나는 격조사 생략현상에 대한 관찰결과를 기술적으로 분석하고, 이를 토대로 향후 대화체 이해 시스템 구현을 위한 생략된 격조사 복원연구의 방향을 제시한다. 연구를 위해 녹취한 약 한시간 분량의 2인 흑은 3인의 자연스런 라디오 대담 프로그램 전화대화들을 전사한 자료를 중심으로, 실제 대화에서 실현되거나 생략된 격조사들을 유형별로 분석한 격과를 보고하고, 기존의 연구 및 관찰에 경험적 타당성을 제공함과 동시에 그들의 분석을 대화이해 시스템에 구현하고자 할 때 발생할 수 있는 문제점을 지적한다. 나아가 격조사가 생략된 명사구들이 나타나는 환경을 통사 및 담화적 특성에 따라 분류함으로써, 대화이해 시스템 구현을 목적으로 하는 격조사 생략현상 연구 및 이를 토대로 한 명사구와 용언 사이의 문법적 의미적 관계 규명을 위한 향후 연구에서 어휘 부의 확장 필요성을 논한다.

• 한국식품영양과학회지
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• 제23권6호
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• pp.916-921
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• 1994

The inhibitory effects of the juice and boiling water extract of Houttuyina cordata Thunb., which has been known as a traditional folk antitumor agent, on the genotxicity induced by mutagens were investigated . For this purpose, Salmonella typhimurium TA98 and TA100, and the transheterozygous (mwh/+) third larvae of Drosophila melanogaster were used. The juice of fresh H. cordata 9JHC) and boiling H. cordata extract (BHC) showed antimutagenicities toared alfatoxin B₁ in S. typhimurium TA 98 and TA100. The JHC's inhibitory effect increased by 76% to 98% as the adding concentrations increased, and the BHC had a 86-97% inhibitory effect. however, in the case of N-methyl-N'-nitro-N nitrosoguanidine (MNNG), the JHC's inhibitory effect was 52-60% irrespectively of its concentrations and the BHC had a low inhibitory effect. The JHC and BHC slightly reduced the somatic chromosomal mutagenicity by MNNG in the wing hair spot test system (mwh/+) of D. melanogaster, which suggests that they can inhibit gene mutation , deletion and mitotic chromosomal recomgination.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1991년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 22-24 Oct. 1991
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• pp.793-798
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• 1991

Implementation of AGVS (Automated Guided Vehicle System) in CIMS (Computer Integrated Manufacturing System) generally requires substantial study to optimize design and performance of the guide path. Traditional mathematical approaches have been used with limited success to analyze AGVS. These approaches, however, do not provide a practical opportunity to use by path designers. This paper presents a new approach based on Jules in designing and assessing AGV path to have better design of the closed-loop layout. A framework for the approach is proposed and a case study is reported to demonstrate the framework. Deletion of seldom used paths and addition of bypasses to solve the congestion problem are conducted automatically through simulation expefiments. To visualize die results a graphic control program is developed and integrated with AutoMod/AutoGram simulation package.

• 한국영어학회지:영어학
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• 제2권4호
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• pp.471-494
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• 2002

May(1985) argued that the regress problem of antecedent-contained deletion (ACD) construction could be resolved easily by positing QR. But the proposal has some conceptual and empirical problems. To resolve the problems of QR account on ACD, Hornstein(1994) suggested a new approach viz. LF A-movement approach. In the Minimalist framework, an object raises to the [Spec, Agro] to check the accusative case. Through this movement, the regress problem can be resolved naturally without QR. But the LF A-movement account has the same conceptual problem as the QR approach. In addition to the conceptual problem, it has also empirical problems which were pointed out by Kennedy(1997). To solve the problems, I propose that the object raise to [Spec Agro] overtly as Koizumi(1993, 1995) and Lasnik(1995) insisted. In addition to the proposal, I adopt another assumption that only the copy of a quantifier could become a variable by the vehicle change, which was suggested by Brody(1995). With the above proposals, the unnatural QR operation could be dispensed with and the conceptual and empirical problems which were made concerning the LF A-movement approach could be resolved.

• Journal of the Korean Data and Information Science Society
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• 제16권2호
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• pp.429-444
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• 2005

The identification of unusual observations such as outliers and high leverage points has drawn a great deal of attention for many years. Most of these identifications techniques are based on case deletion that focuses more on the outliers than the high leverage points. But residuals together with leverage values may cause masking and swamping for which a good number of unusual observations remain undetected in the presence of multiple outliers and multiple high leverage points. In this paper we propose a new procedure to identify outliers and high leverage points simultaneously. We suggest an additive form of the residuals and the leverages that gives almost an equal focus on outliers and leverages. We analyzed several well-referred data set and discover few outliers and high leverage points that were undetected by the existing diagnostic techniques.

• 대한산업공학회지
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• 제18권1호
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• pp.121-139
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• 1992

AGVS(Automated Guided Vehicle Systems) in material handling have been used widely since late 1970s. Implementation of an AGVS generally requires substantial study to optimize the design and performance of guide-paths. Traditional mathematical approaches have been used with limited success to analyze AGVS. These approaches, however, do not provide a practical tool for guide-path designers. This paper presents a new approach based on rules in designing and assessing AGV guide-paths to improve the design of a closed-loop layout. A framework for the integrated approach is proposed, problem solving procedures are explained, and a case study is reported to demonstrate the framework. Deletion of seldom used guide-paths, and addition of bypasses to solve the congestion problem, are conducted interactively and iteratively through simulation experiments. To visualize the results, a graphic control program is developed and integrated with the AutoMod/AutoGram simulation package.

• Communications for Statistical Applications and Methods
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• 제30권6호
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• pp.605-629
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• 2023

This paper proposes some diagnostics procedures for the skew-t linear regression model with censored response. The skew-t distribution is an attractive family of asymmetrical heavy-tailed densities that includes the normal, skew-normal and student's-t distributions as special cases. Inspired by the power and wide applicability of the EM-type algorithm, local and global influence analysis, based on the conditional expectation of the complete-data log-likelihood function are developed, following Zhu and Lee's approach. For the local influence analysis, four specific perturbation schemes are discussed. Two real data sets, from education and economics, which are right and left censoring, respectively, are analyzed in order to illustrate the usefulness of the proposed methodology.