• Journal of Chest Surgery
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• 제27권9호
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• pp.732-737
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• 1994

From January 1983 to December 1992, There were 1441 papers in the Korean Journal of Thoracic and Cardiovascular Surgery. Among these papers, 783[54.3%] were original article or clinical analysis and 652[45.2%] were case reports. A total of 319 papers contained some statistical analysis. In 150 cases[47.0%] of these 319 papers, the statistical description was insufficient. Of the correctly described papers, 115[68%] had more than one statistical error. Of course, in many cases the errors were not considered to be severe, but they were often sufficient to raise doubts about some inferences. We suggest that authors should be more careful when they describe and apply statistical methods. If possible, authors should interpret results with statistical specialists. And we also suggest that our society have more extensive statistical refereeing system. This would at least prevent the worst errors from appearing in print. The last suggestion is elementary instruction in statistical methods during preclinical training.

• Journal of Chest Surgery
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• 제51권6호
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• pp.410-414
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• 2018

Primary pulmonary meningioma is a rare disease, and chordoid meningioma is an uncommon variant of meningioma in the central nervous system (CNS) with a high recurrence rate. We report a case of primary pulmonary chordoid meningioma that presented as a solitary pulmonary nodule (SPN). The SPN was resected by thoracoscopic wedge resection and was revealed to have characteristics of chordoid meningioma. After confirming the absence of a meningioma in the CNS by brain imaging, the nodule was diagnosed as a primary pulmonary chordoid meningioma. The patient remained disease-free after 26 months postoperatively. To our knowledge, this is the third case of primary pulmonary chordoid meningioma to be reported.

• Journal of Chest Surgery
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• 제54권6호
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• pp.513-516
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• 2021

An 87-year-old man presented with a saccular aneurysm at the proximal descending thoracic aorta. As computed tomography revealed a shaggy aorta, we planned hybrid thoracic endovascular aortic repair (TEVAR) with embolic protection devices (EPDs) in both internal carotid arteries to prevent a cerebrovascular accident. We inserted an Emboshield NAV⁶ Embolic Protection System (Abbott Vascular, Abbott Park, IL, USA) into both internal carotid arteries before performing the TEVAR procedure. The patient was discharged from the hospital on postoperative day 4 without any neurological complications.

• Journal of Chest Surgery
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• 제40권7호
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• pp.512-516
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• 2007

기계적인 순환보조장치는 급성호흡부전이나 심부전에서 생명을 구할 수 있는 방편의 하나이다. 현재 여러 가지 형태의 순환 보조장치가 있으며 Twin-Pulse Life Support (T-PLS) system은 박동형 펌퍼의 한 종류다. 3예의 심한 심폐기능부전 상태 환자에게 순환보조장치로 T-PLS system을 사용하였다. 적응증은 인공호흡기와 강심제를 최대한 사용함에도 불구하고 지속되는 호흡부전이나 심부전이었다. 감염에 의한 호흡부전환자가 2예, 심근염에 의한 심부전 환자가 1예였다. 각각 한 명의 호흡부전환자와 신부전 환자가 생존하였는데 보조장치의 사용시간은 각각 3일과 5일이었다. T-PLS system은 순환보조장치로 유용하게 사용할 수 있으며 다발성 장기부전이 오기 전에 적용하여야 할 것으로 생각된다.

• Journal of Chest Surgery
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• 제41권5호
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• pp.659-662
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• 2008

흉강경을 이용한 폐절제술이 1990년대 초반 처음으로 소개된 이후로 조기 폐암 환자의 수술에 있어 안정성과 적합성이 발표되면서 그 시행 횟수가 서서히 증가되고 있다. 그러나, 흉강경을 이용한 수술은 2차원 영상과 불안정한 카메라의 움직임, 기구의 움직임이 제한되는 등의 여러 가지 단점들이 있다. 이러한 단점을 극복하고 최근에 개발된 다빈치 로봇 시스템은 고해상도의 3차원 입체영상과 사람의 팔목관절과 유사한 움직임을 구사하는 기구들로 인하여 더욱 안정되고 편리하게 수술을 시행할 수 있게 하였다. 본원에서는 다빈치 로봇 시스템을 이용하여 3명의 조기 폐암환자에서 폐엽 절제술을 시행하였기에 보고하는 바이다.

• The Korean Journal of Physiology and Pharmacology
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• 제23권5호
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• pp.305-310
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• 2019

The physiomic approach is now widely used in the diagnosis of cardiovascular diseases. There are two possible methods for cardiovascular physiome: the traditional mathematical model and the machine learning (ML) algorithm. ML is used in almost every area of society for various tasks formerly performed by humans. Specifically, various ML techniques in cardiovascular medicine are being developed and improved at unprecedented speed. The benefits of using ML for various tasks is that the inner working mechanism of the system does not need to be known, which can prove convenient in situations where determining the inner workings of the system can be difficult. The computation speed is also often higher than that of the traditional mathematical models. The limitations with ML are that it inherently leads to an approximation, and special care must be taken in cases where a high accuracy is required. Traditional mathematical models are, however, constructed based on underlying laws either proven or assumed. The results from the mathematical models are accurate as long as the model is. Combining the advantages of both the mathematical models and ML would increase both the accuracy and efficiency of the simulation for many problems. In this review, examples of cardiovascular physiome where approaches of mathematical modeling and ML can be combined are introduced.

• Journal of Chest Surgery
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• 제43권4호
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• pp.428-432
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• 2010

67세 남자환자가 6개월 전부터 반복되는 배부 동통을 주소로 내원하였다. 환자는 11년 전 Stanford B형 대동맥 박리로 하행 대동맥 스텐트 도관 삽입술을 시행 받았다. 대동맥 컴퓨터 단층촬영에서 좌 쇄골하동맥 기시부에서 시작되어 복부 대동맥 분지 부위까지 진행된 대동맥 박리, 스텐트 도관 근위부의 제 1형 endoleak 및 하행 대동맥의 낭종성 확장을 관찰하였다. 체외 심폐 순환 하에 무명동맥, 좌 총경동맥, 좌 쇄골하동맥의 탈분지 및 재혈관화술을 시행하고, 수술 후 13일째 대동맥 궁에서 하행대동맥까지 스텐트 도관을 삽입하는 Hybrid 술식을 성공적으로 시행하였고, 수술 후 시행한 대동맥 컴퓨터 단층촬영에서 제 1형 endoleak의 완전한 소실을 보였으며 퇴원 후 8개월간 특이 합병증 없이 경과 관찰 중이다.

• Journal of Chest Surgery
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• 제26권4호
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• pp.255-259
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• 1993

The efficacy of the autotransfusion system is a reducing the need of intraoperative and postoperative transfusion in cardiovascular surgery. Between January 1990 and December 1991, we experienced 23 cases of autotransfusion using Haemonetic Cell Saver in cardiovascular surgery [Experimental group]. Another 13 cases which were taken similiar operations without Cell Saver during same period [Control group]. The amounts of blood transfused are 4.23 1.84 units in Control group, 2.82 1.84 units in Experimental group. Postoperatively, both groups showed decreased platelet counts, mild prolongation of prothrombin and partial thromboplastin time compred to preoperative value [P<0.001], but there were no significant differences between two group [P=NS]. Plasma hemoglobin was markedly increased in Experimental group compared with Control group [p<0.05]. In Experimental group, amount of average processed blood by Cell Saver was 700ml of which composition was hemoglobin 17mg/dl, hematocrit 50.0%, RBC 5,590,000/ml, WBC 7500/ml, and platelet 40,000/ml. The culture of the processed blood revealed no growth of the organisms. Conclusively, Cell Saver autotransfusion system is a simple, safe, and cost effective method especially in the cases associated with massive bleeding. However, it requires familiarity with system, gentle manipulation of suction tip, and careful selection of candidates to obtain maximal benefits .

• 생약학회지
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• 제15권4호
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• pp.188-193
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• 1984

It was previously indicated that 'Samulanshintang' had been examined for effects of the anticonvulsive, antipyretic, analgesic, sedative and antispasmodic actions. In order to investigate the effect on the cardiovascular system and anemic rabbits induced by phenlhydrazine HCl, pharmacological studies have been carried out with extract. The results of this investigation were summarized as follows: The relaxation of bronchial smooth muscle and antihistamine action were recognized. Antihypertensive and vasodilating actions due to vascular smooth muscle relaxation were noted in frogs and rabbits. 'Samulanshintang' lowered the rate of anemia induced by phenylhydrazine and rapidly recovered from the anemia state.

• 대한임상독성학회지
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• 제14권2호
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• pp.100-106
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• 2016

Purpose: Beta blocker (BB) has been prescribed for anxiety and panic disorder. Patients intoxicated by psychiatric drugs have often been exposed to BB. Moreover, BB overdose has adverse effects including cardiovascular effects, which can be life-threatening. This study was conducted to identify the characteristics of BB intoxication with psychiatric drugs and the adverse effects on the cardiovascular system. Methods: A single center, retrospective study was performed from January 2010 to December 2015. A total of 4,192 patients visited the emergency department (ED) with intoxication, and 69 with BB intoxication were enrolled. Results: Overall, 64 patients (92.8%) of enrolled patients were intoxicated with drugs prescribed for the purpose of psychiatric disorders. Propranolol was the most common BB (62 cases, 96.2%), and the median dose was 140.0 mg (25%-75% 80.0-260.0). Twenty-four patients (37.5%) had experienced cardiovascular events, and these patients tended to have decreased mentality, hypotension and coingestion with quetiapine. An initial mean arterial pressure (MAP) below 65 mmHg (odds ratio 10.069, 95% confidence interval 1.572-64.481, p=0.015) was identified as a factor of cardiovascular event upon multiple logistic regression analysis. Conclusion: Initial MAP below 65 mmHg was a factor of cardiovascular adverse effect in patients of BB intoxication with psychiatric drugs.