• Journal of Chest Surgery
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• 제44권3호
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• pp.208-214
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• 2011

Background: Periprocedural treatment with high-dose statins is known to have cardioprotective and pleiotropic effects, such as anti-thrombotic and anti-inflammatory actions. We aimed to assess the efficacy of high-dose rosuvastatin loading in patients with stable angina undergoing off-pump coronary artery bypass grafting (OPCAB). Materials and Methods: A total of 142 patients with stable angina who were scheduled to undergo surgical myocardial revascularization were randomized to receive either pre-treatment with 60-mg rosuvastatin (rosuvastatin group, n=71) or no pre-treatment (control group, n=71) before OPCAB. The primary endpoint was the 30-day incidence of major adverse cardiac events (MACEs). The secondary endpoint was the change in the degree of myocardial ischemia as evaluated with creatine kinase-myocardial band (CK-MB) and troponin T (TnT). Results: There were no significant intergroup differences in preoperative risk factors or operative strategy. MACEs within 30 days after OPCAB occurred in one patient (1.4%) in the rosuvastatin group and four patients (5.6%) in the control group, respectively (p=0.37). Preoperative CK-MB and TnT were not different between the groups. After OPCAB, the mean maximum CK-MB was significantly higher in the control group (rosuvastatin group $10.7{\pm}9.75$ ng/mL, control group $14.6{\pm}12.9$ ng/mL, p=0.04). Furthermore, the mean levels of maximum TnT were significantly higher in the control group (rosuvastatin group $0.18{\pm}0.16$ ng/mL, control group $0.39{\pm}0.70$ ng/mL, p=0.02). Conclusion: Our findings suggest that high-dose rosuvastatin loading before OPCAB surgery did not result in a significant reduction of 30-day MACEs. However, high-dose rosuvastatin reduced myocardial ischemia after OPCAB.

• 대한의용생체공학회:의공학회지
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• 제29권5호
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• pp.400-407
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• 2008

A health index was proposed that evaluates personal health state from both measured physiological variables and survey questions. Four health indices were defined such as cardiovascular index, stress index, obesity index, and management index. The total health index was calculated by summing these four health indices. Physiological variables such as blood pressure, heart rate variability(HRV), accelerated photoplethysmograph(APG), and body fat percentage were non-invasively measured and a survey questionnaire that asks personal health state, exercise intensity, and food preference was developed. The suggested health index was applied to thirty eight persons including 30 patients and 8 normal persons with an average age of 51.8. The average health index was estimated to be 75.1 out of 100 points. Young age group(below 50) and men group showed higher health indices than the aged(over 50) and women groups. The correlation coefficient between the cardiovascular index and stress index was found to be 0.513, which means stress is related to cardiovascular health state. The correlation coefficient between the measurements and survey questions was 0.385 for the cardiovascular index. It was as low as 0.182 for the stress index. More case studies may improve correlations between measurements and survey questions, and then, the current health index system may develop as an effective tool to evaluate personal health state.

• 근관절건강학회지
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• 제30권3호
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• pp.254-262
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• 2023

Purpose: This study was to determine the effect of Individualized education-counseling program on the performance of Health behavior and Cardiovascular risk after discharge inpatients with percutaneous coronary intervention. Methods: This study is a quasi-experimental study of the non-equivalence control group and the subjects of this study were patients who underwent percutaneous coronary intervention for coronary artery disease and had no complications due to severe arrhythmia or heart failure. The purpose of the study was explained to the subjects who met the selection conditions, and written consent was obtained, and 50 randomized experimental groups and 50 control groups were selected and assigned. Results: Compared to the control group, health behaviors were significantly higher after 1 week (F=33.63, p<.001) and 12 weeks (F=23.63, p<.001). The cardiovascular risk score based on Framingham risk score differed significantly depending on the measurement period (F=26.18, p<.001), there was no significant difference in the interaction between the two groups and the measurement period (F=0.72, p=.469). Conclusion: It was confirmed that the Individualized education counseling program provided to patients with Percutaneous coronary intervention was effective in increasing the subject's health behavior, but not in lowering the cardiovascular risk.

• 수면정신생리
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• 제30권1호
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• pp.3-8
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• 2023

Periodic limb movement disorder (PLMD) is a sleep-related movement disorder characterized by involuntary, rhythmic limb movements during sleep. While PLMD itself is not considered life-threatening, its association with certain underlying health conditions raises concerns about mortality risks. PLMD has been found to be associated with cardiovascular diseases such as hypertension and cardiovascular disease. The fragmented sleep caused by the repetitive limb movements and associated arousals may contribute to sympathetic activation, chronic sleep disruption, sleep deprivation, and subsequent cardiovascular problems, which can increase mortality risks. The comorbidities and health factors commonly associated with PLMD, such as obesity, diabetes, and chronic kidney disease, may also contribute to increased mortality risks. PLMD is often observed alongside other neurological disorders, including restless legs syndrome (RLS) and Parkinson's disease. The presence of PLMD in these conditions may exacerbate the underlying health issues and potentially contribute to higher mortality rates. Further research is needed to elucidate the specific mechanisms linking PLMD to mortality risks and to develop targeted interventions that address these risks.

• 한국방사선학회논문지
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• 제8권3호
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• pp.117-121
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• 2014

심장의 모양 및 혈관에 관한 의료학적 지식습득은 의료인 및 의료기사들과 같은 의료전문인들에게는 필수적 요구사항이다. 심장의 모형을 통한 의료지식의 습득은 환자의 생명과도 직결되는 중요한 사항이기 때문에 보다 정확한 의료지식이 필요하다. 따라서 심장모양 및 심장혈관질환에 대한 다양한 의료교구재의 연구 및 개발이 필요하다. 이번 연구에서 만들어진 심장 및 심장혈관의 투시 모형장비를 사용하여 심장 혈류의 투시조영시의 볼 수 있는 방사선학적 사진 영상을 미리 습득할 수 있으며, 또한 투시 조영 중 환자의 자세의 따른 심장의 위치와 모형을 미리 예측해 볼 수도 있다. 결론적으로 우리가 고안한 심장혈관 투시 장비를 사용하여 심장혈관의 해부학적 지식을 미리 습득함으로서 면허 취득 후에 임상생활에 있어서의 심장혈류에 관한 정확한 이해에 도움을 줄 수 있을 것으로 사료된다.

• Journal of Chest Surgery
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• 제43권6호
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• pp.747-752
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• 2010

흉복부대동맥류 질환에서 고전적인 수술은 고위험군 환자에서 아직까지 높은 합병증 발생과 사망률을 나타낸다. 최근에는 스텐트 그라프트를 이용한 혈관내 시술(endovascular repair)이 시행되고 있으나 내장동맥의 보존이 시술의 걸림돌이 되고 있다. 저자들은 2명의 고위험군 흉복부대동맥류 환자에서 내장동맥 우회술과 흉복부대동맥에 스벤트 그라프트를 삽입하는 하이브리드 술식을 이용하여 성공적으로 치료하였다.

• Journal of Preventive Medicine and Public Health
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• 제37권2호
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• pp.120-126
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• 2004

Objectives : This study sought to examine relationships between alcohol drinking and cardiovascular disease mortality and all-cause mortality. Methods : From March 1985 through December 1999, 2,696 males and 3,595 females aged 55 or over as of 1985 were followed up for their mortality until 31 December 1999. We calculated the mortality risk ratios by level of alcohol consumption. Among the drinker, the level of alcohol consumption was calculated by the frequency of alcohol comsumption and the type of alcohol. Cox proportional hazard model was used to adjust for confounding factors. Results : Among males, compared to abstainer, heavy drinker had significantly higher mortality in all cause(Risk ratio=1.35), cardiovascular disease(Risk ratio=1.52) and cerebrovascular disease(Risk ratio =1.66). Although not significant, moderate drinker had lower ischemic heart disease mortality(Risk ratio =0.38). Among females, there was no statistically significant association between alcohol comsumption and mortality. Conclusion : The results of this study suggest that alcohol drinking has harmful effect on all-cause mortality, cardiovascular disease mortality and cerebrovascular disease mortality among males, especially in heavy drinker among males. Minimal evidence on protective effect for cardiovascular disease mortality in low or moderate drinker is observed.

• 문화기술의 융합
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• 제6권1호
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• pp.215-221
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• 2020

본 연구의 목적은 우리나라 만 65세 이상 노인의 심뇌혈관질환의 융복합적 관련요인을 규명하고, 노인 맞춤형 건강프로그램 개발의 기초자료로 활용하기 위함이다. 본 연구는 2017년도 국민건강영양조사결과를 기초자료로 한 이차자료 분석연구이며, 우리나라 만 65세 이상의 노인 1,617명을 대상으로 하였다. 자료 분석은 IBM 23 ver. SPSS를 이용하였다. 회귀분석 결과 65세 이상 노인의 심뇌혈관질환에는 건강관련요인 중 주관적 건강상태, 걷기실천여부 및 고콜레스테롤혈증이 관련이 있는 것으로 나타났다. 주관적 건강상태는 심뇌혈관질환 발생률이 '매우 좋음'일 경우보다 '좋음'일 경우 2.43배, '보통'일 경우 2.43배, ''나쁨'일 경우 2.39배 높았고, 매우 나쁨'일 경우에는 3.84배로 가장 높게 나타났다. 걷기실천여부는 걷기실천을 '하는 경우'보다 '하지 않는 경우'에 심뇌혈관질환의 발생이 1.44배 높게 나타났다. 고콜레스테롤혈증은 '없는 경우'보다 '있는 경우'에 심뇌혈관질환 발생률이 2.63배 높은 것으로 나타났다. 연구결과를 토대로 노인의 기저질환을 고려한 적극적인 예방적 간호중재 프로그램개발이 필요하다.

• 여성건강간호학회지
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• 제16권3호
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• pp.224-233
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• 2010

Purpose: This study explored the relationships among obesity, bone mineral density, and cardiovascular risks in post-menopausal women. Methods: One hundred post-menopausal women were recruited via convenience sampling from osteoporosis prevention program participants who were living in a metropolitan city in September 2006. Obesity was evaluated by body mass index, bone mineral density measured by DEXA scan, and cardiovascular risk factors assessed by a guideline of American Heart Association. Results: Seventy-two percent of women were either in the osteopenia or osteoporosis group, while 28% were in normal range in lumbar vertebrae. Obese women had greater bone mineral density in lumbar (F=3.31, p=.040) and femur (F=4.72, p=.011). Variables for cardiovascular risks were significantly different for high density lipoprotein (F=7.51, p=.001), systolic blood pressure (F=5.21, p=.007), and in percent of 10-year cardiovascular disease risk according to obesity. Conclusion: Post-menopausal women are at risk for obesity, osteoporosis, and cardiovascular disease. In order to prevent these conditions, nursing interventions such as resistance and aerobic exercise that reduces body weight and bone loss, increases high density lipoprotein, and reduces systolic blood pressure, should be proposed continually through health promotion programs for postmenopausal women.

• 한국융합학회논문지
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• 제10권12호
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• pp.135-142
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• 2019

본 연구에서는 동거형태에 따른 노인의 심혈관질환과 치주질환의 분포정도 및 관계를 분석하여 각각 특성에 맞는 프로그램 개발을 위한 기초 자료를 제공하기 위해 국민건강영양조사 제6기의 자료를 분석하였다. 일반적 특성에 따른 심혈관질환자의 분포는 가족동거노인의 경우 성별, 교육수준, 독거노인의 경우에는 나이, 소득수준에 따라 차이가 있었다. 구강건강상태 및 구강보건형태와 심혈관질환자의 분포는 가족동거노인의 경우 최근 1년간 치통경험이 있는 군, 최근 1년간 구강검진을 하지 않은 군, 치주염군, 독거노인은 구강건강상태가 나쁘다고 인지한 군과 치주질환 정상 군에서 더 많았다. 심혈관질환과 치주질환의 관계에서는 가족동거노인은 고혈압이 관련이 있었고 독거노인의 경우에는 관련이 없었다. 심혈관질환과 치주질환은 노인에게 가장 많은 질환이며 두 질환의 발생 연관성이 전혀 없다고는 할 수 없기 때문에 두 질환을 같이 고려하여 추후 건강상태 확인 및 다양한 가족동거 형태에 따른 차이점에 대해서 반복연구를 통해 구체적인 건강관리 방법이 논의되어야 한다.