• Title/Summary/Keyword: cardiovascular disease

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Can Yellow Fur on the Tongue be Useful as an Index of Cardiovascular Disease in Stroke Patients over 60 Years Old? - Multi Center Trial (60세 이상 뇌경색환자에서 황태는 심혈관질환의 유용한 지표가 될 수 있는가? - 다기관임상연구)

  • Leem, Jung-Tae;Park, Su-Kyung;Woo, Su-Kyung;Kwak, Seung-Hyuk;Jung, Woo-Sang;Moon, Sang-Kwan;Cho, Ki-Ho;Park, Sung-Wook;Ko, Chang-Nam
    • The Journal of Internal Korean Medicine
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    • v.31 no.3
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    • pp.569-577
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    • 2010
  • Background & Objectives : Yellow fur on the tongue is known to be associated with prognosis of disease in oriental medicine. Higher ratios of low-density lipoprotein cholesterol(LDL) to high-density lipoprotein cholesterol(HDL) & total cholesterol (TC) to high-density lipoprotein cholesterol(HDL) are associated with a greater risk of cardiovascular disease. The aim of this study was to assess the relationship between cardiovascular disease index and yellow fur - oriental medical index - in stroke patients over 60 years old. Methods & Subjects : Among 802 of the recruited patients(434 male, 368 female), 340 were yellow fur group(209 male, 131 female). We assessed their general characteristics and risk factors. We compared the cardiovascular disease index between yellow fur and non-yellow fur groups by sex. Results : On the General Characteristics males have yellow fur more often than females. In cardiovascular disease index, the male yellow fur group showed higher ratios of TC/HDL(atherogenic index), (TC-HDL)/HDL, LDL/HDL and higher LDL and showed lower HDL than the non-yellow fur group. In female patients, there were no differences between the two groups about cardiovascular disease index. There were more patients diagnosed with Fire & Heat in the male yellow fur group, and Dampness & Phlegm in the male non-yellow fur group. The male yellow fur group eat fast food more than the non-yellow fur group. Conclusions : The results indicated that yellow fur may be associated with a high risk of cardiovascular disease. We can thus use yellow fur on the tongue as a cardiovascular disease index in male stroke patients over 60 years old.

Tissue Microarrays in Biomedical Research

  • Chung, Joon-Yong;Kim, Nari;Joo, Hyun;Youm, Jae-Boum;Park, Won-Sun;Lee, Sang-Kyoung;Warda, Mohamad;Han, Jin
    • Bioinformatics and Biosystems
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    • v.1 no.1
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    • pp.28-37
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    • 2006
  • Recent studies in molecular biology and proteomics have identified a significant number of novel diagnostic, prognostic, and therapeutic disease markers. However, validation of these markers in clinical specimens with traditional histopathological techniques involves low throughput and is time consuming and labor intensive. Tissue microarrays (TMAs) offer a means of combining tens to hundreds of specimens of tissue onto a single slide for simultaneous analysis. This capability is particularly pertinent in the field of cancer for target verification of data obtained from cDNA micro arrays and protein expression profiling of tissues, as well as in epidemiology-based investigations using histochemical/immunohistochemical staining or in situ hybridization. In combination with automated image analysis, TMA technology can be used in the global cellular network analysis of tissues. In particular, this potential has generated much excitement in cardiovascular disease research. The following review discusses recent advances in the construction and application of TMAs and the opportunity for developing novel, highly sensitive diagnostic tools for the early detection of cardiovascular disease.

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First ClustalX-MPI for Ultra-fast Protein and Gene Discovery

  • Kim, Tae-Ho;Han, Jin;Youm, Jae-Boum;Kim, Na-Ri;Park, Won-Sun;Kang, Sung-Hyun;Cuong, Dang-Van;Kim, Hyoung-Kyu;Khoa, Tran Min;Thu, Vu Thi;Kim, Hyun-Ju;Moon, Hye-Jin;Lee, Hyun-Suk;Kim, Eui-Yong;Joo, Hyun
    • 한국생물공학회:학술대회논문집
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    • 2005.10a
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    • pp.296-296
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    • 2005
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MiDB: mitochondrial proteomics database in human heart

  • Kim, Tea-Ho;Joo, Hyun;Youm, Jae-Boum;Kim, Na-Ri;Park, Won-Sun;Kang, Sung-Hyun;Cuong, Dang-Van;Kim, Hyoung-Kyu;Khoa, Tran-Min;Thu, Vu-Thi;Kim, Hyun-Ju;Moon, Hye-Jin;Lee, Hyun-Suk;Kim, Eui-Yong;Han, Jin
    • 한국생물공학회:학술대회논문집
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    • 2005.10a
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    • pp.884-884
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    • 2005
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e-MITOCHONDRIA RESEARCH FOR SYSTEMS BIOLOGY AND PROTEOMICS

  • Joo, Hyun;Youm, Jae-Boum;Kim, Tae-Ho;Kim, Na-Ri;Park, Won-Sun;Kang, Sung-Hyun;Cuong, Dang Van;Kim, Hyoung-Kyu;Khoa, Tran Min;Thu, Vu Thi;Kim, Hyun-Ju;Moon, Hye-Jin;Lee, Hyun-Suk;Kim, Eui-Yong;Han, Jin
    • 한국생물공학회:학술대회논문집
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    • 2005.10a
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    • pp.295-295
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    • 2005
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Cardiovascular Disease Risk according to Socioeconomic Factors among Low-income Midlife Women (사회경제적 요인에 따른 지역사회 저소득층 중년여성의 심혈관질환 위험요인 차이)

  • Ham, Ok-Kyung;Kim, Bong-Jung;Lee, Young-Ah
    • Journal of Korean Public Health Nursing
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    • v.22 no.1
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    • pp.27-38
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    • 2008
  • Purpose: To determine the degree of cardiovascular disease risk according to socioeconomic factors among midlife women in the community and thereby provide baseline data for the development of health promotion programs. Method: A total of 200 women participated in health screenings and a health survey. The survey was performed in November and December, 2006. The survey instruments included socioeconomic factors, health behavior (smoking and exercise), and family history. Biophysical measurement included BMI and blood pressure. Blood samples were drawn for glucose and total cholesterol tests. Results: The mean age was 52.5 years, 34.0% had received education less than 6 years, 70.0% earned a monthly income of less than \1,500,000, and 61.5% were homemakers. Cardiovascular disease risk was significantly different by age (BMI, systolic BP, and exercise), education (systolic BP), monthly income (T. cholesterol), marital status (smoking), and occupation (exercise). Most women had 2 or 3 cardiovascular disease risks. Older age, lower education, and lower income were significantly associated with increased cardiovascular disease risk. Conclusion: Efforts should be made to decrease the number and severity of cardiovascular disease risk factors for midlife women in the community by developing health promotion programs targeting to modify their cardiovascular disease risk factors.

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Concept Analysis of Health Literacy for Patients with Cardiovascular Disease using Hybrid Model

  • Sim, Jeong Eun;Hwang, Seon Young
    • Research in Community and Public Health Nursing
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    • v.30 no.4
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    • pp.494-507
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    • 2019
  • Purpose: The purpose of this study is to provide a clear definition of the health literacy for patients with cardiovascular disease by analyzing the dimensions and properties using Hybrid concept analysis. Methods: The concept of health literacy of patients with cardiovascular disease was analyzed according to the cyclic process of theoretical phase-field work phase-final analysis phase presented in the Hybrid model. We reviewed 26 literatures and conducted in-depth interviews with 13 patients with cardiovascular disease. Results: The concept of health literacy in cardiovascular patients is derived from two dimensions and five attributes. Literacy skills, health information search ability and health information utilization skills were derived as attributes in the individual functional dimension, while active communication with the medical team and utilization of health information support resources were derived at the interrelational dimension. It is defined as the individualized and integrated ability of an individual to explore and utilize the various health information needed to make appropriate health decisions during the chronic course after diagnosis of cardiovascular disease, to communicate proactively with medical staffs and to utilize support resources. Conclusion: This study will contribute to the development and related research of health literacy measurement tools that can be used in cardiovascular nursing practice based on the attributes and indicators of health literacy for patients with cardiovascular disease.