• Geomechanics and Engineering
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• 제7권2호
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• pp.213-231
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• 2014

An elastoplastic model for structured clays, which is formulated based on the fact that the difference in mechanical behavior of structured and reconstituted clays is caused by the change of fabric in the post-yield deformation range, is present in this paper. This model is developed from an elastoplastic model for overconsolidated reconstituted clays, by considering that the variation in the yield surface of structured clays is similar to that of overconsolidated reconstituted clays. However, in order to describe the mechanical behavior of structured clays with precision, the model takes the bonding and parabolic strength envelope into consideration. Compared with the Cam-clay model, only two new parameters are required in the model for structured clays, which can be determined from isotropic compression and triaxial shear tests at different confining pressures. The comparison of model predictions and results of drained and undrained triaxial shear tests on four different marine clays shows that the model can capture reasonable well the strength and deformation characteristics of structured clays, including negative and positive dilatancy, strain-hardening and softening during shearing.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.3851-3864
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• 2014

Cytokine research is currently at the forefront in cancer research. Deciphering the functions of these multiple small molecules, discovered within the cell and in intercellular spaces, with their abundance and pleotrophism, was initially a great challenge. Advances in analytical chemistry and molecular biology have made it possible to unravel the pathophysiological functions of these polypeptides/proteins which are called interleukins, chemokines, monokines, lymphokines and growth factors. With more than 5 million women contracting cervical cancer every year this cancer is a major cause of mortality and morbidity the world over, particularly in the developing countries. In more than 95% of cases it is associated with human papilloma virus (HPV) infection which is persistent, particularly in those with a defective immune system. Although preventable, the mere magnitude of prevalence of HPV in the world population makes it a dominating current health hazard. The discovery of cytokine dysregulation in cervical cancer has spurted investigation into the possibility of using them as biomarkers in the early diagnosis of cases at high risk of developing cancer. Their critical role in carcinogenesis and progression of cervical cancer is now being revealed to a great extent. From diagnostics to prognosis, and now with a possible role in therapeutics and prevention of cervical cancer, the cytokines are being evaluated in all anticancer approaches. This review endeavours to capture the essence of the astonishing journey of cytokine research in cervical neoplasia.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2643-2646
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• 2012

Objectives: Human papillomavirus (HPV) is the major etiological agent of cervical cancer, a leading cause of morbidity and mortality in women worldwide. Screening strategies for reducing the burden of HPV-mediated carcinogenesis are emerging as an effective means for cervical cancer control and prevention in developing countries. Our study, therefore, aimed to identify HPV infection status in North Indian women during random population screening. Methodology: Cervical/vaginal exfoliated cells and/or Pap smear specimens were collected from 890 women of North Indian ethnicity residing in Lucknow and adjoining areas, during random population screening from June 2009-March 2012. HPV viral loads in clinical specimens were determined by the Hybrid Capture (hc)-2 HPV DNA assay, and subsequently, positive/negative/borderline HPV status was calculated. Results: The HPV incidence in the present study was 11.7%. 751 out of a total of 890 women (84.4%) participating in our HPV screening program were HPV negative (HPV -), 104 (11.7%) tested positive (HPV +) while 35 (3.9%) showed borderline (HPV $^*$) infection status. Furthermore, in the HPV + subjects (N=104), 18 (17.3%) showed strong positivity. We observed that HPV positivity tends to increase with age in North Indian women; the higher the viral load with increasing age, higher is the susceptibility to HPV-mediated cervical cancer. Conclusions: HPV viral load/genotyping may help in identifying women at risk of developing cervical cancer. However, cost-effective HPV screening protocols with a wider population coverage are warranted so as to reduce the burden of cervical cancer in women worldwide in the vaccine-era.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권7호
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• pp.3664-3677
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• 2017

Abrupt scene changes generally incur the afterimage effect. So, the unblocked image portion is still viewed by human eyes just after it is blocked by some pattern. Yovo's secure display method utilized this phenomenon and it is systematically analyzed using computational afterimage modeling by replacing the complex afterimage effect via simple low-pass filtering. With this approach, realistic images perceived by the human eye can be computationally generated at every single moment, especially reflecting the afterimage effect. The generated images are compared with the original images to determine the factors that affect the image quality of the secure display method. The simulation results demonstrate that the ratio of the unblocked portion to the blocked portion of an image and the playback rate are two primary factors related to the recognized image quality. We also found that the two factors are still effective for generalized secure display techniques.

• Journal of Communications and Networks
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• 제16권5호
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• pp.534-547
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• 2014

Large-scale failures resulting from natural disasters or intentional attacks are now causing serious concerns for communication network infrastructure, as the impact of large-scale network connection disruptions may cause significant costs for service providers and subscribers. In this paper, we propose a new framework for the analysis and prevention of network service disruptions in large-scale failure scenarios. We build dynamic deterministic and probabilistic models to capture the impact of regional failures as they evolve with time. A probabilistic failure model is proposed based on wave energy behaviour. Then, we develop a novel approach for preventive protection of the network in such probabilistic large-scale failure scenarios. We show that our method significantly improves uninterrupted delivery of data in the network and reduces service disruption times in large-scale regional failure scenarios.

• International journal of advanced smart convergence
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• 제10권4호
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• pp.30-37
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• 2021

Touch sensor interface has become the most useful input device in a smartphone. Unlike keypad/keyboard interfaces used in electronic dictionaries and feature phones, smartphone's touch interfaces allow for the recognition of various gestures that represent distinct features of each application's input. In this paper, we analyze application-specific input patterns that appear in smartphone's touch interfaces. Specifically, we capture touch input patterns from various Android applications, and analyze them. Based on this analysis, we observe a certain unique characteristics of application's touch input patterns. This can be utilized in various useful areas like user authentications, prevention of executing application by illegal users, or digital forensic based on logged touch patterns.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.811-816
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• 2007

The social activities of the elderly have been increasing as our society progresses toward an aging society. As their activities are increased, the occurrence of falls that could lead to fractures are increased. Falls are serious health hazards to the elderly and we need more thorough understanding of falls including the progress of falls and the impact area in various fall directions. Many of the traditional methods of falls research dealt with voluntary falls by younger subject since older subject can easily get fracture from voluntary falls. So, it has been difficult to get exact data about falls of the elderly. Here, we tried to capture the characteristics of the movements of major joints using three dimensional motion capture system during falls experiments using a moving mattress that can safely induce unexpected falls. Healthy younger subjects participated in the actual falls experiment and the moving mattress was actuated by a pneumatic system. The kinematic parameters such as velocities and accelerations of major segments were imported to a computer simulation environment and falls to hard surfaces were simulated in a computational environment using a realistic human model of aged persons. The simulation was able to give approximations to contact forces which can occur during actual falls.

• 한국운동역학회지
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• 제22권3호
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• pp.315-324
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• 2012

The purpose of current study was to investigate the effects of the heights on the lower extremities, torso and neck segments for energy dissipation during single-leg drop landing from different heights. Twenty eight young healthy male subjects(age: $23.21{\pm}1.66yr$, height: $176.03{\pm}4.22cm$, weight: $68.93{\pm}5.36kg$) were participated in this study. The subjects performed the single-leg drop landing from the various height(30, 45 & 60 cm). Force plates and motion-capture system were used to capture ground reaction force and kinematics data, respectively. The results were as follows. First, the ROM at the ankle, knee, hip and trunk was increased with the increased heights but the ROM at the neck was increased in the 60cm. Second, the angular velocity, moment and eccentric work at the ankle, knee, hip, trunk, and neck was increased with the increased heights. Third, the contribution to total work at the knee joint was not significantly different, while the ankle joint rate was decreased and hip and neck rate was increased in the 60cm, and trunk rate was increased with the increased heights. Lastly, the increase in landing height was able to augment the level of energy dissipation not only at the lower extremities but also at the trunk and neck. The findings showed that drop landing affect trunk and neck with lower extremity joints. Therefore, we need to consider that trunk and neck strengthening including stability should be added to reduce sports injury during prevention training.

• 한국해양공학회지
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• 제25권3호
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• pp.90-95
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• 2011

On April 20, 2010, a well control event allowed hydrocarbon (oil and gas) to escape from the Macondo well onto Deepwater Horizon (DWH), resulting in an exploration and fire on the rig. While 17 people were injured, 11 others lost their lives. The fire continued for 36 hours until the rig sank. Hydrocarbons continued to flow out from the reservoir through the well bore and blowout preventer (BOP) for 87 days, causing an unprecedented oil spill. Beyond Petroleum (BP) and the US federal government tried various methods to prevent the oil spill and to capture the spilled oil. The corresponding responses were very challenging due to the scale, intensity, and duration of the incident that occurred under extreme conditions in terms of pressure, temperature, and amount of flow. On July 15, a capping stack, which is another BOP on top of the existing BOP, was successfully installed, and the oil spill was stopped. After several tests and subsea responses, the well was permanently sealed by a relief well and a bottom kill on September 19. This paper analyzes the subsea responses and engineering efforts to capture the oil, stop the leaking, and kill the subsea well. During the investigation and analysis of subsea responses, information was collected and data bases were established for future accident prevention and the development of subsea engineering.

• Osong Public Health and Research Perspectives
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• 제5권4호
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• pp.187-192
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• 2014

Objectives: Measurement of the incidence of the human immunodeficiency virus (HIV) is very important for epidemiological studies. Here, we determined the recency period with the AxSYM avidity assay and the BED-capture enzyme immunoassay (BED-CEIA) in Korean seroconverters. Methods: Two hundred longitudinal specimens from 81 seroconverters with incident HIV infections that had been collected at the Korea National Institute of Health were subjected to the AxSYM avidity assay (cutoff = 0.8) and BED-CEIA (cutoff = 0.8). The statistical method used to estimate the recency period in recent HIV infections was nonparametric survival analyses. Sensitivity and specificity were calculated for 10-day increments from 120 days to 230 days to determine the recency period. Results: The mean recency period of the avidity assay and BED-CEIA using a survival method was 158 days [95% confidence interval (CI), 135-181 days] and 189 days (95% CI, 170-208 days), respectively. Based on the use of sensitivity and specificity, the mean recency period for the avidity assay and BED-CEIA was 150 days and 200 days, respectively. Conclusion: We determined the recency period to estimate HIV incidence in Korea. These data showed that the nonparametric survival analysis often led to shorter recency periods than analysis of sensitivity and specificity as a new method. These findings suggest that more data from seroconverters and other methodologies are needed to determine the recency period for estimating HIV incidence.