• 한국발생생물학회지:발생과생식
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• 제17권1호
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• pp.25-35
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• 2013

We investigated the effects of shell height on reproductive potential of the female Rapana venosa in three regions of different salinities (the coastal zone of the Gwangyang Bay (S-1); the upper reaches (S-3); lower reaches (S-2) of the Seomjin River). The number of egg capsules, egg capsule height, and fecundity associated with reproductive potential of larger female rapa whelks were higher than those of smaller individuals in all three regions. Correlation analyses showed that there is a significant positive correlation between egg capsule and female shell height. Mean of shell heights, egg capsule heights, the number of egg capsules in an egg mass, and fecundity in an egg capsule produced from female individuals inhabiting S-1 region were markedly higher than those inhabiting S-2 and S-3 regions. In particular, the fecundity of the rapa whelk increased with the salinity and shell height. Although large rapa whelks produced a large number of egg capsules at S-1 region, those at S-3 habitat laid less egg capsules with smaller size. If these rapa whelks were put into S-2 region, the number of egg capsules produced by a female at S-2 region was slightly larger than those produced by a female at S-3 region. This provides a clear evidence that the number of the egg capsules can be controlled by the salinity. In the coastal zone of the Gwangyang Bay and the upper reaches of Seomjin River, the fecundity of this species was estimated to be approximately 182,000-1,302,000 eggs/ind./yr.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.444-449
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• 2004

The design modification of bottom guide structures of the instrumented capsule, which is used for the irradiation test in the HANARO reactor, was required because of the trouble of the bottom guide arm's pin during irradiation. The previous structure with 3-pin arms was changed into the cone shape of one body. The specimens of the bottom end cap ring with three different sizes (${\Phi}68/70/72mm$) were designed and manufactured. The out-pile tests for the capsule with previous and new three bottom guide structures were performed in the one-channel flow test facilities. In order to evaluate the compatibility with HANARO and the structural integrity of the capsule, a loading/unloading, a pressure drop, a thermal performance, a vibration, and an endurance test were conducted. From out-pile test results, the capsule with the cone shape bottom guide structures was found to be more stable than the previous structure and the optimized size of the bottom guide structure selected was 70mm in diameter. It is expected that the new bottom guide structures will be applicable to all material and special capsules which will be designed and manufactured for the irradiation tests in the future.

• 한국전산유체공학회지
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• 제17권2호
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• pp.107-112
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• 2012

We explored the dynamic motions and the lateral equilibrium positions of an elastic capsule in channel flow at moderate Reynolds number varying Re, aspect ratio, size ratio, membrane stretching and bending coefficient. The transition of tank-treading/swinging to tumbling motion was observed in the simulations and the transition of dynamic motions for capsules resulted in different trend of the variation in the lateral equilibrium positions. Though other conditions were similar, the capsule with tumbling motion migrated closer to the wall than that with tank-treading motion.

• The Korean Journal of Ceramics
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• 제5권1호
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• pp.73-77
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• 1999

Capsule free hot isostatic pressing (HIPing) of 12 mol% $CeO_2-88 mo% ZrO_2 (12CeO_2-88ZrO_2)$ powder was conducted at 1100~$1200^{\circ}C$ using the powder crystallized in supercritical methanol followed by supercritical drying. Porous $12CeO_2-88ZrO_2$ ceramics with ~35% open porosity, micropore diameter of ~23 nm and a narrow pore size distribution were fabricated by capsule free hot isostatic pressing at $1100^{\circ}C$. The porosity increased with decrease in HIPing temperature and was accompanied by a steady decrease in fracture strength.

• 전기학회논문지
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• 제66권6호
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• pp.923-926
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• 2017

In this study, a novel wideband conformal thin antenna is presented for endoscopic capsule application at the 915 MHz Industrial, Scientific and Medical (ISM) band. The thickness of the antenna is only 0.2 mm which can be wrapped inside a capsule's inner wall. By cutting meandered slots on patch, open end slots on ground and utilizing long arm, the proposed antenna can obtain significant size reduction. The net volume of the proposed antenna including substrate and superstrate is only $37.4mm^3$ ($187mm^2$ surface area). This conformal antenna has shown good performance through simulation and measurement with maximum gain of -23 dBi and wide bandwidth from 137 MHz - 205 MHz depending on different environment. In addition, the effect of internal materials specially metallic battery is discussed briefly.

• 한국멀티미디어학회논문지
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• 제9권12호
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• pp.1669-1680
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• 2006

This paper explains that the RF systems for hi-directional wireless capsule endoscopes were designed and implemented. The designed RF systems for a capsule endoscope can transmit the images of intestines from the inside to the outside of a body and the behavior of the capsules can be controlled by an external controller simultaneously. The hi-directional wireless capsule endoscope consists of a CMOS image sensor, FPGA, LED, battery, DC to DC Converter, transmitter, receiver, and antennas. The transmitter and receiver which were used in the hi-directional capsule endoscope, were designed and fabricated with $10mm(diameter){\times}3.2mm(thickness)$ dimensions taking into the MPE, power consumption, system size, signal to noise ratio and modulation method. The RF systems designed and implemented for the hi-directional wireless capsule endoscopes system were verified by in-vivo experiments. As a result, the RF systems for the hi-directional wireless capsule endoscopes satisfied the design specifications.

• 한국어류학회지
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• 제22권4호
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• pp.217-224
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• 2010

참홍어(Raja pulchra)는 서해지역에서 산업적으로 활용도가 높고 개체군 크기의 축소가 예상되므로 인공증식 기술 개발과 보존을 위해 일련의 연구를 수행하였다. 이 연구는 연중 대형 난각의 형태로 다회 산란하는 특성과 완전한 형태로 부화하는 치어의 특징을 기록하였다. 난소 내 난은 평균 179.8 (54~247)개로 직경이 5가지 무리로 구분되어 순차적인 산란에 기여하는 특성을 보였다. 난각은 다른 홍어류의 종과 구분되는 특징적 구조를 보였으며, 하나의 난각내에 포함되는 배의 수는 2~6개 범위이었다. 아울러 난각내에서 발생하는 자어와 부출 직전에 해당하는 치어의 형태적 특징 및 변화를 분석하여 기술하였다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제5권5호
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• pp.345-349
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• 2000

To easily separate chitosanoligosaccharides by size exclusion, an coencapsulating technology of substrate and enzyme was developed. The membrane was composed of alginate and a divalent cation such as calcium. Chitosan and chitosanase were enveloped in this membrane and the product released to medium by size exclusion. The capsule was stabilized in a 2% acetic acid solution (pH 5.0) containing 0.145 M CaCO$_3$. The leakage of substrate caused by the agitation speed was controlled by increasing alginate and CaCO$_3$concentrations. The lower limit of the alginate concentration and the agitation speed were 0.5% and 49rpm, respectively. Membrane thickness and capsule diameter were 10$\mu\textrm{m}$ and 2.5mm, respectively. By TLC analysis, the composition of chitosanoligosaccharides were mainly 3-6 mers. The molecular weight distribution of the released oligosaccharides ranged from 262 to 3624 Da by GPC.

• 센서학회지
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• 제14권4호
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• pp.211-218
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• 2005

As the cause and the treatment about gastrointestinal disease has been issued recently, the importance of measuring the pressure in the gastrointestinal tract has been increased. However, the conventional measurement methods of the pressure in the gastrointestinal tract cause the patients' pain and inconvenience as well as an inaccurate pressure measurement. In this paper, the pressure monitoring telemetry system has been designed and implemented for an accurate pressure measurement inside the gastrointestinal tract with minimizing pain and inconvenience. The pressure monitoring telemetry system is composed of a pressure measurement capsule and an external receiver. The capsule has been miniaturized into the same size of a vitamin tablet so that the capsule can be swallowed through the oral cavity. After the capsule acquires and encodes the pressure data in the gastrointestinal tract, the encoded pressure data are modulated by frequency shift keying (FSK) and transmitted with ultrahigh frequency (UHF) band signal to the outside of a body. The performance of the telemetry capsule for monitoring pressure in the gastrointestinal tract is demonstrated by the results of animal in-vivo experiments.

• 대한의용생체공학회:의공학회지
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• 제40권1호
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• pp.7-14
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• 2019

The microencapsulation of nifedipine (NF) with 4 wt% of poly(${\varepsilon}-caprolactone$) (PCL)/polyvinylpyrollidone (PVP) or PCL/polyethylene glycol (PEG) was carried out by solvent evaporation method in oil in water emulsion system to investigate the effect of PVP and PEG addition on drug release behavior of the microcapsules. The PVA (emulsifier) concentration of 1.0 wt% was chosen for the formation of PCL capsule having an average size of $154{\pm}25{\mu}m$ due to nearly spherical shape with a narrow size distribution. As PCL/PVP and PCL/PEG ratios were raised from 10/0 to 6/4, the capsule size increased gradually from $154{\pm}25{\mu}m$ to $236{\pm}32{\mu}m$ and $248{\pm}56{\mu}m$, respectively. The drug release rate of PCL/PVP and PCL/PEG capsules increased dramatically from 0 to 4 h at the beginning and then reached the plateau region from 20 h. As the concentration of PVP or PEG increased, the amount of drug release increased, suggesting that the larger capsule size was attributed to the higher drug content. However, the drug release behavior remained almost constant. The PCL capsules exhibited no evidence of causing cell lysis or toxicity regardless of NF loading, implying that the microcapsules are clinically suitable for use as drug delivery systems.