• Clinical Endoscopy
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• 제51권6호
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• pp.563-569
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• 2018

Background/Aims: To evaluate patients with portal hypertension (PH) of varied etiologies for portal hypertensive enteropathy (PHE) using the PillCam SB3 capsule endoscopy (CE) system. Methods: Consecutive patients with PH presenting with unexplained anemia and/or occult gastrointestinal bleeding were evaluated using the PillCam SB3 CE system. Abnormal findings were categorized as vascular or non-vascular. The patients with ongoing bleeding caused by PHE were treated. The correlation of the CE scores of PHE with the clinical, laboratory, and endoscopic features was determined. Results: Of the 43 patients included in the study, 41 (95.3%) showed PHE findings. These included varices (67.4%), red spots (60.5%), erythema (44.2%), villous edema (46.5%), telangiectasia (16.3%), and polyps (16.3%). The CE scores varied from 0 to 8 ($mean{\pm}standard$ deviation, $4.09{\pm}1.8$). Five patients (11.6%) showed evidence of ongoing or recent bleeding due to PHE. Three of these five patients underwent endotherapy, and one patient underwent radiological coil placement. Conclusions: The PillCam SB3 CE system revealed a high prevalence of PHE in the patients with PH. Using this system, evidence of bleeding due to PHE was found in a small but definite proportion of the patients.

• Clinical Endoscopy
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• 제57권3호
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• pp.302-308
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• 2024

With incessant advances in information technology and its implications in all domains of our lives, artificial intelligence (AI) has emerged as a requirement for improved machine performance. This brings forth the query of how this can benefit endoscopists and improve both diagnostic and therapeutic endoscopy in each part of the gastrointestinal tract. Additionally, it also raises the question of the recent benefits and clinical usefulness of this new technology in daily endoscopic practice. There are two main categories of AI systems: computer-assisted detection (CADe) for lesion detection and computer-assisted diagnosis (CADx) for optical biopsy and lesion characterization. Quality assurance is the next step in the complete monitoring of high-quality colonoscopies. In all cases, computer-aided endoscopy is used, as the overall results rely on the physician. Video capsule endoscopy is a unique example in which a computer operates a device, stores multiple images, and performs an accurate diagnosis. While there are many expectations, we need to standardize and assess various software packages. It is important for healthcare providers to support this new development and make its use an obligation in daily clinical practice. In summary, AI represents a breakthrough in digestive endoscopy. Screening for gastric and colonic cancer detection should be improved, particularly outside expert centers. Prospective and multicenter trials are mandatory before introducing new software into clinical practice.

• Clinical Endoscopy
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• 제56권3호
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• pp.283-289
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• 2023

Gastrointestinal (GI) bleeding is one of the most common conditions among patients visiting emergency departments in Korea. GI bleeding is divided into upper and lower GI bleeding, according to the bleeding site. GI bleeding is also divided into overt and occult GI bleeding based on bleeding characteristics. In addition, obscure GI bleeding refers to recurrent or persistent GI bleeding from a source that cannot be identified after esophagogastroduodenoscopy or colonoscopy. The small intestine is the largest part of the alimentary tract. It extends from the pylorus to the cecum. The small intestine is difficult to access owing to its long length. Moreover, it is not fixed to the abdominal cavity. When hemorrhage occurs in the small intestine, the source cannot be found in many cases because of the characteristics of the small intestine. In practice, small-intestinal bleeding accounts for most of the obscure GI bleeding. Therefore, in this review, we introduce and describe systemic approaches and examination methods, including video capsule endoscopy and balloon enteroscopy, that can be performed in patients with suspected small bowel bleeding in clinical practice.

• Clinical Endoscopy
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• 제55권4호
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• pp.532-539
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• 2022

Background/Aims: Capsule enteroscopy (CE) and intestinal ultrasonography (IUS) are techniques that are currently used for investigating small-bowel (SB) diseases. The aim of this study was to compare the main imaging findings and the lesion detection rate (LDR) of CE and IUS in different clinical scenarios involving the SB. Methods: We retrospectively enrolled patients who underwent CE and IUS for obscure gastrointestinal bleeding (OGIB), complicated celiac disease (CeD), and suspected or known inflammatory bowel disease (IBD). We evaluated the LDR of both techniques. The accuracy of IUS was determined using CE as the reference standard. Results: A total of 159 patients (113 female; mean age, 49±19 years) were enrolled. The LDR was 55% and 33% for CE and IUS (p<0.05), respectively. Subgroup analysis showed that the LDR of CE was significantly higher than that of IUS in patients with OGIB (62% vs. 14%, p<0.05) and CeD (55% vs. 35%, p<0.05). IUS showed a similar LDR to CE in patients with suspected or known IBD (51% vs. 46%, p=0.83). Conclusions: CE should be preferred in cases of OGIB and CeD, whereas IUS should be considered an early step in the diagnosis and follow-up of IBD even in patients with a proximal SB localization of the disease.

• Clinical Endoscopy
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• 제57권2호
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• pp.203-208
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• 2024

Background/Aims: Upper gastrointestinal bleeding (UGIB) is the most common GI condition requiring hospitalization. The present study aimed to evaluate the safety and feasibility of using the PillSense system (EnteraSense Ltd.), a novel diagnostic tool designed for the rapid in vivo detection of UGIB, in human volunteers. Methods: In the present study, 10 volunteers swallowed a PillSense capsule, followed by 2 servings of an autologous blood preparation. Participants were monitored for capsule passage, overall tolerability of the procedure, and adverse events. Results: The procedure was completed per the protocol established in the present study in 9/10 cases. In 9 of the subjects, after capsule ingestion, the device indicated the absence of blood with sensor output values of 1. After the ingestion of the first blood mixture, the sensor outputs of all devices increased to a range from 2.8 to 4, indicating that each sensor capsule detected blood. The sensor output remained within that range after the ingestion of the second mixture; however, in one case, the baseline capsule signal was positive, because of a preexisting condition. The passage of the capsule was verified in all patients, and no adverse events were reported. Conclusions: The first trial of the PillSense system in human subjects demonstrated the feasibility, safety, and tolerability of utilizing this product as a novel, noninvasive, and easy-to-use triage tool for the diagnosis of patients suspected of having UGIB.

• 중소기업융합학회논문지
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• 제4권2호
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• pp.33-39
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• 2014

본 논문에서는 효율적인 제어를 위하여 캡슐 앤도스코피에 대한 모델링을 실시하였다. 방법론적으로 루그레 모델에 대한 시스템 특성파악을 위한 수학적 모델링을 이용하였다. 비선형 마찰 모델인 루그레 모델에 바탕을 둔 stick-slip 모션 시스템이 인체내에서의 캡슐 앤도스코피의 활동을 묘사하는 시뮬레이션 모델로 이용하였다. 다양한 상황을 고려하여 루그레 마찰모델에 대한 시뮬레이션을 Matlab Simulink 를 작성하여 수행하였다. 전체적인 모션과 파라미터의 영향이 엔도스코피의 속도에 미치는 영향에 대한 것에 주안을 두어 실시하였다.

• Clinical Endoscopy
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• 제51권6호
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• pp.505-507
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• 2018

• 대한의용생체공학회:의공학회지
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• 제43권6호
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• pp.417-423
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• 2022

The present study proposed a new interface system for capsule endoscopy by using head mounted display (HMD) device, which can control the orientation of the capsule endoscope with electromagnetic actuator (EMA) system. The orientation information of the HMD user was detected by the gyroscope sensor built into the device and then calculated to as an angle increment using Unity Engine compiler. The measured angle changes from the HMD were converted to the current values of the corresponding coils to be changed in the EMA system. Two experiments were designed to measure the accuracy and the intuitiveness of the HMD interface system. In the angle accuracy measurement, the capsule endoscope driven by HMD interface system showed the averaged errors of 0.68 degrees horizontally and 1.001 degrees vertically for given test angles. In the intuitiveness measurement, HMD interface system showed 1.33 times faster manipulation speed rather than the joystick interface system. In this respect, the HMD interface system for capsule endoscopy was expected to improve the overall diagnostic environment while maintaining comfort of patients and clinicians.

• Journal of information and communication convergence engineering
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• 제16권2호
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• pp.130-134
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• 2018

Wireless capsule endoscopy (WCE) is considered as recent technology for the detection cancer cells in the human digestive system. WCE sends the captured information from inside the body to a sensor on the skin surface through a wireless medium. In WCE, the design of low-power consumption devices is a challenging topic. In the Shannon-Nyquist sampling theorem, the number of samples should be at least twice the highest transmission frequency to reconstruct precise signals. The number of samples is proportional to the power consumption in wireless communication. This paper proposes compressive sensing as a method to reduce power consumption in WCE, by means of a trade-off between samples and reconstruction accuracy. The proposed scheme is validated under channel constraints, expressed as the realistic human body path loss. The results show that the proposed scheme achieves a significant reduction in WCE power consumption and achieves a faster computation time with low signal error reconstruction.

• 중소기업융합학회논문지
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• 제4권1호
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• pp.17-29
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• 2014

무선 캡슐 내시경은 소장 질환을 진단하는 등의 어려움을 해결하는 진화 의료 기기로서 중요한 역할을 했다. 그것은 제한된 크기와 기능 때문에 몇 가지 단점이 있다. 가장 큰 장애물은 자기 운동 장애에서 속도 문제를 제공할 수 없다는 점이다. 따라서, 인간의 소화 시스템의 특성을 간단히 내시경 역학의 정보를 얻기 위해, 특히 소장을 소개한다. 조건 추출을 확인하기 위해서 LuGre 모델이라는 새로운 동적 마찰 모델을 도입하고 명확하게 특성 및 모델의 사용을 얻기 위하여 분석한다. 캡슐 내시경의 실제 상황과 관련된 매개 변수의 고려하여 매트랩 시뮬링크는 모델을 작성하는 데 적용하고 기능을 발견 할 수있는 시뮬레이션을 통해 확인하였다.