• 대한간호학회지
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• 제49권3호
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• pp.263-273
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• 2019

Purpose: The purpose of the study was to explore the experience of patients with facial burn injuries regarding their interpersonal relationships. Methods: The phenomenological research method was used. Participants of the study consisted of five males and three females. Data were collected through individual in-depth interviews from November, 2014 to February, 2015 and analyzed using Colaizzi's method. Results: Five theme clusters were extracted that described patients' experiences. They are "being a lonely foreigner," "closing my mind toward the world," "hiding hurt feelings," "companion of my face," and "communicating with the world". Conclusion: The results of this study provide a deep understanding and insight into the experience of interpersonal relationships among facial burn patients. The development of a comprehensive program including physical, psychological, and social aspects is recommended to address the problems facial burn patients encounter in interpersonal relationships and to facilitate interaction.

• 한국환경복원기술학회지
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• 제12권5호
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• pp.28-41
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• 2009

Because fire has significant impacts on fauna and flora in forest ecosystems, as well as socioeconomic influences to local community, it has been an important field of study for decades. One of the most common ways to reduce fire risk is to enhance fire-resilience of forest through fuel treatments including thinning and prescribed burning. Since fuel treatment can't be practiced over all forested areas, appropriate and effective strategies are needed. The present study aims to look at the relationship between spatial characteristics of forest structure measured with landscape pattern metrics and burn severity to provide guidelines for effective fuel treatments. Samchuck fire was selected for the study, and 232 grids covering the study areas were generated, and the grid size was 1km. The burn severity is measured with dNBR derived from satellite imagery, and spatial characteristics of forest structure were measured using FRAGSTATS for both landscape and class levels for each 1km grid. The results of this study strongly indicated that heterogeneity in composition and configuration of forests may significantly reduce burn severity. By enhancing heterogeneity of forests, fuel treatments for fire-resilience forest could be more effective.

• 한방재활의학과학회지
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• 제24권3호
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• pp.87-98
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• 2014

Objectives The present study aimed to investigate the effects of acupuncture and herbal external preparation on wound healing procedure in a deep partial thickness burn model in rats. Methods A total of 40 male Sprague-Dawley rats were allocated into four groups with an equal number in each group: acupuncture treatment group, herbal external perparation group, Silver sulfadiazine dressing group and control group. We describe the effect of acupuncture and herbal external preparation on morphologic and histologic changes, epithelial growth factor (EGF), hematological value of the deep partial thickness burn wound in rats. Results At 21th day after wounding the wound size in acupuncture treat group and herbal external preparation group were decreased more significantly compared to control group. In addition, epidermal regeneration on acupuncture treatment was than other treatment and control group in histological finding. Hematological findings revealed that acupuncture treatment group and herbal external prepartion group was more effective than control group in reducing inflammation response induced by burn. In acupuncture treated group, neutrophil and leukocyte level were significantly decreased compared to other treatment group. Also, this study showed that EGF was obviously expressed in nascent tissue when wounds were treated with the acupuncture and herbal external preparation after injury. In particular, acupuncture treatment group had a significant increase of EGF expression in burn wound healing area when compared with the other treatment groups. Conclusions These findings suggest that acupuncture and herbal external prepration may improve burn wound healing through decreasing inflammatory reaction, increasing tissue regeneration and expression of EGF. Moreover, acupuncture treatment could be more effective in comparison with Silver sulfadiazine dressing.

• BMB Reports
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• 제46권1호
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• pp.47-52
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• 2013

Intestinal epithelial cell (IEC) apoptosis induced by hypoxia compromise intestinal epithelium barrier function. Both Akt and Hsp90 have cytoprotective function. However, the specific role of Akt and $Hsp90{\beta}$ in IEC apoptosis induced by hypoxia has not been explored. We confirmed that hypoxia-induced apoptosis was reduced by $Hsp90{\beta}$ overexpression but enhanced by decreasing $Hsp90{\beta}$ expression. $Hsp90{\beta}$ overexpression enhanced BAD phosphorylation and thus reduced mitochondrial release of cytochrome C. Reducing $Hsp90{\beta}$ expression had opposite effects. The protective effect of $Hsp90{\beta}$ against apoptosis was negated by LY294002, an Akt inhibitor. Further study showed that Akt phosphorylation was enhanced by $Hsp90{\beta}$, which was not due to the activation of upstream PI3K and PDK1 but because of stabilization of pAkt via direct interaction between $Hsp90{\beta}$ and pAkt. These results demonstrate that $Hsp90{\beta}$ may play a significant role in protecting IECs from hypoxia-induced apoptosis via stabilizing pAkt to phosphorylate BAD and reduce cytochrome C release.

• Animal cells and systems
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• 제16권3호
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• pp.207-214
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• 2012

Burns are one of the most devastating forms of trauma and wound healing is a complex and multicellular process, which is executed and regulated by signaling networks involving numerous growth factors, cytokines, and chemokines. Recombinant human granulocyte macrophage colony-stimulating factor (rhGM-CSF) was specifically produced from rice cell culture through use of a recombinant technique in our laboratory. The effect of rhGM-CSF on promotion of deep second-degree burn wound healing on the back skin of a hamster model was evaluated through a randomized and double-blind trial. As macroscopic results, hamster skins of the experimental groups showed earlier recovery by new epidermis than the control groups. Immunohistochemical reactions of proliferating cell nuclear antigen and transforming growth factor-b1, which are indicators of cell proliferation, were more active in the experimental group, compared with the control group. On electron microscopy, basal cells in the epidermis of the experimental group showed oval nuclei, prominent nucleoli, numerous mitochondria and abundant free ribosomes. In addition, fibroblasts contained well-developed rough endoplasmic reticulum with dilated cisternae. Bundles of collagen fibrils filled the extracellular spaces. Particularly, ultrastructural features indicating active metabolism for regeneration of injured skin at 15 days after burn injury, including abundant euchromatin, plentiful free ribosomes, and numerous mitochondria, were observed. These findings suggest that use of rhGM-CSF could result in accelerated deep second-degree burn wound healing in animal models.

• 대한불안의학회지
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• 제8권2호
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• pp.93-98
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• 2012

Objective : Cortisol, a product of hypothalamus-pituitary-adrenal axis (HPA axis), is one of our defensive mechanisms in response to stress. The level of cortisol in the saliva is a major biomarker of the stress response by HPA axis and shows diurnal variation. We measured salivary cortisol level and its diurnal variation to compare the pattern of changes by degree of burn and Clinician-Administered PTSD Scale (CAPS) score. Methods : We measured the salivary cortisol levels of 37 subjects hospitalized in the burn center at our facility from March to June 2012. Salivary cortisol levels were measured at 6 : 00 AM and at 7 : 00 PM. All subjects were tested for CAPS to evaluate the severity of posttraumatic stress disorder and the Hamilton Depression Rating Scale to evaluate and to control the coexisting depression. Results : Factorial ANOVA test revealed that there was a statistically significant difference in terms of the effect of the interaction between the degree of burn and the patient's CAPS score. Unlike the mild burn group, in the severe burn group, the patients who had a low CAPS score didn't show a normal diurnal variation and the patients who had a high CAPS score showed the normal diurnal variation. After a few months follow up, we found a greater degree of psychiatric complications in severe burn patients that had a lower cortisol stress response. Conclusion : We suppose that the disappearance of the stress response changes in salivary cortisol seen in the severe burn group may be caused by an impaired stress response. Through followed observation of the subjects, this disruption of cortisol response may cause psychiatric problems afterwards.

• 한국철도학회논문집
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• 제15권6호
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• pp.566-571
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• 2012

도시철도차량의 출입문 장치는 중정비 6년 검사에서 총 75종 단위부품 중 34종 75개의 부품을 정기적으로 교체하며, 나머지 비정기 교환부품인 40종 68개 부품도 필요 시 교체하고 있어 사실상 초기제품에 가까운 상태가 되며, 한편으로는 기존 부품과 다수의 교환된 부품이 혼용 사용되면서 완전한 신품과는 또 다른 제품특성을 가지게 된다. 본 연구는 이러한 출입문 장치의 정비 후 특징을 고려하여 도시철도차량의 신뢰성을 향상하는 방법으로 번인시험을 제안하며 시험에 적합한 조건과 목표 값을 새롭게 제시하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제12권3호
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• pp.63-67
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• 1990

Electrical burns of the lips are most frequently seen in small children, who are apt to chew on electrical cord or plug, the ends of extension cords in their mouth, saliva creates a short circuit across the terminals within the plug, causing an electrical burn. Tissue destruction with electrical burns is sudden and extensive. Extensive, deep coagulation necrosis is instaneously produced by the extreme temparatures of electrical arc. If the child is well grounded, the circuit flow through his body may cause cardiac arrest. The purpose of this report is to document two cases of electrical lip burn and reconstruction of the lip defect with some local flap techniques. For case 1, Z plasty & V-Y plasty and lengthening of the commissure and in case 2, Abbe flap technique was used and scar was revised later. Z-plasty and V-Y plastry were used for scar release and Abbe flap was designed on lower lip to meet the need of upper lip. For short of right lip width, lengthening of the commissure was done. We are to report the improvement with forementioned operation on the patient of electrical burn upon the lip.

• Carbon letters
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• 제8권4호
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• pp.299-306
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• 2007

Four stream- activated carbons were prepared by carbonizing apricot stones at $600^{\circ}C$ followed by gasification with steam at $950^{\circ}C$ to burn-off's=17, 32, 49 and 65%. The textural parameters of these activated carbons were determined from nitrogen adsorption results at 77 K. The total pore volume and the mean pore radius increased with the increase of % burn-off whereas the surface area increased with the increase of burn- off from 17 to 32 and further to 49%. Further increase of burn-off to 65% was associated with a considerable decrease in surface area as a result of pronounced pore widening due to pore erosion. The surface pH values of the carbons investigated range between 7.1 and 8.2. The adsorption of oxamyl onto the activated carbon followed pseudo-second order kinetics and the equilibrium adsorption isotherms fitted Langmuir adsorption model. The adsorption of oxamyl proved to be of the physical type and took place in non-micropores. The amount of oxamyl adsorbed expressed as $q_m$ depends to a large extent to the surface area located in non-micropores $S^{\propto}\;_n$, where a straight line relationship passing through the origin was obtained.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2014년도 추계학술대회 논문집
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• pp.911-915
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• 2014

Pyrotechnic devices are widely used for space appendages. However, a cube satellite requirements do not permit the use of explosive pyrotechnic device. A nichrome burn wire release has typically been used for holding and release of deployable appendages of the cube satellite due to its simplicity and low cost. However, relatively low mechanical constraint force and system complexity for application of multi-deployable systems are disadvantages of the conventional mechanism. To overcome these drawbacks, we have developed a segmented nut type holding and release mechanism based on the nichrome burn wire release. The great advantages of the mechanism are much lower shock level and larger constraint force than the conventional mechanism using pyro. Flight model for on-orbit verification was developed and verified through release function test, vibration test and thermal vacuum test.