• Journal of Chest Surgery
• /
• 제27권12호
• /
• pp.1002-1007
• /
• 1994

The spontaneous pneumothorax occurs subsequent to a disruption in the continuity of the visceral pleura with escape of free air into the pleural space included primary & secondary pneumothorax that is unrelated to identifiable etiologies such as trauma. In. the 33 year period 1960 to 1993, the 230 cases of open thoracotomy were carried out for definitive treatment of spontaneous pneumothorax, at the Dept. of Thoracic & Cardiovascular Surgery, National Medical Center, Seoul, Korea. There were 193 men & 37 women. They ranged in age from 15 years old to 72 years old. The lesion site was on the right side in 117 and on the left in 97, the 16 cases were in bilateral lesions.Surgical indications included recurrence in 98 cases, persistent air leak in 68 cases, nonexpansion of the lung 37 cases, roentgenologically apparent bullae & blebs in 23 cases, bilateral lesions in 16 cases,combined hemothorax & prevent for recurrence in each 2 cases. The types of operation were bullectomy in 207 cases, wedge resection in 13 cases, decortication & B.P.F. closure in 6 cases,lobectomy in 2 cases, pneumonectomy, plication in each I case. The post operative complication developed in 18 cases[7.8 %], there was I case of death due to sepsis. We believed that open thoracotomy with resection or obliteration of blebs & pleurodes is provided the best protection against recurrence.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제31권5호
• /
• pp.414-418
• /
• 2009

Pemphigus vulgaris is a chronic autoimmune intraepithelial blistering disease with oral mucosal manifestations that very often precede the skin lesions. The vesicles or bullae are produced by an acantholytic process, detachment of differentiating keratinocytes from one another in the epithelial stratum spino sum or spinous cell layer. The pathogenesis of this disease is initially manifested by IgG(mainly) binding to desmosome(desmoglein 3 or 1) in the intercellular spaces of epithelium. This autoantibody binding caused the release of a plasminogen activator(a proteolytic enzyme) from keratinocytes. This ultimately results in cell to cell separation. The mainstay therapy of pemphigus vulgaris is systemic corticosteroids and immunosuppressive agents to eliminate the pathogenic autoantibodies from circulation. A 41-year old woman presented with a 1.5 year history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with pemphigus vulgaris. Control of oral ulceration and normal oral function were achieved after systemic corticosteroids and immunosuppressive agents were instituted.

• Journal of Chest Surgery
• /
• 제18권4호
• /
• pp.822-834
• /
• 1985

Reexpansion of the lung is the most desirable method of filling the pleural space whether it`s contents may be, and closed thoracotomy connected to a water-seal drainage remains the basic therapeutic modality in the treatment of the problems of the pleural space. We usually used rubber mushroom tubes, size No. from 16 to 34 Fr., and performed closed thoracotomy after preliminary thoracentesis to determine the exact depending position. Author reviewed 576 cases of closed thoracotomy which were performed in the Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital, since Jan., 1980 to June, 1984. The results were as follows: 1. The age distribution was 10 days to 76 years old and mean age of the patients was 36.6 year, and the most prevalent age group was twenties, and sex predisposition was male dominant, 86.9%. 2. The most common etiologic disease group was pneumothorax and the most common etiologic disease was traumatic hemothorax. 3. Sites of tubing were predominantly at posterior axillary line, 7th intercostal space and midclavicular line, 2nd intercostal space even though frequent presence of free pleural space. The two sides, right and left difference of occurrence rate was more frequent at right side, 51.2%. 4. Usually the durations of tubing was less than 10 days, 52.6%, and the number of tubes used to the same patient concomitantly was one, 73.9%, and the time of tubing to the same patient was 1st, 83.6%. 5. The common symptom and sign were dyspnea, 50.0%, chest pain, 30.7%, cough, 10.7%, fever, 6.5%. Especially, fever and cough was the most common symptom and sign in pyogenic empyema, 59.3%. 6. The common etiologic lesions of pneumothorax were blebs and bullae, 73.3%, and of pyogenic empyema was pneumonia, 69.0%. 7. The complication rate of closed thoracotomy was 26.0%. Among these complications, infection was 44.7%, and intercostal neuralgia was 25.3%. 8. 70.9% of all patients recovered with only closed thoracotomy and the rest of patient needed additional some necessary managements such as open thoracotomy [Blebectomy, Resection, Pleurodesis, Decortication, Bleeding control], open drainage, thoracoplasty and so on to have successful results.

• Archives of Hand and Microsurgery
• /
• 제23권4호
• /
• pp.271-276
• /
• 2018

60세 남성이 3개월간 좌측 새끼손가락이 붓고 그곳의 발적 증상을 주소로 내원하였다. 과거력 상 특이 소견은 없었고, 균 배양 검사상 methicillin-resistant Staphylococcus aureus가 검출되었다. 반코마이신을 투여 후, 피부 병변이 악화되면서 전신 수포와 낙설이 발생하였다. 우리는 처음에 약물 발진 의진 하에 항생제를 반코마이신에서 테이코플라닌으로 변경하였다. 하지만 피부 조직검사 결과는 Staphylococcal scalded skin syndrome (SSSS)으로 나왔다. 수일 후, 환자는 전신 피부증상 호전되어 퇴원하였다. 우리는 건강한 성인에서 발생한 국소적 양상의 SSSS에 대해 보고하고자 한다. 이는 오진하기 쉬운 증례로서, 정확한 진단을 위하여서는 조기에 조직학적 검사가 중요할 것으로 생각된다.

• Journal of Chest Surgery
• /
• 제54권1호
• /
• pp.53-58
• /
• 2021

Background: We aimed to investigate the characteristics of primary spontaneous pneumothorax (PSP) in adolescents and to analyze the relationship between the occurrence of PSP and air pollutants. Methods: Data pertaining to age, sex, body mass index, smoking status, initial pneumothorax volume, presence of bullae, treatment methods, and city of residence were retrospectively obtained from January 2010 to December 2014. We investigated the association between short-term exposure to air pollutants (SO2, NO2, O3, CO, and PM10) and the occurrence of PSP using a case-crossover design with conditional logistic regression. Results: We collected information from 598 patients who were admitted for PSP, with a mean follow-up duration of 62.9 months. The majority (91.1%) of the patients were male. In the case-crossover design, conditional logistic regression showed that no air pollutant was associated with the occurrence of pneumothorax. The results were consistent across all city subgroups (Anyang, Gunpo, Uiwang, and Gwacheon). Conclusion: In our study, the incidence rate of pneumothorax was 153.8 per 100,000 person-years in male adolescents and 16.7 per 100,000 person-years in female adolescents. The case-crossover design showed that PSP in adolescents is unlikely to be related to air pollution.

• Tuberculosis and Respiratory Diseases
• /
• 제71권6호
• /
• pp.438-444
• /
• 2011

Background: Lung abscess is necrosis of the pulmonary parenchyma caused by microbial infection. At present, clinical outcomes after treatment are good. However, the pulmonary parenchymal changes on the chest computed tomography (CT) after treatment are not well known. We studied the changes of pulmonary parenchyma on plane chest radiography and chest CT in patients with lung abscess following the administration of antibiotics. Methods: We retrospectively reviewed 39 patients who had lung abscess with or without combined pneumonia from January 2006 to July 2010. We studied the therapeutic response in plane chest radiography of them at 1, 2, or more than 3 months following treatment. If any chest CT of them during the study period, we reviewed. Results: Mean age of the patients was about $61.3{\pm}11.2$. Mean duration of antibiotics administration was about $36.7{\pm}26.8$ days. After 3 months of following plane chest radiography, 10 patients (36%) showed without residual sequelae among 28 patients. Findings from other patients showed decrease in densities (11 patients, 39%), fibrostreaky sequelae (4 patients, 14%) and bullae (3 patients, 10%). After more than 2 months, chest CT was checked only in 7 patients. Among the 7 patients, 4 patients showed no residual lesion, 3 patients showed decreased densities on plane chest radiography. Chest CT revealed fibrostreaky densities in 2 patients, ground glass opacities in 3 patients, bullous formation in 1 patient, and cystic bronchiectasis in 1 patient. Conclusion: After more than 2 months following treatment for lung abscess even though there were no lesions on plane chest radiography, chest CT showed fibrostreaky or ground glass opacity.

• Journal of Chest Surgery
• /
• 제31권11호
• /
• pp.1076-1080
• /
• 1998

연구배경 : 자연성 기흉은 흉부외과 영역에서 흔히 접하게 되는 질환 중의 하나로서 주로 젊은 연령층의 키 크고 마른 남자의 경우 호발하며 뚜렷한 유발 인자 없이 기포의 파열로 인해 발생하나, 흉강 내 혈액이 같이 축적되는 자연성 혈기흉은 드문 질환 으로 알려져 있다. 재료 및 방법 : 인제대학교 부산백병원 흉부외과학 교실에서는 1990년부터 1997년까지 최근 8년간 자연성 혈기흉 15례를 경험하여 다음과 같은 결과를 얻었다. 결과 : 남녀 비는 14:1로 남자가 대부분이었으며 30대 이하가 14례로 전체의 93.3%를 차지하였다. 발생부위는 우측이 10례 좌측이 5례였으며 내원시 흉통 및 흉부 불쾌감, 호흡곤란 등을 호소하는 경우가 대부분 이였고 과다 출혈로 인한 쇼크 현상을 나타낸 경우가 1례 있었다. 원인으로는 유착 파열이 14례였으며 내인성 폐질환인 결핵이 1례였다. 전례에서 폐쇄식 흉강삽관술을 시행하여 대부분 특별한 문제없이 치유되었으나 전원되었던 1례에서 지속적인 출혈로 발병 3일 후 개흉술을 시행하였다. 그 외 폐쇄식 흉강삽관술로 치료한 30일 및 50일 후에 발생한 섬유흉과 동측의 기흉으로 늑막박피술과 폐쇄기절제술을 시행한 경우가 각 1례씩 있었다. 결론 : 자연성 혈기흉의 치료에는 흉강천자, 폐쇄식 흉강삽관술, 비디오 흉강경 수술, 개흉술 등이 있으며 발병 후 환자의 내원이 빠른 시간 내에 이루어지고 지속적 출혈이 없다면 단순한 폐쇄식 흉강삽관술 만으로도 대부분 특별한 합병증 없이 치료가 가능할 것으로 사료된다.

• Journal of Chest Surgery
• /
• 제29권10호
• /
• pp.1133-1137
• /
• 1996

흉강경을 이용한 흉부수술의 경우 최근 들어 상당한 발전이 계속되면서 시술할 수 있는 분야가 크게 증가하였다. 중앙대학교 흉부외과에서는 1994년 9월부터 1995년 8월까지 비디오흉강경을 이용한 수술 67례의 임상결과를 보고하는 바이다. 1. 진단은 기흉 35례, 미만성 간질성 폐질환 9례, 농흉 7례, 폐암에 의한 삼출액 3례, 다한증 3례, 흉강내 이물질 2례, 중피종 1례, 속립성 폐결핵 1례, 기질화된 폐렴 1례였다 2. 수술은 기흉환자 35례중 흉막 유착이 심하여 개흉술로 전환한 2례를 제외한 33례 에서 비디오 흉강경 기포절제술을 시행하였다. 그외에 흉강경을 이용한 지혈 5례, 세척술 7례, 이물질 제거 2례, 악성 늑막 삼출시 활석분무 3례, 교감신경 절제 술을 3례 시행하였다. 흉강경적 생검은 12례 시행하였다. 3. 기흉환자중 재발성 기흉으로 18례 수술하였고 지속적 공기누출 12례, 단순흉부사진상 기포가 보인 례가 5례 있었다. 심한 유착을 보여 흉강경에서 전환한 개흉적 기포제거술 2례를 시행하였다. 4. 비디오흉강경적 생검을시행한 12례의 병리학적 소견은 특발성 폐섬유화증 9례, 속립성 결핵 1례, 중피종 1례 및 기질화된 폐염 1례였다. \ulcorner鈒\ulcorner폐섬유화증 9례중 7례는 박리성 간질성 폐염, 2례는 통상 성 간질성 폐염이었다. 5. 비디오흉강경 67례중에서 63례에서 특별한 합병증 없이 퇴원하였고 4례에서 합병증이 발생하였다. 2 례가 계속된 공기누출, 2례는 반대측의 무기폐가 발생하였다. 따라서 비디오홍강경 수술은 비교적 안전하고 합병증이 적으며 앞으로 흉부수술영역에서 사용범위가 확대될 것으로 생각된다.

• Journal of Chest Surgery
• /
• 제41권6호
• /
• pp.724-728
• /
• 2008

배경: 본원에서 자발성 기흉으로 흉강경을 이용 폐 쐐기절제술 후 퇴원한 환자가운데 재발로 수술을 다시 받은 환자에서 기흉의 재발에 관한 위험 인자에 대해 연구하였다. 대상 및 방법: 2002년 1월부터 2005년 12월까지 본원 흉부외과에서 흉강경을 이용하여 흉막 유착술 없이 폐 쐐기절제술만을 시행한 235명을 대상으로 하였다. 퇴원 후 외래 추적관찰 중에 재발이 없었던 A군(225명: 96%), 재발이 있었던 B군(10명: 4%)으로 나누어서 후향적 조사를 통하여 재발 위험인자에 대하여 알고자 하였다. 결과: 각 군의 평균나이는 재발되는 군에서 $19.6{\pm}7.17$세로 더 어렸으며(p<0.05), 각군 남녀 비는 남자가 많았으나, 통계학적 의의는 없었다 흡연력, 병변 부위 및 폐허탈 정도는 양군사이에 유의한 차이는 없었다. 수술적 요인에 대한 것으로 술 후 공기 누출기간이 길수록, 흉관 거치 기간이 짧을수록 재발 가능성이 더 높았으며(p<0.05), 평균 재발기간은 $10.2{\pm}8.5$개월($0.6{\sim}22$개월)이었다. 재발된 군 중 4명은 술 후 한달 동안 충분한 준비 운동 없는 과격한 운동(농구 등)을 했던 경험이었다. 술 후 재발에 영향을 주는 단일 변수는 수술 시 나이,공기 누출기간, 키/몸무게 비 및 흉관 유지 기간이었으며, 다중 변수에 의한 위험 인자는 수술 시 나이, 신장/몸무게 비, 공기 누출 및 흉관 유지 기간 순이었다 결론: 자발성 기흉에서 흉강경을 이용한 폐기포 절제술은 재발율이 개흉술에 비하여 높지 않아서 시행할 수 있지만, 재발 위험인자로 나이가 젊거나, 큰 신장/몸무게비, 지속적인 공기 누출 있거나 짧은 흉관 유지 기간이었으며, 퇴원 후 너무나 빠른 심한 운동은 폐기포절제술 후 기흉 재발의 원인이 될 수 있다.

• Journal of Chest Surgery
• /
• 제26권6호
• /
• pp.475-482
• /
• 1993

90 patients[75 men and 15 women] with the thoracic disease underwent video-assisted thoracic surgery[VATS] during the period March 1992 to February 1993. The thoracic diseases were classified into two groups of spontaneous pneumothorax and general thoracic patients and they were 66 and 24, respectively.The mean size of the tumor resected was 4.3 $\pm$ 2.0 cm x 3.3 $\pm$ 1.1 cm x 2.7 $\pm$ 1.0 cm. The mean time of anesthesia and operation were 90.0 $\pm$ 19.9 min and 43.7 $\pm$ 13.1 min in spontaneous pneumothorax group and 123.3 $\pm$ 40.3 min and 62.8 $\pm$ 32.2 min in general thoracic group. The mean period of postoperative chest tube drainage and hospital stay were 5.0$\pm$ 5.5 days and 6.6 $\pm$ 7.4 days in spontaneous pneumothorax group and 3.5$\pm$ 1.6 days and 9.5 $\pm$ 6.1 days in general thoracic group. The indications of VATS were 71 pleural disease[78.9%: 66 spontaneous pneumothorax; 3 pleural effusions ; 1 pleural paragonimus westermanii cyst; 1 malignant pleural tumor with metastasis to the lung], 9 mediastinal disease[10.0%: 5 benign neurogenic tumor; 2 pericardial cyst; 1 benign cystic teratoma; 1 undifferentiated carcinoma], 8 pulmonary parenchymal disease[8.9%: 3 infectious disease ; 3 interstitial disease ; 2 malignant tumor ], and 2 traumatic cases of exploration and removal of hematoma[2.2%]. The applicated objectives of VATS were diagnostic[ 7 ], therapeutic[ 67 ] and both[ 16 ] and the performed procedures were pleurodesis[ 66 ], wedge resection of lung[ 59 ], parietal pleurectomy[ 11 ], removal of benign tumor[ 9 ], excision and/or biopsy of tumor[ 4 ], pleural biopsy and aspiration of pleural fluid[ 3 ] and exploration of hemothorax and removal of hematoma in traumatic 2 patients. The complication rate was 24.2%[ 16/66 ] in the spontaneous pneumothorax group and 8.3%[ 2/24 ] in the general thoracic group and so overally 20.0%[ 18/90 ]. The mortality within postoperative 30 days was 2.2%[ 2/90 ], including 1 acute renal failure and 1 respiratory failure due to rapid progression of pneumonia. The conversion rate to open thoracotomy during VATS was 5.6%[ 5/90 ], including 2 immediate postoperative massive air leakage, 1 giant bullae, 1 malignant pleural tumor with metastasis to lung and 1 pulmonary malignancy. The successful cure rate of VATS was 75.8%[ 50/66 ] in the spontaneous pneumothorax group and 76.5%[ 13/17 ] in the general thoracic group and the successful diagnostic rate was 100%[ 7/7 ]. In conclusion, although prospective trials should be progressed to define the precise role of VATS, the VATS carries a low morbidity and mortality and high diagnostic and therapeutic success rate and now can be effectively applicated to the surgical treatment of the extensive thoracic disease.