• 대한방사선기술학회지:방사선기술과학
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• 제38권3호
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• pp.229-235
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• 2015

유방확대수술이 미용을 위한 성형뿐만 아니라 유방암 절제술 후 재건의 목적으로 받는 등의 증가 추세이다. 유방확대수술을 받은 여성은 유방에 삽입한 보형물이 유방실질을 가려 유방질환을 진단하기 어려운 경우가 점점 증가하고 있고, 압박대로인한 보형물 파열 우려로 환자의 두려움은 증가하고 있다. 그러므로 유방보형물 삽입 여성에게 적용 가능한 압박대를 개발하여 그 유용성을 알아보고자 하며, 기존의 압박대와 새롭게 개발한 압박대를 유방보형물 삽입 환자모형의 phantom에 적용시켜 영상을 얻은 후 유방의 Inner, Outer 부분과 유두후방길이(Posterior Nipple Line; PNL), 전체적인 포함면적을 비교하여 그 유용성을 비교해보고자 한다. 개발한 압박대로 압박 시 전체 면적은 CC view에서 $9,813.797mm^2$로 10.09% 증가하였고, CC-ID view에서 $7,621.531mm^2$로 3.88% 증가하였으며, PNL은 CC view에서 90.916mm로 3.41% 증가, CC-ID view에서 75.357mm로 1.64% 증가하였다. 또한 흉벽 측 유방조직은 CC view에서 177.725mm로 3.53% 증가하였고, CC-ID view에서 152.510mm로 6.57% 증가되는 것으로 나타났으며, 기존의 압박대에 비해 개발한 압박대의 CC-ID 영상에서는 보형물이 완전히 제거된 것을 확인할 수 있었다.

• Archives of Plastic Surgery
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• 제37권5호
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• pp.695-698
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• 2010

Purpose: Supernumerary nipple or polythelia is one of the developmental anomalies occurring at the embryonic stage and this anomaly usually arises from the milk line. While this atypical feature is determined during early developmental stage, it may not come out obviously or become troublesome until puberty or lactation. Moreover, sometimes it is confused with a pigmented nevus. Methods: Case 1, a 18-year-old woman with intramammary supernumerary breast consisted of another nipple with middle sized areola on the right lower breast was admitted for a $2.8{\times}3.1\;cm$-sized mass on the right breast which was starting appeared 1 year earlier. The preliminary cytological examination of the material obtained by needle aspiration biopsy from the mass was revealed by fibroadenoma with no malignant change. The patient had the surgical excision of the mass and accessory breast. Case 2, a 16 year-old woman admitted for intra-areolar polythelia of the left breast, even she doesn't have any family history of polythelia. Since she wanted surgical correction of her atypical nipple for aesthetic and psychological reasons, we reconstructed the areola using transposition flaps in an S-plasty design. Results: Case 1, the excised supernumerary nipple showed following histological features. In the superficial layer, an acanthotic and hyperpigmented epithelium with elongated rete ridges was found. In the dermis, there were follicles with hairs surrounded by hypertrophic sebaceous glands. In the deepest portion, abundant secretory glomerules and excretory ducts of apocrine gland type were observed. Case 2, follow-up visits 3 months after the procedure showed a satisfactory result with good shape and projection of the nipple. Conclusion: We report two cases of aberrant mammary tissue who underwent surgical correction, including complete breast (with nipple, areola, and glandular tissue) and intra-areolar polythelia according to the Kajava's classification, and the results were satisfactory.

• 한국식품영양과학회지
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• 제44권11호
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• pp.1693-1699
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• 2015

본 연구에서는 국내에서 유통되는 각기 다른 브랜드 6종의 닭 가슴살 제품에 대해 이화학 검사, 조직감 검사 및 관능평가를 통하여 품질 비교 평가를 수행하였다. 평가 결과 일반 성분에서는 큰 차이가 없었으나, pH, 색상, 조리손실률에서 제품 간 큰 편차가 나타났다. 특히 연도 측정에서는 연도가 높은 제품군(A, B, C, D)과 연도가 낮은 제품군(E, F)으로 구분이 되어 제품의 숙성기간 또는 제품군별 냉동 방식에 따라 연도가 영향을 받음을 알 수 있었다. 묘사분석 결과 저작경도와 저작응집성에서 제품 간 유의적인 차이가 나타났고 두 특성 모두 F 제품에서 가장 높은 강도를 보였다. 소비자 기호도 조사 결과 연도 및 수분감이 가장 낮은 제품에서 기호도가 가장 낮게 나타나 연도 특성이 닭 가슴살의 품질을 결정하는 가장 중요한 지표 중 하나라는 것이 밝혀졌다. 본 연구에 사용된 닭 가슴살 제품은 제품별 사육부터 가공, 유통과정에 있어서 여러 가지 다양한 변수가 존재하고 이에 대한 정보가 공개되지 않았으므로 제품 품질 차이에 영향을 주는 인자들을 정확하게 독립적으로 구분하기는 불가능하나 현재 국내에 시판 유통되는 닭 가슴살 제품의 품질 간 큰 차이가 존재하고 소비자들의 기호도에 영향을 미치는 요인들을 밝혀냄으로써 국내 가금육 제조업체들이 소비자들의 기호도가 최적화된 닭 가슴살 제품을 생산 및 관리하는 데 본 연구 결과를 유용하게 사용할 수 있을 것으로 판단된다.

• Journal of Nutrition and Health
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• 제57권1호
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• pp.43-52
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• 2024

본 연구에서는 석류 유래 나노베지클이 유방암 세포인 MDA-MB-231 세포에 항 혈관 신생효과와 세포 증식을 억제하는지 확인하고자 하였다. 석류 주스로부터 분리한 석류 유래 나노베지클(PNVs)이 평균 직경이 162 nm의 이중막 구조인 나노베지클을 검증하였다. MDA-MB-231 세포에 석류 유래 나노베지클의 내재화를 확인하였다. 석류 유래 나노베지클이 MDA-MB-231 세포에 농도 의존적으로 세포 증식률을 감소시키는 것을 확인하였다. 또한, 석류 유래 나노베지클이 MDA-MB-231 세포에 침윤 및 전이를 억제하는 것을 확인하였다. 마지막으로 세포 발현 단백질을 증가시키고 MMP-2, MMP-9 단백질의 발현을 감소시키는 것을 검증하였다. 본 연구는 석류 유래 나노베지클이 인간 유방암 세포인 MDA-MB-231 세포의 세포 침윤 및 전이를 억제하고 세포사멸을 시켜 항암효과가 있음을 제시하고 있다. 따라서 석류 유래 나노베지클이 유방암 예방 및 치료에 이용 가능함으로 시사된다.

• 동아시아식생활학회지
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• 제21권1호
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• pp.24-30
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• 2011

The anti-cancer effects of Angelica keiskei ethanol extract were evaluated in human breast cancer MDA-MB-231 cells. The concentrations of extract were 1, 2, 3, 4 and 5 mg/mL. Dose-dependent reductions in the number of cells with altered cell shape and pyknotic nuclei were observed at 48 h after treatments. MTT assay also exhibited a similar dose-dependent reduction in mitochondrial reductase activity (p<0.05), in particular, with a rapid reduction in the activity of the 5 mg/mL group. Analysis of cell death with propidium iodide (PI) staining revealed only a slight increase in cell death in the 5 mg/mL group. Analysis of bromodeoxyuridine (BrdU) incorporations also showed a dose-dependent reduction in cell proliferation (p<0.05). Finally, increases in total radical oxygen species (ROS) accumulation in cells, as revealed by DCF-DA staining, were observed in the treated groups in a similar dose-dependent fashion (p<0.05). These results indicate that Angelica keiskei ethanol extract exhibiting anti-cancer effects in MDA-MB-231 cells causes multiple changes in cell shape, enzyme activity, and ROS accumulation, thereby inducing cell death.

• 복식
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• 제6권
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• pp.105-119
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• 1982

This thesis is mainly about the changes of Garment's collar(옷깃) and outer collar (옷섶) which indicate the identification of dress history. Through the observations of some reports about important folk materials and genuine objects, the author has investigated and rearranged them focusing on Yi-Dynasty. (1400-1900) For the shape of the outer lapels(겉깃) of Korean Jacket(저고리) were used together Squar-Tray-Collar(목판깃), Sharped-Collar(칼깃), and Dang ko-Collar(당코깃) and coming to the end of inner lapels(안깃) formed squar-tray-collar. Squar-tray-collar and sharped-collar were mainly used together for the shape of the outer lapels of Korean overcoat(포). Dang ko-collar was seen only in two overcoat. Coming to the 18th centry, the outer lapels became round-edged like those of jackets, while the inner lapels formed squar-tray-collar. In the process of positional changes of the collar and outer collar of Korean jacket and overcoat, the outer lapels positioned outside the outer collar, or a part of width of collar's positioned upon the outer collar, or the whole outer lapels positioned inside the outer collar. And through these changes the current position of the outer lapels became settled in the end of the 19th centry. But the inner lapels did not undergo many changes compared with the outer ones, and their position was mainly outside the outer collar like those of current lapels. And the garment's collar and outer collar of jacket and overcoat became small while the width and length of breast-tie(고름) became large.

• 대한영상의학회지
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• 제84권2호
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• pp.398-408
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• 2023

목적 유방의 양성 선근상피종의 영상 소견에 대해 기술하고자 한다. 대상과 방법 최근 20년 동안, 본원에서 조직 확진된 120명의 환자의 유방에서의 선근상피종을 대상으로 하였다. 43명의 환자는 유방암으로 유방 전 절제술을 시행하면서 우연히 발견되어 제외하였으며, 28명의 환자는 절제생검을 하지 않고 경피적 생검만 시행하여 제외하였고, 8명의 환자는 생검에서 양성 선근상피종으로 확인되었으나 완전 절제술 후 다른 질환으로 확진되어 제외하였다. 결과적으로, 완전 절제술 후 조직 확진된 41명 환자의 양성 선근상피종에 대해 후향적으로 임상 정보와 영상 소견을 분석하였다. 결과 유방촬영술에서 병변은 원형 또는 타원형의 모양(56%), 경계가 좋지 않음(62%), 고밀도음영(53%), 종괴형(89%)을 보였으며, 미세석회회가 없었다(95%). 유방초음파에서 병변은 의심스러운 종괴(98%), 경계가 좋지 않음(66%), 저에코(43%), 그리고 종양내 혈관성(63%)을 보였다. 유방자기공명영상에서 의심스러운 종괴(100%), 불분명한 경계(61%) 그리고 조영증강 시 지연기 소실(84%)을 보였다. 양성 선근상피종의 41개 병변 중 16개 병변은 처음 중심바늘생검에서 다른 질환으로 오진되었으며 2명의 환자는 유방암으로 오진되었다. 결론 유방의 양성 선근상피종은 유방촬영술, 유방초음파, 유방자기공명영상에서 악성 종양과 유사한 의심스러운 특징을 보인다. 양성 선근상피종을 다른 질환과 감별하는 것은 중심바늘생검만으로는 어려우며, 올바른 진단을 위해서는 완전절제술이 필요하다.

• 한국생활과학회지
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• 제7권1호
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• pp.147-165
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• 1998

The object of this study was to help designing of well-fit and comfortable brassieres for the elementary school girls through the survey on actual condition of wearing brassieres. The subjects of investigation for this study was the elementary school girls in the province of Jeonbuk and Taejeon city. The conclusion of this study was as follows; The 40.2% of the total subjects were wearing brassieres like the 63.3% of the fourth, the 85.4% of the fifth, and the 89.7% of the sixth grade students. The main reason of non wearing brassieres was for the underdeveloped breast, and also that of wearing brassieres was for the good shape of the breast. The main types of brassieres were ranked "Tank Top type", "Mold type", and "Adolescent girl-Bra". They had started to wear brassieres by the recommendation of adults who were their mother or teachers, and usually wearing brassieres all day. They usually purchased brassieres "with mother together" or "only by their mother". The standard of choosing brassieres was also ranked by FASHION, CONVENIENCE, SIZE, TOUCH, and SWEAT ABSORPTION. The total score of satisfaction for wearing brassieres was showed "Average score" and the score higher in Jeonju and Taejeon than in Kunsan. The higher grade and fatter was showed decreasing the score of satisfaction. The higher grade became, the more various for the size and preferable a pure cotton fabric for brassieres. The favorite types of brassieres were "Sport Bra" and "Volume-up Bra". They usually purchased a little larger size than their original size of that.

• Advances in nano research
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• 제6권2호
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• pp.183-200
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• 2018

In the present study silver nanoparticles (AgNPs) were successfully synthesized using aqueous extract of Sargassum muticum. The aqueous extract (10%) treated with 1 mM silver nitrate solution resulted in the formation of AgNPs and the surface plasmon resonance (SPR) of the formed AgNPs was recorded at 360 nm using UV-Visible spectrophotometer. The molecules involved in the formation of AgNPs were identified by Fourier transform infrared spectroscopy (FT-IR), surface morphology was studied by using scanning electron microscopy (SEM), SEM micrograph clearly revealed the size of the AgNPs was in the range of 40-65 nm with spherical, hexagonal in shape and poly-dispersed nature, and X-ray diffraction spectroscopy (XRD) was used to determine the crystalline structure. High positive Zeta potential (36.5 mV) of formed AgNPs indicates the stability and XRD pattern revealed the crystal structure of the AgNPs by showing the Bragg's peaks corresponding to (111), (200), (311) and (222) planes of face-centered cubic crystal phase of silver. The synthesized AgNPs exhibited effective anticancerous activity (at doses 25 and $50{\mu}g/ml$ of AgNPs) against Breast cancer cell line (MCF7).

• 대한가정학회지
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• 제46권2호
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• pp.127-135
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• 2008

The study purpose was to increase Han-bok's convenience by changing materials while maintaining keep the traditional Han-bok style. For this purpose we surveyed actual Han-Bok wearers about the inconveniences of its form and design by combining knit with Han-bok. On the basis of this survey, we present a practical design for use in daily fife. Responding to the question about Jeo-Go-Ri(jacket), most respondents preferred a Han-bok which stressed elasticity by utilizing knit on Jeo-Go-Ri's front and back body line(JD1, JD4). For the question about ann holes, most respondents liked a design which substituted knit materials for Sam-hoi-jang(colorful strips) to ensure ease of use and shorten both the width and length of the breast-tie(JD2, JD3). For the sleeve edge, they preferred a design which solved the difficulties of rolling up the sleeve when working ($JD2{\sim}JD5$). Regarding the most inconvenient aspect of wearing Chi-mas(skirts), the respondents indicated tightening of the breast and an uncomfortable feeling due to the skirt length. This suggested that the waist of the vest should be lengthened to avoid the feeling of pressure(CD2, CD5). Regarding changes to the skirt shape the respondents preferred buttons and hooks rather than using skirt strings(CD4, CD5).