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A CASE OF AGGRESSIVE FIBROMATOSIS INVADED MANDIBULAR BODY ON THE PAROTID REGION (이하부에 발생한 침습성 섬유종증이 하악체에 침범한 증례 보고)

  • Kim, Young-Jo;Lee, Dong-Keun;Um, In-Woong;Min, Seung-Ki;Chung, Chang-Joo;Kim, Eun-Cheol
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.16 no.2
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    • pp.186-195
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    • 1994
  • Fibromatosis is benign fibroblastic proliferative lesion with abundant collagenous neo-formation located principally in the abdominal wall and in the upper and lower extremities (Masson & Soule, 1966). Wilkins and Waldron, in 1975, suggested that the title aggressive fibromatosis was a more appropriate term, reflecting the invasive characteristics of the disease. Synonyms listed were extra-abdominal desmoid, juvenile fibromatosis, aggressive infantile fibromatosis and congenital fibrosarcoma. A total of 12% of all fibromatosis arise in head and neck. Fibromatosis of the oral cavity is uncommon and is even more rare when in involve the mandibule. It is a locally aggressive fibrous tissue tumor, generally does not metastasize, but may cause considerable morbility and even death due to local infiltration. The degree of microscopic cellularity is variable, not only from tumor to tumor but also from area to area in the same tumor. Some tumors present with proliferation of mature fibroblasts and a dominating collagenous component : others may show a lack of the tumor in both types. The common histologic denominator appears to be cellular interlacing bundles of elongated fibroblasts, showing little or no mitotic activity and no pleomorphism. Mitosis are not a consistent index of malignancy when found in younger age groups. Fibromatosis still posses difficult problems of diagnosis and treatment. It is frequently recurrent and infliltrates neighbouring tissues. These lesion infliltrate widely and replace muscle, fat, and even bone with fibrous tissue of varying cellularity. Lesion representing fibromatosis in the oral cavity must be carefully evaulated by both surgeon and pathologists to ensure proper diagnosis and treatment planning. When these lesions involve bone, surgeon must be aware of the lesion's potential to perforate the cortex and expand while remaining hidden from the surgeon's view. Careful and precise clinical correlation with histologic appearance is essential to preclude misdiagnosis of fibrosarcoma yet provide surgical treatment plan that provides adequate local excision and long-term follow up. As regards cause, little is known. It is attributed to trauma or alteration in the sex hormone(Carlos, et al, 1986). Clinially, the lesion is reported to be not painful in most cases, but capable of rapid growth. The treatment is essentially surgical excision with wide margin of adjacent uninvolved tissue. Radiotherapy, hormone treatment or chemotherapy are of no use (WIkins et al, 1975 ; Majumudar and Winiarkl, 1978). We report a case of aggressive fibromatosis of 15-year-old with a lesion in the soft tissue of the parotid area that invaded the underlying bone of the mandibular body.

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Thermal Insulation Effect of Inflatable Life Vest on the Drowned Individual estimated by Numerical Analysis (익수자 체온 저하에 미치는 팽창식 구명동의의 단열효과 수치 분석)

  • Kim, Sung Chan;Lee, Kyung Hoon;Hwang, Se Yun;Lee, Jin Sung;Lee, Jang Hyun
    • Journal of Navigation and Port Research
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    • v.39 no.4
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    • pp.285-291
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    • 2015
  • Exposure to cold sea water can be life-threatening to the drowned individual. Although appropriate life jacket can be usually be provided for the buoyance at the drowning accident, heat loss can make the drowned individual experience the hypothermia. Inflatable life jackets filled with inflatable air pocket can increase the thermal protection as well as the buoyancy force. Because it is important to know how the human body behaves unde the different life jacket, present study compares the thermal insulation capacity of solid type life jacket with that of inflatable life jacket. In order to represent the insulation capacity of life jacket, thermal resistance is estimated based on the assumption of steady-state. Also, a transient three-dimensional thermal distribution of the thigh is analyzed by using finite element method implementing the Pennes bioheat equation. The finite element model is a segmental, multi-layered representation of the body section which considers the heat conduction within tissue, bone, fat and local blood flow rate.

Assessment of Isokinetic Muscle Function in Elite Canadian College Paddlers (대학 엘리트 카나디언 선수들의 어깨·허리·무릎 관절의 등속성 근기능 평가 및 진단)

  • Shin, Kwang-Taek;An, Chang-Gyu;Sohn, Jee-Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.1
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    • pp.229-238
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    • 2013
  • The aim of this study is to evaluate university canadian paddlers' iso-kinetic muscle function and provide training advices. Eight university paddlers with a 8.5 years career participated in this study. Inbody 720, biodex system III, biodex stabilizer system and THP 2 are used to investigate body component, muscle function(peak torque, average power and work fatigue), agility and dynamic balance. Iso-kinetic muscle function around shoulder, thorax and knee are measured. And then bilateral and unilateral muscle imbalance are calculated at each joint. Results of this study are as follows; University canadian paddlers' BMI average is 24.90 $kg/m^2$ and percent body fat is 12.23%. Reaction time average was 324 msec and balance score at each leg are below 2.0. A3, A4, A5, A6, A8 are needed to train shoulder muscle strength and power. A1, A2, A7, A8 are needed to strengthen shoulder muscle endurance. A2, A5, A8 are needed to train thorax muscle strength and power. A1, A8 are needed to strengthen thorax muscle endurance. Most of paddlers' reciprocal muscle balance ratio on thorax and knee are out of normal range. A2, A3, A4, A8 are needed to train abdominal strength and A3, A5, A6, A7, A8 are needed to train hamstring strength.

The Study on Risk Factor of Metabolic Diseases in Pancreatic Steatosis (췌장지방증에서 대사성질환의 위험 요인에 관한 연구)

  • Cho, Jin-Young;Ye, Soo-Young;Kim, Dong-Hyun
    • Journal of radiological science and technology
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    • v.39 no.1
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    • pp.81-88
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    • 2016
  • The body of the fat tissue increased in obese represented by risk factors such as cardiovascular diseases, diabetes, metabolic disease and dyslipidemia. Such metabolic diseases and the like of the cardiovascular and cerebrovascular disease, hypertension, dyslipidemia, increase in the adipose tissue of the pancreas is known to be a risk factor of these diseases. Study on the diagnosis and treatment of pancreatic cancer was conducted actively, case studies on pancreatic steatosis is not much. In this study, divided into a control group diagnosed with pancreatic steatosis as a result of ultrasonography to evaluation the physical characteristics and serologic tests and blood pressure and arterial stiffness. The control group and the test pancreas steatosis age and waist circumference, body mass index, total cholesterol, HDL cholesterol, LDL cholesterol, and systolic and diastolic blood pressure, fasting blood glucose, arterial elasticity is higher in pancreatic steatosis. And the lower ankle brachial stenosis and HDL-cholesterol were lower than the normal control group, so the pancreatic steatosis harmful to blood vessels.(P <0.05). The difference between the control group and it was confirmed that the pancreatic jibanggun statistically significant. In conclusion, pancreatic steatosis at abdominal ultrasound can predict the risk of metabolic diseases, and there was a correlation with cardiovascular disease.

Effects of Feeding Mixture of Commercial Broiler Feed with Spent Bleaching Clay from Vegetable Oil Refinery on Broiler Performance (육계사료와 식용유 정제 폐백토(Spent Bleaching Clay) 급여가 육계의 생산성에 미치는 영향)

  • Jeon H. Y.;Son J. H.;Lee K. W.;Kim S. K.;Kang H. S.;Shin T. S.;Cho B. W.
    • Korean Journal of Poultry Science
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    • v.32 no.4
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    • pp.255-260
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    • 2005
  • This study was conducted to evaluate the feasibility of spent bleaching clay(SBC) as an energy resource for meat type chicks. A total of one hundred twenty 1-d old broiler chicks(Han-hyop, No. 3) were divided into four groups and each group was assigned to one of the following diets: 0(T1), 2.0(T2), 4.0(T3) and $6.0\%$ SBC(T4). Each treatment had 3 replications of 10 birds. Before feeding experimental diets, they were fed a commercial diet for a week Body weight gain and feed intake tended to increase in T3 and T4, respectively. Feed efficiency(feed intake/ gain) tended to decrease in T3 compared to other groups. Fatty acid composition of breast and thigh meat was not significantly affected by feeding SBC. Utilization of dry matter, energy, crude protein and crude fat was lower in T4 than in the other groups during both starter and finisher periods(p<0.05). Crude ash utilization was not significantly affected by feeding dietary SBC. These results indicate that broiler diets may be supplemented with 2 to $4\%$ SBC without adverse effect on growth.

A Computerized System for Diagnosis and Nutritional Assessment of Dietary Intakes : Recommended Dietary Allowances for Koreans, 6th Revision (식이섭취의 진단 및 영양평가를 위한 전산시스템 : 제6차 한국인 영양권장량에 준함)

  • 한지숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.4
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    • pp.726-732
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    • 1997
  • The purpose of this study is to develop a software program to diagnose and assess status of dietary intake obtained using 24-hour dietary recall method. This program consist of four functions. The first function is assessing tile general status of the body such as ideal body weight, obesity measure, activity expenditure energy and total energy requirement by the analysis of age, height, weight and the degree of activity. The second one is calculating the intake number of food classified by the food group and evaluating the status of food intake by comparing them with the number of standardized intake in recommended dietary allowances for Koreans,6th revision. Third one is calculating energy and nutrient intakes contributed by the food group in dietary intake and evaluating the status of dietary intake by comparing the nutrient intake with the recommended dietary allowance for Korean, especially calculating and evaluating the status of dietary fat intake. The fourth function is calculating and evaluating the status of nutrient intake and nutrients energy Percent contributed by three regular meals and at least one in-between-meal snack. The results are displayed as tabular forms and graphical forms on the computer screen.

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Effect of stocking density and alpha-lipoic acid on the growth performance, physiological and oxidative stress and immune response of broilers

  • Li, Wenjia;Wei, Fengxian;Xu, Bin;Sun, Quanyou;Deng, Wen;Ma, Huihui;Bai, Jie;Li, Shaoyu
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.12
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    • pp.1914-1922
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    • 2019
  • Objective: The study was conducted to evaluate the effect of stocking density and alphalipoic acid (ALA) on the growth performance, feed utilization, carcass traits, antioxidative ability and immune response of broilers. Methods: A total of 1,530 22-day-old male broilers (Arbor Acres) with comparable body weights ($731.92{\pm}5.26$) were placed into 18 cages ($2.46{\times}2.02m$) in groups of 75 birds ($15birds/m^2$, $37.5kg/m^2$; low stocking density [LD]), 90 birds ($18birds/m^2$, $45.0kg/m^2$; high stocking density [HD]) and 90 birds with 300 mg/kg ALA added to the basal diet ($18birds/m^2$, $45.0kg/m^2$; HD+ALA, high stocking density+${\alpha}$-lipoic acid); each treatment was represented by 6 replicates. The experimental period was 3 weeks. Results: The results showed that the high stocking density regimen resulted in a decreased growth, feed conversion ratio, carcass weight, thigh yield and bursa weight relative to body weight (p<0.05) on d 42. The abdominal fat yield in the HD+ALA group was lower (p = 0.031) than that of the LD group at 42 d. The superoxide dismutase and glutathione peroxidase activities in serum were increased, and malondialdehyde content decreased after adding ALA product (p<0.05) on d 42. Additionally, the serum concentrations of immunoglobulin A (IgA) and IgG were decreased (p<0.05) and the level of diamine oxidase was higher (p<0.01) in the HD group on d 42. Conclusion: The high stocking density significantly decreased broiler growth performance, feed utilization and carcass traits, increased physiological and oxidative stress and induced intestinal mucosal injury. The supplementation of ALA product in broiler diet at 300 mg/kg may reduce the adverse effects of high stocking density-mediated stress by maintaining the antioxidant system and humoral immune system.

Effects of ${\beta}2-Adrenergic$ Receptor Polymorphism on Obesity (베타 2-아드레날린 수용체의 유전자 변이형이 비만도에 미치는 영향)

  • Kim, Kil-Soo;Oh, Hyun-Hee;Choi, Sun-Mi;Yang, Hyun-Sung;Bae, Jung-Hwan;Yoon, Yoo-Sik
    • Journal of Korean Medicine for Obesity Research
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    • v.3 no.1
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    • pp.7-16
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    • 2003
  • Objectives : The lipolytic effects of catecholamines in adipose tissue are mediated by members of adrenergic receptors. This study was conducted to examine the effects of ${\beta}2-AR$ Gln27Glu (Q27E) polymorphism on obesity indices and risk among obesity clinic patients. Methods : 532 subjects, 38 men and 494 women, who attended a weight loss program in a local obesity clinic were analyzed. Height, weight, BMI, WHR and obesity index were measured or calculated. Body composition was measured by bio-impedance analysis. Genotype of ${\beta}2-AR$ polymorphism in codon 27 was analyzed by PCR-RFLP method. Serum concentrations of fasting glucose, total and HDL cholesterol, and triglyceride were determined by autobiochemical analyzer. Results: The Genotype distributions of ${\beta}2-AR$ gene were QQ type 81.3%, QE type 17.9% and EE type 8%. Therefore, the frequency of E allele of ${\beta}2-AR$ gene was 0.170 in the total subjects. The frequency of the ${\beta}2-AR$ variant genotype(QE+EE) was significantly higher in obese group($BMI{\geqq}25$) compared with non-obese group(p=0.027). Weight was significantly higher in variant(QE+EE) type compared with normal(QQ) type in total subjects(p=0.001), male(p=0.022) and female(p=0.013). BMI, obesity index and WHR were also significantly higher in QE+EE type. Body fat man was significantly higher in QE+EE type in total subjects(p=0.005) and female(p=0.027). When forward stepwise regression analysis was used to create a model of risk predictors of obesity($BMI{\geqq}25$), QE+EE type of ${\beta}2-AR$ gene was found to be a significant risk factor for obesity (p=0.042, ORs 1.597). Conclusions: QE+EE genotype of ${\beta}2-AR$ was associated with increased obesity indices and might be a significant risk factor for obesity.

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An Analysis of Domestic Medicine Study Tendency on Obesity -Focused on The Korean Journal of Obesity- (비만에 대한 국내 의학계의 최근 연구 동향 분석 -대한비만학회지를 중심으로-)

  • Kim, Doo Hee;Shin, Woo Suk;Kim, Dong Hwan;Jeong, Yeon Jae;Im, Han Bit;Park, Won Hyung;Cha, Yun Yeop
    • Journal of Korean Medicine for Obesity Research
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    • v.13 no.1
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    • pp.1-9
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    • 2013
  • Objectives: This study was performed to analyze the recent trend of the studies about obesity in medicine and to provide background for futher studies. Methods: All of the article were selected in "The Korean Journal of Obesity". Search were conducted through "http://kosso.or.kr" with the search word "obesity". Collected articles were classified into clinical study, experimental study, literary study, case report. Results: One hundred eighty four studies were included and analyzed in terms of study design, subject, intervention, period, obesity index and so on. The numbers of clinical studies, literary studies, experimental studies, case reports were respectively 143 (77.7%), 26 (14.1%), 2 (1.1%) and 7 (3.8%). In clinical studies, observational studies were 112 (78.3%) and intervention studies were 31 (21.7%). And most of sample sizes were more than 100 and less than 499. Body mass index, waist circumstance, body fat percent were major criteria of clinical study. Most of the subjects on obesity were about relation with another disease or experimental results and diagnosis. According to classification by the kinds of intervention, diet, exercise, drug, behavior were respectively 22, 18, 8, and 8. More than fourty percent of intervention studies were studied for 12 weeks. Conclusions: To improve the quality of Korean Medicine study for obesity, we need to recruiting big sample size and activate randomized clinical trial.

Changes in the girth of anthropometric variables during menstrual cycle in women university students (여자대학생의 생리주기에 따른 인체계측변인 둘레의 변화)

  • Kim, Young-Sun;Kang, Seol-Hee;Kim, Yun-Jung;Park, Won-Yeop;Jang, Jee-Hun
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.14 no.5
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    • pp.421-429
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    • 2021
  • The purpose of this study was to identify the change in the girth of anthropometric variables during menstrual cycle, and to provide basal data for health promotion program development during pre-menstrual phase and menstrual phase. Participants were 10 healthy women university students without menstrual irregularity, subjective premenstrual syndrome, premenstrual dysphoric disorder, dymenorrhea, obstetrician and gynecologic disease. Chest girth(axillary and papillary), waist girth(half point between iliac crest and 12th rib, and navel), and hip girth were repeatedly measured in menstrual phase, follicular phase, luteal phase during single menstrual cycle. As a result, axillary chest girth in menstrual phase was significantly increased than that in luteal phase. Papillary chest girth and waist girth at half point between iliac crest and 12th rib in menstrual phase were significantly increased than those in follicular phase. No significance was shown in chest and waist girth between follicular and luteal phase. No significance was shown in hip girth during menstrual cycle. In conclusion, signicant difference was shown in chest and waist girth during menstrual cycle. And it is suggested that succeeding research should be carried out with reference to body weight, body fat, blood and local hormone concentration during menstrual cycle.