• Journal of mucopolysaccharidosis and rare diseases
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• 제1권2호
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• pp.49-53
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• 2015

Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder characterized by hypothalamic-pituitary dysfunction. Many features of PWS indicate a deficiency in growth hormone (GH) production, and these findings provide a rationale for GH therapy in PWS. It is possible that rhGH therapy could have beneficial effects in adults with PWS, similar to those in adults with GH deficiency (GHD) of non-syndromic cause. However, there is a paucity of data on the use of GH in adults with PWS. Here, the previous studies about efficacy and safety of rhGH therapy in PWS adults are summarized. Briefly, rhGH therapy in PWS adults may improve body composition, leading to increased lean body mass and decreased fat mass, as well as decreased subcutaneous and visceral adiposity without overall changes in body mass index. There may be at least transient deterioration in glucose homoeostasis in some PWS patients on rhGH therapy, which requires further study. In addition, clinical care guidelines for rhGH therapy in adults with PWS were suggested.

• 한국양식학회지
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• 제7권2호
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• pp.109-122
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• 1994

천연 및 인공 넙치 종묘의 성장 단계에 따른 체지질 조성 변화를 비교 검토한 결과는 다음과 같다. 1) 어체의 지질 및 비타민 E 함량은 천연 종묘 보다 인공 종묘에서 높은 값을 나타내었다. 2) 어체 성장에 따른 지질, 지방산(18: 2n-6, 22: 6n-3) 및 비타민 E 함량 변화는 부화 후 전장 5-10mm 전후의 배합 사료 공급기에서 급격한 증감 현상을 보였다. 3) 어체 지질, 지방산 조성 및 비타민 E 함량은 먹이 조성에 직접적인 영향을 받았다. 4) 천연 종묘는 인공 종묘에 비해 자연 상태에서 지질 함량이 낮고 고농도의 DHA를 함유하고 있는 천연 먹이를 섭취한 것으로 추정되었다.

• Journal of Animal Science and Technology
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• 제57권12호
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• pp.42.1-42.14
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• 2015

Background: Dietary fats can alter the deposition and distribution of body fats in ruminants. The deposition and distribution of body fat play a vital role in the quality of ruminant carcasses and are of great commercial value since they influence the profitability and consumer acceptability of ruminant meat. The current study examined the effects of dietary blend of 80 % canola oil and 20 % palm oil (BCPO) on carcass characteristics, meat yield and accretion of fatty acid (FA) in subcutaneous, omental, perirenal, and mesentery adipose depots and m. supraspinatus (SS) in goats. Methods: Twenty four Boer crossbred bucks (BW $20.54{\pm}0.47kg$) were randomly assigned to diets containing on DM basis 0, 4 and 8 % BCPO, fed for 100 d and harvested. Results: Diet had no effect (P > 0.05) on slaughter weight, dressing percentage, carcass and non-carcass components, meat yield, color, moisture and carotenoid contents and weight of adipose tissues in goats. The proportion of C18:1n-9 and cis-9 trans-11 CLA in the omental, perirenal and SS was higher (P < 0.05) in goats fed 4 and 8 % BCPO compared with the control goats. Dietary BCPO reduced (P < 0.05) the proportion of C14:0 in the omental, perirenal and mesentery depots, C18:0 in the perirenal depot, C16:0 in the SS and C16:1n-7 in the SS, omental and perirenal tissues. Dietary BCPO enhanced the proportion of C18:1 trans-11 Vaccenic and C18:3n-3 in SS and C20:5n-3 in SS and mesentery depot. No significant changes were found in the FA composition of subcutaneous depot. Conclusions: Results indicate that dietary BCPO can be utilized to alter the FA composition of adipose tissues without detrimental effects on carcass characteristics in goats. Nonetheless, dietary BCPO is not an effective repartitioning agent for body fats in goats.

• 한국컴퓨터정보학회논문지
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• 제26권4호
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• pp.133-142
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• 2021

본 연구의 목적은 여성노인을 대상으로 모던댄스, 아쿠아로빅, 복합운동 프로그램을 실시한 후 신체조성과 신체기능체력에 대한 변화 비교하여 여성노인에게 가장 적합한 운동이 무엇인지를 살펴보고자 실시되었다. 연구의 대상자는 J도에 거주하는 노인여성 47명을 대상으로 MDG(n=13) AEG(n=11), CEG(n=11), CG(n=12)을 무작위로 집단을 모집하여 12주간 주3회 1시간씩 운동을 실시하였다. 이 연구의 결과 통제그룹에 비해 grip strength, chair stand, arm curl, 2 minute step, 244cm up and go에서 유의한 차이를 보였으며, Back scratch는 MDG와 CEG에서만 운동 후 유의하게 감소하였으나 Chair sit and reach에서는 변화가 보이지 않았다. 본 연구결과 운동그룹 중 모던댄스(MDG)가 운동 후 가장 많은 신체기능체력이 향상된 것으로 나타났으며, 노인들에게 유연성과 관절의 가동성을 증진 시킬 수 있는 추가적인 운동프로그램이 필요하다. 또한 자신의 흥미에 맞는 운동을 자발적으로 참여하여 지속성 있게 하는 것이 중요할 것으로 생각된다.

• 운동영양학회지
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• 제23권2호
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• pp.34-44
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• 2019

[Purpose] The composition of protein supplements, the consumption timing immediately before and after resistance exercise training (RET), and the quantity of protein supplementation may be important factors for the im-provement of muscle mass and function. Although these factors should be considered comprehensively for effective improvement of muscular function in protein supplementation, relatively few studies have focused on this area. Therefore, this study was designed to investigate whether a protein blend supplement before and after resistance exercise for 12 weeks would be effective in increasing muscular function. [Methods] In total, 18 participants were randomly assigned to a placebo (PLA) or protein blend supplement (PRO) group. All subjects followed the same training routine 3 times per week for 12 weeks, taking placebo or protein supplements immediately before and after each exercise session. The protein supplement consisted of 40 g of blend protein, including hydrolyzed whey protein. The RET consisted of lower body (barbell squat, dead lift, seated leg extension, and lying leg curl) and upper body (bench press, barbell rowing, preacher bench biceps curl, and dumbbell shoulder press) exercises. A repetition was defined as three sets of 10-12 times with 80% of one repetition maximum (1RM). [Results] Although the PRO group had a lower protein intake in terms of total food intake than the PLA group, the mean changes in muscle circumference, strength, and exercise volume increased, especially at week 12, compared to the PLA group. [Conclusion] These results suggest that the composition and timing of protein intake are more important than the total amount.

• 한국지역사회생활과학회지
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• 제26권2호
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• pp.225-236
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• 2015

Materials for nutrition education to promote nutrition intake and prevent diseases in elderly individuals were developed, nutrition education was provided to 46 elderly females for 12 weeks, and its effects on the body composition, blood profile, and nutritional quality of subjects were qualitatively analyzed. After the education program, the weight of subjects decreased from 56.7 kg to 56.0 kg (p<0.001), their body fat dropped from 20.8 kg to 19.6 kg (p<0.01), their body mass index (BMI) declined from $25.2kg/m^2$ to $24.9kg/m^2$ (p<0.01), and their percentage of body fat decreased significantly (p<0.05). On the other hand, blood sugar showed a significant increase from 131.6 mg/dl to 141.8 mg/dl (p<0.05). Overall, the percentage of nutrition intake rose. In particular, the estimated energy requirement increased from 89.3% to 99.5% (p<0.05). Further, the contrast ratio of recommended intake showed significant increases in protein (p<0.01), phosphorus (p<0.05), vitamin $B_2$ (p<0.05), vitamin $B_6$ (p<0.05), and niacin(p<0.001), and that of adequate intake showed a significant increase in sodium (p<0.05). The nutrient adequacy ratio (NAR) showed a significant increase only in niacin (p<0.05), and the index of nutritional quality (INQ) showed significant increases in protein (p<0.05) and niacin (p<0.001). After the nutrition education program, a qualitative analysis of nutrients consumed by subjects was conducted. The results show improvements across the board except for the deficient intake of calcium and folic acid, suggesting that the nutrition status of subjects changed in a positive direction through the program. The implementation of this program for elderly individuals in a continuous and repetitive manner is expected to facilitate their nutrition management.

• Journal of Nutrition and Health
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• 제22권2호
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• pp.102-107
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• 1989

중년기 여성들에서 체중증가로 인한 여러 가지 건강문제가 심각해지는데 폐경으로 인한 sex steroid hormone의 변화에 기인되는 것으로 생각된다. Sex steroid hormone의 부족은 체중, 특히 체지방의 축적을 가져오고 한편 뼈의 손실을 가져온다고 알려져 있다. 본 연구에서는 폐경기 후의 여성들과 유사한 조건을 만들기 위해 성숙한 암쥐를 이용하여 난소절제를 한후 장기적인 체조성의 변화를 조사하였다. 난소절제한 쥐들은 체중과 체지방의 무게가 유의적으로 증가한데 반하여 근육과 뼈의 무게는 대조군과 비교할 때 커다란 변화가 없었다. 이 연구결과는 폐경기 여성들에게 일어나는 체조성 변화에 미치는 sex steroid hormone의 영향을 조사하기 위한 실용적인 animal model로 난소절제한 쥐의 사용가능성을 암시해 주고 있다.

• 한국양식학회지
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• 제21권4호
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• pp.278-284
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• 2008

인공종묘 생산된 감성돔 Acanthopagrus schlegeli 치어를 잘 피밭에 방류하여 방류초기의 먹이섭취와 체성분 변화에 대하여 조사하였다. 방류어의 먹이섭취율(predation rate)은 1일째와 3일째 79%로 낮았으며, 7일과 10일째 100%로 증가하였으나 20일째와 30일에는 75%로 낮아졌다. 방류된 감성돔 치어는 단각류와 복족류(Gastropoda)를 주로 섭식하였다. 단각류(Amphipoda)의 섭취는 방류 초기와 30일째에 낮고, 15일째에 82.9%로 가장 높았다. 한편 복족류는 1일째 84.6%로 가장 높았으며, 20일째는 3.1%로 가장 낮은 값을 보였으며, 갑각류와 해조류는 채집 기간동안 20% 내외를 나타내었다. 소화기관 중량비는 방류 후 20일과 30일째 유의적으로 낮은 값을 보였다. 전어체 성분에서는 방류 후 시간 경과에 따라 조단백질과 조지방 성분이 유의적으로 감소하였으며, 지방산 중 DHA 조성이 증가하는 경향을 보였다. 본 연구결과 잘피밭은 자연 먹이의 공급장으로서 방류된 감성돔의 빠른 초기 먹이섭취 및 환경적응에 많은 도움을 준 것으로 판단된다.

• 혜화의학회지
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• 제8권1호
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• pp.593-623
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• 1999

This experimental study was designed to verify the anti-aging efficacy of Eukmigihwangtang (EMGHT) and Rehmannia Radix, and determine the specific role and actions of Rehmannia Radix. Normal rat (2 months old), aging rat (8 months old), and pathologically induced rat (2 months old, injected 30mg/kg of streptozotocin) are observed to study the aging eliciting factors such as peroxide contents and enzyme activities. The following results were obtained in this study: 1. For the body weight changes, normal group given Rehmannia Radix showed decrease in the body weight compared to the control group, aging group given EMGHT and Rehmannia Radix showed significant decrease in the body weight, and STZ injected group showed suppression to the body weight loss when given EMGHT and Rehmannia Radix. 2. For the content changes in serum lipid peroxide, normal group showed increasing level as the rat gets older. Aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant decrease in the lipid peroxide level compared to the control group. Decrease was more prominant in the group given EMGHT. 3. For the changes in serum hydroxyl radical, normal group did not show significant changes, but aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant decrease in the hydroxyl radical level compared to the control group. Decrease was more prominant in the group given EMGHT. 4. For the changes in serum superoxide dismutase (SOD) activity, normal group did not show significant changes, but aging group given EMGHT and Rehmannia Radix showed significant increase in the SOD activity compared to the control group. STZ injected group given EMGHT and Rehmannia Radix showed significant decrease in the SOD activity compared to the control group. 5. For the content changes in hepatic lipid peroxide, aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant decrease in the lipid peroxide level compared to the control group. 6. For the changes in hepatic cytochrome P-450 activity, aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant decrease compared to the control group. Cytochrome b5 activity was significantly decreased only in the STZ injected group given EMGHT and Rehmannia Radix. 7. For the changes in hepatic aminopyrine demethylase and aniline hydroxylase activity, aging group given EMGHT and Rehmannia Radix showed significant decrease compared to the control group. STZ injected group given EMGHT and Rehmannia Radix showed significant increase in the aminopyrine demethylase activity, and showed significant decrease in the aniline hydroxylase activity compared to the control group. 8. For the content changes in hepatic protein bound-SH and nonprotein bound-SH, againg group and STZ injected group given EMGHT and Rehmannia Radix showed significant increase compared to the control group. 9. For the content changes in hepatic glutathione level, aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant increase compared to the control group. 10. For the changes in hepatic glutathione S-transferase activity, aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant increase and decrease, respectively, compared to the control group. 11. For the changes in hepatic glutathione reductase activity, aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant increase compared to the control group, while $\gamma$-Glutamylcystein synthetase activity did not show significant changes. 12. For the changes in hepatic superoxide dismutase activity, aging group and STZ injected group given EMGHT and Rehmannia Radix showed significant decrease compared to the control group. From the above results, the antioxidant effects of EMGHT and Rehmannia Radix were proved, as well as the role of Rehmannia Radix, a chief of EMGHT, was examined. In addition, since no change was reconized as the quantity of Rehmannia Radix and the order herbs increased, the reasonableness on EMGHT was proven with respect to its composition and quantity. Thus, the significance of EMGHT could be objectively exmined in terms of its composition and quantity. Considering animals used in the experiment, there were obvious changes in aging rats and pathologically induced rats than in normal rats. Consequently, it was noticeable that EMGHT and Rehmannia Radix were working selectively on the subjects.

• 한국축산식품학회지
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• 제30권6호
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• pp.951-956
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• 2010

This study was conducted to evaluate the effects of duck-meat consumption on adult disease risk factors, including body compositions, hematological variables, and serum metabolic and lipid profiles in adult human males. To obtain results, 20 adult males aged 20 to 25 were subjected to a diet of 600 g/day of duck-meat for 4 wk, after which body composition, hematological variables, and serum metabolic and lipid profiles were investigated to determine if there was a relationship between duck-meat consumption and adult disease risk factors. The results revealed that high amounts of duck-meat intake did not negatively alter body indices such as body weight, fat mass, body mass index (BMI), % body fat or waste-to-hip ratio (WHR). Furthermore, there were statistically insignificant changes in the number of blood cells, although this number did increase significantly following intake of duck-meat. Moreover, general decreases in serum metabolic parameters were observed, but none of these changes were significant with the exception of the concentration of blood urea nitrogen (BUN). The serum concentrations of LDL-cholesterol also showed a statistically significant decrease by 5.86%. Therefore, this study suggests that the ingestion of duck-meat not only significantly increased the RBC count but also decreased BUN and LDL-cholesterol concentrations in adult males.