• 한국식품영양과학회지
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• 제20권4호
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• pp.300-305
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• 1991

메밀보충급여가 백서의 혈압 및 혈당에 미치는 효과를 검토 하고자 AIN-76 diet와 AIN-76 diet의 탄수화물원을 박피 메밀분으로 교체한 식이로 4주간 사육하여 성장율, 혈당, 인슐린 분비능, 혈압 등의 변화를 측정하고 고찰한 결과는 다음과 같다. 동일실험 기간동안 체중증가량 및 식이섭취량은 대조군과 메밀투여군 사이에 큰 차이를 보이지 않았다. 메밀보충 급여군은 혈당강하작용이 있음이 관찰되었으며, 혈압은 유의성이 없으나 수치적으로 어느 정도 감소시키는 경향을 보였다. 또한 메밀보충급여에 의해 공복시 혈청 인슐린 수준은 낮았으며 혈당을 투여한 후 혈중의 당이 증가하면 분비되는 인슐린 양도 빠르게 증가하는 경향을 나타내었으나 유의성은 없었다.

• 한국인터넷방송통신학회논문지
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• 제23권4호
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• pp.73-78
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• 2023

당뇨병은 전 세계적으로 유병률이 빠르게 증가하고 있는 만성 질환으로, 합병증으로 인한 사망률도 지속적으로 증가하고 있다. 이로 인해 혈당 관리는 현대 사회에서 매우 중요한 과제로 대두되고 있다. 혈당 관리에는 식이요법, 운동요법, 약물요법 등이 있다. 그 중 식이요법은 고혈당을 유발하는 식품을 피하며 혈당 변동을 최소화하는 방법으로, 혈당 관리에 있어서 가장 근본이 되는 기초공사이며, 당뇨병 환자 뿐만 아니라 일반인들도 보다 쉽게 접근할 수 있다. 현재 국내·외 여러 플랫폼에서는 식이요법과 관련하여 식단 구성 서비스를 제공하고 있지만, 이는 주로 사용자나 전문 코치에 의해 수행되고 있다. 이에 따라 본 논문에서는 DNN을 기반으로 한 정확한 Kcal 산출 모델을 구현하고, 이를 기반으로 혈당 관리를 위한 일련의 식이요법 알고리즘을 제시한다.

• Journal of Korean Neurosurgical Society
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• 제37권1호
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• pp.44-47
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• 2005

Objective: The purpose of this study is to investigate the elevated blood glucose levels in the postoperative period are associated with an increased risk of deep wound infection in diabetic individuals undergoing lumbar spine surgery. Methods: Of 2896 patients who underwent lumbar spine operations by one surgeon between 1993 and 2002, 329(11.4%) were diabetics. The rate of deep wound infections in diabetic patients was 6.4%, versus 3.2% for nondiabetics. 152 patients had their operation before implementation of the protocol and 177 after implementation. Charts of the diabetic patients were reviewed. Mean blood glucose levels were calculated from documented results of finger-stick glucometer testing. Results: Twenty-one diabetic patients suffered deep wound infection. Infected diabetic patients had a higher mean blood glucose level through the first 2 postoperative days than noninfected patients($230{\pm}6.9$ versus $175{\pm}3.8mg/dL$; p<0.003) and had a long operation time($216{\pm}57.9$ versus $167.5{\pm}42.2$ minute; p<0.05). Multivariable logistic regression showed that mean blood glucose level for the first 2 postoperative days, long operation time, and use of the instrumentation(p<0.02) were all related predictiors of deep wound infection. Institution of a protocol of postoperative continuous intravenous insulin to maintain blood glucose level less than 200mg/dL was began in september 1997. This protocol resulted in a decrease in blood glucose levels for the first 2 postoperative days and a concomitant decrease in the proportion of patients with deep wound infection, from 8.3%(11/132) to 5.1%(10/195) (p<0.02). Conclusion: The incidence of deep wound infection in diabetic patients is reduced after implementation of a protocol to maintain mean blood glucose level less than 200mg/dL in the immediate postoperative period.

• Journal of Korean Biological Nursing Science
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• 제15권4호
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• pp.164-172
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• 2013

Purpose: The aim was to measure the real-time trans-mission effect of blood-pressure and blood-glucose value based on u-healthcare for saving the time and effort of nursing recording time. Methods: This study used a u-healthcare system based on the international standards for the exchange of health information. In order to verify the effectiveness of the u-healthcare, a clinical trial for the system regarding blood-pressure and blood-glucose targeting of patients with endocrine disorders at KNUH from February 7 to 9, 2012 was performed. Results: According to the analyzed results, of the 86 times the 11 patients were tested, measuring blood-pressure and blood-glucose using the u-healthcare system, we found the time differences between the real-time transfer recording method and existing hospital records that were used in the hospital. Based on the average time interval, there was a difference of 1,090.45 seconds (18.17 minutes). Conclusion: Therefore, it's cumbersome that nurses in the hospital have to record the numerical values of the measured blood-pressure and blood-glucose manually and input the recorded values directly into the electronic nursing record system. However, it was found in terms of the newly designed system, that it could save time and effort for nurses, since measured information is sent to the hospital information system on a real-time basis.

• 한국보건간호학회지
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• 제19권1호
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• pp.5-17
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• 2005

This research was conducted to determine the actual condition of obesity and obese students' total cholesterol. blood glucose and blood pressure, and to analyze the relationship between the obesity rate and total cholesterol. blood glucose and blood pressure among the students at 7 middle schools in A city in Kyoung ki-do. The results were as follows: 1. Among 12,148 student participants in this investigation. students of normal weight range were $91.5\%$ and obese students were $8.5\%$, breaking down to mildly obese of $4.3\%$ $(boys,\;5.4\%;\;girls,\;3.0\%)$. moderately obese of $3.4\% (boys,\;4.6\%;\;girls,\;2.1\%)$ and severely obese of $0.7\%(boys,\;0.9\%;\;girls,\;0.5\%)$, The gender difference was statistically significant $(x^2=111.5830. p=.0001). 2. To analyze the 1.027 obese students. the average of total cholesterol was 166.9mg/dl, 171.0mg/dl and 182.1mg/dl in the mild, moderate and severe obesity groups, respectively. The results became more significant with increasing obesity rate (F=10.06, p=.0001). The average of systolic blood pressure (SBP) was 121.9mmHg, 123.2mm, and 127.5mm, respectively. The results became more significant with increasing obesity rate (F=6.29, p=.0019). The average of diastolic blood pressure (DBP) was 74.4mmHg. 76.0mmHg. and 78.4mmHg, respectively. The results became more significant with increasing obesity rate (F=8.15. p=.0003). The average of blood glucose was 83.3mg/dl, 84.5mg/dl, and 82.3mg/dl, respectively. There was no significant difference with obesity rate. 3. There were significant correlations between obesity rate and cholesterol(r=.11288, p=.0003), between obesity rate and DBP(r=.14209, p=.000l). and between obesity rate and SBP(r=.14081. p=.0001). However, there was no significant correlation between obesity rate and blood glucose (r=.00655, p=.8339).

• 대한간호학회지
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• 제30권6호
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• pp.1479-1487
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• 2000

This study was conducted to draw out prevalence and the risk factors of diabetes mellitus and impaired fasting glucose for adults,(age 30-69). The subjects were 2096 adults, who had regular health examinations between January and December of 1999 at K Hospital in Seoul. The data was analyzed using chi-square test, unpaired t-test and logistic regression. Diabetes Mellitus and impaired fasting glucose were diagnosed by ADA (American Diabetes Association, 1997) criteria. The results were as follows: 1. Mens' prevalence of Diabetes Mellitus was 7.9% and womens' prevalence of Diabetes Mellitus was 3.8%. Mens' prevalence of impaired fasting glucose was 10.4% and womens' prevalence of impaired fasting glucose was 6.5%. Prevalences of Diabetes Mellitus and impaired fasting glucose increased with age. 2. Prevalence of Diabetes Mellitus and impaired fasting glucose of obese subjects (relative body weight>=162) was higher than that of overweight subjects (110<=relative body weight<=119) in men and women. 3. The diagnoses of Diabetes Mellitus and impaired fasting glucose increased with systolic blood pressure and triglyceride. 4. Significant factors associated with diabetes in the logistic regression best gut model were age, relative body weight, systolic blood pressure, triglyceride in men, and systolic blood pressure in women. In conclusion, as age, weight, systolic blood pressure and triglyceride get higher, Diabetes Mellitus and impaired fasting glucose prevalence also increases, porportionally.

• Journal of Korean Biological Nursing Science
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• 제10권1호
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• pp.62-68
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• 2008

Purpose: This study was conducted to test the effect of the 12 weeks brisk walking exercise program on body composition, blood pressure, blood glucose and blood lipid for middle-aged woman with obesity. Method: The subject were 25 obese women in 40-64 yr old who were composed of over 30% body fat. For the analysis, descriptive statistics, paired t-test were used for statical analysis with SPSS 15.0. Result: The results were summarized as follows: first, the body weight, body mass index (BMI), % body fat of the obese woman were significantly decreased after implementing the 12 weeks brisk walking exercise program (p<.5). Second, the systolic blood pressure, diastolic blood pressure and blood glucose were significantly decreased after the 12 weeks brisk walking exercise program (p<.5). Third, the serum cholesterol was significantly decreased (p<.05) but serum triglyceride was not significantly decreased the after 12 weeks brisk walking exercise program. Conclusion: These results suggest that the brisk walking exercise program has an effect on decreasing body weight, BMI, percent body fat, blood pressure and serum cholesterol in middle-aged woman with obesity to reduce obesity and prevent chronic disease.

• 멤브레인
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• 제19권3호
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• pp.222-227
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• 2009

당뇨병 환자의 자가 혈당 측정 장치에 사용할 수 있는 폴리아크릴로니트릴 진단막을 제조하였다. 제조된 폴리아크릴로니트릴 진단막을 여러 가지 환경에서 보관한 후 혈액 속의 글루코우즈의 농도를 변화시켜가며 680 nm에서의 최종 흡광도를 측정하였다. 측정된 혈당치가 보관 온도의 변화에 따라서는 크게 차이를 보이지 않았다. 다만 여러 가지 습도에서 보관한 후 측정한 결과 높은 습도에서 장기간 보관한 후의 혈당치가 기준 값보다 다소 감소하는 것을 알 수 있었다.

• 한국산학기술학회논문지
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• 제10권9호
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• pp.2451-2459
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• 2009

통증이 거의 없는 새로운 모세혈액 채혈기법인 진공자동채혈법(vacuum assisted auto-lancing)의 정확도를 분석하고자 전형적인 대체부위인 전완(팔) 부위에서 채혈하여 측정한 혈당값을 표준 채혈부위인 정맥 및 손가락에서 채혈하여 측정한 혈당값과 비교, 분석하는 연구를 수행하였다. C대학교병원을 내원한 531명의 환자들을 대상으로 왼손 집게손가락 끝과 왼쪽 전완 부위에서 말초혈액의 혈당을 측정하였고, 곧바로 정맥 채혈하여 혈당을 측정하였다. 전완 부위 혈당 평균값이 손가락보다 정맥 혈당값에 더욱 가까웠으나 이들 간의 차이는 약 10 mg/dL 범위에 불과하여 임상적으로는 동일한 값들로 볼 수 있었다. 측정값들 간에 상관분석을 수행한 결과 손가락과 정맥 채혈의 혈당값 간의 상관계수는 0.94, 전완 부위와 정맥 혈당값 간의 상관계수는 0.92, 또한 전완 부위와 손가락 채혈 간의 상관계수는 0.94로 모두 매우 유의한 상관관계를 보였다(p<0.001). 따라서 대체부위인 전완 부위 혈당검사의 정확도가 실험적으로 입증되었다. 손가락 혈당검사는 상당한 채혈 통증이 수반되어 당뇨 환자들이 자가 검사를 기피하는 주요 원인이 되지만, 전완 부위에서 진공자동채혈하면 통증이 거의 없으므로 만성 당뇨환자들의 자가 질환관리를 위해 매우 유용하리라 기대된다.

• Reproductive and Developmental Biology
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• 제34권4호
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• pp.305-308
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• 2010

In this study, we conducted an oral glucose tolerance test (OGTT) so as to compare antidiabetic activities of general potatoes, purple-flesh potatoes, and potato pigments in rats at various concentration levels. After allowing the rats to abstain from food for 12 hours, 10%/20% general potato, purple-flesh potato, and potato extract was orally administered to rats at 100 and 500 mg/kg concentrations. The blood glucose level was measured after an hour. Then, immediately, 1.5 g/kg of sucrose was administered through the abdominal cavity and the blood glucose measured after 30, 60, 120, and 180 minutes. 20% purple-flesh potato group and 10% general potato group, both 100 and 500 mg/kg, showed a significant concentration-dependent decrease in blood glucose levels after 30 minutes. The 100 mg/kg potato pigment group also showed a statistically significant decrease after 30 minutes. In conclusion, administration of 10% general potato, 20% purple-flesh potato, and potato pigment can reduce blood glucose level in an OGTT using rats.