• Preventive Nutrition and Food Science
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• v.6 no.1
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• pp.62-65
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• 2001

Persimmon has been known to help alcohol intoxication in Korea for a long time and is prepared as a processed food. The effect of dried persimmon snacks on alcohol metabolism was determined in vivo. Eight Korean men (25~27 years old) were administered 3.5 mL/kg of alcohol (22.5%, w/v) with or without a dried persimmon snack (2g/kg). The levels of alcohol in the blood and of acetaldehyde in the blood and the urine were determined by alcoholmeter and assay using alcohol dehydrogenase and HPLC, respectively. All subjects showed decreased levels of alcohol in blood, and six subjects showed a decrease of alcohol in urine after consumption of ethanol with dried persimmon snacks. Concentration of acetaldehyde in the blood an urine decreased significantly in three and five of the eight subjects, respectively. Reduction was more significant for alcohol than for alcohol than for acetaldehyde with administration of ethanol and dried persimmon snacks. This in vivo result suggests that dried persimmon snacks are effective in decreasing th concentration of alcohol after alcohol intake.

• The Korean Journal of Food & Health Convergence
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• v.7 no.3
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• pp.33-40
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• 2021

The purpose of this study was to investigate the effects of turmeric intake and weight training on blood alcohol concentration, liver enzyme levels of and their effects on health promotion in adult males. There was no significant difference of taking turmeric powder combined with weight training exercise on blood alcohol levels in adult men who consumed alcohol on a regular basis. There was also no change on the change of body composition. The results were collected from elite athletes that had spent more than 10 years in their respective sports so it is difficult to observe any significant results from 8 weeks, short-term exercises of 1RM 70~80%, 3 times per week. In the next study, it is necessary to divide the subjects into more diverse groups and subject them by varying amounts of turmeric intake, exercise, etc., in order to fully study and understand the effects on blood alcohol level, change, and health promotion. Consequently, this study demonstrated there were no significant differences in the effects of continuous drinking habits of adult men's turmeric powder intake and weight training exercise on changes in GOT, GPT, γ-GTP, and blood alcohol concentrations. Moreover, health improvements themselves didn't affect changes in body composition.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.4
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• pp.610-615
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• 2010

Alcohol is the most widely psychoactive drug and has known in almost all civilization since ancient time. Recently increase consuming alcoholic beverages, alcohol is on of the major public health problems in the world. Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) play important roles in the metabolism of alcohols and aldehydes. The drink consists of medicinal herbs, Puerariae Radix, Phyllostachyos Folium, Citri Pericarpium, Polygonati Rhizoma, Rehmanniae Rhizoma (Vinegar), which have been widely used in oriental medicine. This study was designed to investigate effects of medicinal herbal drink (MHD) on alcohol metabolism in drunken SD rats subjects. In experiment, rats were treated to ethanol (EtOH, 3 g/kg, PO) at 60 min. after saline (CON) or MHD (1 ml/kg, PO) administration. The blood alcohol concentration (BAC), blood acetaldehyde concentration (BALC) activities of ADH, ALDH, AST and ALT were significantly decreased in MHD group than in control group as a time-dependent manner. And drinking water volume in MHD group with duplicate treatment, were significantly decreased than in CON group. These results suggested that MHD intake could give an influence upon the reduction in BAC and BALC may alleviate acute ethanol-induced hepatotoxicity by altering alcohol metabolic enzyme activities.

• Analytical Science and Technology
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• v.26 no.3
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• pp.199-204
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• 2013

In this study, the reproducibility of blood alcohol concentration (BAC) - time profile for the same individuals were investigated. Five Korean males were made to drink 55.5 g of ethyl alcohol (neglecting body weight) in the form of undiluted Soju (22% v/v), Korean popular liquor, within 30 min and each drinking sessions were performed for five times. Two kind of side dishes, a sliced raw fish and a sweet and sour pork, were served alternately along with alcohol. The peak BAC reaching time, the maximum BAC and the reduction rate of BAC of an individual varied greatly even though the dose and drinking time interval were not changed. Also, the food taken along with alcohol varies the shape of BAC - time profile. From the repetitive drinking sessions we can know that the BAC - time profile of an individual is not a reproducible one even though the dose, kind of liquer, drinking time and food were maintained constantly. It means that any assumption of blood alcohol concentration of an individual at a previous time stage based on the alcohol dose can not be justified because of large fluctuation of BAC-time profile of an individual.

• The Korea Journal of Herbology
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• v.24 no.4
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• pp.159-164
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• 2009

Objectives : The purpose of this study is to evaluate antioxidant activities and reducing serum alcohol concentration of extract of Lentinus edodes on the alcohol administered rats. Methods : Antioxidant effect was measured by total phenolic compound and DPPH-radical scavenging activity of extract of Lentinus edodes in vitro. Blood alcohol concentration, aldehyde concentration, malondialdehyde concentration, glutathion concentration were measured in vivo. Results : The extract of Lentinus edodes increased DPPH-radical scavenging activity dose-dependently. The water extract with boiling water showed lower antioxidant activity and phenolic content than 70% ethanol extract in vitro. Blood alcohol concentration was significantly reduced by pre-treatment of ethanol extract of Lentinus edodes. The effect was more significant than commercial product used as a positive control. Conclusions : This study suggest that Lentinus edodes can be a potential nature resource for the management of ethanol toxicity although the mechanism of action involved in the treatment remains to be explored.

• Journal of Preventive Medicine and Public Health
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• v.25 no.2 s.38
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• pp.141-147
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• 1992

This study was carried out not only to determine blood alcohol levels by time but also to examine the changes of working ability and reaction speed after ingestion of alcohol. Fifteen healthy students aged from 21 to 27 volunteered as subjects for this study, Liguor (Sojoo) in concentration of 25% ethyl alcohol was administrated with the amount of 1ml of ethyl alcohol per kg of body weight to the subjects. The concentration of alcohol in the blood were determined by the 'Alcohol Sensor 100' at 5, 30, 60 and 90 minutes after the administration of alcohol. Also, the choice reactiontest, the eye-hand coordination test and kraepelin test were examined at the same time after checking of alcohol concentration in the blood. The results of this study can be summarized as follows. 1. Mean blood alcohol level changes resulting from administration of 1ml of ethyl alcohol per kg of body weight were $0.16%(160{\pm}57mg/100ml,\;0.10%(100{\pm}42mg/100ml),\;0.08%(80{\pm}36mg/100ml)\;and\;0.03%(30{\pm}24mg/100ml)$ at the 3, 30, 60 and 90 minutes after the administration respectively The peak in the concentration of blood alcohol was 5 miniutes after the ingestion according to alcohol examination by the respiration. 2. As for choice reaction test, reaction times became prolonged as blood alcohol levels increased. The reaction time showed a significant changes when the blood alcohol concentration reached 0.08% or more after alcohol ingestion. 3. In eye and hand coordination test, the accuracy of the performance became decreased as blood alcohol levels increased. The difference of accuracy of the test was significantly shown when alcohol levels in the blood reached 0.08% or more after alcohol intake. 4. As for kraepelin test, the abilities of calculation also became lowered as blood alcohol levels increased. The abilities of calculation differed signigicantly from control group when alchool levels of 0.08% and more.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.1
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• pp.498-506
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• 2015

This paper investigates the association of among alcohol consumption and blood vitamin D and lead concentrations. Subjects to 4,074 with adults over the age of 20 in the 5th Korea National Health and Nutrition Examination Survey, correlation analysis is used to validate the relations between an average daily alcohol consumption and blood vitamin D and lead concentration, and to study the effects of blood vitamin D to the lead concentration is carried out regression analysis. The correlation analysis shows that alcohol consumption has the correlation with blood vitamin D and lead concentration(p<0.01). As the results of regression analysis, age(p<0.01), education(p<0.01), occupation(p<0.05), alcohol consumption(p<0.01), vitamin D(p<0.05) appear significant influence on lead concentration in male. Alcohol consumption increases not only lead concentration but also vitamin D. Blood vitamin D also contributes to the rise in lead concentration, but in the reverse the metabolic activity of blood vitamin D by influence of lead receives a negative effect in our body.

• Korean Journal of Community Nutrition
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• v.10 no.3
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• pp.281-289
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• 2005

Hyperlipidemia and related heart disease will be growing public health problems as the population ages. It is therefore of great importance to identify modifiable risk factors. So this research investigated associations among life style, nutrient intake, and blood lipids in middle-aged men with borderline hyperlipidemia. Dietary intakes were assessed by food-frequency questionnaire and convenient method. The subject's histories of alcohol use and smoking were assessed via a questionnaire. Current smokers were classified as smokers, whereas past smokers and subjects who never smoked were classified as nonsmokers. With regard to alcohol intake, the subjects were stratified into drinkers and nondrinkers. In drinkers the frequency were measured. Frequency of alcohol intake and weight were associated with high blood lipids and blood pressure. The highest quartile of calcium intake had lower triglyceride concentration than did those in the lower three quartiles. High calcium intake was associated with low blood triglyceride concentration. These results suggest that healthy weight and high calcium intake and less alcohol intake can contribute to maintenance of healthy blood lipids in men.

• The Korean Journal of Food And Nutrition
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• v.22 no.4
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• pp.479-484
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• 2009

This study investigated the characteristics of baking bread and cookies supplemented with taurine and the effect of taurine addition on BAC(blood alcohol concentrations) and UAC(urine alcohol concentrations). Healthy male college students were divided into two groups, the control and the taurine group. Bread was baked with the addition of 0, 2, 4 and 6% taurine and baked with the addition 0, 3 and 6% taurine. The bread containing 2% taurine showed the fastest fermentation among the 4 groups. Fermentation and oven-spring of breads baked with a taurine concentration greater than 4% of taurine disturbed. In some areas of the sensory test, the taurine supplemented bread had higher scores than the control bread. We served 6 g of taurine supplemented cookies with 1,000 $m{\ell}$ of beer to 8 students in the taurine group. After 2 hours of drinking beer, the BAC and UAC of the taurine group were found to be lower than the control group. But no difference was found in the alcohol excretion of their urine. From this study we concluded that the taurine has an effect on the detoxication of alcohol, which reduces the BAC.

• Korean Journal of Medicinal Crop Science
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• v.6 no.2
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• pp.126-130
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• 1998

Effects of organic solvent fractions from perilla ethanol extract on alcohol metabolism in rats were examined and the results were as follows: Ethanol souble fraction, after a single oral administration to rats, was found to cause a significant decrease in the serum ethanol concentration as well as enhancement of liver cytosolic alcohol dehydrogenase (ADH) activity. On the other hand, the fraction insouble in ethanol was found to increase ethanol concentration in the blood and inhibit ADH activity.