• 한방안이비인후피부과학회지
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• 제20권2호통권33호
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• pp.89-101
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• 2007

Objectives : This study was carried out to investigate the effects of Jeondo-San(JDS) on anti-Inflammation and anti-Propionibacterium acnes. Methods : The effects of JDS on anti-Inflammation and anti-Propionibacterium acnes were measured by the cytotoxicity of Raw 264.7 cell, the inhibition for NO, $TNF-{\alpha}$, $PGE_2$, iNOS and COX-2, the blocking $NF-{\kappa}B$ into nucleus and the sterilizing power for Propionibacterium acnes. Results : 1. All concentrations of JDS has no cytotoxicity in Raw 264.7 cell. 2. All concentrations of JDS inhibited the production of NO in the Raw 264.7 cell stimulated with LPS. 3. All concentrations of JDS did not significantly inhibit the production of $TNF-{\alpha}$ in the Raw 264.7 cell stimulated with LPS. 4. All concentrations of JDS inhibited the production of $PGE_2$ in the Raw 264.7 cell stimulated with LPS. 5. All concentrations of JDS did not inhibit the expression of COX-2 but concentrations of 50\;{\mu}g/ml$, 100\;{\mu}g/ml$ JDS inhibited iNOS expression in the Raw 264.7 cell stimulated with LPS. 6. Concentrations of 50\;{\mu}g/ml$, 100\;{\mu}g/ml$ JDS has the effect of blocking $NF-{\kappa}B$ into nucleus in LPS-induced macrophage Raw 264.7 cell. 7. All concentrations of IDS did not have the inhibitory effect of Propionibactrium acnes. Conclusions : The present date suggest that JDS has a effect on the stage of inflammation of acne.

• 한국발생생물학회지:발생과생식
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• 제17권1호
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• pp.37-43
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• 2013

Cynomorium songaricum (CS) has been used in traditional Korean medicine in treating male impotence and sexual dysfunction. We investigated the effects of aqueous CS extract on the reproductive activity of golden hamsters whose spermatogenetic capacity is active in summer and inactive in winter. The animals were divided into 5 groups: long photoperiod (LP) control, short photoperiod (SP) control, and SP animals treated with low, middle, or high concentrations of CS. The animals were orally ingested with low (0.5 g/kg), middle (1.0 g/kg), or high (2.5 g/kg) concentrations of the aqueous extracts for 8 weeks on the daily basis. The control animals received the vehicle. As results, the LP control animals showed active testicular function but SP control animals displayed remarkably reduced testicular weights. The outcomes of the reproductive activity from low and middle concentrations of CS treatments were identical and marked as low dose. The consequences were a partial blocking of regressing activity by SP. On the other hand, the animals treated with high dose of CS extract showed remarkable significance in comparison to the SP control, indicative of a complete blocking effect of the CS on the regressing testes by SP. There were a dose-dependent effects of the CS on the sexual function. These results suggest that the CS extract promotes the male fertility by strengthening the spermatogenesis in the golden hamsters.

• 대한약리학회지
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• 제12권2호
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• pp.13-19
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• 1976

A fluid extract of Zizyphi Semen was employed in this experiment. The cardiac effects of Zizyphi Semen were examined on isolated rabbits atria and heart in situ of anesthetized cats and rabbits. The adrenergic blocking activity and refractory period of cardiac muscle were measured after administration of this drug. In rabbits and cats the antiarrhythmic action of Zizyphi Semen on atrial and ventricular arrhythmias produced by epinephrine or ouabain was examined. The results were following: 1. Zizyphi Semen produced a decrease in rate and contractile amplitude of the isolated rabbit atria and had a week blocking effect on epinephrine acceleration of atrial movement. 2. Zizyphi Semen effectively abolished the spontaneous arrhythmia occurring in the isolated rabbit atria ana the atrial arrhythmia induced by ouabain. 3. Zizyphi Semen produced a marked prolongation of the refractory period in isolated atrial muscle of rabbit. 4. Zizyphi Semen prevented the induction of ventricular arrhythmia arising from excessive dose of epinephrine in anesthetized rabbits and cats. 5. With regard to the ventricular arrhythmia induced by a continuous infusion of ouabain, Zizyphi Semen exerted suppressive effect and produced a marked prolongation of cardiac arrest time in anesthetized rabbits and cats. From the above results, it may be concluded that Zizyphi Semen is effective against atrial and ventricular arrhythmias. The antiarrhythmic effect of this drug may be the result of direct myocardial depressive and partially adrenergic beta receptor blocking activities including prolongation of the refractory period of cardiac muscle.

• 한국염색가공학회지
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• 제22권1호
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• pp.71-76
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• 2010

In this study the optimum dyeing conditions and blocking effect of UV deodorization efficiency of Ligustrum japonicum Thunb were investigated. Colorants were water-extracted from Ligustrum japonicum Thunb fruit and freeze-drided to obtain colorants powder. The effects of dye concentration, dyeing temperature, dyeing time, and the number of dipping count were studied. Fastness to dry cleaning, rubbing, perspiration, and light were measured according to KS K 0644, KS K 0650, KS K 0715 and KS K 0700, respectively. In order to examine the dyeability according to dyeing conditions, reflectance of fabrics were measured by using UV/VIS spectrophotometer. The bath ratio was 1:20. Dyeing concentration was 100, 200, 300, 400 and 500% on the weight of fiber. Dyeing time was 20, 40, 60, and 80 minutes. Dyeing temperature was 20, 40, 60, 80, and $100^{\circ}C$. The infrared high pressure dying machine was used. As dyeing concentration increased, dye adsorption increased up to 400% and it slowed down. Dye uptake was increased with raising themperature up to $80^{\circ}C$ and it slowed down. Dye adsorption occurred rapidly at first 20 minutes and then it slowed down and reached almost maximum dye uptake at 60 min. Dye uptake increased by repeated dyeing. Therefore, it is considered that optimum dyeing condition is 400%(o.w.f.), $80^{\circ}C$, 60 min. And repeated dyeing improves dye uptake. Color fastness to dry cleaning and rubbing was good, but light fastness and perspiration fastness was not good. Blocking effect of ultraviolet radiation and deodorization efficiency was good.

• 대한화학회지
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• 제54권4호
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• pp.460-464
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• 2010

2-hydroxy-4-methoxy-benzophenone과 titanium(VI) isopropoxide를 나노 금과 나노백금을 사용하여 자외선 차단과 항균성을 갖는 기능성 콘택트렌즈를 제조하였다. 콘택트렌즈는 캐스트 몰드 법을 사용하여 제조하였으며, $70^{\circ}C$에서 약 40분, $80^{\circ}C$에서 약 40분 건조하였다. 마지막으로 $100^{\circ}C$에서 약 40분 열처리 공정을 거쳐 공중합 하였다. 물리적 특성을 측정한 결과 굴절률은 1.434 ~ 1.436, 함수율은 35.24% ~ 36.32% 그리고 가시광선 투과율은 88.3% ~ 90.8%를 나타내었다. 생성된 고분자는 콘택트렌즈를 제조하는 데에 필요한 물리적 특성을 만족하였으며, 안 의료용 기능성 소재로의 응용이 충분히 가능할 것으로 판단된다.

• Composites Research
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• 제20권3호
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• pp.50-54
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• 2007

본 연구에서는 IPMC의 기본적인 기계적 특성을 알아보았다. 기전폴리머의 한 종류인 IPMC는 굽힘형 작동, 가벼움, 저전력 소모, 유연성 등의 많은 장점을 가진 재료이다. 따라서 IPMC는 생체모방형 작동기와 센서로서 많은 가능성을 가지고 있다. 이런 가능성을 바탕으로 IPMC를 실제로 응용하기 위하여 IPMC의 변형, 구동력, 주파수 응답 등 기본적인 기계적 특성을 연구하였다. 우선 이온교환폴리머의 한 종류인 네피온 용액을 사용하여 여러 가지 두께의 네피온 막을 만들고, 무전해 도금을 통해 IPMC를 제작하였다. 이렇게 제작된 IPMC의 규격, 인가 전압에 따른 변형, 구동력, 주파수 응답 특성에 관한 실험을 수행하고, 실험 결과를 통해 IPMC 성능의 실험식과 등가 강성 모델을 수립하였다.

• Journal of applied mathematics & informatics
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• 제31권1_2호
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• pp.311-325
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• 2013

The effects of the moments of the interarrival time and service time on the system performance measures such as blocking probability, mean and standard deviation of the number of customers in service facility and orbit are numerically investigated. The results reveal the performance measures are more sensitive with respect to the interarrival time than the service time. Approximation for $GI/G/c$ retrial queues using $PH/PH/c$ retrial queue is presented.

• 대한자원환경지질학회:학술대회논문집
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• 대한자원환경지질학회 2000년도 춘계 공동학술발표회
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• pp.84-85
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• 2000

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 1998년도 학술대회
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• pp.91-94
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• 1998

본 논문에서는 블록간, 블록 내수, 수평. 수직 방향성, 그리고 시간 영역의 정보를 이용하는 압축 동영상의 블록화 및 링 현상을 제거하는 방식을 제안한다. 위의 정보를 이용하여 새로운 부가 함수가 정의되며, 최적 해를 구하기 위해 gradient와 projection을 결합시킨 hybrid 형태의 기법을 이용한다. 또한, 정규화 계수들 및 projection을 위한 영역의 설정을 부호화단에서는 이용 가능한 정보로부터 추출하게 되므로 계산량을 감소시킬 수 있다. 실험 결과로부터 제안된 방식의 효율성을 확인할 수 있다.

• 한국지반공학회지:지반
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• 제12권3호
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• pp.99-108
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• 1996

본 연구에서는 케미칼 그라우팅웅의 폴리우레탄계 2성분 주입약액 및 그의 반응고결물인 발포 고결체의 물리적, 화학적 성질에 관하여 조사하였다. 이들의 성질을 좌우하는 요소들을 규명키 위한 실험결과, 폴리우레탄계 주입약액 및 그의 고결생성물의 물리적, 화학적 거동은 토질의 상태 즉, 온도, 함수비 및 흙의 밀도 등과 같은 주입대상지발의 조건에 의해 크게 영향받는 것을 알 수 있었다. 또한, 폴리우레탄계 약액그라우팅의 지반보강효과 및 차수효과를 검증키 위해 현재 건설중인 지하철등에서의 터널 굴착시의 폴리우레탄계 약액주입 시공예를 중심으로 그 효과를 조사하였다.