• Title/Summary/Keyword: bleeding

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Dental Management in a Patient with Glanzmann's Thrombasthenia : A Case Report (글란즈만 혈소판무력증 환자의 치과적 관리)

  • Han, Miran;Kim, Jongsoo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.47 no.3
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    • pp.352-358
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    • 2020
  • Glanzmann's thrombasthenia (GT) is a rare, autosomal recessive inherited congenital disorder, characterized by impaired blood coagulation due to platelet dysfunction. It was first reported by the pediatrician Glanzmann in 1918. GT affects both males and females, and it is more common in regions of the Middle East, India, and France, where intermarriage is common. It has an incidence of about 1 in 1,000,000 people. In South Korea, according to the Division of Rare Diseases, Korea Centers for Disease Control and Prevention, around 200 cases have been reported in 2018. Clinical symptoms include petechia, ecchymosis, epistaxis, and gingival bleeding. The spontaneous loss of deciduous teeth can result in excessive bleeding with that blood transfusion should be considered. Preventing hemorrhages and hemostasis are most important factors in dental treatment. Local bleeding can be controlled by compression, but platelet transfusion can be required by prolonged bleeding. Pediatric dentists can minimize the gingival bleeding by control of the oral hygiene to prevent gingivitis and dental caries. The importance of oral hygiene and periodic recall check-up should be emphasized. During dental treatment, the examination and the treatment plan of patient should be modified to prevention of hemorrhages carefully. A 6-year-old girl with GT was referred for the treatment of dental caries, and resin restoration was performed under nitrous oxide inhalation sedation. After treatment, compression was required for the bleeding control.

Bleeding characteristics of coupling materials for installation of acoustic emission (AE) sensor (AE 센서 설치를 위한 커플링 재료의 블리딩 특성)

  • Lee, Jong-Won;Kim, Hyunwoo;Kim, Min-Koan;Oh, Tae-Min
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.4
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    • pp.635-650
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    • 2017
  • Acoustic emission (AE) sensors have broadly used to monitor the damage of underground structures and tunnels. The reliability of measured signal is determined by the coupling condition of the AE sensors which are embedded in the target underground structure. To secure the reliability of health monitoring results, it is important to understand the characteristics of the coupling materials. In this study, laboratory tests were performed using portland cement, micro cement, and gypsum as coupling materials in order to verify the bleeding characteristics. The effective parameters for bleeding were determined to be water-cement ratio, material type, curing time, and injected volume of coupling materials. As a results of the experimental study, the bleeding rate increases with an increase in a water-cement ratio and an injected volume; for portland cement, water-cement ratio and injected volume effects are larger than the micro cement. However, curing time is not much effective for occurrence of the bleeding phenomenon. It is anticipated that this study may be useful for the selection of suitable coupling materials for installation of acoustic emission sensors.

The Use of Nafamostat Mesilate as an Anticoagulant during Continuous Renal Replacement Therapy for Children with a High Risk of Bleeding (출혈성 경향이 높은 소아환자의 지속성 신대체 요법시 사용되는 항응고제로서 Nafamostat mesilate의 사용)

  • Lee, Sang Taek;Cho, Heeyeon
    • Childhood Kidney Diseases
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    • v.18 no.2
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    • pp.98-105
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    • 2014
  • Purpose: Nafamostat mesilate (NM), a synthetic serine protease inhibitor, has been investigated as an anticoagulant for adult patients with a high risk of bleeding, who need chronic renal replacement therapy (CRRT). However, little is known about the use of NM as an anticoagulant in pediatric CRRT. The aim of this study was to evaluate the ideal dosage, efficacy, and safety of NM in pediatric CRRT. Methods: We conducted a retrospective study of 40 pediatric patients who had undergone at least 24 h of venovenous CRRTs between January 2011 and October 2013. We divided the patients according to risk of bleeding. Those at high risk received no anticoagulation (group 1) or NM as an anticoagulant (group 2), while those at low risk received heparin (group 3). Results: Forty patients (25 male and 15 female; mean age, $8.2{\pm}6.6$ years) were enrolled. The mean duration of CRRT was 13.0 days, and the survival rate was 57.5%. The mean hemofilter lifespan was 39.3 h in group 1 and 11.3 h in group 3. In group 2, hemofilter lifespan was extended from 7.5 h to 27.4 h after the use of NM (P =0.001). The mean hemofilter lifespan with NM was greater than with heparin (P =0.018). No patient experienced a major bleeding event during treatment with NM. Conclusion: NM may be a good alternative anticoagulant in pediatric patients with a high risk of bleeding requiring CRRT, and is not associated with bleeding complications.

Effect of worsening family economy due to COVID-19 on gingival bleeding and pain in Korean adolescents (우리나라 청소년의 COVID-19로 인한 가정경제악화가 치은 출혈 및 통증에 미치는 영향)

  • Kim, So-Yeong
    • Journal of Korean society of Dental Hygiene
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    • v.21 no.6
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    • pp.695-701
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    • 2021
  • Objectives: This study aimed to determine the effect of COVID-19-induced household economic deterioration on gingival pain and bleeding. Methods: Data from the 16th Adolescent Health Behavior Survey 2020 were used. A total of 57,925 adolescents were included in this cross-sectional study. We evaluated the worsening of the COVID-19-induced household economic situation, gingival pain, and bleeding. All surveys were assessed in a subjective non-face-to-face online interview. Data were analyzed using descriptive statistics, chi-squared tests, and logistic regression. Results: The overall prevalence of gingival pain and bleeding symptoms in the study population was 19.2%. People with COVID-19 were more likely to suffer from gingival pain and gingival bleeding than those who did not have economic deterioration due to COVID-19. There was no economic deterioration due to COVID-19 (aOR=1.048, 95% CI=1.034-1.227) and worsened very much (aOR=1.358, 95% CI=1.164-1.585). Conclusions: There were more cases of gingival pain and gingival bleeding, which are early symptoms of periodontal disease, in patients with COVID-19 compared to cases without deterioration of the household economic situation due to COVID-19. It is necessary to measure and study gingival bleeding objectively rather than relying on self-reports.

Transcatheter Arterial Embolization for Palliation of Uterine Body Cancer Bleeding (자궁체부암 출혈에 대한 보존적 치료로써의 경카테터 동맥 색전술)

  • Jaeyeon Choi;Ji Hoon Shin;Hee Ho Chu
    • Journal of the Korean Society of Radiology
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    • v.84 no.3
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    • pp.606-614
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    • 2023
  • Purpose This study aimed to evaluate the efficacy and safety of transcatheter arterial embolization (TAE) for bleeding due to uterine body cancer. Materials and Methods In this retrospective study, six patients with varying types of uterine body cancer who underwent TAE for bleeding control were investigated. Angiographic findings, cross-sectional images, TAE details, and clinical outcomes were studied. Technical and clinical success rates were calculated. Results The identified patients had endometrioid adenocarcinoma, sarcoma, and gestational trophoblastic neoplasia, and most were patients with advanced-stage cancer. In four patients, tumor bleeding presented as vaginal bleeding. Technical success was achieved in all seven TAE procedures in six patients. Two patients with recurrent masses who had undergone hysterectomy presented with hematochezia, and TAE was able to provide technical success in these patients as well. The clinical success rate was 50%, indicating bleeding control for > 1 week. Rebleeding was directly associated with death in one patient. On the following day, mild fever was observed in one patient. Conclusion TAE can be considered an effective and safe method of bleeding control for uterine body cancer, especially during critical periods throughout the disease course of patients with inoperable, advanced-stage cancer.

Massive Hemorrhage Facial Fracture Patient Treated by Embolization

  • Kim, Moo Hyun;Yoo, Jae Hong;Kim, Seung Soo;Yang, Wan Suk
    • Archives of Craniofacial Surgery
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    • v.17 no.1
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    • pp.28-30
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    • 2016
  • Major maxillofacial bone injury itself can be life threatening from both cardiovascular point of view, as well as airway obstruction. Significant hemorrhage from facial fracture is an uncommon occurrence, and there is little in the literature to guide the management of these patients. We report a 73-year-old male driver who was transported to our hospital after a motor vehicle collision. The patient was hypotensive and tachycardic at presentation and required active fluid resuscitation and transfusion. The patient was intubated to protect the airway. All external attempts to control the bleeding, from packing to fracture reduction, were unsuccessful. Emergency angiogram revealed the bleeding to originate from terminal branches of the sphenopalatine artery, which were embolized. This was associated with cessation of bleeding and stabilization of vital signs. Despite the age and severity of injury, the patient recovered well and was discharged home at 3 months with full employment. In facial trauma patients with intractable bleeding, transcatheter arterial embolization should be considered early in the course of management to decrease mortality rate.

The Effects of Position Change on Low Back Pain, Discomfort, and Bleeding after Transarterial Chemoembolization (체위변경이 간동맥 화학색전술 환자의 요통, 불편감, 출혈 합병증에 미치는 효과)

  • Yun, Mi-Jeong;Min, Hye Sook
    • Korean Journal of Adult Nursing
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    • v.26 no.4
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    • pp.424-433
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    • 2014
  • Purpose: This study was to test the effects of the positional change on low back pain, discomfort, and bleeding complications during the period of bed rest following transarterial chemoembolization (TACE). Methods: The research design for this study was a non-equivalent control group quasi-experimental design. The participants were 23 patients for the experimental group, and 23 patients for the control group. The experimental group received positional change of taking the semi-Fowler's position and the 30-degree lateral position alternatively during the period of bed rest after TACE for 4 hours at one-hour intervals. The control group maintained the supine position continuously during the period of bed rest after TACE. Results: There were statistically significant differences in low back pain and discomfort between the experimental and the control group after intervention. And no significant difference was found in bleeding complication between two groups. Conclusion: The results of the study suggest that the positional change is an effective nursing intervention to reduce low back pain and discomfort without increasing the risk of bleeding after TACE.

Effect of health behavior on periodontal disease of adolescents (청소년의 건강행태가 치주질환에 미치는 영향)

  • Ma, Jae-Kyung;Park, Eui-Jung;Kim, Chang-Yoon
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.4
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    • pp.617-623
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    • 2016
  • Objectives: The purpose of this study is to investigate the effect of health behavior on oral health of Korean adolescents. Methods: The study subjects were 1,071 adolescents of 13-18 years old from Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2012. Male students were 54.5% and female students were 45.5%. The study consisted of two groups: 13-15 years old and 16-18 years old groups. Data were analyzed by SAS 9.13 version. Results: Those who ingested alcohol had gingival bleeding in 41.0% and 31.0% in those who did not. Those who did not have regular oral examinations had 38.5% of gingival bleeding while those with regular oral examination had 29.7% of gingival bleeding (p<0.01). Students between 16 to 18 years old without oral care products tended to have more gingival bleeding than those who use auxiliary oral hygiene devices (OR=2.658, 95% CI=1.327-5.324). Conclusions: The oral health management of adolescents is closely related to health behavior. Cessation of alcohol ingestion and smoking is very important to improve the adolescent oral health.