• Title/Summary/Keyword: biological value

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A study on the Effects of Organism Vigor Information Solution to the Growth of Tumor-Derived Animal Cell (생물활성정보수가 종양 유래 동물세포 성장에 미치는 영향에 관한 고찰)

  • Jang, M.Y.;Lee, K.S.;Shin, J.W.;Mun, C.W.
    • Journal of Biomedical Engineering Research
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    • v.32 no.3
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    • pp.185-190
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    • 2011
  • The purpose of this study is to investigate the influence of organism vigor information solution(OVIS) on the animal cell growth and to set up a condition for cell culture. We investigated the reactions on the MG-63 and MCF-7 cell line in mixture culture media with various amount of REVIEW solution, which is an example among various OVIS. DMEM-HG was used as basic media. The concentration range of the mixture was limited from 0% to 15%. MTT assay is used for cell viability test. The cell was incubated for 14days and the MTT assay was performed on day 1, 3, 7, 10 and 14 throughout the experiment. We used the ELISA reader to measure the Optical Density(O.D) at 595 nm wavelength filter. MCF-7 was linearly proliferated according to culture time and concentrations of OVIS. On the other hand, MG-63 cells were measured the highest O.D value at 12%. The growth rates of both cells cultured in mixed culture media with OVIS are much higher than those in only basic media, DMEMHG, after 14days. It was confirmed that cell cultured at OVIS grows rapidly at certain period although cells showed a negative effect in initial stage.

The Investigation of the Relationship between Eye Blink and Visual Attention with Video Clip (영화클립을 이용한 눈깜빡임과 시각적 주의력과의 상관성 연구)

  • Kim, Sung Kyung;Kang, Min;Kang, Geon Ju;Park, Sujie;Shin, Young Seok;Jang, Dong Pyo
    • Journal of Biomedical Engineering Research
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    • v.35 no.4
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    • pp.99-104
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    • 2014
  • Generally, human eye blinks are closely associated with the cognitive state or visual attention such as attentional requirements on visual stimuli. These previous studies have reported that eye blinks are related to explicit visual attention using blink rate, pattern and blink timing across subjects. However, these results have been obtained in a well-controlled experimental settings. So, it would prove difficult to investigate human's natural response in a continuous and realistic situation. In our study, we measured the eye blink intervals while participants viewed a movie clip. And we analyzed the blink interval data for relationship between visual attention and eye blink intervals. 24 participants took part in two experimental sessions, first session to measure the IEBI while viewing the movie clip and second session to conduct a memory performance test using a self-questionnaire, which were spaced 3 weeks apart. The results indicate significantly higher memory performance at long IEBI period than short IEBI period while watching a movie clip(t = 3.257, df = 17, p < 0.005, 2-tailed). In addition, memory performance score significantly correlated with the IEBI value(spearman's rho = 0.40, N = 36, p < 0.01, 2-tailed). Our results suggest that IEBI is used to measure or assess visual attention while wiewing the movie that it is capable of simulating aspects of real-life experiences by visual attention. Thus, we expect IEBI to be used to measure or assess our visual attention, cognition, further emotion about not only movies, advertisements and other cultural contents but also cognitive science.

Ecotoxicological Evaluation of Synthetic Surfactant (합성세제의 생태독성 평가)

  • 최병기;홍사욱;한상욱
    • Environmental Analysis Health and Toxicology
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    • v.9 no.3_4
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    • pp.91-101
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    • 1994
  • In order to evaluate the ecotoxicological harzardousness of synthetic surfactants on Han river, Jung-ryang and Jin-Wi stream, we used the Ecotoxicological Risk Quotient (ERQ). The chemical harzardousness is evaluated by the balance of the toxicity and concentration in the environment.. Then, ERQ is defined as follows; ERQ = - log ( Concentration in the environment / Effective concentration in the test ) ERQ of chemical is a logtrighmic value of ratio of a chemical concentration and the toxicity in the laboratory. In case of small ERQ, tie chemical harzardousness is high. If ERQ equals O, the same biological effect as in the laboratory test will be observed in the enviromment by the chemicals. ERQ values of the chemicals were calculated using the maximum concentration in water environment which were cited from the annual report by our ministry of environment, and EC$_{50}$ of Daphnia magna (water flea; acute immobilization test) LC$_{50}$ of Oryzias latipes (fish; acue toxicity test) and EC$_{50}$ of chlorella vulgaris (alga; growth inhibition test), which were taken from the annual report of "Chemical in environment" by Japan EA. Liner alkylbenzene sulfonate (determined to MBAS) showed the high average values with more than 2.0 to three species in Han river and Jin-wi stream, and these results mean to be favorable to environmental safety. The areas of Jung-ryang stream were polluted, as the average values of ERQ were less than 2.0 with equal to three species, and attention should be paid. Therefore, they must be inspected again because their concentration in the environment may have changed during that period. The chemical harzardousness can be numerated with ERQ, and it can be a help to find the chemicals that should be kept under observation and to see whether the chemical pollution is improved or worsened. The determination of the chemical concentration in the environment and toxicity are essential for the effective use of ERQ.se of ERQ.

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Changes of Physicochemical Characteristics of Korean Type Hot Sauce during Storage (한국식 핫소스의 저장 중 이화학적 특성 변화)

  • Kwon, Dong-Jin;Lee, Sung;Kim, Yoo-Jin;Yoo, Jin-Yong;Jung, Kun-Sub
    • Korean Journal of Food Science and Technology
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    • v.30 no.3
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    • pp.548-551
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    • 1998
  • Physicochemical characteristics of the Korean type hot sauce during storage were investigated. Chemical analysis of the Korean type hot sauce showed as follows; pH 3.29, titratable acidity 3.88%, capsanthin 0.13% and capsaicin 2.68 mg%. The contents of capsanthin and capsaicin except pH and titratable acidity decreased during storage for 50 days at 20 and $30^{\circ}C$. The results of sensory evaluation showed the decrease of value according to storage time. Especially change of color in sensory evaluation was outstanding. For correlationship between the color of sensory evaluation and capsanthin content was high, capsanthin content was selected as a quality index of the Korean type hot sauce. Shelf-lives of the Korean type hot sauce were predicted to be 232.5 days at $20^{\circ}C$, and 178.0 days at $30^{\circ}C$, respectively.

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Candidate Marker Identification from Gene Expression Data with Attribute Value Discretization and Negation (속성값 이산화 및 부정값 허용을 하는 의사결정트리 기반의 유전자 발현 데이터의 마커 후보 식별)

  • Lee, Kyung-Mi;Lee, Keon-Myung
    • Journal of the Korean Institute of Intelligent Systems
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    • v.21 no.5
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    • pp.575-580
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    • 2011
  • With the increasing expectation on personalized medicine, it is getting importance to analyze medical information in molecular biology perspective. Gene expression data are one of representative ones to show the microscopic phenomena of biological activities. In gene expression data analysis, one of major concerns is to identify markers which can be used to predict disease occurrence, progression or recurrence in the molecular level. Existing markers candidate identification methods mainly depend on statistical hypothesis test methods. This paper proposes a search method based decision tree induction to identify candidate markers which consist of multiple genes. The propose method discretizes numeric expression level into three categorical values and allows candidate markers' genes to be expressed by their negation as well as categorical values. It is desirable to have some number of genes to be included in markers. Hence the method is devised to try to find candidate markers with restricted number of genes.

Syntheses of Biologically Active Phosphinate Derivatives with a Pendant Monoazacrown Ether (모노아자크라운에테르 기능기를 가진 생리활성 포스피네이트 유도체의 합성)

  • Nam Chong-Woo;Chung Yeong-Jin;Yang Il-Woo
    • Journal of the Korean Chemical Society
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    • v.37 no.1
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    • pp.154-161
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    • 1993
  • Four kinds of new phosphinate derivatives with a pendant monoazacrown ether were synthesized and their biological activities were tested. These biologically active phosphinates were synthesized in relatively good yields (61∼72%) by one step reactions of phenylphosphinate with aldehyde and monoazacrown ether. Toxicity of these compounds was tested by intraperitoneal injection of the compounds to male mouse and revealed $LD_{50}$ value of 65∼90 mg/kg, which showed enhanced toxicity by attachment of a pendant azacrown ether to a simple phenylphosphinate structure. Although the ring size effect of the pendant crown ethers, (monoaza-15-crown-5 and monoazo-18-crown-6), beening negligible, the identity of the ester functional group in the phosphinate structure exerted sizable influence on toxicity. Thus, phosphinate derivative with octyl or propyl ester group showed somewhat higher toxicity than that with ethyl ester group.

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Analysis of Water Quality caused by Improvement of Sewage Treatment Plant in Masan Bay (하수처리장 개선이 마산만 수질에 미치는 영향분석)

  • Oh Hyun-Taik;Goo Jun-Ho;Park Sung-Eun;Choi Yun-Sun;Jung Rae-Hong;Choi Woo-Jeung;Lee Won-Chan;Park Jong-Soo
    • Journal of Environmental Science International
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    • v.14 no.8
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    • pp.777-783
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    • 2005
  • For the sustainable management of marine ecosystem in Masan Bay, we have to assess the carrying capacity and standard of target water quality. In this research, we assume that all pollutants loads are treated in Dukdong sewage treatment plant, then we simulate the physical-biological model for prediction water quality for the achievement of standard water quality. In 2001 year, for the achievement of COD 2.5 mg/L, we need to reduce COD $90\%$, nitrogen $30\%$, phosphate $90\%$ than that of the present value, According to these results, the water quality of sewage treatment plant is required to treat COD 13.5 mg/L, nitrogen 33.3 mg/L, phosphate 6,0 mg/L. If the sewage treatment plant will be expanded much larger in 2011, it will need to be treated in COD 6.6 mg/L, nitrogen 2.5 mg/L, phosphate 5 mg/L for the achievement of water quality standard in COD 2.5 mg/L.

Analysis on Proportional Daily Weight Increase of Swine Using Machine Learning (기계학습을 이용한 비육돈의 비율일당증체분석)

  • Lee, Woongsup;Hwang, Sewoon;Kim, Jonghyun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.183-185
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    • 2015
  • Recently, big data analysis based on machine learning has gained popularity and many machine learning techniques have been applied to the field of agriculture. By using machine learning technique to analyze huge number of samples of biological and environmental data, new observations can be found. In this research, we consider the estimation of proportional daily weight increase (PDWI) based on measurement data from experimental swine farm. In order to derive the exact formulation for PDWI estimation, we have used measured value of mean, daily maximum, daily minimum of temperature, humidity, CO2, wind speed and measured PDWI values. Based on collected data, we have derived equation for PDWI estimation using tree-based algorithm. In the derived formulation, we have found that the daily average temperature is the most dominant factor that affects PDWI. Our results can be applied to pig farms to estimate the PDWI of swine.

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Pretreatment of Vegetable Oil Using Ion-exchange Resin and Biodiesel Production (이온교환수지를 이용한 식물유지의 전처리 및 바이오디젤 생산)

  • Hong, Yeon-Ki;Huh, Yun-Suk;Hong, Won-Hi;Oh, Sung-Woo
    • Clean Technology
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    • v.13 no.2
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    • pp.104-108
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    • 2007
  • Biodiesel is a fatty acid alkyl ester produced by chemical reaction of a vegetable oil or animal fat and an alcohol. It is getting attention as a clean alternative energy that can replace gas oils. In this study, strong acidic ion exchange resin was introduced in the pretreatment process of the used cooking oil and rapeseed oil to enhance the conversion of the oil to the biodiesel by removing FFA(free fatty acid). More than 90% FFA was removed. Dry resins showed higher FFA removal efficiency than wet resins. Using transesterification the conversion of triglyceride into fatty acid methyl ester was raised up to 98%. These results can be applicable to the pretreatment of biodiesel feedstocks having high acidic value.

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Development Paradigm of Repression and Desire Embodied by Body and Clothing (몸·복식에서 억압과 욕망의 패러다임 개발)

  • Jeong, Ki-Sung;Kim, Min-Ja
    • Journal of the Korean Society of Costume
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    • v.63 no.6
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    • pp.97-112
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    • 2013
  • In this study, physical, social and psychological repression embodied by the body and clothing are referred to instinctual, power and creative desires, respectively, from the point of biological, social and aesthetic views. Desire refers to a behavior to overcome men's imperfections with individual security, sense of belonging and the pursuit of an ideal, which are obtained by living as a social creature. Repression through the body is sub-categorized depending on whether it is temporary or permanent. Repression expressed through clothing is seen through revealing/concealing, contraction/expansion, and deconstruction/ reconstruction. What enables human beings to embrace changes in fashion without fierce resistance or backlash is the changes of formativeness demonstrated by repression through the body and clothing. The aesthetic values drawn from the exhibition of repression and on the body and clothing are categorized into narcissism, fetishism and aestheticism. While narcissism is an instinctive desire grounded on the originality and confidence of the self that results in refusing repression, fetishism is a desire for power that expedites repression in the pursuit of materialistic value or sexual fantasy. Aestheticism is a desire for creativity that symbolizes the body-and-clothing repression in the pursuit of aesthetic idealism. Repression evokes desire, and the pursuit of desire leads to another repression. The aesthetic values of desire for instinct, power and creativity can be substituted with each other for interpretation according to the attitudes of an initiator, a user and a spectator.