• Title/Summary/Keyword: biological stability

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Biomechanical Analysis of Body Balance

  • Jeong, Byung-Yong
    • Journal of Biomedical Engineering Research
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    • v.9 no.2
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    • pp.233-238
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    • 1988
  • Human body sways continuously to maintain balance during upright stance. A computer-aided instrumentation system using a force platform has been developed to investigate the body balance. The Kistler force platform and amplifiers were only used to obtain the precise measurements, and the data acquisition and analysis software operating on an IBM PC with A/D converter was developed. This study presents methods for the display of platform center of pressure data on stability study. This system can be used as a tool in evaluating the man's ability to balance and disorders of the nervous system.

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Aminoacyl-tRNA Synthetase Cofactor, p43, is a Novel Cytokine and an Immune Modulator: Implications for Autoimmune Diseases and Bacterial Infections

  • Kim, Sung-Hoon
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.77-77
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    • 2003
  • p43 is a protein with complex biological activities. It is first found as a protein associated with macromolecular tRNA synthetase complex. Within this complex, p43 specifically interacts with arginyl-tRNA synthetase to help the substrate tRNA binding to the enzyme. It is also necessary for the cellular stability of arginyl-tRNA synthetase and the molecular association of a few complex-forming tRNA synthetases. (omitted)

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Proline Effect on Structure and Activity of Antimicrobial Peptides

  • Suh, Jeong-Yong;Park, Byong-Seok
    • Proceedings of the Korean Biophysical Society Conference
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    • 1998.06a
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    • pp.19-19
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    • 1998
  • Structure and activity of a helical antimicrobial peptide with a central proline (P14) and its alanine derivative (P14A) were investigated by NMR spectroscopy and biological assay. Chemical shift analysis showed that both of the peptides formed curved helix and P14 showed diminished stability near proline due to hindrance of hydrogen bonding by proline.(omitted)

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A Study on EMG Functional Recognition Vsing Reduced-Connection Network (연결 축소 회로망을 이용한 EMG 신호 기능 인식에 관한 연구)

  • 조정호;최윤호
    • Journal of Biomedical Engineering Research
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    • v.11 no.2
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    • pp.249-256
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    • 1990
  • In this study, LPC cepstrum coefficients are used as feature vector extracted from AR model of EMG signal, and a reduced-connection network whlch has reduced connection between nodes is constructed to classify and recognize EMG functional classes. The proposed network reduces learning time and improves system stability Therefore it is Ehown that the proposed network is appropriate in recognizing function of EMG signal.

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Picosecond Protein Fluorescence and Time-Resolved $Eu^{3+}$ Luminescence Spectroscopic Studies on the Roles of $Ca^{2+}$ in Subtilisin Carlsberg

  • Lee, Sunbae;Jang, Du-Jeon
    • Proceedings of the Korean Biophysical Society Conference
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    • 1997.07a
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    • pp.44-44
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    • 1997
  • Ca$^{2+}$ is one of the most common metal ions associated with proteins, playing more or less well-defined functional roles in biological activities. In protease, the presence of $Ca^{2+}$ slows down autolysis and enhances thermal stability. Subtilisin, one of the best studied proteases, is known to have two $Ca^{2+}$ -binding sites.(omitted)

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Synthetic Cephalosporin Derivatives

  • Oh, Chang-Hyun;Park, Sang-Woo;Cho, Jung-Hyuck
    • Bulletin of the Korean Chemical Society
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    • v.11 no.4
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    • pp.323-327
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    • 1990
  • The synthesis and some biological properties of $7{\beta} $-[2-(Z)-(2-aminothiazole-4-yl)-2-(N-substitutedcar bonyl)ethoxyiminoacetamido]-3-vinyl-3-cephem-4- carboxylic acid are described. The effect of substituents on the carbamoly group in the 7-side chain were investigated in order to improve antibacterial activities. Two of these new orally active $7{\beta} $-lactam derivatives showed wide expanded antimicrobial activities against Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, as well as good stability to $7{\beta} $ -lactamases.

Study of Collective Synchronous Dynamics in a Neural Network Model

  • Cho, Myoung Won
    • Journal of the Korean Physical Society
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    • v.73 no.9
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    • pp.1385-1392
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    • 2018
  • A network with coupled biological neurons provides various forms of collective synchronous dynamics. Such phase-locking dynamics states resemble eigenvectors in a linear coupling system in that the forms are determined by the symmetry of the coupling strengths. However, the states behave as attractors in a nonlinear dynamics system. We here study the collective synchronous dynamics in a neural system by using a novel theory. We exhibit how the period and the stability of individual phase-locking dynamics states are determined by the characteristics of synaptic couplings. We find that, contrary to common sense, the firing rate of a synchronized state decreases with increasing synaptic coupling strength.

Straightforward synthesis of 4'${\alpha}$-C-hydroxymethyl branched novel carbocyclic nucleosides

  • Oh, Jung-Hyo;Kim, Kwan-Woo;Hong, Joon-Hee
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.354.1-354.1
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    • 2002
  • Carbocyclic nucleosides are unique class in which a methylene group replaces the oxygen in the furan, which result in metabolic stability to endogenous phosphorylase. The biologically active natural carbocyclic nucleosides such as aristeromycin and neplanocin were found to possess interesting biological properties including antiviral and antitumor activity. (omitted)

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Fish Compositions and Distribution Characteristics in the Upstream and Downstream Region of Seungchon Weir (승촌보의 상류구간 및 하류구간에서 어류 종 조성 및 분포특성)

  • Park, Chan-Seo;Choi, Ji-Woong;Lee, Jae Hoon;Lim, Byung Jin;Park, Jong-Hwan;An, Kwang-Guk
    • Journal of Korean Society on Water Environment
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    • v.29 no.2
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    • pp.196-203
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    • 2013
  • Seungchon Weir was constructed in 2010 on the downstream region of Yeongsan River watershed for four major river projects. The purpose of our study was to determine whether fish compositions and distributions differ between the upper ($U_w$) and lower regions ($L_w$) of Seungchon Weir during May - December 2011 along with hydroacoustic fish surveys using Eco-Sounder monitoring ($E_SM$) technique. Total number of fish species sampled by conventional fish sampling at all sites was 29, and 21 and 24 species occurred in the $U_w$ and $L_w$, respectively. Most dominant species was Hemiculter eigenmanni (43%) in the $U_w$ and Opsaiichthys uncirostris amurensis (21%) in the $L_w$, indicating a distinct differences of the species composition. According to hydroacoustic approach of ESM, fish density was significantly higher (p < 0.05) in the $L_w$ section of 250 m than any other sections, This outcome indicates that fishes moving toward the upstream were blocked by weir construction. According to analysis of tolerance guilds, tolerant species (TS) were made of 88% and 79% in the $U_w$ and $L_w$ region, respectively, while the proportions of sensitive species were < 0.1% of the total in the both regions. Trophic guild analysis showed that the proportion of omnivore species were 58% and 40% in the $U_w$ and $L_w$ region, respectively, while insectivores were made of 16% and 21% in the $U_w$ and $L_w$ region, respectively. Both analyses of tolerance guilds and trophic guilds indicate the biological degradation of the waterbody. Fish community structure analysis, based on species diversity, dominance, and evenness indices, showed higher community stability in the $L_w$ region than $U_w$ region. Exotic species of largemouth bass were largely increased in this survey (14%), compared to the past (< 1%), indicating a modification of fish trophic structure.

Ethanol Electro-Oxidation and Stability of Pt Supported on Sb-Doped Tin Oxide (안티몬 도핑된 주석 산화물에 담지된 백금 촉매의 에탄올 산화 반응 및 안정성 연구)

  • Lee, Kug-Seung;Park, Hee-Young;Jeon, Tae-Yeol;Sung, Yung-Eun
    • Journal of the Korean Electrochemical Society
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    • v.11 no.3
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    • pp.141-146
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    • 2008
  • Electrocatalytic activities and stabilities of Pt supported on Sb-doped $SnO_2$ (ATO) were examined for ethanol oxidation reactions. Pt colloidal particles were deposited on ATO nanoparticles (Pt/ATO) and the prepared electrocatalysts were characterized by X-ray diffraction, transmission electron microscopy (TEM), and cyclic voltammetry. Electrochemical activity of the Pt/ATO for ethanol electro-oxidation was compared to those of Pt supported on carbon (Pt/C) and commercial PtRu/C. The activitiy of the Pt/ATO was much higher than those of the Pt/C and commercial PtRu/C. The Pt/ATO exhibited much higher electrochemical stabilities than the Pt/C in 0.5M ${H_2}{SO_4}$ and in 0.5M ${H_2}{SO_4}$/1M ${C_2}{H_5}OH$. According to TEM, the growth rate of Pt particles was lower in the Pt/ATO than it was in the Pt/C. The ATO nanoparticle appears to be a promising support material that promotes electrochemical reactions and stabilizes catalyst particles in direct ethanol fuel cell.